Reposted by Damir VareslijaIrish Association of Cancer Research (IACR) @iacr.bsky.social · 09/01/2026🚨 Call for Late Breaking Abstracts - IACR Annual Conference 2026! 🚨 Deadline: Midnight 16th January 2026 🔗 Submit your abstract: www.iacr.ie/2026-annual-... Ireland’s premier cancer research event exploring innovations in Digital Health, Bioengineering, Liquid Biopsies & Cancer Susceptibility. 011
Damir Vareslija @damirvareslija.bsky.social · 15/08/2025Great way to finish the GRC Hormone-Dependent Cancers Conference by seeing our collaboration with the Wilbert Zwart lab published in PNAS. Glad to have contributed to this work. Read the paper here: www.pnas.org/doi/10.1073/... 020
Damir Vareslija @damirvareslija.bsky.social · 30/04/2025Our review in Cancer Letters is live! 🧠🔬 “Hormonal and Neuronal Interactions Shaping the Brain Metastatic Microenvironment” proposes potential links between sex hormones and neural niche adaptation in brain mets. www.sciencedirect.com/science/arti... #BrainMetastasis #CancerResearch #NeuroOncologysciencedirect.comHormonal and Neuronal Interactions Shaping the Brain Metastatic MicroenvironmentMetastatic progression drives the majority of cancer-related fatalities, and involvement of the central nervous system (CNS) poses especially formidab… 010
Reposted by Damir VareslijaGeorge Sflomos @georgesflomos.bsky.social · 29/03/2025Super nice review on metastasis organo-tropism⬇️ the process where tumor cells preferentially spread to specific distant organs, and represents a critical aspect of cancer biology with profound implications for patient outcomes. #CDH1 www.cell.com/trends/cance...cell.comRegulation of metastatic organotropismMetastasis is responsible for most cancer-related deaths. Different cancers have their own preferential sites of metastases, a phenomenon termed metastatic organotropism. The mechanisms underlying org... 1135
Damir Vareslija @damirvareslija.bsky.social · 27/02/2025Excited to share our review on epigenetic reprogramming in brain metastasis. We review published studies on epigenetic drivers and outline future research directions we’re exploring: www.nature.com/articles/s41... @breastcancernow.bsky.social @stefanprekovic.bsky.social @researchireland.bsky.socialnature.comThe epigenetic landscape of brain metastasis - OncogeneOncogene - The epigenetic landscape of brain metastasis 0113
Reposted by Damir VareslijaIrish Association of Cancer Research (IACR) @iacr.bsky.social · 23/01/2025📢 Last chance to register for the IACR conference, featuring leading experts in AI, drug development, obesity & nutrition, stem cells, and cancer plasticity. Don’t miss out! Stay tuned as we spotlight our fantastic speaker lineup leading up to the conference. 042
Damir Vareslija @damirvareslija.bsky.social · 08/01/2025Sharing the final version of our review on the complex landscape of luminal breast cancer now published with @stefanprekovic.bsky.social, @catrinlutz.bsky.social, and Hendrik. Available here: doi.org/10.1530/ERC-... 031
Damir Vareslija @damirvareslija.bsky.social · 17/12/2024Just Published to close off the year! Our latest work explores the dynamic interplay between ER and HER2 in breast cancer, revealing how treatment drives receptor discordance and impacts clinical outcomes. onlinelibrary.wiley.com/doi/10.1002/...onlinelibrary.wiley.comNeoadjuvant HER2 inhibition induces ESR1 DNA methylation alterations resulting in clinically relevant ER expression changes in breast cancersClick on the article title to read more. 020
Reposted by Damir VareslijaIrish Association of Cancer Research (IACR) @iacr.bsky.social · 16/12/2024Irish Association for Cancer Research (IACR) is joining Bsky. Our mission is to connect researchers and promote cancer research in Ireland. Stay tuned for updates on our initiatives and events, including the upcoming IACR Annual Conference. Let’s advance Irish cancer research! 💡🔬 093
Damir Vareslija @damirvareslija.bsky.social · 12/12/2024Super interesting study. Glucocorticoids promote glioblastoma growth in a time-of-day-dependent manner. Disrupting daily glucocorticoid signaling reduces GBM growth and progression. 041
Damir Vareslija @damirvareslija.bsky.social · 22/11/2024Excited to present our lab's latest research on brain metastasis at BACR conference next Monday/Tuesday/Wednesday and seeing some science friends. 080
Damir Vareslija @damirvareslija.bsky.social · 20/11/2024A Multilineage Screen Identifies Actionable Synthetic Lethal Interactions in Human Cancers www.nature.com/articles/s41...nature.comA multilineage screen identifies actionable synthetic lethal interactions in human cancers - Nature GeneticsA framework combining combinatorial CRISPR knockout in breast, lung and oropharyngeal cancer in vitro models with public data identifies synthetic lethal interactions, such as perturbed KDM5C sensitiz... 040
Reposted by Damir VareslijaSiobhan Gaynor @siobhangaynor.bsky.social · 20/11/2024Delighted to report that the publication or our patient work in Irish Metastatic Breast Cancer patients has gone live. www.sciencedirect.com/science/arti...sciencedirect.comA patient- led survey on information and communication needs of patients with metastatic breast cancer in Ireland and Northern Ireland (CTRIAL-IE 23-05)Although treatment advances have improved survival rates for patients with metastatic breast cancer (MBC), patient expressed needs have not been evalu… 41911
Damir Vareslija @damirvareslija.bsky.social · 17/11/2024Sharing a recently published review I did with Prekovic Lab and Cat Lutz, featured in the Emerging Leaders edition of Endocrine-Related Cancer! Nice opportunity to highlight the complexities of luminal breast cancer erc.bioscientifica.com/view/journal...erc.bioscientifica.com 110
Damir Vareslija @damirvareslija.bsky.social · 16/11/2024Finally caved and joined Bluskye because apparently, academic Twitter is migrating, and I didn’t want to miss the next big thing in posting grants, papers, and my favourite activity sending myself new papers 130