Author summary Mammalian RAD52 is a protein that protects DNA integrity through its roles in DNA repair and replication, and is being developed as a target for cancer treatment. To identify factors th...

Here the authors identify PCNA, a master regulator of DNA replication, as a ubiquitin substrate for the BRCA1/BARD1 heterodimer. This modification is crucial to avoid the appearance of unreplicated DN...

PhD Project - MRC DiMeN Doctoral Training Partnership: Understanding how damaged DNA is excised and repaired to maintain genome integrity and prevent cancer. at University of Sheffield, listed on Find...