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Joseph Hughes

@bljog.bsky.social
108 followers 124 following 1.3K posts

bioinformatics.cvr.ac.uk/people/jos… Bioinformatics, phylogenetics, open science, bikes and cycling, ranting. Views my own.

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Joseph Hughes @bljog.bsky.social · 22/09/2026
Deadline for the PhD on "Virome dynamics in wastewater across urban, rural and high-risk settings" is approaching fast: www.gla.ac.uk/research/az/....
gla.ac.uk
University of Glasgow - Research - Research units A-Z - MRC-University of Glasgow Centre for Virus Research - Training & Development - DETECTIVE PhD opportunities
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MRC-UofG Centre for Virus Research @cvrinfo.bsky.social · 15/09/2026
Interested in using genomics, big data and AI to tackle future pandemic threats? The @cvrinfo.bsky.social is recruiting two PhD students through the DETECTIVE Doctoral Network 🦠🕵️‍♂️ shorturl.at/iLrfP
The hexagonal logo of the DETECTIVE project next to a researcher working in a lab
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Sergey Ovchinnikov @sokrypton.org · 14/09/2026
Finally a more intuitaive way to learn pLDDT/pAE? 😎 sokrypton.github.io/protein_figh... (Character idea from @hannes-stark.bsky.social & Alex Waldherr)
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Rod Page @rdmpage.bsky.social · 27/05/2026
Converting images to trees has a long history. @arambaut.bsky.social wrote TreeThief many years ago, @bljog.bsky.social released TreeRipper over a decade ago doi.org/10.1186/1471..., the list goes on. All because people don't share machine readable phylogenies 😞
doi.org
TreeRipper web application: towards a fully automated optical tree recognition software - BMC Bioinformatics
Background Relationships between species, genes and genomes have been printed as trees for over a century. Whilst this may have been the best format for exchanging and sharing phylogenetic hypotheses during the 20th century, the worldwide web now provides faster and automated ways of transferring and sharing phylogenetic knowledge. However, novel software is needed to defrost these published phylogenies for the 21st century. Results TreeRipper is a simple website for the fully-automated recognition of multifurcating phylogenetic trees ( http://linnaeus.zoology.gla.ac.uk/~jhughes/treeripper/ ). The program accepts a range of input image formats (PNG, JPG/JPEG or GIF). The underlying command line c++ program follows a number of cleaning steps to detect lines, remove node labels, patch-up broken lines and corners and detect line edges. The edge contour is then determined to detect the branch length, tip label positions and the topology of the tree. Optical Character Recognition (OCR) is used to convert the tip labels into text with the freely available tesseract-ocr software. 32% of images meeting the prerequisites for TreeRipper were successfully recognised, the largest tree had 115 leaves. Conclusions Despite the diversity of ways phylogenies have been illustrated making the design of a fully automated tree recognition software difficult, TreeRipper is a step towards automating the digitization of past phylogenies. We also provide a dataset of 100 tree images and associated tree files for training and/or benchmarking future software. TreeRipper is an open source project licensed under the GNU General Public Licence v3.
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Kirstyn Brunker @kirstynbrunker.bsky.social · 26/05/2026
🧬 New resource alert! Pleased to share the release of RABV-gDB: a new platform for rabies virus genomic data, analysis, and sequence management developed @cvrbioinfo.bsky.social as part of the RAGE toolkit. 🌐 gdb-web-dev.cvr.gla.ac.uk 🔧 github.com/RAGE-toolkit #Rabies #Genomics #OneHealth
gdb-web-dev.cvr.gla.ac.uk
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MRC-UofG Centre for Virus Research @cvrinfo.bsky.social · 18/05/2026
Great to see a strong CVR contingent at #Vibiom2026 with Hayley Stone and James Herzig from @vibelab.co.uk and Robert Strange, Joseph Hughes and Ulad Litvin from @cvrbioinfo.bsky.social giving talks across the meeting sessions and @davidlrobertson.bsky.social chairing the Phylogenomics session!
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CVR Bioinformatics @cvrbioinfo.bsky.social · 19/05/2026
. @ulad-litvin.bsky.social is presenting his work at #ViBioM2026 @cvrinfo.bsky.social
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Joseph Hughes @bljog.bsky.social · 19/05/2026
Fifth and final @cvrinfo.bsky.social talk at ViBioM 2026. @ulad-litvin.bsky.social presenting viro3d.cvr.gla.ac.uk and other applications of alphafold in virology.
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Joseph Hughes @bljog.bsky.social · 20/04/2026
Fully funded PhD in virology - CVR & The Pirbright Institute Vector-imposed constraints on the evolution and diversity of bluetongue virus. J. Hughes, P. Johnson, M. Guimera Busquets, C. Sanders, N. Forrester-Soto Deadline for application: 08/05/2026 - tinyurl.com/BTVevolution
tinyurl.com
FULLY FUNDED PhD - Vector-imposed constraints on the evolution and diversity of bluetongue virus at University of Glasgow on FindAPhD.com
PhD Project - FULLY FUNDED PhD - Vector-imposed constraints on the evolution and diversity of bluetongue virus at University of Glasgow, listed on FindAPhD.com
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Joseph Hughes @bljog.bsky.social · 16/04/2026
Great delivery by Sarah Little from @grovearmada.bsky.social team @microbiologysociety.org : Scalable Screening of AI Designed Binders that Prevent Virus Entry
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Joseph Hughes @bljog.bsky.social · 14/04/2026
Fleming Prize Lecture @microbiologysociety.org : Unravelling Respiratory Viral Infections: from Bedside to Bench and Back Professor @drtoniho.bsky.social (MRC-University of Glasgow Centre for Virus Research)
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Joseph Hughes @bljog.bsky.social · 14/04/2026
Great presentation from @ulad-litvin.bsky.social @microbiologysociety.org annual conference: How far can AlphaFold go? Lessons from modelling virus–host protein interactions using AlphaFold3.
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Joe Grove @grovearmada.bsky.social · 18/02/2026
​A huge thank you to the team at the MRC-University of Glasgow Centre for Virus Research (CVR) @cvrinfo.bsky.social: @ulad-litvin.bsky.social, @bljog.bsky.social, @spyroslytras.bsky.social, Alexander Jack, and @davidlrobertson.bsky.social.
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Luke Hillary @lukehillary.bsky.social · 27/11/2025
📢 New preprint is out on bioRxiv 📢: How much does virome prep influence our view of the human gut virome? Short answer: a lot. Long answer: doi.org/10.1101/2025... Different methods lead to distinct community structures, richness, and major virus-host abundance patterns. 🧵 1/5
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Ed Hutchinson @socialinfluenza.bsky.social · 27/11/2025
Are you fascinated by viruses? Would you like to design your own original research project in the UK's largest virology centre? Why not come and do a PhD @cvrinfo.bsky.social - application deadline 6th Jan 2026 (1/1): www.findaphd.com/phds/program...
findaphd.com
FindAPhD : The MRC-University of Glasgow Centre for Virus Research (CVR) PhD Funded Programme at University of Glasgow
Apply for a PhD: The MRC-University of Glasgow Centre for Virus Research (CVR) PhD Funded Programme at University of Glasgow
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Dr Liam Brierley @liambrierley.bsky.social · 28/11/2025
What makes bird flu spill over to humans? 4y funded PhD in the genomics and molecular virology behind zoonosis of avian influenza A virus, working with @tompeacock.bsky.social and others between Liverpool, Pirbright, and Uppsala! open to applications until next week!
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Sam J Wilson @samjwilsonphd.bsky.social · 27/11/2025
I think more studies need to be done in humans as it seems likely that antipyretics do more harm than good in some situations. Lowering body temperature could be neutralising a powerful antiviral defence. Thanks for reading this thread.
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Sam J Wilson @samjwilsonphd.bsky.social · 27/11/2025
How does fever work? Our new Science paper shows how elevated body temperature can protect against severe influenza and that avian-origin viruses escape this defence. This is likely one reason why bird flus and some pandemic influenzas can be so severe.🧵 www.science.org/doi/10.1126/...
science.org
Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals
Host body temperature can define a virus’s replicative profile—influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted t...
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IDDjobs @iddjobs.org · 21/11/2025
PhD position (Glasgow, UK) Build lightweight AI tools supporting One Health decision-making. with @kirstynbrunker.bsky.social @bljog.bsky.social @jakelever.bsky.social at @sbohvm.gla.ac.uk More details: iddjobs.org/jobs/2420
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Spyros Lytras @spyroslytras.bsky.social · 28/09/2025
New exciting resource published!! The Viro3D paper is out, describing our comprehensive database of predicted virus protein structures! 💻🧬 Work with @ulad-litvin.bsky.social , @grovearmada.bsky.social , Alex Jack, @bljog.bsky.social , @davidlrobertson.bsky.social www.embopress.org/doi/full/10....
embopress.org
Viro3D: a comprehensive database of virus protein structure predictions | Molecular Systems Biology
imageimageViro3D provides proteome-level, high confidence AI-protein structure predictions for >4,400 viruses, allowing mapping of form and function across the human and animal virosphere. Viro3D i...
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Joe Grove @grovearmada.bsky.social · 26/09/2025
Team effort from @uofgmvls.bsky.social @cvrinfo.bsky.social Science: @ulad-litvin.bsky.social @spyroslytras.bsky.social @davidlrobertson.bsky.social and @bljog.bsky.social Website: Alexander Jack Funding: @medresfdn.bsky.social @ukri.org @wellcometrust.bsky.social @royalsociety.org
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Joseph Hughes @bljog.bsky.social · 15/05/2025
Kieran Lamb from @davidlrobertson.bsky.social gets best poster prize at EVBC meeting in Lisboa
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MRC-UofG Centre for Virus Research @cvrinfo.bsky.social · 08/05/2025
📄 NEW | Genetic Study shows that Wildlife Trade sparked COVID-19 Virus Emergence in Humans SARS-CoV-2 arrived in Wuhan too quickly for bat hosts to have carried it there. cell.com/cell/fulltex... gla.ac.uk/research/az/... @davidlrobertson.bsky.social @spyroslytras.bsky.social @bljog.bsky.social
cell.com
The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2
Recombination-aware evolutionary analyses of the entire genomes of SARS-CoV-1-like and SARS-CoV-2-like viruses indicate that SARS-CoV-1 and SARS-CoV-2 descend from bat coronaviruses that circulated as...
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Richard Branson @richardbranson.bsky.social · 25/02/2025
For the US to side with Russia and North Korea to oppose a UN resolution condemning the illegal invasion of Ukraine defies all common sense and adds insult to the countless injuries suffered by the brave Ukrainian people. edition.cnn.com/2025/02/24/p...
edition.cnn.com
US joins Russia to vote against UN resolution condemning Russia’s war against Ukraine | CNN Politics
The United States joined Russia to vote against a UN General Assembly resolution condemning Russia’s war against Ukraine Monday in a stunning shift from years of US policy.
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Research Professional News @resprofnews.bsky.social · 13/02/2025
‘I do not want a fellowship that can include such actions.’ Elon Musk's fellowship is undermining the purpose of the Royal Society, writes resigning fellow @andrewmillar.bsky.social. In this piece, he tells us why he feels enough is enough. www.researchprofessionalnews.com/rr-news-uk-v...
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Spyros Lytras @spyroslytras.bsky.social · 04/02/2025
Recently we have been doing lots of work on how modern #AI methods can be applied to studying virus evolution, so it felt like great timing to write a perspective about it! Very happy to see our paper as editor's pick in JVI!🥳🥳 doi.org/10.1128/jvi....
doi.org
Pathogen genomic surveillance and the AI revolution | Journal of Virology
Genomic pathogen sequencing during the COVID-19 pandemic highlighted the critical role of surveillance in understanding the persistence of SARS-CoV-2 in the human population despite high levels of pro...
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Theo Sanderson @theo.io · 22/01/2025
🎺 PhD studentship available at @lshtm.bsky.social and RVC! @influenzal.bsky.social and I are advertising for a project to investigate the unexpected phenomenon that mutagenic antiviral drugs can give rise to viruses with hundreds of mutations which are still viable. 🧵 www.lshtm.ac.uk/study/fees-a...
lshtm.ac.uk
2025-26 Bloomsbury Colleges PhD Studentships | LSHTM
The Bloomsbury Colleges group was set up in 2004 and consists of five institutions: Birkbeck, London School of Hygiene & Tropical Medicine (LSHTM), the Royal Veterinary College (RVC), the School of Or...
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Spyros Lytras @spyroslytras.bsky.social · 22/01/2025
This paper has been a side project for quite a few years now, so I'm extra happy to see it published!! big thanks to co-lead Sej Modha as well as @bljog.bsky.social and Richard Orton + all the experts who gave valuable feedback at conferences and over the internet! 😁😁
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Joseph Hughes @bljog.bsky.social · 17/01/2025
As a WOAH Collaborating Centre, we’re excited to announce our 8th annual Viral #Bioinformatics & #Genomics training course from 16th - 20th June 2025! 🧬 @cvrinfo.bsky.social 📅 Register by 30 April: 👉 bit.ly/VBGCourse2025 📲 Or scan the QR code to join.
A view of the Garscube campus from aboveA QR code for accessing further information and registration
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Dr. Rowan Durrant @rowandurrant.bsky.social · 28/12/2024
Another human rabies death in the US:
local12.com
Person dies from rabies in Northern Kentucky, first rabies death in state since 1996
The victim, a resident of Northern Kentucky, succumbed to the disease after receiving medical treatment in both Kentucky and Ohio.
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Eddie Holmes @eddieholmes.bsky.social · 29/12/2024
Another virus outbreak (Severe Fever with Thrombocytopenia Syndrome Virus -SFTSV) associated with fur farming. It needs to stop. www.tandfonline.com/doi/full/10....
tandfonline.com
Concurrent Severe Fever with Thrombocytopenia Syndrome Virus Outbreaks on Multiple Fox Farms, China, 2023
The role of farmed animals in the viral spillover from wild animals to humans is of growing importance. Between July and September of 2023 infectious disease outbreaks were reported on six Arctic f...
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Jeff Nachtigall @dirklancer.bsky.social · 28/12/2024
Not sure of the original source of this, but the depiction with the final domino set to crush the pusher is devastatingly accurate.
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Brent Toderian @brenttoderian.bsky.social · 28/12/2024
“Many Swedish cities, including Stockholm, prioritize snow clearance very differently. They now clear walkways & bike paths first, especially those near bus stops & primary schools. Next, they clear local roads, & then, finally, highways.” Via @usa.streetsblog.org usa.streetsblog.org/2018/01/24/w...
usa.streetsblog.org
Why Sweden Clears Snow-Covered Walkways Before Roads — Streetsblog USA
It's part of "gender-balanced" policy that reflects the fact that women walk more than men.
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Spyros Lytras @spyroslytras.bsky.social · 21/12/2024
An exciting resource we put together with Ulad Litvin, @grovearmada.bsky.social Alexander Jack, @davidlrobertson.bsky.social and @bljog.bsky.social bsky.app/profile/grov...
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Joe Grove @grovearmada.bsky.social · 20/12/2024
✨ This was a huge team effort by Ulad Litvin, @spyroslytras.bsky.social, Alexander Jack, David Robertson and @bljog.bsky.social Thank you to our funders MRC @ukri.org , @medresfdn.bsky.social, @wellcometrust.bsky.social. We can't wait to see what discoveries you'll make with Viro3D in 2025! 🚀
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🧬Jacob L Steenwyk @jlsteenwyk.bsky.social · 25/11/2024
NEW Publication!😄 Here, we show how #PhyKIT — a broadly applicable toolkit for #phylogenomics — can be used to construct phylogenomic data matrices (& quantify biases therein), detect anomalies in predicted orthology, calculate gene-gene coevolution, & more! 🔗: tinyurl.com/yc5ja4xz
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Joseph Hughes @bljog.bsky.social · 25/11/2024
So happy to see that there are still people with a moral compass
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Dorothy Bishop @deevybee.bsky.social · 25/11/2024
New blogpost: deevybee.blogspot.com/2024/11/why-...
deevybee.blogspot.com
Why I have resigned from the Royal Society
The Royal Society is a venerable institution founded in 1660, whose original members included such eminent men as Christopher Wren, Robert H...
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Joseph Hughes @bljog.bsky.social · 25/11/2024
www.santafe.edu/culture/podcasts/ep… Great and fun podcast on intelligence!
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Antonia Ho @drtoniho.bsky.social · 25/11/2024
Interested in pursuing virus research? The 2025 intake for the @cvrinfo.bsky.social #PhD programme now open to applications! 🏴󠁧󠁢󠁳󠁣󠁴󠁿🦠🧫🔬🧬🧑🏻‍🔬 #AcademicSky #IDSky
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Joseph Hughes @bljog.bsky.social · 06/11/2024
Our @NorthWestBio1 PhD project applying natural language processing to virology literature is now open for applications: Get in touch with if you are interested and want to find out more. gla.ac.uk/postgraduate/d…
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Joseph Hughes @bljog.bsky.social · 30/10/2024
Preparing for Pandemics: How to Communicate? events.bookitbee.com/university-of-…
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Joseph Hughes @bljog.bsky.social · 14/09/2024
Wouldn't it be nice to have a beautiful street art on Sinclair drive to inspire the kids walking to @BattlefieldPS and the toddlers in @SinclairNursery
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Joseph Hughes @bljog.bsky.social · 17/04/2024
Bioinformatic system administrator position open @UofGlasgow to work with @CVRbioinfo Come join us! tinyurl.com/cvrbioinfsysad…
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Joseph Hughes @bljog.bsky.social · 20/03/2024
Comment: Junior Research Software Engineer/ Research Software Engineer - web resources fo dlvr.it/T4Ljck
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Joseph Hughes @bljog.bsky.social · 14/03/2024
Applications are now closed for the 7th Annual training course on Viral Bioinformatics and Genomics (24 – 28 June 2024) run by the @CVRbioinfo team but if you want to be kept in the loop about future courses, you can add your details here: . . tinyurl.com/future-training
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Joseph Hughes @bljog.bsky.social · 16/01/2024
Applications are now open for the annual viral bioinformatics training course @CVRinfo run by the @CVRbioinfo team. You can find further details at and apply soon here to avoid disappointment: bit.ly/vgb2024-details bit.ly/vgb2024
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Joseph Hughes @bljog.bsky.social · 07/12/2023
Congratulations to Dr @SpyrosLytras and Bowen for graduating from @CVRbioinfo. I look forward to hearing about all the great things you will do. @UofGlasgow @CVRinfo
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Joseph Hughes @bljog.bsky.social · 18/10/2023
The Evolution, Pathogens and Public Health meeting @uofgarc is kicking off to a good start #epph2023. Thanks to @GenSocUK and @CVRbioinfo for support.
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Joseph Hughes @bljog.bsky.social · 03/10/2023
One day meeting at the University of Glasgow @CVRinfo @CVRbioinfo on the 18th of October on Evolution, Pathogens and Public Health. Register here before the 10th of October: For a list of confirmed speakers and posters: forms.office.com/e/SrJ79bXBf6 bit.ly/epph2023
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