Fascinating. Taking a look at your preprint now. You may be interested in our observations that soma sizes in fly brains seem to “shrink”. This can be slowed by overexpressing Myc, which is a major Pol2 amplifier. www.biorxiv.org/content/10.1...
biorxiv.org
Brain-wide reductions in cell size and volume emerge early during adulthood in Drosophila melanogaster
Aging is accompanied by complex cellular changes in the brain, yet alterations in cell size and brain volume during early adulthood remain poorly characterized. We used flow cytometry to examine cell ...