Reposted by Abin BiswasGabriel Neurohr @gabrielneurohr.bsky.social · 15/07/2026We just preprinted Marianna’s PhD work in which we asked: How does non-coding DNA affect cell physiology? And why do some organisms have so little of it while other genomes are 99% non-coding? 1146
Reposted by Abin BiswasSimone Reber @simonereber.bsky.social · 20/03/2026Wrote this for @gucklab.bsky.social 💔 onlinelibrary.wiley.com/share/YG8NRH...onlinelibrary.wiley.comBiophysik: Eine 3D‐Dichtekarte der ZelleReader environment loaded 072
Reposted by Abin BiswasSimone Reber @simonereber.bsky.social · 06/03/2026In vitro reconstitution is powerful: we can rebuild Plasmodium microtubule architectures from purified components and recapitulate what cells actually do 🤩 Thanks to an incredible team that made this possible 🙌 @carolynmoores1.bsky.social in particular rdcu.be/e7eM2rdcu.beAdaptations in Plasmodium tubulin determine distinct microtubule architectures, mechanics and drug susceptibilityNature Communications - Tubulin conservation presents a challenge to understanding microtubules’ diverse functions in eukaryotes. Here, the authors characterize the structures of P.... 0279
Reposted by Abin BiswasSimone Reber @simonereber.bsky.social · 23/02/2026Density. Crowding. Tomato. Tomato 🍅 @gabepopkin.bsky.social kin.bsky.social @quantamagazine.bsky.social Thx for covering the debate! We promise we're all friends 🥰 @liamholt.bsky.social & @gwgl.bsky.social Nothing would have been possible without @gucklab.bsky.social @vasilyzaburdaev.bsky.socialquantamagazine.orgThe Biophysical World Inside a Jam-Packed Cell | Quanta MagazineInnovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals. 1217
Reposted by Abin BiswasQuanta Magazine @quantamagazine.org · 18/02/2026Recent studies in living animals reveal that the cytoplasm is a thick, jam-like fluid. And yet, miraculously, hoards of molecules find their way to each other in every crowded cell. www.quantamagazine.org/the-biophysi... 03710
Reposted by Abin BiswasBrugues Lab @brugueslab.bsky.social · 07/01/2026Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de 814960
Reposted by Abin BiswasMax Planck Institute for the Science of Light (MPL) @mpi-scienceoflight.bsky.social · 25/09/2025Researchers from #MPZPM and @mpiib-berlin.mpg.de have now compared the ratio of nuclear and cytoplasmic density in different organisms and come to a surprising conclusion: the cell nucleus in eukaryotes is less dense than the rest of the cell. 👉 mpzpm.mpg.de/news/news-de... #Physics #Medicine 0174
Reposted by Abin BiswasMax Planck Institute for Infection Biology @mpiib-berlin.mpg.de · 19/09/2025📃 New paper alert! The Zychlinsky Lab and @raunser-lab.bsky.social identified the first protein that converts chromatin into an immune effector: Myeloperoxidase transforms chromatin into neutrophil extracellular traps. Now published in @nature.com: www.nature.com/articles/s41...nature.comMyeloperoxidase transforms chromatin into neutrophil extracellular traps - NatureMyeloperoxidase, a highly expressed neutrophil protein, disassembles nucleosomes, facilitating neutrophil extracellular trap (NET) formation, and binds stably to NETs extracellularly. 1138
Reposted by Abin BiswasMax Planck Institute for Infection Biology @mpiib-berlin.mpg.de · 08/09/2025📢 Voices in Infection Biology ☀️ We're back from summer break with a talk by Jan Skotheim from @stanford.edu, kindly hosted by @simonereber.bsky.social. 🗓️ Wednesday, September 10 🕓 4 pm 📍 on-site seminar (Berlin) Event info: www.mpiib-berlin.mpg.de/events/42144... 142
Reposted by Abin BiswasBrugues Lab @brugueslab.bsky.social · 03/09/2025Patrick's paper is finally out, a label-free method to measure the composition of multicomponent biomolecular condensates!nature.comA label-free method for measuring the composition of multicomponent biomolecular condensates - Nature ChemistryBiomolecular condensates are made of multiple components but current techniques cannot capture their complex composition quantitatively. Now it has been shown that the dense-phase binodal point defini... 46722
Reposted by Abin BiswasMax Planck Institute for Infection Biology @mpiib-berlin.mpg.de · 15/08/2025🚨 Paper alert! Check out the latest work from the Reber Lab 📌 New research by @simonereber.bsky.social and @biswashere.bsky.social, now published in @natcomms.nature.com 🥳 032
Abin Biswas @biswashere.bsky.social · 15/08/2025It's here! It's out! AND It's become better 🐸 Our fundamental work on intracellular density distributions, how it influences cellular organisation & how deviations occur during pathophysiological states like senescence is out in @natcomms.nature.com Congratulations & thank you to the entire team! 040
Reposted by Abin BiswasNature Cell Biology @natcellbio.nature.com · 02/08/2025🍹Kletter et al. show that cell state-specific cytoplasmic density controls spindle architecture and scaling in neural differentiation, suggesting that the physical properties of the cytoplasm are a determinant in #organelle size control. bit.ly/4mhMvsUbit.lyCell state-specific cytoplasmic density controls spindle architecture and scaling - Nature Cell BiologyKletter et al. show that cell state-specific cytoplasmic density controls spindle architecture and scaling in neural differentiation, suggesting that the physical properties of the cytoplasm are a det... 22911
Reposted by Abin BiswasMax Planck Institute for Infection Biology @mpiib-berlin.mpg.de · 13/06/2025🚨 New paper alert: cytoplasm density controls spindle architecture and size. This shows for the first time that a physical property of the cytoplasm regulates the spindle. Congrats to @simonereber.bsky.social, @tobiaskletter.bsky.social and everyone who contributed. 👉 www.nature.com/articles/s41...nature.comCell state-specific cytoplasmic density controls spindle architecture and scaling - Nature Cell BiologyKletter et al. show that cell state-specific cytoplasmic density controls spindle architecture and scaling in neural differentiation, suggesting that the physical properties of the cytoplasm are a det... 051
Abin Biswas @biswashere.bsky.social · 13/06/2025Congratulations to everyone involved!!!🎉🍾🤩 Fortunate to have contributed to this beautiful work demonstrating how cytoplasmic density tunes mitotic spindle architecture 🔬📈🐸 030
Reposted by Abin BiswasSimone Reber @simonereber.bsky.social · 19/05/2025✨We are looking for a PhD student interested in physical cell bio, imaging 🔬, biochemistry, #Xenopus 🐸 & #microtubules ✨ Join us @mpiib-berlin.mpg.de! 12729
Abin Biswas @biswashere.bsky.social · 10/05/2025Beautiful work by @mctwo.bsky.social investigating the spatio-temporal dynamics of the cytoplasm using label-free tools and 🐸 extracts! 🐸 + 🔬 + 📈 = ✨ w. @gucklab.bsky.social , @simonereber.bsky.social , @vasilyzaburdaev.bsky.social www.biorxiv.org/content/10.1...biorxiv.org 0104
Reposted by Abin BiswasFEBS Letters @febsletters.bsky.social · 11/04/2025Congrats to Mirko Pleitner for winning the FEBS Letters Poster Award! Mirko from the lab of @simonereber.bsky.social at @humboldtuni.bsky.social presented an excellent poster at the @embo.org @embl.org Symposium "Wild frontiers of model organisms". Thanks for the fantastic insights! #EESWildModels 0123
Reposted by Abin BiswasSimone Reber @simonereber.bsky.social · 13/04/2025Congrats Mirko! Proud lab colleagues & 🐸 053
Reposted by Abin BiswasWehner lab | Neuroregeneration @wehnerlab.bsky.social · 27/01/2025Excited to share the latest work from our lab: www.biorxiv.org/content/10.1...biorxiv.orgBiphasic inflammation control by dedifferentiated fibroblasts enables axon regeneration after spinal cord injury in zebrafishFibrosis and persistent inflammation are interconnected processes that inhibit axon regeneration in the mammalian central nervous system (CNS). In zebrafish, by contrast, fibroblast-derived extracellu... 22810
Reposted by Abin BiswasMax Planck Institute for Infection Biology @mpiib-berlin.mpg.de · 10/01/2025📰 For a quick summary, read our website article: www.mpiib-berlin.mpg.de/2176621/news...mpiib-berlin.mpg.deSome frogs like it hot, others like it coldResearchers from the Max Planck Institute for Infection Biology show, how clawed frog species inhabit different climate zones thanks to small molecular adaptations 043
Reposted by Abin BiswasGabriel Neurohr @gabrielneurohr.bsky.social · 06/12/2024Did you ever wonder how cytoplasmic properties influence mitotic spindle architecture? Come join us for an exciting seminar next Wednesday by @simonereber.bsky.social 0116
Reposted by Abin BiswasSimone Reber @simonereber.bsky.social · 27/11/2024Two positions in our lab 🐸🐛🔬 #malaria #xenopus #microtubules #biophysics #imaging #PhDlife 087