Sign in

Carolina Tropini (TropiniLab@UBC)

@ctropini.bsky.social
260 followers 79 following 6 posts

Assistant Professor at the University of British Columbia studying the gut microbiota and abiotic environment in health and disease. tropini.microbiology.ubc.ca

PostsRepliesMedia
Carolina Tropini (TropiniLab@UBC) @ctropini.bsky.social · 13/02/2026
CIHR funding rate: 13.6%. Early 2000s: 30%+. Canada’s new $1.7B Impact+ program recruits talent — but without increased Tri-Council base funding, we risk further strain on an already stretched system. We’re calling for $1B over 5 years. Support here: tinyurl.com/33c5av46
34731
Carolina Tropini (TropiniLab@UBC) @ctropini.bsky.social · 28/01/2026
Excited to share our latest publication, led by Dr. Ellie McCallum and Juan Burckhardt! bit.ly/4kfzQaf You can access the article for free here: authors.elsevier.com/a/1mWb4L7PXu... And more information is available on the updated preprint: www.biorxiv.org/content/10.1...
bit.ly
Glowing bacterial sensors detect gut illness in mice before symptoms emerge
UBC researchers have engineered gut bacteria that dim their fluorescent glow in the presence of illness.
32411
Carolina Tropini (TropiniLab@UBC) @ctropini.bsky.social · 20/03/2025
Sharing exciting work led by PhD students McCallum and Burckhardt! We created a new series of syn bio tools in Bacteroides to create non-invasive, real time and sensitive in vivo gut biosensors. www.biorxiv.org/content/10.1...
biorxiv.org
Expanding the Bacteroides synthetic biology toolkit to develop an in vivo intestinal malabsorption biosensor.
The human gut is a highly dynamic physical environment where perturbations - including factors such as acidification, oxygenation, and particle concentration (osmolality) - can influence microbiota co...
0113
Carolina Tropini (TropiniLab@UBC) @ctropini.bsky.social · 19/03/2025
Excited to share our latest preprint led by Dr. Hunter! We show that osmotic shifts, common in the gut, alter T4 phage-E. coli evolution. High osmolality promotes fitness but selects for mucoid, weakly phage-resistant E. coli, with implications for phage therapy! biorxiv.org/content/10.1...
biorxiv.org
Osmotic conditions shape fitness gains and resistance mechanisms during E. coli and T4 phage co-evolution
Bacteriophages, or phages, are viruses that infect bacteria and offer a promising approach to combating antimicrobial resistance in the gut by selectively targeting harmful bacteria while preserving t...
0166
Carolina Tropini (TropiniLab@UBC) @ctropini.bsky.social · 23/02/2025
Excited to share our latest publication by Adel Yavarinasab et al!
042
Carolina Tropini (TropiniLab@UBC) @ctropini.bsky.social · 28/12/2024
Very excited to share a new paper in collaboration with the Ciernia lab! We show that early-life inflammation alters sex hormones and mating behavior in mice, alongside shifts in hormone-modifying microbiota members! Great work by Olivia Sullivan, Claire Sie and many others! doi.org/10.1016/j.bb...
doi.org
Redirecting
000