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Chatel-Chaix Lab

@chatel-chaixlab.bsky.social
30 followers 36 following 5 posts

A research laboratory dedicated to the study of flaviviruses and SARS-CoV-2

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Reposted by Chatel-Chaix Lab
Nature @nature.com · 20/02/2025
Excess mitochondrial fusion is averted by stress-activated regulators, preventing the potentially harmful release of mitochondrial DNA go.nature.com/3EGN5QL
go.nature.com
Putting the brakes on mitochondrial fusion to prevent escape of mitochondrial DNA
Organelle network is regulated to prevent cellular inflammation.
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Reposted by Chatel-Chaix Lab
Canadian Society for Virology @cansocvirol.bsky.social · 01/02/2025
Opportunities for CSV trainees! Apply for the CSV Lab Exchange Program to fund research collaborations or training—deadline: April 1. Details: www.csv-scv.ca/en/lab-excha... Submit your abstract by March 1 to present at the CSV virtual seminar on April 11: forms.gle/zw2YdxQ2kLcc...
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Reposted by Chatel-Chaix Lab
Clive McKimmie @clive-mckimmie.bsky.social · 01/02/2025
We expected it to be bad, but so quickly?
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Reposted by Chatel-Chaix Lab
Holden Thorp @holdenthorp.bsky.social · 31/01/2025
The latest from @science.org on the situation at NIH. @meredithwadman.bsky.social and Jocelyn Kaiser getting all the info they can. www.science.org/content/arti...
science.org
NIH is purging Trump-targeted programs—but is sparing existing grants, so far
Chaos extends to CDC, which is shuttering websites in “data apocalypse”
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Reposted by Chatel-Chaix Lab
Nature @nature.com · 29/01/2025
Despite carrying lethal pathogens, bats rarely develop disease — a phenomenon that has intrigued scientists for decades go.nature.com/4hBWzL0
go.nature.com
Viral tolerance enabled by a bat-specific genomic tweak
Comparative genomics reveals how virus-carrying bats resist disease.
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Reposted by Chatel-Chaix Lab
Julien Pompon @julienpompon.bsky.social · 24/01/2025
preprint advancing #flavivirus transmission understanding: 1. Flavivirus-infected #mosquito saliva always contain sfRNA inside lipide #vesicles. 2. Salivary sfRNA increases transmission by inhibiting MDA5-mediated interferon signalling. www.biorxiv.org/content/10.1...
biorxiv.org
Multiple orthoflaviviruses secrete sfRNA in mosquito saliva to promote transmission by inhibiting MDA5-mediated early interferon response
Numerous orthoflaviviruses transmitted through the bites of different mosquito species infect more than 500 million people annually. Bite-initiated skin infection represents a critical and conserved s...
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Chatel-Chaix Lab @chatel-chaixlab.bsky.social · 23/01/2025
Congrats, it is finally out.
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Reposted by Chatel-Chaix Lab
Nature @nature.com · 22/01/2025
🇭🇳 Contribute to the community 🇮🇪 Publish papers, but also be publicly visible 🇺🇸 Publication record, impact, and research quality This is how to become a professor where you are go.nature.com/3WpESGE
go.nature.com
Want to become a professor? Here’s how hiring criteria differ by country
Huge analysis identifies regional variations in the criteria that institutions use to move researchers up the ranks.
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Chatel-Chaix Lab @chatel-chaixlab.bsky.social · 22/01/2025
And thank you @fondsrechercheqc.bsky.social for the salary/sholarship support (to me, Dr. Hulea, Aïcha Sow, Dr. Freppel and Dr. Tremblay) while we were performing this research.
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Chatel-Chaix Lab @chatel-chaixlab.bsky.social · 22/01/2025
Finally, this would not have been possible without the financial support of the Canadian Institutes of Health Research, the Armand-Frappier Foundation and INRS
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Chatel-Chaix Lab @chatel-chaixlab.bsky.social · 22/01/2025
Huge congratulations to Wesley Freppel, the first author and to our team who all work very hard to get this out. Thank you to our collaborators (Hulea, Scaturro, Neufeldt, Lamarre, Girard and Pichmaier labs) for their critical help in this work.
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Chatel-Chaix Lab @chatel-chaixlab.bsky.social · 22/01/2025
As a first post on Bluesky, I am very proud to share our latest research published in @cp-iscience.bsky.social on how dengue and Zika viruses hijack mitochondrial functions in respiration and apoptosis by altering their contacts with th eendoplasmic reticulum. www.sciencedirect.com/science/arti...
sciencedirect.com
Dengue virus and Zika virus alter endoplasmic reticulum-mitochondria contact sites to regulate respiration and apoptosis
During infection, dengue virus (DENV) and Zika virus (ZIKV), two (ortho)flaviviruses of public health concern worldwide, induce alterations of mitocho…
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