Misregulation of chromosome cohesion during female meiosis serves as a reproductive isolating barrier in mice.

"The only constant in life is change." — Heraclitus Genetic conflicts — the good, the bad, and the ugly — shape our lives over time We aim to understand why even the most essential genes and chrom...

Seminar 9 John Werren (University of Rochester): Cooperating on Conflict: Selfish Genetic Elements, Heritable Microbes, and Genetic Conflicts. Bengt O. Bengtsson (Lund University): Decade…

Centromeres reside in rapidly evolving, repeat-rich genomic regions, despite their essential function in chromosome segregation. This study of centromere evolution over short evolutionary timescales i...

Maintaining the dynamic structure of chromatin is critical for regulating the cellular processes that require access to the DNA template, such as DNA …

Background Centromeres depend on chromatin containing the conserved histone H3 variant CENP-A for function and inheritance, while the role of centromeric DNA repeats remains unclear. Retroelements are...