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Carling

@carlingsmith.bsky.social
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PhD candidate at UBC - Sex differences in Diabetes - Rideout Lab - she/they ✨ My views are my own ✨

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CIRTN-R2FIC @cirtn.bsky.social · 22/09/2026
The final recap of CIRTN Summer 2026 publications: August🌻! Here are works from the labs of Drs. Devlin, Dhavantari, Hill, Korbutt, Pepper, Lim, Prentki, Rabasa-Lhoret and Shapiro.
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CIRTN-R2FIC @cirtn.bsky.social · 08/09/2026
(🧵14/17) June 2026: From Drs Rideout and Johnson: “Sex Differences in ER Stress Pathways Are a Key Determinant of β-Cell Proliferation and Resilience” PMID: 42330305 diabetesjournals.org/diabetes/art...
diabetesjournals.org
Sex Differences in ER Stress Pathways Are a Key Determinant of β-Cell Proliferation and Resilience
As the sole source of circulating insulin in the body, β-cells synthesize up to ∼5,000 insulin molecules per second (1). This enormous burden on β-cell pro
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CIRTN-R2FIC @cirtn.bsky.social · 08/09/2026
(🧵1/17) CIRTN labs continued to publish throughout the Summer. We will recap the works three parts. In June, there have been publications from Drs. Ferdaoussi, Gaisano, Hoesli, Kopp, Verchere, Levings, Lynn, P. MacDonald, Nostro, Paraskevas, Rabasa-Lhoret, Riddell, Rideout, Johnson and Rutter.
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Nature @nature.com · 14/07/2026
This PhD student loves research, but not the realities of experimenting on animals. What are their options? go.nature.com/4phUw3U
go.nature.com
My research on mice is causing me stress. How can I become more resilient?
A PhD student loves research, but not the realities of experimenting on animals. What are their options?
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Carl T. Bergstrom @carlbergstrom.com · 12/07/2026
My coauthor Jay Falk's postdoctoral fellowship was terminated by the Trump administration for documenting the hummingbird example in this paper.
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PowerPoint
Operational biological sex definitions applied to hummingbirds (Bleiweiss 1992; Bleiweiss 1999; Bleiweiss 2001; Diamant et al. 2021; Falk et al. 2022; Falk et al. 2021) where sex is operationally defined by binary plumage phenotypes in the field. Each row depicts a wild individual hummingbird with morphological traits (beak length, plumage coloration), behavioural traits (territoriality) and their unobserved gamete type. This example illustrates how the same individual can be operationally defined as one sex in the field (based on external phenotypes) but classified as a different sex based on their gametes (which cannot be easily observed in the field), highlighting how definitional choices shape scientific reporting of sex.
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Nature Metabolism @natmetabolism.nature.com · 22/06/2026
RESEARCH | @alquierthierry.bsky.social @ejrideout.bsky.social et al.: Neuronal lipid droplet formation mediates energy homeostasis in a sex-specific manner in Drosophila and mice 🧪
dlvr.it
Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis - Nature Metabolism
In vivo regulation of neuronal lipid droplet formation mediates whole-body energy homeostasis in a sex-specific manner in Drosophila and mice.
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Mark Huising @huisinglab.bsky.social · 21/06/2026
Full open access link here: rdcu.be/fptyS
rdcu.be
Somatostatin receptors shape insulin and glucagon output within the pancreatic islet in mice through direct and paracrine effects
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The Washington Post @washingtonpost.com · 16/05/2026
PCOS is one of the most common hormonal disorders, affecting about 170 million women worldwide. Now, it’s officially getting a rebrand — and women living with the condition and clinicians are hopeful it will help more people get the care they need.
washingtonpost.com
Women with this condition are often misdiagnosed. Its new name could help.
The PCOS name change to PMOS aims to reflect the full scope of the condition — and finally unlock the care women have been seeking for years.
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CIRTN-R2FIC @cirtn.bsky.social · 01/05/2026
(🧵 1/22) Many publications from the CIRTN labs this Spring 🌷! Works are from Drs Bruin, MacDonald, Johnson, Mulvihill, Chen, Verchere, Kolic, Huang, Hull-Meichle, Kin, Shapiro, Korbutt, Pepper, P. MacDonald, T. MacDonald, Rideout, Riddell, Rutter, Rabasa-Lhoret and Prentice.
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Nature @nature.com · 22/04/2026
Researchers are gaining a new appreciation for the genes on the X and Y chromosomes and how they shape responses to drugs, disease susceptibility, and more go.nature.com/4cqnQ3p
go.nature.com
The misunderstood sex chromosome: how X affects your health
Researchers are gaining a new appreciation for the genes on the X and Y chromosomes and how they shape sex differences in health and disease susceptibility.
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Robert Screaton @roblab.bsky.social · 18/04/2026
link.springer.com/article/10.1... New article from the group on the effects of aging and sex in beta cell glucose sensing - ROMO1 and complex II! Thanks to funders @diabetescanada.bsky.social and CIHR.
link.springer.com
ROMO1 and mitochondrial complex II/SDH are required for spare respiratory capacity and glucose homeostasis in mice - Diabetologia
Aims/hypothesis Reactive oxygen species modulator 1 (ROMO1) is a highly conserved inner mitochondrial membrane protein that senses reactive oxygen species and regulates mitochondrial dynamics. ROMO1 i...
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alquierthierry.bsky.social @alquierthierry.bsky.social · 14/04/2026
1/ Excited & proud to share the results of an exceptional collaboration with @ejrideout.bsky.social led by R. Manceau & D. Majeur @crchum.bsky.social & @umontreal-en.bsky.social, demonstrating the conserved role of lipid droplet function in hunger-activated neurons. www.nature.com/articles/s42...
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Nature Metabolism @natmetabolism.nature.com · 14/04/2026
dlvr.it
Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis
Nature Metabolism, Published online: 14 April 2026; doi:10.1038/s42255-026-01508-wIn vivo regulation of neuronal lipid droplet formation mediates whole-body energy homeostasis in a sex-specific manner in Drosophila and mice.
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Mariko Bennett @nachoriko.bsky.social · 24/03/2026
I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.
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Madeleine Bonsma-Fisher, PhD @mbonsma.bsky.social · 05/03/2026
Every sleep researcher ever, all the time: permanent Standard Time is unquestionably better for our health Governments: we're switching to permanent daylight time! Anyway, sign this petition for permanent Standard time: www.ourcommons.ca/petitions/en...
ourcommons.ca
Petition e-7155 - Petitions
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Carolina Tropini (TropiniLab@UBC) @ctropini.bsky.social · 13/02/2026
CIHR funding rate: 13.6%. Early 2000s: 30%+. Canada’s new $1.7B Impact+ program recruits talent — but without increased Tri-Council base funding, we risk further strain on an already stretched system. We’re calling for $1B over 5 years. Support here: tinyurl.com/33c5av46
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CIRTN-R2FIC @cirtn.bsky.social · 02/02/2026
(🧵1/23) First month of 2026: complete✅! Many papers coming from CIRTN scientists, including works from the labs of Drs Bruin, Lynn, Estall, Ferdaoussi, Fullerton, Hull-Meichle, Pepper, Korbutt, Levings, Lim, Mulvihill, Rabasa-Lhoret, Riddell, Rutter, Tsai, Woo and Verchere! 📝
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Amy Diehl, Ph.D. @amydiehl.bsky.social · 31/01/2026
Many routine procedures were designed for male anatomy & are uncomfortable or take longer in women. Colonoscopy. Urinary cauterization. Spinal procedures. Airway management. Venous cannulation. Difficulty is often blamed on anxiety, tension, low pain tolerance. theconversation.com/routine-medi...
theconversation.com
Routine medical procedures can feel harder for women – here’s why
When medical procedures are designed around male anatomy, women often pay the price – in pain, difficulty and dismissal.
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CIRTN-R2FIC @cirtn.bsky.social · 25/11/2025
CIRTN-R2FIC is currently running in Toronto its 4th Annual Meeting. During this meeting we have launched our mini interview series called "Islets in a Pod" ! Our first interview is with Dr. Patrick MacDonald from the University of Alberta. youtu.be/UlHn_1Fz3ck?...
youtu.be
#1 Islets in a Pod with Dr. Patrick MacDonald
YouTube video by CIRTN-R2FIC
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CIRTN-R2FIC @cirtn.bsky.social · 12/09/2025
Hello! Welcome to the CIRTN-R2FIC BlueSky account! Our group focuses on researching pancreatic islet biology and pathology related to islets such as type 1 and type 2 diabetes. Here you will find bi-weekly updates from the scientists from across Canada that make up CIRTN-R2FIC.
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Dylan MacKay @dylanmackayphd.bsky.social · 19/04/2025
Timely given the 1500+ researchers who have signed this open letter to the federal party leaders calling for a historic investment in Canadian research sovereignty! docs.google.com/document/d/1...
docs.google.com
National Letter
Open Letter from Canadian Researchers to the Federal party leaders Click here to sign this letter See who has signed - version française se trouve à page 3 - Dear Party Leaders We, the undersigne...
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Daniel Drucker @danieljdrucker.bsky.social · 19/04/2025
Clinical pearls #T2D Hypercortisolism was associated with hyperglycemia in approximately one-quarter of individuals with inadequately controlled type 2 #diabetes despite multiple medications diabetesjournals.org/care/article... ada.silverchair-cdn.com/ada/content_...
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Krista Lamb @kristalamb.bsky.social · 08/03/2025
Finally made a Canadian Diabetes Research starter pack! Join our fun community and follow these talented colleagues. 🧪https://go.bsky.app/PFHwQS
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Jon Cooper @joncooper-us.bsky.social · 28/02/2025
Pass it on. #StandWithUkraine
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Nature @nature.com · 20/02/2025
In a study involving >500 people, the AI identified a range of infections and health conditions, as well as whether participants had received a flu vaccine. go.nature.com/4gPUpGT
go.nature.com
AI tool diagnoses diabetes, HIV and COVID from a blood sample
‘One-shot’ approach that uses machine learning to screen immune cells could help to detect conditions with overlapping symptoms.
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Nature @nature.com · 20/02/2025
Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget. go.nature.com/4gM6oW4
go.nature.com
Revealed: NIH research grants still frozen despite lawsuits challenging Trump order
The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.
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Susanne Ahmari @ahmarilab.bsky.social · 14/02/2025
🚨Amidst all the uncertainty at NIH Welcome Leap just launched an important new $50M program in Women’s Health👩🏻‍🔬🧠 CARE focuses on the link between Alzheimer’s and perimenopausal hormonal changes wellcomeleap.org/care/ Note: full indirects! Please share widely to support women’s health 🙏🏼
wellcomeleap.org
CARE Program Details | Wellcome Leap: Unconventional Projects. Funded at Scale.
NEW $50M Program in Women's Health care Cutting Alzheimer's Risk through EndocrinologyWe are pleased to announce the selected performers.Sabine Vollstädt-Klein, Central Institute of Mental Health ...
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Jim Johnson 🇨🇦 @jimjohnsonsci.bsky.social · 13/02/2025
Alyssa Weinrauch who has 3 PDF mentors, Dan Lucian, Francis Lynn and me, with her presentation on lipids in stem cells and human islets.
Alyssa
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Jim Johnson 🇨🇦 @jimjohnsonsci.bsky.social · 12/02/2025
#abc2025 is on!!
Group picture
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Jim Johnson 🇨🇦 @jimjohnsonsci.bsky.social · 12/02/2025
Sing-Young Chen from the Rideout @ejrideout.bsky.social and Johnson labs giving a beautiful short talk on sex differences in islet biology #abc2025
Sing Young
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Jim Johnson 🇨🇦 @jimjohnsonsci.bsky.social · 12/02/2025
Carling Smith from @ejrideout.bsky.social lab continuing the discussion of sex differences in diabetes. (It’s not lost on the audience here that these talks can easily happen in Canada and the rest of the civilized world and eventually it will help our populations be healthier :)
Sex differences in diabetes
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