iiinova — where your digital self keeps evolving

Catrin Lutz @catrinlutz.bsky.social · 17/07/2025

Many thanks to everyone who contributed to this work, I'm very happy we can now share the results and this resource with the research community!

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Catrin Lutz @catrinlutz.bsky.social · 17/07/2025

8 years of xenografting breast cancer cell lines and thorough characterisation of the resulting mouse models revealed that context really matters. Breast cancer growth morphology and aggressivess are regulated by auto- and paracrine TGF-beta signalling and strongly depend on transplantation method.

aacrjournals.org

Large-scale Characterization of Orthotopic Cell Line–Derived Xenografts Identifies TGFβ Signaling as a Key Regulator of Breast Cancer Morphology and Aggressiveness

Establishment and investigation of the largest collection of fully characterized breast cancer cell line xenograft models identifies key determinants of tumor morphology and aggressiveness and enables...

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Catrin Lutz @catrinlutz.bsky.social · 17/07/2025

Immensely happy and grateful that our paper got featured in the latest highlights in cancer research. Big thanks to the EACR and all co-authors whose efforts went into this piece of work!

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Reposted by Catrin Lutz

Netherlands Cancer Institute @nkinl.bsky.social · 27/06/2025

Proud! 💙 Our scientific director Thijn Brummelkamp receives the Spinoza Prize, a prize for scientists who belong to the best researchers worldwide. A wonderful recognition for his groundbreaking research. Congrats Thijn! 🎉 @thijnbrummel.bsky.social Full article ➡️ bit.ly/40p4KnK

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Reposted by Catrin Lutz

Sebastian Gregoricchio, Ph.D. @sgregoricchio.bsky.social · 07/05/2025

📢 Are you approaching the epigenetic world? Or you want to know more about ATAC-seq and it's applications? In this case join the @oncodeinstitute.bsky.social workshop that will take place the 19th of September at the @nkinl.bsky.social !! Places are limited to 35!! Subscribe at the following link:

oncodeinstitute.nl

Masterclass: ATAC-seq data analysis and applications | Oncode Institute

By Sebastian Gregoricchio (lab Wilbert Zwart, Netherlands Cancer Institute)

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Catrin Lutz @catrinlutz.bsky.social · 05/04/2025

It's been a real pleasure having this joint ICR NKI retreat again. Many thanks for coming over and the truly inspiring discussions!

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Reposted by Catrin Lutz

Damir Vareslija @damirvareslija.bsky.social · 27/02/2025

Excited to share our review on epigenetic reprogramming in brain metastasis. We review published studies on epigenetic drivers and outline future research directions we’re exploring: www.nature.com/articles/s41... @breastcancernow.bsky.social @stefanprekovic.bsky.social @researchireland.bsky.social

nature.com

The epigenetic landscape of brain metastasis - Oncogene

Oncogene - The epigenetic landscape of brain metastasis

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Catrin Lutz @catrinlutz.bsky.social · 29/01/2025

Looking forward to this read =)

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Catrin Lutz @catrinlutz.bsky.social · 11/01/2025

If you're interested in luminal breast cancer and the advances made in the field, from molecular subtyping to metastatic disease and disease modelling, check out our review, now out in Endocrine-Related Cancer. Thanks @stefanprekovic.bsky.social, @damirvareslija.bsky.social and Hendrik Messal.

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Reposted by Catrin Lutz

Netherlands Cancer Institute @nkinl.bsky.social · 29/11/2024

📢 Applications for the NKI PhD program open from Jan 1 - Feb 28. Join our international research community in Amsterdam, working in cancer biology, AI research & life sciences with leading scientists and top facilities #PhD #CancerResearch More info: bit.ly/3O4bOjq

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Catrin Lutz @catrinlutz.bsky.social · 30/11/2024

And lastly, hot off the press in Oncogene, a great effort by the Prekovic lab @stefanprekovic.bsky.social on describing the roles of STAG2 in cohesin biology and cancer: www.nature.com/articles/s41...

nature.com

Emerging roles of cohesin-STAG2 in cancer - Oncogene

Oncogene - Emerging roles of cohesin-STAG2 in cancer

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Catrin Lutz @catrinlutz.bsky.social · 30/11/2024

Endocrine-Related Cancer gave us the opportunity to write about the complex biology underlying luminal breast cancer and highlight challenges and advances in the field. It was a pleasure writing this with @stefanprekovic.bsky.social and @damirvareslija.bsky.social: pubmed.ncbi.nlm.nih.gov/39498702/

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Catrin Lutz @catrinlutz.bsky.social · 30/11/2024

To start up here I'd like to share some of our recently published reviews:

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