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Chris Jackson

@cajackson.org
478 followers 2K following 362 posts

Systems biology

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Reposted by Chris Jackson
Ákos T Kovács @evolvedbiofilm.bsky.social · 10h
The phenotypic landscape of the model firmicute Bacillus subtilis PNAS from Carol A. Gross www.pnas.org/doi/10.1073/...
pnas.org
The phenotypic landscape of the model firmicute Bacillus subtilis | PNAS
Firmicutes are gram-positive bacteria with important roles in human health, disease, and industry. However, more than a quarter of genes in the mod...
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Chris Jackson @cajackson.org · 17h
between this and the banned words list anyone who can write an application that gets through the filters is getting funded 🤷
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Chris Jackson @cajackson.org · 17h
those poor kids applying for the grfp in three weeks are in for it
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Chris Jackson @cajackson.org · 29/09/2026
empty the salt domes so they can refill it with a strategic tallow reserve
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Chris Jackson @cajackson.org · 28/09/2026
are they good old Ontario girls or soft European pansies
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Chris Jackson @cajackson.org · 26/09/2026
Dunno if it's a comms problem, seems like the goal is to jam through as much as possible while they have cover from Trump
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Chris Jackson @cajackson.org · 26/09/2026
Ah my favorite, formal in person interview and you get an form email two years later when HR finally closes the job posting
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Reposted by Chris Jackson
ProPublica @propublica.org · 26/09/2026
Hey, ProPublica reporter Jake Pearson here. I’m taking over the account to tell you about my new story. For months, I posed as a problem gambler on DraftKings to test the company's "responsible gaming" safeguards. Spoiler alert: They made me a VIP — and I lost $10K. Here's how it all went down. 🧵
Selfie taken by ProPublica reporter Jake Pearson, a man wearing a backwards baseball cap and an orange T-shirt.
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Reposted by Chris Jackson
John Stott @jpsastro.bsky.social · 24/09/2026
Had a UKRI funded grant proposal rejected at the "AI triage stage". "This AI-based triage was used only to identify approximately 50% of the strongest proposals to take forward to full human review." 🧪 #academicsky
I am writing to let you know that, unfortunately, your application was not successful.

Review process

As part of the initial triage of the 179 proposals submitted to this call, each was assessed using an AI-based review. Every proposal was read independently by several different AI models against the same seven criteria used to shape this call (including cyber security relevance, research quality and novelty, importance of the problem addressed, feasibility of the project plan, likely outputs and impact, value for money, and responsible research practice), with each model asked to give a score and a written justification with supporting quotations from the text. To guard against any one model's idiosyncrasies, we also ran a second, independent process in which different AI models debated the merits and weaknesses of each proposal before reaching a judgement, again against the same criteria. Scores from both processes were combined to produce an overall ranking. 

This AI-based triage was used only to identify approximately 50% of the strongest proposals to take forward to full human review.  Projects selected for funding were drawn from those that progressed to the full human review stage. We recognise that AI-assisted assessment is a new and evolving part of the review process, and we are continuing to evaluate how well it aligns with the judgements of human reviewers on this call. We will soon produce a document detailing our method, so that others can build upon it and improve it.

Feedback on your application

Your application was not selected to progress beyond the AI triage stage.  To provide transparency on the outcome of this assessment, we are sharing below the scores (out of 5) from each of the two AI review processes described above, together with the mean score across the two processes.
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Chris Jackson @cajackson.org · 24/09/2026
Do grayscale images before ML even exist for this kind of superresolution microscopy? If they were using one of the subcelluar things as evidence for something I'd be more worried, but they aren't
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Chris Jackson @cajackson.org · 24/09/2026
Ehh I'm reluctant to call "we threw color on this but just to make it pretty, not for science" image manipulation Lotta colorized or optical stained DIC images that are pretty much the same thing
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Chris Jackson @cajackson.org · 23/09/2026
Yeah that's why I say 'looks like', all the splitters are oriented wrong I'm pretty sure I know what their physical setup is based on the diagram; the next step is probably some insane superresolution blackbox ML signal processor, that's the voodoo part
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Chris Jackson @cajackson.org · 23/09/2026
That part looks like a standard confocal setup Don't ask me about the superresolution parts, every time it sounds like voodoo to me
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Chris Jackson @cajackson.org · 23/09/2026
I don't think those are cells, it looks like colorized DIC to me. Most of that stuff is probably intracellular structure.
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Chris Jackson @cajackson.org · 22/09/2026
This exact thing is why I just started setting rasterized=True for everything in matplotlib
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Chris Jackson @cajackson.org · 21/09/2026
time to fight fire with fire my startup has a model that can tell you which embryo is smartest (+28 iq points) yes its a rng no i wont be around in 20 years to give you a refund
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Chris Jackson @cajackson.org · 21/09/2026
There have been several Very NYC Specific conversations happening that are not lined up with how things are done in Not NYC Feels good, like we're back to 2015 twitter
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Chris Jackson @cajackson.org · 21/09/2026
'we should add G&T programs to underperforming schools' is a NYC opinion that starts a fight
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Chris Jackson @cajackson.org · 21/09/2026
You may or may not be right about that but NYC has a 'successful' G&T tracking & specialized school system, and if you want to make changes to it a very large number of very angry people will tell you how much they dont like you
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Chris Jackson @cajackson.org · 21/09/2026
You dont really get tracked within a school you get tracked by going to a different school
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Chris Jackson @cajackson.org · 21/09/2026
NYC also does tracking but it's done at the school level
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Chris Jackson @cajackson.org · 21/09/2026
yes, the plot is awful, but in fairness you also have to consider that the writing is awful too
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Chris Jackson @cajackson.org · 21/09/2026
fair reaction to terry goodkind
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Reposted by Chris Jackson
Bethany Brookshire @beebrookshire.bsky.social · 17/09/2026
People are using AI to impersonate real science journalists. And one even got PUBLISHED. In Science. www.linkedin.com/posts/caroli...
linkedin.com
Fake Caroline update: The person who was impersonating me managed to get an article published in Science, under my by-line. And they got paid for it! I've seen the pitches (bad), and the email…...
Fake Caroline update: The person who was impersonating me managed to get an article published in Science, under my by-line. And they got paid for it! I've seen the pitches (bad), and the email chai...
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Reposted by Chris Jackson
André Marques @amarques.bsky.social · 16/09/2026
Out today in Nature: sex without crossovers. Rhynchospora tenuis makes pollen, fertilises and sets seed, yet 0 crossovers in 10,997 pollen nuclei. Chromosome drive and ~87% seed abortion rebuild the mother's genotype, so the offspring are clones. doi.org/10.1038/s415...
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The Onion @theonion.com · 16/09/2026
Gas Station Price Sign Using Scientific Notation
Gas Station Price Sign Using Scientific Notation
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Chris Jackson @cajackson.org · 16/09/2026
Yeah, I've published and reviewed there in the past but I just flat out don't understand how it works now and don't have the energy to figure it out
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Chris Jackson @cajackson.org · 16/09/2026
Temu Nature Science-ish reports Trends in Things That Have Cells
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Chris Jackson @cajackson.org · 15/09/2026
Suitsupply
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Chris Jackson @cajackson.org · 14/09/2026
oh no you can't get me again with 'the jets are good (n=1 game)' I have been on this ride before
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Reposted by Chris Jackson
Michael Hendricks 🇨🇦 @michaelhendricks.bsky.social · 13/09/2026
Thread. Apologies in advance, I've been grinding away for weeks on a grant with maybe a 10% success rate. Canadian researchers work in buildings held together with duct tape, run labs on shoestrings, and spend more and more time competing for lower and lower success rate operating programs.
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Matt Bors @mattbors.bsky.social · 14/09/2026
It was exactly ten years ago today, on my 33rd birthday, that I posted this comic online.
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The Onion @theonion.com · 12/09/2026
Savannah Bananas Commemorate 9/11 With Solemn ‘Macarena’ Performance
theonion.com
Savannah Bananas Commemorate 9/11 With Solemn ‘Macarena’ Performance
SAVANNAH, GA—In remembrance of the lives lost on that fateful day, sources confirmed that the roster of the Savannah Bananas took to the field prior to Friday’s game to commemorate the 25th anniversar...
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Chris Jackson @cajackson.org · 11/09/2026
Oh sorry it's from contextlib import suppress Thats what I get for posting python with a phone
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Chris Jackson @cajackson.org · 11/09/2026
I think this works as a one liner, but I just write the except pass block from contextmanager import suppress with suppress(KeyError): return d[k]
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Chris Jackson @cajackson.org · 11/09/2026
I would probably do try: return d[k] except KeyError: pass # other stuff to do
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Reposted by Chris Jackson
Nick Stroustrup @nstroustrup.bsky.social · 05/09/2026
Did you know that the cells of old animals contain much less mRNA than the cells of young ones? Let me share with you some results from an ongoing project in the lab, where we are finding that a progressive depletion of total mRNA abundance is a crucial part of aging 1/22
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Data Colada @datacolada.bsky.social · 02/09/2026
Colada[139] Artificial Deadlines Part 2 Evidence of fraud in the 25 year old gradesheet behind the key finding in an influential paper on deadlines and procrastination. datacolada.org/139
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Boston Review @bostonreview.bsky.social · 27/08/2026
Biomedical scientist (and former editor-in-chief of @science.org) @jeremymberg.bsky.social defends undirected science and notes, “It is hard for scientists to support a party whose members seem to think that bringing a snowball to the floor of the Senate refutes the concept of climate change.”
bostonreview.net
In Defense of Undirected Science
Jeremy Berg responds to Zeynep Pamuk in our forum, “How to Save Science.”
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Chris Jackson @cajackson.org · 28/08/2026
Right wing media is going all in on anti-canada, it's a right wing US position moving forward The new york post ran like a week of articles about the Maple Leaf Menace Real 'didnt get the joke in Canadian Bacon' stuff, but it's happening
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Reposted by Chris Jackson
Fietser Brandon @americanfietser.bsky.social · 27/08/2026
The American mind could never comprehend such an enabling and accommodating system of transportation. 📍Finland 🇫🇮
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Chris Jackson @cajackson.org · 26/08/2026
Don't think this guy would sign a letter for me if I got fired for teaching about climate change tbh
Throughout this time, Kalkstein tried to get a letter to Defense Secretary Pete Hegseth through his chain of command, but Sussman, who shared the letter with Stars and Stripes, said it never left campus. The professor argued that exaggerated positions of climate change made under President Joe Biden politicized the field, “making it difficult to separate fact from fiction.”
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Chris Jackson @cajackson.org · 24/08/2026
Is there any way to do that without driving up the price of refined products accordingly in Canada?
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Reposted by Chris Jackson
Zack Labe @zacklabe.com · 23/08/2026
🚨 Preliminary daily data shows we just broke the all-time highest global sea surface temperature in this record... Download high-resolution graphic at zacklabe.com/climate-chan.... This data (extrapolar ocean) is provided by @copernicusecmwf.bsky.social ERA5. 🌊
Graph showing daily global mean sea surface temperatures for 2026. This is also compared to the daily data from the 1981-2010 average and 1991-2020 average. Annotations are also shown to the current year with the other years from 1940 to 2026. There is a seasonal cycle. There is a long-term warming trend. 2023 and 2024 are also indicated, which were the warmest years on record. Data is from ECMWF ERA5 reanalysis and updated through 21 August 2026.
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Tobias Warnecke @tobiaswarnecke.bsky.social · 22/08/2026
Who needs chromatin anyway...? NOT THIS GUY! www.biorxiv.org/content/10.6... 1/n
biorxiv.org
Chromatin is dispensable for bacterial life
Inside cells, DNA is intimately associated with proteins, forming chromatin. The protein constituents of chromatin vary across the tree of life: histones are the principal building blocks of chromatin...
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Jeremy Berg @jeremymberg.bsky.social · 21/08/2026
Let the shit show begin (actually continue)... www.nih.gov/news-events/... No NIH experience at all as far as I can tell. No significant management experience. Vaccine injury trial expert witness.
nih.gov
Pediatric neurologist Dr. John Gaitanis to lead NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development
Dr. Gaitanis is set to begin his role on August 23, 2026.
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Chris Jackson @cajackson.org · 21/08/2026
gold standard meritocracy
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Grace Lindsay @neurograce.bsky.social · 20/08/2026
Teaching "AI use" in college (not related to teaching how AI is built) is silly because 1.) the tools are meant to be user friendly with minimal training and 2.) they change so often your education would be good for about a semester
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Dhruv Mehrotra @dmehro.bsky.social · 19/08/2026
NEW: Flock has said for years its cameras don’t identify or track people. We obtained the code for its police AI and rebuilt parts of it. The tool can find witnesses, surface associates, search people by race or physical description, and flag vehicles by how they move. W/ @dell.bsky.social
wired.com
Flock Has a Powerful New AI Tool for Police. We Got Its Code
Flock’s surveillance cameras have already sparked outrage. WIRED reconstructed its next-generation AI system, already in use by some police, to confirm it goes much further than tracking license plate...
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Chris Jackson @cajackson.org · 19/08/2026
Moderna doesn't sell chemo drugs so they don't give a shit about how profitable they are They do sell mrna therapeutics and if they're profitable, they'll sell them
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