iiinova — where your digital self keeps evolving

Carlo Colantuoni

@carlocolantuoni.bsky.social

1.5K followers 5K following 60 posts

Developing methods & assembling data to explore multi-omic dynamics across cell contexts, in stem cell models & neocortical development, neurodegeneration and neuroinflammation in particular: carlocolantuoni.org

Posts Replies Media

Carlo Colantuoni @carlocolantuoni.bsky.social · 22/09/2026

The recording of today's "Developmental Diversity in a Dish" seminar by Dr. Christopher Baker (from the Jackson Lab in Maine) "Natural genetic variation reveals loci controlling differentiation propensity and lineage specification" is now available at: www.youtube.com/playlist?lis...

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 21/09/2026

Tomorrow! DDD seminar, Sept. 22, 2026 @ 1PM Eastern US: Dr. Christopher Baker (from The Jackson Laboratory in Maine, USA) will share his work on "Natural genetic variation reveals loci controlling differentiation propensity and lineage specification". carlocolantuoni.org

carlocolantuoni.org

HOME | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 17/09/2026

Next week: DDD seminar, Sept. 22, 2026 @ 1PM Eastern US: Dr. Christopher Baker (from The Jackson Laboratory in Maine, USA) will share his work on "Natural genetic variation reveals loci controlling differentiation propensity and lineage specification". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 21/07/2026

The recording of today's "Developmental Diversity in a Dish" seminar by Dr. Lifan Liang "Single-cell multiomics of neuron activation reveals context-specific genetics of brain disorders" is now available online at: www.youtube.com/watch?v=Tc71...

Lifan Liang - Multiomics of neuron activation reveals context-specific genetics of brain disorders

YouTube video by Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 20/07/2026

Tomorrow: DDD seminar, July 21, 2026 @ 1PM Eastern US: Dr. Lifan Liang (from Jubao Duan's group in Chicago) will share his recent work on "Single-cell multiomics of neuron activation reveals context-specific genetics of brain disorders". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 15/07/2026

Next week: DDD seminar, July 21, 2026 @ 1PM Eastern US: Dr. Lifan Liang (from Jubao Duan's group in Chicago) will share his recent work on "Single-cell multiomics of neuron activation reveals context-specific genetics of brain disorders". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 26/05/2026

Dr. Pau Puigdevall Costa's @paupuigdevall.bsky.social (from Helena Kilpinen's @hkilpinen.bsky.social) DDD talk from earlier today on midbrain dopaminergic neuron development & modeling is online at: www.youtube.com/playlist?lis.... More info on the DDD seminar series at: carlocolantuoni.org/seminar.

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 25/05/2026

Tomorrow: DDD seminar, May 26, 2026 @ 1PM Eastern US: Dr. Pau Puigdevall Costa @paupuigdevall.bsky.social (from Helena Kilpinen's @hkilpinen.bsky.social group) will share his recent work on "An in vivo and in vitro spatiotemporal profile of human midbrain development". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 14/05/2026

In 2 weeks: DDD seminar, May 26, 2026 @ 1PM Eastern US: Dr. Pau Puigdevall Costa @paupuigdevall.bsky.social (from Helena Kilpinen's @hkilpinen.bsky.social group) will share his recent work on "An in vivo and in vitro spatiotemporal profile of human midbrain development". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 01/05/2026

Ariana Marquez Gonzalez's DDD talk (from steinlab.bsky.social) on "A human cortical organoid framework for exploring gene by environment interactions in ASD" is now online at: www.youtube.com/playlist?lis... [carlocolantuoni.org/seminar]

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 30/04/2026

Tomorrow: DDD seminar May 1, 2026 @ 11AM Eastern US (NOTE NEW TIME &DATE): Ariana Berenice Marquez Gonzalez (from steinlab.bsky.social at UNC) will share her recent work on "A human cortical organoid framework for exploring gene by environment interactions in ASD". carlocolantuoni.org/seminar

steinlab.bsky.social

Jason Stein (@steinlab.bsky.social)

Associate to the professor, UNC Chapel Hill Dept of Genetics and UNC Neuroscience Center, studying genetic effects on brains, steinlab.org

Carlo Colantuoni @carlocolantuoni.bsky.social · 26/04/2026

Next Friday: DDD seminar May 1, 2026 @ 11AM Eastern US (NOTE NEW TIME &DATE): Ariana Berenice Marquez Gonzalez (from steinlab.bsky.social at UNC) will share her recent work on "A human cortical organoid framework for exploring gene by environment interactions in ASD". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 25/03/2026

Today in Nature Neuroscience we have published our exploration of neocortical development leveraging 100's of public datasets. You can interrogate the entire compendium of data at nemoanalytics.org/landing/neoc... and read the paper at www.nature.com/articles/s41....

This link will take you to a page that’s not on LinkedIn

Carlo Colantuoni @carlocolantuoni.bsky.social · 17/03/2026

Dr. Andrew Basset's talk on AD risk gene CRISPR screens in neurons and astrocytes is now online at: www.youtube.com/playlist?lis.... The links to public AD data and related gene signatures that we looked at can be found here: nemoanalytics.org/landing/neur... carlocolantuoni.org/seminar

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 16/03/2026

Tomorrow: DDD seminar, Mar. 17, 2026 @ 11AM Eastern US (NOTE EARLIER TIME TO ACCOMODATE SPEAKER IN THE UK): Dr. Andrew Basset (Wellcome Sanger Inst., Cambridge, UK) will share his recent work on "A CRISPR way to understand neurodegeneration". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 17/02/2026

Dr. Annerieke Sierksma's DDD talk detailing individual human microglial responses to Abeta pathology in mouse AD models is now online at : www.youtube.com/playlist?lis... (carlocolantuoni.org/seminar)

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 17/02/2026

In 1 hour: DDD seminar, Feb. 17, 2026 @ 1PM Eastern US: Dr. Annerieke Sierksma (in Dr. Bart De Strooper's group at KU Leuven) will share her recent work on "Polygenic risk for Alzheimer’s disease shapes microglial inflammatory and antigen-presentation programs in vivo". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 11/02/2026

NEXT TUE: DDD seminar, Feb. 17, 2026 @ 1PM Eastern US: Dr. Annerieke Sierksma (in Dr. Bart De Strooper's group at KU Leuven) will share her recent work on "Polygenic risk for Alzheimer’s disease shapes microglial inflammatory and antigen-presentation programs in vivo". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 26/01/2026

Tomorrow: DDD seminar, Jan. 27, 2025 @ 1PM Eastern US: Nadezhda Azbukina @nazbukina.bsky.social (from Dr. Barbara Treutlein's group) will speak on "A systematic study of morphogen patterning and its reproducibility in human neural organoids". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 23/01/2026

NEXT TUE: DDD seminar, Jan. 27, 2025 @ 1PM Eastern US: Nadezhda Azbukina @nazbukina.bsky.social (from Dr. Barbara Treutlein's group) will speak on "A systematic study of morphogen patterning and its reproducibility in human neural organoids". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 16/12/2025

Tommy Vierbuchen @tvierbuchen.bsky.social shared his work with us today: "A pluripotent stem cell platform for in vitro systems genetics studies of mouse brain development". see the recording at: www.youtube.com/playlist?lis... (more info at www.carlocolantuoni.org/seminar)

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 09/12/2025

NEXT TUE: DDD seminar, Dec. 16, 2025 @ 1PM Eastern US: Dr. Tommy Vierbuchen @tvierbuchen.bsky.social will share his recent work on on cell villages using outbred mice: "A pluripotent stem cell platform for in vitro systems genetics studies of mouse brain development". carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 18/11/2025

Today's DDD seminar by Dr. Michael Wells @mfwells.bsky.social, "Cell villages and Dirichlet modeling map human cell fitness genetics", is now available online at www.youtube.com/playlist?lis... (more seminar info at: www.carlocolantuoni.org/seminar)

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 18/11/2025

TODAY: DDD seminar, Nov. 18, 2025 @ 1PM Eastern US: Continuing our focus on approaches to the study of many pluripotent stem cell lines, Dr. Michael Wells @mfwells.bsky.social will share his most recent work on "cell villages". seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 11/11/2025

NEXT TUE: DDD seminar, Nov. 18, 2025 @ 1PM Eastern US: Continuing our focus on approaches to the study of many pluripotent stem cell lines, Dr. Michael Wells @mfwells.bsky.social will share his recent work on "cell villages". seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 14/10/2025

Today's DDD seminar by Dr. Alex Pollen exploring interspecies midbrain dopaminergic organoids is now available at: www.youtube.com/playlist?lis...

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 14/10/2025

TODAY: DDD seminar, Oct. 14, 2025 @ 1PM Eastern US: Continuing our focus on variation in early fate decisions and CNS regionalization, Dr. Alex Pollen will share his recent work on cross-species midbrain dopaminergic organoids. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 08/10/2025

NEXT TUE: DDD seminar, Oct. 14, 2025 @ 1PM Eastern US: Continuing our focus on variation in early fate decisions and CNS regionalization, Dr. Alex Pollen will share his recent work on cross-species midbrain dopaminergic organoids. seminar info: carlocolantuoni.org/seminar -repost to spread the word

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 16/09/2025

Today: DDD seminar, Sept. 16, 2025 @ 1PM Eastern US: Continuing our focus on early fate decisions and CNS regionalization, today Sept. 16th at 1PM Eastern US time, Gaurav Rathore (Angete Kirkeby's group) will share his recent work. seminar info: carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 08/09/2025

NEXT TUE: DDD seminar, Sept. 16, 2025 @ 1PM Eastern US: Continuing our focus on early fate decisions and CNS regionalization, next Tuesday Sept. 16th at 1PM Eastern US time, Gaurav Rathore (from Angete Kirkeby's group) will share his recent work. seminar info: carlocolantuoni.org/seminar.

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 19/08/2025

Today: DDD seminar, Aug. 19, 2025 @ 1PM East US: Live group exploration of transcriptomic datasets from previous seminars (from groups of @sergiuppasca.bsky.social, Barbara Treutlein, & @floravaccarino.bsky.social) on modeling CNS regionalization in stem cell systems: carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Reposted by Carlo Colantuoni

Gabriel Santpere @santperelab.bsky.social · 10/07/2025

Excited to share our latest work, spearheaded by my brilliant student Xoel Mato and co-led by Nicola Micali. After years of sweat, intense weekly meetings, and meticulous discussion of every panel, we learned a lot from each other. Grateful for the journey! @researchmar.bsky.social rdcu.be/evCaU

Early developmental origins of cortical disorders modeled in human neural stem cells

Nature Communications - The implications of early telencephalic development in cortical disorders remain elusive. Here, the authors define risk gene dynamics and perturbation effects in neural stem...

Reposted by Carlo Colantuoni

Suel-Kee Kim @suelkeekim.bsky.social · 10/07/2025

Excited to share our latest work, Mato-Blanco et al., nature.com/articles/s41.... Thanks to the incredible collaboration with Nicola Micali, Rakic lab, Sestan lab, Vaccarino lab @yaleneuro.bsky.social @santperelab.bsky.social @carlocolantuoni.bsky.social

Early developmental origins of cortical disorders modeled in human neural stem cells - Nature Communications

The implications of early telencephalic development in cortical disorders remain elusive. Here, the authors define risk gene dynamics and perturbation effects in neural stem cells, revealing vulnerabi...

Carlo Colantuoni @carlocolantuoni.bsky.social · 08/07/2025

The recording of today's DDD seminar by Dr. Alessandro Vitriolo @alessandrovitriolo.bsky.social (Lab of Dr. Giuseppe Testa) “Regulatory logic of human cortex evolution by combinatorial perturbations” is now online at: www.youtube.com/playlist?lis...

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 07/07/2025

TOMORROW: DDD seminar, July 8, 2025 @ 1PM Eastern US: Dr. Alessandro Vitriolo @alessandrovitriolo.bsky.social (Lab of Dr. Giuseppe Testa) “Regulatory logic of human cortex evolution by combinatorial perturbations”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 01/07/2025

NEXT TUE: DDD seminar, July 8, 2025 @ 1PM Eastern US: Dr. Alessandro Vitriolo @alessandrovitriolo.bsky.social‬ (Lab of Dr. Giuseppe Testa) “Regulatory logic of human cortex evolution by combinatorial perturbations”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 10/06/2025

The recording of today's DDD seminar by Magdalena Sutcliffe (lab of Dr. Madeline Lancaster @lancasterlab.bsky.social ) “Epigenetic restoration of differentiation competency via reversal of epiblast regionalisation” is now online at: www.youtube.com/playlist?lis... (www.carlocolantuoni.org/seminar)

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 09/06/2025

Tomorrow: DDD seminar, June 10, 2025 @ 1PM Eastern US: Dr. Magdalena Sutcliffe (lab of Dr. M Lancaster @lancasterlab.bsky.social) “Epigenetic restoration of differentiation competency via reversal of epiblast regionalisation”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 04/06/2025

NEXT TUE: DDD seminar, June 10, 2025 @ 1PM Eastern US: Dr. Magdalena Sutcliffe (lab of Dr. M Lancaster @lancasterlab.bsky.social) “Epigenetic restoration of differentiation competency via reversal of epiblast regionalisation”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 06/05/2025

The recording of today's DDD seminar by Dr. Ron McKay “Origin and consequences of genetically distinct behaviors in human neural stem cells” is now online at: www.youtube.com/playlist?lis...

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 05/05/2025

TOMORROW: DDD seminar, May 6, 2025 @ 1PM Eastern US: Dr. Ron McKay “Origin and consequences of genetically distinct behaviors in human neural stem cells”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 29/04/2025

NEXT TUE: DDD seminar, May 6, 2025 @ 1PM Eastern US: Dr. Ron McKay “Origin and consequences of genetically distinct behaviors in human neural stem cells”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 01/04/2025

The recording of today's DDD seminar by Dr. Jason Stein (UNC) steinlab.bsky.social “Modeling genetics altering human cortical structure” is now online at: www.youtube.com/playlist?lis...

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 31/03/2025

TOMORROW: DDD seminar, Apr. 1, 2025 @ 1PM Eastern US: Dr. Jason Stein steinlab.bsky.social “Modeling genetics altering human cortical structure”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

steinlab.bsky.social

Jason Stein (@steinlab.bsky.social)

Associate to the professor, UNC Chapel Hill Dept of Genetics and UNC Neuroscience Center, studying genetic effects on brains, steinlab.org

000

Carlo Colantuoni @carlocolantuoni.bsky.social · 26/03/2025

NEXT TUE: DDD seminar, Apr. 1, 2025 @ 1PM Eastern US: Dr. Jason Stein steinlab.bsky.social “Modeling genetics altering human cortical structure”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 11/03/2025

TODAY: DDD seminar, Mar. 11, 2025 @ 1PM Eastern US: Dr. Martine Therrien (UC Davis) “Systematic interrogation of free fatty acid toxicity in neurodegenerative diseases”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 05/03/2025

NEXT TUE: DDD seminar, Mar. 11, 2025 @ 1PM Eastern US: Dr. Martine Therrien (UC Davis) “Systematic interrogation of free fatty acid toxicity in neurodegenerative diseases”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 19/02/2025

The recording of today's DDD seminar by Dr. @kristenbrennand.bsky.social (Yale University) is now online at: www.youtube.com/playlist?lis...

Developmental Diversity in a Dish Seminar Series - YouTube

A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...

Carlo Colantuoni @carlocolantuoni.bsky.social · 18/02/2025

TOMORROW: DDD seminar, Feb. 18, 2025 @ 1PM Eastern US: Dr. @kristenbrennand.bsky.social (Yale University) “Using Stem Cells to Explore Gene x Environment Interactions Underlying Brain Disease”. seminar info: carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni

Carlo Colantuoni @carlocolantuoni.bsky.social · 11/02/2025

NEXT TUE: DDD seminar, Feb. 18, 2025 @ 1PM Eastern US: Dr. @kristenbrennand.bsky.social - “Using Stem Cells to Explore Gene x Environment Interactions Underlying Brain Disease”. seminar info: carlocolantuoni.org/seminar

carlocolantuoni.org

SeminarPage | Carlo Colantuoni