Patrick Hsu, David Nagib, and Jonathan Rivnay work in a range of chemistry-related fields

Henri B. Kagan and Kenso Soai win the 2026 Nobel Prize in Chemistry for their work on nonlinear effects and asymmetric catalysis

Song Lin and Liangfang Zhang are awarded $800,000 ‘genius grants’

The first chemically fueled small-molecule walker dances around a sugar molecule without falling off

Using bubbles, crystals, prehistoric rocks, and more, scientists look for signals from the invisible part of the universe

Sequential decarboxylation lets chemists attach electron-rich groups to carbon-carbon double bonds

Oxygen-to-nitrogen swap changes a natural product’s mechanism of action

‘This tiny, beautiful element,’ now accessible with mild conditions, can reduce organic molecules

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Acetyl CoA carboxylase inhibitors have been investigated for treating acne and liver disease, but the discarded candidates show why it’s so hard to make a metabolic medicine

First-time disclosures session at ACS Fall 2026 debuted compounds designed to treat cancer, acne, urinary tract infections, and more

Oxygen-to-carbon swap expands synthesis options for 5-membered aromatics

The country music star broke into song before she was inoculated, and urged her fans to “get out there and get your shot.”

Oxygen-to-carbon swap expands synthesis options for 5-membered aromatics

A daily puzzle game inspired by chemistry and NMR spectroscopy. Build a structure whose spectrum matches today's target.

Space is big again. Chemists should jump on the opportunity for exploratory research

Collective effort is key to avoiding reproducibility struggles that have plagued many scientific fields

The classic alkyl halide–making reaction can, at long last, be used to generate alkyl fluorides

Chemists make simple amides using only inexpensive lab chemicals

Chemists make simple amides using only inexpensive lab chemicals

Mechanistic hack enables chemists to couple molecules that have mismatched reduction potentials

Reducing, reusing, and recycling materials will be essential for long-term extraterrestrial living

Reducing, reusing, and recycling materials will be essential for long-term extraterrestrial living

Scientists aim to put freshly brewed protein and better-preserved food on future space menus