This study reports a bivalent factor, ULTRAPETALA1, that can counteract as well as promote PRC2 activity at hundreds of developmental genes in Arabidopsis thaliana. The pro-PRC2 activity of ULTRAPETAL...

Multicellular development is tightly coupled to the polarization of individual cells, which partitions polar proteins along the cell cortex and can control asymmetric cell division, anisotropic growth...

The authors identify conserved gene networks across fern and angiosperm reproductive development, including between the sporophyte ovule and the fern gametophyte egg-chamber. Repurposing of this netwo...

This study introduces iChIP2, a low-input chromatin immunoprecipitation followed by sequencing method that profiles histone post-translational modifications (hPTMs) simultaneously across diverse eukar...

SINEs are short transposable elements that make up large fractions of mammalian genomes. Known to be transcribed by RNA polymerase III, their regulation has remained largely unexplored. Schnabl-Baumga...

The emergence of the eukaryotes coincided with the diversification of histone proteins and their post-translational modifications by enzymes that constitute the core of eukaryotic chromatin. Yet the e...

RNA viruses co-opt host endomembranes to form replication complexes, often triggering cellular stress and immune responses. Here, we show that Arabidopsis thaliana activates selective autophagy to res...

Experiments in the cnidarian Nematostella vectensis show a role of gene body methylation in transposable element suppression and that epigenetic inheritance is constrained by chromatin context and tra...

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This study reveals that enhanced autophagy in root-hair-forming cells helps Arabidopsis store excess sodium, control oxidative stress and tolerate salt stress.

Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...

Brown algae independently evolved complex multicellularity with an atypical chromatin toolkit, including early loss of DNA methylation and PRC2-mediated gene silencing. By profiling histone modificati...