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Christopher Whyte

@christopherjwhyte.bsky.social
715 followers 593 following 40 posts

Theoretical neuroscientist. Postdoc in the Adaptive Dynamical Systems group at USYD. Interested in neural dynamics, decisions, and consciousness. www.ChristopherJWhyte.com

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Reposted by Christopher Whyte
hakwan lau @hakwan.bsky.social · 17/09/2026
we started out just wanting to point out that, despite its popularity, comparing hits vs misses in detection tasks is actually not a very good way to study subjective experience / consciousness. but we ended up expanding it to make it relevant for clinical stuff too led by @tomnakamura.bsky.social
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Borjan (Boki) Milinković @neuromorphicboki.bsky.social · 18/09/2026
📜 FINALLY OUT! 📜 In @imagingneurosci.bsky.social (@mitpress.bsky.social), myself, Lionel Barnett, @anilseth.bsky.social, Olivia carter, and @thomasandrillon.bsky.social, advance approaches of #multiscale #emergence and it's application to EEG across #conscious #states. Buckle up 👇 1/n
direct.mit.edu
Emergent multiscale organisation of neural dynamics fragments in anaesthesia
Abstract. Conscious experience depends on the coordinated activity of neural processes that span multiple scales: from synapses to whole-brain dynamics. A recently introduced measure, dynamical indepe...
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Anil Seth @anilseth.bsky.social · 17/09/2026
1/ Conscious AI and Biological Naturalism. A long time in the making, but the full collection is *out now* in Behavioural and Brain Sciences I deeply thank all my many commentators for their wise, broad, and deep opinions on this critical topic.I also thank them for their saintly patience. 🙏🏽
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Shervin Safavi @neuroprinciplist.bsky.social · 09/06/2026
1/11 Happy to share our TICS paper on using the flexibility of one of the most basic cognitive functions, perception, to understand one of the most complex cognitive dysfunctions, psychiatric conditions (also my first formal work in computational psychiatry 🎉) 📄: www.cell.com/trends/cogni... 🧵 : 👇
cell.com
Perceptual multistability: a multifaceted window into brain dysfunctions
Perceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics a...
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Erica Busch @elbusch.bsky.social · 11/06/2026
Our new paper is out this week in Nature Neuroscience! www.nature.com/articles/s41... We built a BCI that works with the brain's natural geometry — and we found that people could learn to play a video game with their brains in <1 hr of training. This efficiency is groundbreaking & here's why:
nature.com
Human learning of noninvasive brain–computer interfaces via manifold geometry - Nature Neuroscience
Busch et al. use nonlinear neural manifolds to help humans gain rapid control over a noninvasive brain–computer interface, allowing them to learn how to play a video game with real-time fMRI neurofeed...
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Sean Carroll @seanmcarroll.bsky.social · 27/04/2026
Mindscape 352 | Bing Brunton @bingbrunton.bsky.social on Connecting the Connectome to the Body. #MindscapePodcast www.preposterousuniverse.com/podcast/2026...
Title card for Mindscape Podcast episode with Bing Brunton.
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Trends in Cognitive Sciences @cp-trendscognsci.bsky.social · 11/04/2026
Online Now: Perceptual multistability: a multifaceted window into brain dysfunctions
dlvr.it
Perceptual multistability: a multifaceted window into brain dysfunctions
Perceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics and information integration during percept formation often distinguish clinical from nonclinical populations. Computational psychiatry can elucidate these variations through two primary approaches: (i) Bayesian modeling, which treats perception as an unconscious inference, and (ii) an active, information-seeking perspective (e.g., reinforcement learning), which frames perceptual switches as internal actions. Our synthesis aims to leverage multistability to bridge these computational psychiatry subfields, linking human and animal studies as well as connecting behavior to underlying neural mechanisms. Perceptual multistability emerges as a promising noninvasive tool for clinical applications, facilitating translational research and enhancing our mechanistic understanding of cognitive processes and their impairments.
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Borjan (Boki) Milinković @neuromorphicboki.bsky.social · 14/04/2026
🎉 📜 NEW #PREPRINT !! 📜 🎉 Spearheaded by Adam Barrett we tried to tackle some of the challenges of IIT. We confront aspects worth delving into, with an incredible team of collaborators, inc. Pedro Mediano, @frosas.bsky.social, Daniel Bor, Lionel Barnett, and @anilseth.bsky.social.
arxiv.org
Integrated information theory: the good, the bad and the misunderstood
The integrated information theory of consciousness (IIT) is uniquely ambitious in proposing a mathematical formula, derived from apparently fundamental properties of conscious experience, to describe ...
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Shervin Safavi @neuroprinciplist.bsky.social · 07/04/2026
If you need a method to infer causality from neural data, even when the signal is short, check our recent paper: Paper: joss.theoj.org/papers/10.21... Code: github.com/CMC-lab/Tran...
joss.theoj.org
TranCIT: Transient Causal Interaction Toolbox
Nouri et al., (2025). TranCIT: Transient Causal Interaction Toolbox. Journal of Open Source Software, 10(116), 9302, https://doi.org/10.21105/joss.09302
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Brendan Harris @brendanjohnharris.bsky.social · 23/03/2026
How does the visual cortex coordinate neural activity over spatial and temporal scales? We found broad θ waves organize local γ bursts and spiking, forming a flexible spatiotemporal code to multiplex feedforward/feedback signals. Now out in full @natcomms.nature.com: doi.org/10.1038/s414... 🧵
Schematic of theta waves and gamma packets recorded from the mouse visual cortex
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Sam Gershman @gershbrain.bsky.social · 13/02/2026
I've been inspired to become a founder of a new startup that develops brain-to-brain interface technology. It's called Talk. We're going to reinvent communication for the digital age. The best part is that we're able to zero-shot transfer the full computational stack already used by your brain!
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Annie G. Bryant @anniegbryant.bsky.social · 27/01/2026
The extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that I’ve graduated 🤠 This figure shows the 9 atlases included (and counting)! Preprint: www.biorxiv.org/content/10.6... Website: anniegbryant.github.io/subcortex_vi...
Nine subcortical/cerebellar atlases included in the subcortex_visualization Python package (and subcortexVisualizationR package in R). The atlases are depicted in two-dimensional vector graphic format.
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Philip Ball @philipcball.bsky.social · 27/12/2025
Finally, after much delay from the BBC, Marnie Chesterton's "What Is Quantum?" is being broadcast at 9.30 am on Radio 4 on Tues 30th Dec. Recorded on Helgoland in the summer, with input from the leading figures in quantum mechanics (and me). www.bbc.co.uk/programmes/m...
bbc.co.uk
BBC Radio 4 - What Is Quantum?
Marnie Chesterton travels to the birthplace of quantum theory armed with just one question
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Dan Levenstein @dlevenstein.bsky.social · 29/10/2025
Really hoping bifurcations are the new manifolds. What a time to be alive 🥲
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Anil Seth @anilseth.bsky.social · 17/10/2025
1/ "Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans" - out now in @plosbiology.org, led by Michele Colombo, Jacopo Favaro, & Marcello Massimini. 🧠
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Christopher Whyte @christopherjwhyte.bsky.social · 21/10/2025
The final paper of my PhD is now out as a preprint. This is a follow-up piece in series of two companion papers modelling awareness and suppression in a new variant of continuous flash suppression. arxiv.org/abs/2510.17154 🧵 1/3
arxiv.org
A Minimal Quantitative Model of Perceptual Suppression and Breakthrough in Visual Rivalry
When conflicting images are presented to either eye, binocular fusion is disrupted. Rather than experiencing a blend of both percepts, often only one eye's image is experienced, whilst the other is su...
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Paul Middlebrooks @braininspired.bsky.social · 10/09/2025
What changes and what stays the same as you scale from single neurons up to local populations of neurons up to whole brains? Michael and Mac @macshine.bsky.social on the systems approach to study brains across scales. braininspired.co/podcast/220/
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Anikó Kusztor @anikokusztor.bsky.social · 03/09/2025
Thank you so much for having me!! I always have a blast chatting with @bethfisher.bsky.social and this time was no different! 💕 Also I loved your reflections in the end and how both of you have change your mind perhaps a bit through sharing your experiences with each other. So cool and precious!
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Andrew Corcoran @corcorana.bsky.social · 03/09/2025
The first major output of the @templetonworld.bsky.social @arc-intrepid.bsky.social adversarial collaboration testing IIT & predictive processing theories of consciousness is out now arxiv.org/abs/2509.00555
arxiv.org
Integrated information and predictive processing theories of consciousness: An adversarial collaborative review
As neuroscientific theories of consciousness continue to proliferate, the need to assess their similarities and differences -- as well as their predictive and explanatory power -- becomes ever more pr...
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Claire O'Callaghan @claireocallaghan.bsky.social · 29/08/2025
Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level). If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...
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Claire O'Callaghan @claireocallaghan.bsky.social · 25/08/2025
OHBM Oz rego + abstracts now open. Get amongst it!
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Ann Kennedy @antihebbiann.bsky.social · 20/08/2025
I wrote a Comment on neurotheory, and now you can read it! Some thoughts on where neurotheory has and has not taken root within the neuroscience community, how it has shaped those subfields, and where we theorists might look next for fresh adventures. www.nature.com/articles/s41...
nature.com
Theoretical neuroscience has room to grow
Nature Reviews Neuroscience - The goal of theoretical neuroscience is to uncover principles of neural computation through careful design and interpretation of mathematical models. Here, I examine...
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Luke Seaber @thelong1930s.bsky.social · 20/08/2025
It’s touching and wonderful the amount of people saying reading Pratchett has made them a better person, myself included. Was it @adamchapman.bsky.social I remembering saying that his downstream positive effect on UK society is something we should increasingly be considering as his readers age?
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Annie G. Bryant @anniegbryant.bsky.social · 20/08/2025
🎊Ain’t no party like a thesis submission party🎊 Honored to have submitted my PhD as a recipient of the Paulette Isabel Jones Career Development Award from The University of Sydney! Thank you x1000000 to MVP supervisor @bendfulcher.bsky.social & co-supervisor @macshine.bsky.social 😊
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Mac Shine @macshine.bsky.social · 18/08/2025
I need some help from the #neuroskyence Bluesky-verse. Anyone know the source of this ~quote from Walter J. Freeman Jr.: "the secrets of the brain are hidden by two of God’s own firewalls: neurobiology and non-linear dynamics". I read it yrs ago but can't seem to find my way back to the source.
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Claire O'Callaghan @claireocallaghan.bsky.social · 15/08/2025
Position open for a neuroimaging focused postdoc to come work with us in Sydney Feel free to get in touch for a chat if you have any questions about it :) usyd.wd105.myworkdayjobs.com/en-GB/USYD_E...
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Alex Fornito @alexfornito.bsky.social · 02/08/2025
Interested in cortical wave dynamics? Check out our new preprint led by J Cruddas with @jchrispang.bsky.social where review the physics and physiology of cortical waves and their implications for psychological function: osf.io/preprints/ps... @nsb-lab.bsky.social
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allen institute @alleninstitute.org · 28/07/2025
New electron microscopy study in @nature.com Neuroscience finds that layer 5 ET neurons mostly connect to inhibitory cells locally, esp. those suppressing other excitatory cells, suggesting a "winner-take-all" system. 🧠📈 www.nature.com/articles/s41...
nature.com
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex - Nature Neuroscience
This study maps the connections of layer 5 pyramidal neurons in the mouse cortex, revealing distinct local and intercortical wiring patterns, and provides an open framework for exploring the connectiv...
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Nadine Dijkstra @nadinedijkstra.bsky.social · 23/07/2025
After five years of confused staring at Greek letters, it is my absolute pleasure to finally share our (with @smfleming.bsky.social) computational model of mental imagery and reality monitoring: Perceptual Reality Monitoring as Higher-Order inference on Sensory Precision ✨ osf.io/preprints/ps...
osf.io
OSF
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Moritz Kriegleder @mokriegleder.bsky.social · 21/07/2025
finally recovered from all the thought provoking discussions I had at @assc28.bsky.social! presented a meta analysis of the current state of consciousness science and why we should leave theory convergence behind (based on work with @mnoichl.bsky.social & @niccolonegro.bsky.social)
moritz kriegleder presenting a slide on the current state of consciousness science
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Borjan (Boki) Milinković @neuromorphicboki.bsky.social · 20/07/2025
📜🪇[PUBLISHED]: NEW PREPRINT!🪇📜 I am incredibly excited to announce that we have published our paper on how "Dynamical independence reveals anaesthetic specific fragmentation of emergent structure in neural dynamics" w@thomasandrillon.bsky.social @anilseth.bsky.social Barnett, Carter Strap in! 1/n
biorxiv.org
Dynamical independence reveals anaesthetic specific fragmentation of emergent structure in neural dynamics
Conscious experience depends on the coordinated activity of neural processes that span multiple scales--from synapses to whole-brain dynamics. A recently introduced measure, dynamical independence, id...
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Matteo Carandini @carandinilab.net · 18/07/2025
A new study led by @timothysit.bsky.social reveals that different layers of mouse V1 integrate visual and non-visual signals differently. Activity is dominated by vision (or spontaneous fluctuations) in L2/3 and by movement in L5. This leads to different geometries. www.biorxiv.org/content/10.1...
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Ben Fulcher @bendfulcher.bsky.social · 16/07/2025
New paper! We introduce an efficient set of statistical features for fMRI time series (calibrated on mouse manipulation experiments and tested on mouse and human data): catchaMouse16. Paper: doi.org/10.52294/001... Code (python/Matlab/C): github.com/DynamicsAndN...
logo of mouse holding banner representing a time-series feature vector
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Andrew Saxe @saxelab.bsky.social · 11/07/2025
Pairs well with www.nature.com/articles/s41... “Our results indicate that individual V1 neurons do not signal how the actual visual input deviates from the animal’s predictions, as postulated within the predictive coding framework” Thrilling to see a major theory get tested!
nature.com
Cooperative thalamocortical circuit mechanism for sensory prediction errors - Nature
Experiments in mice show that a cortico-thalamic circuit generates prediction-error signals&nbsp;in primary visual cortex that amplify visual input&nbsp;that deviates from animals’&nbsp;expectations.
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Blake Richards @tyrellturing.bsky.social · 11/07/2025
1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex: www.biorxiv.org/content/10.1... I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction. But... 🧠📈 🧪
biorxiv.org
Sensory responses of visual cortical neurons are not prediction errors
Predictive coding is theorized to be a ubiquitous cortical process to explain sensory responses. It asserts that the brain continuously predicts sensory information and imposes those predictions on lo...
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theASSC @theassc.bsky.social · 10/07/2025
Congratulations to Abhilash Dwarakanath who won this year's William James Prize for his brilliant work on the b istability of prefrontal states gating access to consciousness. You can read his paper here: www.cell.com/neuron/fullt...
cell.com
Bistability of prefrontal states gates access to consciousness
Mesoscale ensemble recordings in the vlPFC during no-report binocular rivalry show that stochastic prefrontal state fluctuations are associated with spontaneous changes in the content of consciousness...
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Jorge Mejias @jorgefmejias.bsky.social · 08/07/2025
New paper @pnas.org with Lola Beerendonk, Jan Willem de Gee, Simon van Gaal and others, on pharmacological shifts of performance. We combine psychophysics and pupillometry with computational modeling to provide interesting insights linked to PV-SST-VIP circuits: www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Sean Carroll @seanmcarroll.bsky.social · 30/06/2025
Mindscape 320 | Solo: Complexity and the Universe. Our cosmos was once simple, and someday will be simple again. We currently live in the complicated, exciting era of universal history! Enjoy it while it lasts. #MindscapePodcast www.preposterousuniverse.com/podcast/2025...
Title card for podcast episode on complexity and the universe.
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Ben Fulcher @bendfulcher.bsky.social · 25/06/2025
New preprint! Why are long-range connectomic interactions in the cortex dominant in shaping dynamics in some experiments but apparently negligible in others? We (w/ R Maran, @elimuller.bsky.social) address this question by studying a new hybrid model of cortical dynamics. arxiv.org/abs/2506.19800
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Dan Levenstein @dlevenstein.bsky.social · 30/06/2025
This paper, from @smellosopher.bsky.social et al, is a well-designed spherical cow with a lot of 🥛 to give. Has been quite influential in how I think of #NeuroAI and ANNs as models for the brain 🐮 onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Milking a spherical cow: Toy models in neuroscience
Highly idealised models have long played a role in physics, valued not for their empirical accuracy but for their ability to clarify conceptual puzzles, foster tool development, and suggest new direc...
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Tim Vogels @tpvogels.bsky.social · 02/06/2025
We just pushed “Memory by a 1000 rules” onto bioRxiv, where we use clever #ML to find #plasticity quadruplets (EE, EI, IE, II) that learn basic stability in spiking nets. Why is it cool? We find 1000s!! of solutions, and they don’t just stabilise. They #memorise! www.biorxiv.org/content/10.1...
biorxiv.org
Memory by a thousand rules: Automated discovery of functional multi-type plasticity rules reveals variety &amp; degeneracy at the heart of learning
Synaptic plasticity is the basis of learning and memory, but the link between synaptic changes and neural function remains elusive. Here, we used automated search algorithms to obtain thousands of str...
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Annie G. Bryant @anniegbryant.bsky.social · 29/06/2025
#OHBM2025 was a blast -- the perfect way to celebrate submitting my PhD thesis with y'all 🎉 It was an honor (and so fun!) to represent the Aussie imaging community alongside a fab panel in the LOC Symposium, sharing my final thesis work on homotopic connectivity: www.biorxiv.org/content/10.1...
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Michelle Greene @mgreenephd.bsky.social · 09/06/2025
I'm excited to announce that my lab's open textbook on Scientific Computing for Cognitive Neuroscience (v1.0) has just gone live! Our goal is to help mend the gap between the computational skills needed by cognitive neuroscience, and typical curricula that don't yet include it. 1/3
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Nadine Dijkstra @nadinedijkstra.bsky.social · 05/06/2025
I am so excited to share that our paper 'A neural basis for distinguishing imagination from reality' is now published in @cp-neuron.bsky.social! 🧠✨ See thread below! doi.org/10.1016/j.ne...
doi.org
Redirecting
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John Butler @jslbutler.bsky.social · 04/06/2025
New pre-print with Rebecca Brady on mathematical models to simulate audio-visual reaction time tasks. This debutant paper has three main goals: 1. To simulate different mechanisms of multisensory integration and compare with the behavioural findings 1/8
media.tenor.com
a black and white photo of a woman in a wedding dress .
ALT: a black and white photo of a woman in a wedding dress .
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Mel Goodale @action-brain.bsky.social · 03/06/2025
CIFAR invites applications for senior PhD and postdocs to participate in the Neuroscience of Consciousness Winter School, held in Montebello, Canada Dec 10-12, 2025. The Winter School is hosted by members of CIFAR’s Brain, Mind, and Consciousness program. Please repost. cifar.ca/next-generat... 🧠🧪
Dog-sled going past the Le Château Montebello.Main public room in Le Château Montebello decorated for Christmas. The building is the world's largest "log cabin".Le Château Montebello is situated on the banks of the Ottawa river, separating Quebec and Ontario.Group photo the school of 2018 at the Winter school on the Neuroscience of Consciousness
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Maciek Szul @maciekszul.bsky.social · 02/06/2025
🚨🚨🚨PREPRINT ALERT🚨🚨🚨 Neural dynamics across cortical layers are key to brain computations - but non-invasively, we’ve been limited to rough "deep vs. superficial" distinctions. What if we told you that it is possible to achieve full (TRUE!) laminar (I, II, III, IV, V, VI) precision with MEG!
Overview of the simulation strategy and analysis. a) Pial and white matter boundaries
surfaces are extracted from anatomical MRI volumes. b) Intermediate equidistant surfaces are
generated between the pial and white matter surfaces (labeled as superficial (S) and deep (D)
respectively). c) Surfaces are downsampled together, maintaining vertex correspondence across
layers. Dipole orientations are constrained using vectors linking corresponding vertices (link vectors).
d) The thickness of cortical laminae varies across the cortical depth (70–72), which is evenly sampled
by the equidistant source surface layers. e) Each colored line represents the model evidence (relative
to the worst model, ΔF) over source layer models, for a signal simulated at a particular layer (the
simulated layer is indicated by the line color). The source layer model with the maximal ΔF is
indicated by “˄”. f) Result matrix summarizing ΔF across simulated source locations, with peak
relative model evidence marked with “˄”. g) Error is calculated from the result matrix as the absolute
distance in mm or layers from the simulated source (*) to the peak ΔF (˄). h) Bias is calculated as the
relative position of a peak ΔF(˄) to a simulated source (*) in layers or mm.
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Michael Pereira @meaperei.bsky.social · 01/06/2025
New “version of record” in @elife.bsky.social! ‬ We recorded neurons in the thalamus and subthalamic nucleus of humans and found both sensory- and perception-selective neurons with two distinct latencies! 7-year project with @nfaivre.bsky.social + @foscobernasconi.bsky.social. A short thread 👇
elifesciences.org
Subcortical correlates of consciousness with human single neuron recordings
Subcortical brain structures contain neurons encoding subjective reports of stimulus detection in human participants, suggesting a role for conscious perception.
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Christopher Whyte @christopherjwhyte.bsky.social · 02/06/2025
New preprint modelling suppression depth in binocular rivalry and continuous flash suppression with Hugh Wilson, @macshine.bsky.social, & David Alais
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