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Carolina Monzó

@carolinamonzo.bsky.social
140 followers 90 following 8 posts

PhD. 🏳️‍🌈 Immunology, aging and bioinformatics enthusiast. @MSCActions postdoc at @i2sysbio.bsky.social @csic.es

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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 21/07/2025
Dont miss any of our #LongTREC communications at #ISMBECCB2025. Download this flyer to make catching all the latest & hottest long-read transcriptomics research simple. @anaconesa.bsky.social
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 14/07/2025
Day 1 of our #SummerSchool : @carolinamonzo.bsky.social , Satrio Wibowo, Mahmud Sami Aydin and @tianyuanliu.bsky.social introducing participants to #LongReads sequencing technologies, how to design #lrRNAseq experiments, library preparation strategies for #lrRNAseq, mapping, QC and more!
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 10/07/2025
We’re kicking off a video series to showcase our network and its mission. 🎥 Watch @anaconesa.bsky.social introducing our project and why raising sustainability awareness in science is so important. @i2sysbio.es @csic.es #LongCyclingForScience 🚴🌎 #LongReadsTranscriptomics 🔬 #Outreach4Science ✍
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 11/07/2025
Continuing our LongTREC video series, we’re excited to feature Fabio Zanarello from @crg.eu in this next episode. #LongReadsTranscriptomics #LongCyclingForScience #SustainableScience
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 12/07/2025
Next in out #LongTREC video series : Nadja Nolte, Doctoral Candidate working with Kristina Gruden and Marko Petek at the National Institute of Biology in Ljubljana, Slovenia. Check the video to learn more about her project! #LongReadsTranscriptomics #Potato #Poliploidy
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 12/07/2025
Next in the #LongTREC video series, we turn the spotlight to Satrio Wibowo, under the supervision of@minomatt.bsky.social at @uniofnottingham.bsky.social, Satrio makes the complex ideas of his project easy to understand with his thoughtful explanation. #LongReadsTranscriptomics #AdaptiveSampling
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 12/07/2025
Next Up in the #LongTREC Series 📽️ : Yalan Bi! Yalan is a LongTREC Doctoral Candidate working with Ralf Herwig at @molgen.mpg.de Yalan shares insights into her research project and her experience as part of the LongTREC network. #LongReadsTranscriptomics #AlternativeSplicing #ProteinInteraction
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 12/07/2025
The LongTREC video series continues with Pablo Angulo Lara, a Doctoral Candidate at @iitalk.bsky.social, where he works under the supervision of Francesco Nicassio. In this video, Pablo talks about his research and its impact. #LongReadsTranscriptomics #aneuploidy #cancer #computationalpipelines
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 13/07/2025
📽️ From 🌞 Valencia: Meet Fabian Jetzinger in the LongTREC Series! Fabian is a Doctoral Candidate at BioBam Bioinformatics, working under the supervision of Stefan Götz, PhD. He is working to make the analysis of long-read RNA sequencing data more user-friendly in #OmicsBox tinyurl.com/nkszjjm5
linkedin.com
📽️ From 🌞 Valencia: Meet Fabian Jetzinger in the LongTREC Series! | LongTREC
📽️ From 🌞 Valencia: Meet Fabian Jetzinger in the LongTREC Series! Fabian is a Doctoral Candidate at BioBam Bioinformatics, working under the supervision of Stefan Götz, PhD. He is working to make the...
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 13/07/2025
📽️ Next in the LongTREC Series: Mahmud Sami Aydin! Sami is a Doctoral Candidate at @stockholm-uni.bsky.social , working under the supervision of @ksahlin.bsky.social .In this video, Sami shares his research and his role in the broader LongTREC collaboration across Europe. #AlgorithmDevelopment
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 13/07/2025
🌊 Exploring the Ocean’s Genetic Secrets! Guided by @jm-aury.bsky.social and France Denoeud, @lafucarmen.bsky.social Doctoral Candidate at Genoscope - Centre National de Séquençage, shares how she's using long-reads on marine samples from the Tara Oceans expedition to explore genetic novelty.
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Reposted by Carolina Monzó
Conesa Lab @conesalab.bsky.social · 03/06/2025
🚀 SQANTI-verse Cards are here! ✨ If you want to get'em all, just follow these steps: 1️⃣ Use one of the SQANTI tools from our Github 2️⃣ Generate amazing data and publish your results 3️⃣ Tag us when you share your publication We’ll send you a card! 8 are already available & more are coming 🌌 #SQANTIverse
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Reposted by Carolina Monzó
I2SysBio @i2sysbio.es · 09/05/2025
Original article: www.nature.com/articles/s41... 🧬🖥️ 👩‍🔬 🧪 The article explains how long-read transcriptomics enables the study of isoform expression, discovery of novel RNAs, gene annotation in understudied species, and differential expression between paternal and maternal chromosomes, etc.
nature.com
Transcriptomics in the era of long-read sequencing - Nature Reviews Genetics
Advances in long-read sequencing are driving the implementation of these technologies for transcriptome profiling. The authors provide a comprehensive guide to long-read RNA sequencing, including expe...
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Reposted by Carolina Monzó
I2SysBio @i2sysbio.es · 09/05/2025
I2SysBio @csic.es researchers Ana Conesa @anaconesa.bsky.social, Carolina Monzó @carolinamonzo.bsky.social and Tianyuan Liu @tianyuanliu.bsky.social published an article on #long-read #transcriptomics in Nature Reviews Genomics. More information: i2sysbio.es/communicatio... ⬇️
i2sysbio.es
I2SysBio explores a new gene sequencing technique to help decipher diseases such as cancer
<h1>&nbsp;</h1> <h3><strong>&nbsp;This revision of the long-read transcriptomic sequencing technology allows a more precise analysis of the RNA molecules present in cells with essential information f...
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Reposted by Carolina Monzó
Arnau Montagud @arnaumontagud.bsky.social · 06/05/2025
📢 Exciting news! We will soon open two PhD positions at @i2sysbio.bsky.social @csic.es, in research projects in collaboration with the @bsc-cns.bsky.social. Both are related to tools to simulate biological tissues. Here’s the description of the open positions. #PhDpositions #PhDOpportunities 👇
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Reposted by Carolina Monzó
LongTREC @longtrec.bsky.social · 07/05/2025
Time is running out to register for our #LongTREC summer school - Consider joining us in Norwich this summer at the @earlhaminst.bsky.social to level up your #LongReads #bioinformatics #transcriptomics skills. Click the link below to learn more. We're looking forward to meeting you all in July!
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Reposted by Carolina Monzó
I2SysBio @i2sysbio.es · 06/05/2025
La nota de prensa de @dicv.csic.es de @csic.es resume los grandes logros de @conesalab.bsky.social en I2SysBio. Ana Conesa @anaconesa.bsky.social y Carolina Monzó @carolinamonzo.bsky.social explican su artículo publicado en Nature Reviews Genetics sobre la transcriptómica de lecturas largas #RNAseq
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Reposted by Carolina Monzó
Delegación CSIC Comunitat Valenciana - Casa de la Ciència @dicv.csic.es · 06/05/2025
El @csic.es analiza una nueva técnica de secuenciación génica que ayudará a descifrar enfermedades como el #cáncer, a conocer mejor la resistencia de las plantas o a examinar virus y bacterias. @anaconesa.bsky.social @carolinamonzo.bsky.social delegacion.comunitatvalenciana.csic.es/el-csic-anal...
Científicas del Instituto de Biología Integrativa de Sistemas (I2SysBio), centro mixto del Consejo Superior de Investigaciones Científicas (CSIC) y la Universitat de València, publican una revisión de la tecnología de secuenciación transcriptómica de lectura larga. Esta tecnología permite analizar con más precisión que los métodos tradicionales, las moléculas de ARN presentes en todas las células y que contienen información genética esencial para la vida. Conocer cómo cambia la expresión génica en los diferentes organismos resulta fundamental para comprender mejor el envejecimiento, las enfermedades neurodegenerativas o el cáncer, por ejemplo. El artículo ha sido publicado en la revista Nature Reviews Genetics.

La transcriptómica engloba el estudio de todas las moléculas de ARN (ácido ribonucleico) presentes en una célula o tejido. Estas son moléculas intermedias entre el ADN y las proteínas. Si bien el ADN contiene la información genética, el ARN es el que permite la síntesis de proteínas y que la información sea comprendida por las células. Esta rama de la ciencia permite entender qué genes están activos en un momento concreto y cuál es su grado de activación en los diferentes organismos, lo que es clave para comprender el origen y desarrollo de muchas enfermedades humanas.
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Reposted by Carolina Monzó
I2SysBio @i2sysbio.es · 16/04/2025
Summary of the work of our researchers @carolinamonzo.bsky.social @anaconesa.bsky.social published recently in Nature Reviews Genetics #bioinformatics #transcriptomics #RNAseq 🧬🖥🧪👩‍🔬
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Reposted by Carolina Monzó
Nature Reviews Genetics @natrevgenet.nature.com · 18/04/2025
FYI: New online! Transcriptomics in the era of long-read sequencing
nature.com
Transcriptomics in the era of long-read sequencing
Nature Reviews Genetics, Published online: 28 March 2025; doi:10.1038/s41576-025-00828-zAdvances in long-read sequencing are driving the implementation of these technologies for transcriptome profiling. The authors provide a comprehensive guide to long-read RNA sequencing, including experimental and computational tools, current applications, challenges and opportunities.
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Carolina Monzó @carolinamonzo.bsky.social · 16/04/2025
Big thanks to RSG-Spain for their beautiful post summarising some highlights of our recent review on #LongReads transcriptomics published on @natrevgenet.nature.com. bit.ly/lrRNA-seq @anaconesa.bsky.social @i2sysbio.bsky.social @longtrec.bsky.social
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Reposted by Carolina Monzó
Genome Research @genomeresearch.bsky.social · 14/04/2025
Part 1 and 2 of the Long-read sequencing Special Issues are now live! tinyurl.com/Genome-Res-LRS
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Ana Conesa @anaconesa.bsky.social · 15/04/2025
Not 1, not 2, but 3 new papers by @conesalab.bsky.social published today in the special issue on long-read sequencing. Find our latest work on SQANTI-reads, genome annotation with lrRNA-seq evidence, and a Perspective in Transcript Divergence. tinyurl.com/GRLong @longtrec.bsky.social
tinyurl.com
Long-read Sequencing Special Collection
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
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Reposted by Carolina Monzó
Miguel 💻🧬 @ahmig.es · 03/04/2025
happy to share our new study! 🧪 while exploring how often #sars-cov-2 "repairs" deletions in BA.1, we found significant genome artifacts in GISAID 🤯 we compared with raw reads from ENA + tested the effects in vitro. turns out, data processing matters a lot 📉 check it out!! doi.org/10.1093/ve/v...
doi.org
Genome data artifacts and functional studies of deletion repair in the BA.1 SARS-CoV-2 spike protein
Abstract. Mutations within the N-terminal domain (NTD) of the spike (S) protein are critical for the emergence of successful SARS-CoV-2 viral lineages. The
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Reposted by Carolina Monzó
Nature Reviews Genetics @natrevgenet.nature.com · 04/04/2025
ICYMI: New online! Transcriptomics in the era of long-read sequencing
nature.com
Transcriptomics in the era of long-read sequencing
Nature Reviews Genetics, Published online: 28 March 2025; doi:10.1038/s41576-025-00828-zAdvances in long-read sequencing are driving the implementation of these technologies for transcriptome profiling. The authors provide a comprehensive guide to long-read RNA sequencing, including experimental and computational tools, current applications, challenges and opportunities.
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Carolina Monzó @carolinamonzo.bsky.social · 02/04/2025
It's so incredibly cool to attend a virtual symposium like #SEH2bioinfo! I also loved giving a talk about #TranscriptDivergency 🫶 Thanks for this cool opportunity #RSGspain
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Carolina Monzó @carolinamonzo.bsky.social · 02/04/2025
Quieres venir a nuestro lab a trabajar conmigo en un proyecto con long-reads transcriptomics? Estás actualmente matriculado en la universidad en el grado o máster? Ofertamos una de las becas de la conexión @bcbhubcsic.bsky.social !!!
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Reposted by Carolina Monzó
Ana Conesa @anaconesa.bsky.social · 28/03/2025
I am so happy to see this manuscript finally out!!! We review and discuss all analysis steps in long reads transcriptomics. Hope the community finds this useful! Hugo thanks to @carolinamonzo.bsky.social and @tianyuanliu.bsky.social for the huge work!!! @longtrec.bsky.social @hitseq.bsky.social
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Carolina Monzó @carolinamonzo.bsky.social · 28/03/2025
mil gràcies!!!
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Carolina Monzó @carolinamonzo.bsky.social · 28/03/2025
Thank youuu!!! 😀
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Reposted by Carolina Monzó
Nature Reviews Genetics @natrevgenet.nature.com · 28/03/2025
Transcriptomics in the era of long-read sequencing go.nature.com/421ZTJm #Review by @carolinamonzo.bsky.social, Tianyuan Liu & @anaconesa.bsky.social @conesalab.bsky.social @i2sysbio.bsky.social
go.nature.com
Transcriptomics in the era of long-read sequencing - Nature Reviews Genetics
Advances in long-read sequencing are driving the implementation of these technologies for transcriptome profiling. The authors provide a comprehensive guide to long-read RNA sequencing, including expe...
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Reposted by Carolina Monzó
Nature Reviews Genetics @natrevgenet.nature.com · 28/03/2025
Free to download for 1 month!
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Reposted by Carolina Monzó
Conesa Lab @conesalab.bsky.social · 28/03/2025
So proud to see @carolinamonzo.bsky.social publishing yet another fantastic paper about transcriptomics. Check out her review that has just been published in Nature Review Genetics ;-) shorturl.at/KeDAf
nature.com
Transcriptomics in the era of long-read sequencing
Nature Reviews Genetics - Advances in long-read sequencing are driving the implementation of these technologies for transcriptome profiling. The authors provide a comprehensive guide to long-read...
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Carolina Monzó @carolinamonzo.bsky.social · 28/03/2025
Big thanks to @i2sysbio.bsky.social, @ec.europa.eu and the Spanish Science Ministry for promoting this work, as well as the reviewers and editor who greatly improved our manuscript!!
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Carolina Monzó @carolinamonzo.bsky.social · 28/03/2025
It's finally out!!!! Our review on long-reads transcriptomics was published in @natrevgenet.bsky.social!! You can have a look at the paper here rdcu.be/efugl! We hope you like it 😀
rdcu.be
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Conesa Lab @conesalab.bsky.social · 25/03/2025
Introducing MOSim! 🚀 A powerful tool created by @carolinamonzo.bsky.social for simulating bulk & single-cell multi-omics data. Perfect for testing methods & exploring complex biological systems. Available now on GitHub & Bioconductor. #MOSim #MultiOmics github.com/ConesaLab/MO...
github.com
GitHub - ConesaLab/MOSim: Bulk and single-cell Multi-Omics ground truth Simulator in R
Bulk and single-cell Multi-Omics ground truth Simulator in R - ConesaLab/MOSim
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Reposted by Carolina Monzó
Maria Dzunkova @dzunkovam.bsky.social · 22/03/2025
My colleagues from I2SysBio @i2sysbio.bsky.social, Ana Conesa @anaconesa.bsky.social and Carolina Monzo @carolinamonzo.bsky.social, published an R package for simulating bulk and #singlecell data from #transcriptomics and #multiomics experiments. Congratulations! 👏 #bioinformatics 🖥🧬 #WomenInSTEM 👩‍🔬
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Reposted by Carolina Monzó
I2SysBio @i2sysbio.es · 22/03/2025
Our researchers Ana Conesa @anaconesa.bsky.social and Carolina Monzo @carolinamonzo.bsky.social published an R package for simulating bulk and #singlecell data from #transcriptomics and #multiomics experiments. Congratulations! 👏 #bioinformatics 🖥🧬 #WomenInSTEM 👩‍🔬 🧪
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Reposted by Carolina Monzó
Ana Conesa @anaconesa.bsky.social · 21/03/2025
Wonder what to do with all these 1000s of novel transcripts found by #long-reads sequencing? Adam Frankish, @carolinamonzo.bsky.social and myself discuss this in our @genomeresearch.bsky.social Perspective. @pacbio.bsky.social @nanoporetech.com @longtrec.bsky.social tinyurl.com/274zkdfz
genome.cshlp.org
Notable challenges posed by long-read sequencing for the study of transcriptional diversity and genome annotation
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
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Reposted by Carolina Monzó
Ana Conesa @anaconesa.bsky.social · 22/03/2025
Proud to see this manuscript by @carolinamonzo.bsky.social from @conesalab.bsky.social in collaboration with #SoniaTarazona´s team. MOSIM simulates any type of (multi)epigenomics data that may regulate gene expression. academic.oup.com/bib/article/... @hitseq.bsky.social @iscb-regsys.bsky.social
academic.oup.com
MOSim: bulk and single-cell multilayer regulatory network simulator
Abstract. As multi-omics sequencing technologies advance, the need for simulation tools capable of generating realistic and diverse (bulk and single-cell)
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Reposted by Carolina Monzó
Ana Conesa @anaconesa.bsky.social · 04/03/2025
Thrilled to see our Perspective on long-read transcriptomics Published in Advance in @genomeresearch.bsky.social, with #AdamFrankish and @carolinamonzo.bsky.social. We discuss the opportunities and challenges of LRS to uncover Transcript Divergence and for Genome Annotation. tinyurl.com/bdeteu4j
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Ana Conesa @anaconesa.bsky.social · 21/02/2025
Proud of Myla Kondratova for the publication of her first first-author paper where she develops a comparative genomics approach for transcription factor binding site prediction in plants, applied to Phaseolus vulgaris, a critical crop for food security @ifas.ufl.edu rdcu.be/eaIQ5
rdcu.be
Profiling conserved transcription factor binding motifs in Phaseolus vulgaris through comparative genomics
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Ana Conesa @anaconesa.bsky.social · 27/01/2025
Precioso reportaje sobre el mural que la pintora Clara Gomez Campos me ha pintado en mi barrio, Benimaclet. disfrutabenimaclet.com/2025/01/27/e...
disfrutabenimaclet.com
El mural que homenajea a la investigadora Ana Conesa en Benimaclet
La investigadora Ana Conesa ya tiene en su barrio, Benimaclet, un mural que la homenajea. Lo ha creado Clara Gómez dentro del proyecto ‘Dones de ciència’.
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Conesa Lab @conesalab.bsky.social · 14/01/2025
Attention people of Bluesky! Today, we had a double celebration. Alejandro has gotten his paper published #ConesaLab 🧑‍🔬 genome.cshlp.org/content/earl...
genome.cshlp.org
Evaluation of strategies for evidence-driven genome annotation using long-read RNA-seq
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
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Carolina Monzó @carolinamonzo.bsky.social · 09/01/2025
#member
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Reposted by Carolina Monzó
I2SysBio @i2sysbio.es · 06/12/2024
New R package developed by @carolinamonzo.bsky.social from @conesalab.bsky.social at I2SysBio for simulation of #Singlecell expression data 🖥🧬🧪 👏👏👏 #bioinformatics #transcriptomics
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Reposted by Carolina Monzó
Conesa Lab @conesalab.bsky.social · 05/12/2024
Today, our amazing postdoc @carolinamonzo.bsky.social gave a seminar on Theoretical and Computational Systems Biology and our classic novel tool MOSim. This R package simulates multi-omics bulk & single-cell gene expression & regulatory mechanisms. Perfect for exploring complex cellular systems! 🔬📊
Clara presenting our latest tool MOSim during the Theoretical and Computational Systems Biology seminar.
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Conesa Lab @conesalab.bsky.social · 04/12/2024
A giant welcome to our newest lab members!! Carlos and Julen to begin their PhD, Pablo for software development within the Oscars project, and great visitors from LongTREC project!! 🎉💃
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Conesa Lab @conesalab.bsky.social · 04/12/2024
🚨 SQANTI3 release alert!! 🚨 v5.3.0 is now LIVE!!! The new release includes better file compatibility, improved parallelization, a wrapper to run QC-filter-resque, and the first release of our newest tool, 👀 SQANTI-reads 🎉! Thanks a lot to the whole team! github.com/ConesaLab/SQ...
github.com
Release SQANTI 5.3.0 · ConesaLab/SQANTI3
This release include some new minor features, such as the inclusion of a Dockerfile of sqanti and a wrapper to execute all SQANTI steps at once. Also enhances compatibility for fastq.gz files in sq...
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Conesa Lab @conesalab.bsky.social · 19/11/2024
Hello world
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