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Chatel-Chaix Lab

@chatel-chaixlab.bsky.social
30 followers 36 following 5 posts

A research laboratory dedicated to the study of flaviviruses and SARS-CoV-2

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Reposted by Chatel-Chaix Lab
Nature @nature.com · 20/02/2025
Excess mitochondrial fusion is averted by stress-activated regulators, preventing the potentially harmful release of mitochondrial DNA go.nature.com/3EGN5QL
go.nature.com
Putting the brakes on mitochondrial fusion to prevent escape of mitochondrial DNA
Organelle network is regulated to prevent cellular inflammation.
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Reposted by Chatel-Chaix Lab
Canadian Society for Virology @cansocvirol.bsky.social · 01/02/2025
Opportunities for CSV trainees! Apply for the CSV Lab Exchange Program to fund research collaborations or training—deadline: April 1. Details: www.csv-scv.ca/en/lab-excha... Submit your abstract by March 1 to present at the CSV virtual seminar on April 11: forms.gle/zw2YdxQ2kLcc...
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Reposted by Chatel-Chaix Lab
Clive McKimmie @clive-mckimmie.bsky.social · 01/02/2025
We expected it to be bad, but so quickly?
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Reposted by Chatel-Chaix Lab
Holden Thorp @holdenthorp.bsky.social · 31/01/2025
The latest from @science.org on the situation at NIH. @meredithwadman.bsky.social and Jocelyn Kaiser getting all the info they can. www.science.org/content/arti...
science.org
NIH is purging Trump-targeted programs—but is sparing existing grants, so far
Chaos extends to CDC, which is shuttering websites in “data apocalypse”
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Reposted by Chatel-Chaix Lab
Nature @nature.com · 29/01/2025
Despite carrying lethal pathogens, bats rarely develop disease — a phenomenon that has intrigued scientists for decades go.nature.com/4hBWzL0
go.nature.com
Viral tolerance enabled by a bat-specific genomic tweak
Comparative genomics reveals how virus-carrying bats resist disease.
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Reposted by Chatel-Chaix Lab
Julien Pompon @julienpompon.bsky.social · 24/01/2025
preprint advancing #flavivirus transmission understanding: 1. Flavivirus-infected #mosquito saliva always contain sfRNA inside lipide #vesicles. 2. Salivary sfRNA increases transmission by inhibiting MDA5-mediated interferon signalling. www.biorxiv.org/content/10.1...
biorxiv.org
Multiple orthoflaviviruses secrete sfRNA in mosquito saliva to promote transmission by inhibiting MDA5-mediated early interferon response
Numerous orthoflaviviruses transmitted through the bites of different mosquito species infect more than 500 million people annually. Bite-initiated skin infection represents a critical and conserved s...
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Reposted by Chatel-Chaix Lab
Nature @nature.com · 22/01/2025
🇭🇳 Contribute to the community 🇮🇪 Publish papers, but also be publicly visible 🇺🇸 Publication record, impact, and research quality This is how to become a professor where you are go.nature.com/3WpESGE
go.nature.com
Want to become a professor? Here’s how hiring criteria differ by country
Huge analysis identifies regional variations in the criteria that institutions use to move researchers up the ranks.
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Chatel-Chaix Lab @chatel-chaixlab.bsky.social · 22/01/2025
As a first post on Bluesky, I am very proud to share our latest research published in @cp-iscience.bsky.social on how dengue and Zika viruses hijack mitochondrial functions in respiration and apoptosis by altering their contacts with th eendoplasmic reticulum. www.sciencedirect.com/science/arti...
sciencedirect.com
Dengue virus and Zika virus alter endoplasmic reticulum-mitochondria contact sites to regulate respiration and apoptosis
During infection, dengue virus (DENV) and Zika virus (ZIKV), two (ortho)flaviviruses of public health concern worldwide, induce alterations of mitocho…
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