In early results from our new life sciences research lab, Claude agents found an enzyme system whose function is still unknown.

Closing date: Monday 21 September 2026, 23:59

DIAMOND DeepClust provides an ultra-fast clustering method for organizing the protein universe of life at low sequence identity, enabling large-scale dimensionality reduction and improving downstream ...

Flowering plants are the most widespread group of plants, occupying almost every environment on our planet. They play important roles in maintaining the earth’s biodiversity and have a remarkably…

ARGONAUTE (AGO) proteins are a highly conserved family of RNA-binding proteins that play central roles in gene regulation and developmental process...

Brown algae, a key yet understudied lineage of multicellular eukaryotes, have long lacked tools for functional genomics. Martinho et al. introduce a high-efficiency, transgene-free CRISPR platform ena...

Adaptation of multicellular organisms to new environments can leave distinct signatures in their genomic architecture. Although previous efforts have unveiled the dynamics of (epi)genome evolution, our understanding remains incomplete regarding how phenotypic innovation is achieved by relaxing or constraining the identity of a genome over generations while adjusting to dynamic environments. Using plants, we first compile a list of candidate epigenetic regulators which we refer to as 'epigenetic toolkit' proteins. We propose a new framework for examining the epigenetic toolkit as an evolvable trait during plant adaptation. This could predict how feedback mechanisms between (a)biotic environmental factors and innate regulation of genome architecture can destabilize the homeostatic state of a plant and thereby inherently reshape the (epi)genetic landscapes for both short- and long-term habitat adaptation.

The detectCores() function of the parallel package is probably one of the most used functions when it comes to setting the number of parallel workers to use in R. In this blog post, I’ll try to explai...

Accelerated BLAST compatible local sequence aligner. - bbuchfink/diamond

Individual- and population-level diversity is required for pathogen defense by nucleotide-binding site leucine-rich repeat (NLR) proteins. Teasdale et al. leverage annotated, divergent A. thaliana gen...

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