This article presents a method capable of imaging the 3D orientation and lateral positions of fluorescent single-molecule labels in cells. It is applied to the 3D organization of actin filaments withi...

Xu et al. uncovered how duplicated transcription factors DevH and NtcA achieve functional specialization in Anabaena. Unlike NtcA, DevH operates at higher cellular levels with broader regulatory capac...

The Review discusses recent advances in single-molecule orientation and localization microscopy (SMOLM) along with remaining challenges and promises for future developments of the field.

MacDonald et al. show that EGF triggers de-sialylation of plasma membrane glycoproteins like integrins in a mechanism that depends on the Na+/H+ antiporter NHE1 and the neuraminidases Neu1 and Neu3. I...

Single-molecule orientation-localization microscopy: Applications and approaches - Volume 57