Sign in

brumbaugh-lab.bsky.social

@brumbaugh-lab.bsky.social
89 followers 73 following 14 posts
PostsRepliesMedia
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 26/06/2026
I'm looking forward to the career panel this year at the annual meeting for the International Society for Stem Cell Research! If you are going to be in Montreal and have an interest, come check us out. #ISSCR2026 invt.io/1bxb8rgcvr3 @isscr.org
invt.io
I'm speaking at ISSCR 2026 Annual Meeting, join me
Register now
010
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 12/06/2026
I am working with @stemcellnetwork.ca & @isscr.org to understand the needs of trainees & employers in regenerative medicine. We are seeking input through a brief survey: lnkd.in/eFdbYQrr Help inform future training and workforce development by completing the survey and sharing it with your networks!
lnkd.in
2026 ISSCR-SCN Workforce Survey
Please click the link to complete this form.
020
Reposted by @brumbaugh-lab.bsky.social
Stem Cell Network @stemcellnetwork.ca · 04/06/2026
(1/2) 📣 Help shape the future of workforce development in #StemCells and #RegenerativeMedicine! SCN and @isscr.org invite members of the global stem cell research and regenerative medicine community – from all career stages – 🔗 form.jotform.com/261107195653...
Global Workforce Development Survey
101
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 09/06/2026
Check out our new preprint: (www.biorxiv.org/content/10.6...) that highlights estrogen signaling in trophoblast development. Our data suggest that increased dosage of NRIP1 impairs this pathway, contributing to placental defects linked to Down syndrome. Great work @deirdrelogsdon.bsky.social & team!
051
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 11/02/2026
The @isscr.org and @stemcellnetwork.ca have launched a working group on Global Workforce Development in Stem Cell Research and Regenerative Medicine. I'm excited to co-chair this initiative with Dr. Danielle Spice and to work with an impressive set of trainees and early-career investigators. (1/2)
122
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 03/01/2026
Cool study from the @efapostolou29.bsky.social looking at plasticity in B cells. Check it out!
010
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 15/11/2025
The @isscr.org and @stemcellnetwork.ca have launched an important initiative to understand the needs of both employers and the future workforce. Check out the information below and consider applying to join the working group or nominate someone that you feel could provide good perspective!
021
Reposted by @brumbaugh-lab.bsky.social
Florencia Levin Ferreyra @levin-ferreyra.bsky.social · 04/11/2025
There are many ways to make your voice heard and participate in all that the #ISSCR2026 Annual Meeting has to offer! Discover how to get involved, including submitting an abstract, proposing a science spotlight, hosting a meet-up hub, and more! invt.io/1lxby1coomp @isscr.org
032
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 29/10/2025
Fun project with @distefanolab.bsky.social looking at RNA regulation in cell fate decisions. Check out the great summary below and see the full work in @natbiotech.nature.com: www.nature.com/articles/s41...
nature.com
Selective RNA sequestration in biomolecular condensates directs cell fate transitions - Nature Biotechnology
Stem cell differentiation is controlled by manipulating RNA condensates.
181
Reposted by @brumbaugh-lab.bsky.social
Nature Biotechnology @natbiotech.nature.com · 28/10/2025
Selective RNA sequestration in biomolecular condensates directs cell fate transitions - @distefanolab.bsky.social @brumbaugh-lab.bsky.social go.nature.com/3X215du
go.nature.com
Selective RNA sequestration in biomolecular condensates directs cell fate transitions - Nature Biotechnology
Stem cell differentiation is controlled by manipulating RNA condensates.
24514
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 13/05/2025
Check out this new preprint with @distefanolab.bsky.social lab! The manuscript focuses on RNA processing in the form of sequestration into P-bodies in the context of development.
041
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 27/03/2025
Thanks to @isscr.org for this wonderful recognition! And thanks to my colleagues and ISSCR for thoughtfully and carefully working on important policy and regulatory matters. Read more about the award and my fellow honorees. invt.io/1bxbk540w9k @isscr.org
invt.io
I am a 2025 ISSCR Public Service Award Honoree.
Learn more
021
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 27/03/2025
Thanks to @cp-cellchembiol.bsky.social, @iamzico.bsky.social and Ramesh Shivdasani for this thoughtful discussion of our work!
021
Reposted by @brumbaugh-lab.bsky.social
stadtfeldlab.bsky.social @stadtfeldlab.bsky.social · 13/03/2025
Our work on the regulation is out www.cell.com/stem-cell-re...! Congrats to our collaborators in the Vierbuchen and Mezey labs. It turns out that genetic variation has to be very much considered if you want to harness stem cells safely in biomedicine. #pluripotency #epigenetics #stemcells
cell.com
Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells
Pluripotent stem cells are susceptible to acquiring detrimental epigenetic abnormalities, posing a hurdle to their safe use in biomedical applications. Using pluripotent cells with defined genetic bac...
0148
Reposted by @brumbaugh-lab.bsky.social
Nature Cell Biology @natcellbio.nature.com · 19/02/2025
💫NEW: @brumbaugh-lab.bsky.social, Dempsey & co show that #H3K36 methylation maintains #intestinal epithelial fate commitment, whereas its suppression induces a plastic state and expression of genes involved in #regeneration. 👉🏿https://rdcu.be/eayN3 www.nature.com/articles/s41...
nature.com
H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium - Nature Cell Biology
Pashos et al. show that H3K36 methylation maintains intestinal epithelial fate commitment, whereas its suppression, which is also observed upon injury, induces a plastic state and expression of genes ...
0204
Reposted by @brumbaugh-lab.bsky.social
Stylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 31/01/2025
🥂Congrats to @brumbaugh-lab.bsky.social & co for their new study in @naturecellbiology.bsky.social showing that H3K36 methylation maintains #intestinal epithelial fate commitment and is involved in #regeneration. rdcu.be/d8awu www.nature.com/articles/s41...
rdcu.be
H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium
Nature Cell Biology - Pashos et al. show that H3K36 methylation maintains intestinal epithelial fate commitment, whereas its suppression, which is also observed upon injury, induces a plastic state...
0123
Reposted by @brumbaugh-lab.bsky.social
Bruno Di Stefano @distefanolab.bsky.social · 28/01/2025
1/ Pleased to share our review, published today @natrevimmunol.bsky.social, highlighting how biomolecular condensates enhance the precision and flexibility of gene regulatory networks that guide fate decisions during normal and pathological immune cell development. www.nature.com/articles/s41...
nature.com
Biomolecular condensates in immune cell fate - Nature Reviews Immunology
Recent studies suggest that biomolecular condensates — membrane-less assemblies of proteins and nucleic acids — are involved in regulating gene expression to ensure proper immune cell development. Thi...
24116
brumbaugh-lab.bsky.social @brumbaugh-lab.bsky.social · 10/01/2025
Our new paper defining the role of H3K36 methylation in regulating cell fate and plasticity is available online: rdcu.be/d5AEc Thanks to our entire team for their tireless work and to the editors at @naturecellbiology.bsky.social for the opportunity!
rdcu.be
H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium
Nature Cell Biology - Pashos et al. show that H3K36 methylation maintains intestinal epithelial fate commitment, whereas its suppression, which is also observed upon injury, induces a plastic state...
1249