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Department of Biomedicine🔬🧪

@biomedizin.unibas.ch
247 followers 73 following 94 posts

As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance our understanding of health and disease.

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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 29/09/2026
A new approach to anatomy teaching at the DBM: Felix Margenfeld and colleagues developed an ultrasound-guided dissection course, connecting real-time ultrasound with anatomical structures to strengthen students’ 3D understanding of the human body. 🔗 edoc.unibas.ch/entities/pub... @unibas.ch
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 24/09/2026
The fourteenth issue of our DBM Newsletter is here! Happy reading!👇🏼👇🏼👇🏼 DBM Newsletter Issue 14: issuu.com/departementb... @biomedizin.unibas.ch #Newsletter #Research #Science #Biomedicine
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 22/09/2026
Congratulations to Gregor Hutter on his appointment as Clinical Professor of Neurosurgery at @unibas.ch. At @biomedizin.unibas.ch, @hutterlab.bsky.social studies how immune cells can be harnessed against glioblastoma and develops new therapies. Congratulations, Gregor! 🎉
Professor Gregor Hutter.
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 15/09/2026
🎉Congratulations to David Bargiela on his @snsf.ch Ambizione Grant! His new project investigates how glioblastoma cells survive treatment and adapt their metabolism following immune attack – with the aim of identifying vulnerabilities that could improve responses to immunotherapies! What a success!
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 09/09/2026
The 2026 DBM Summer Symposium took place on September 9. 🧬 We started with a keynote by Prof. @stephenquake.bsky.social, followed by four sessions showcasing research by our scientists. The day concluded with the DBM Paper Prize & Best Presentation Award. 🏆 #DBMSymposium2026 #TeamDBM #Science
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 08/09/2026
A new way to turn the tumor microenvironment against cancer: Researchers from Cambridge and Basel developed small molecules that make macrophages engulf cancer cells while reducing PD-L1-mediated immune suppression. Published in Cancer Research. 👇Publication link below. #CancerResearch
Green-stained macrophages engulf red-labeled cancer cells after treatment with PSEs. The red signal inside the macrophages shows that they have taken up cancer cells. (Image: Valerio Sabatino, University of Basel)
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 27/08/2026
🏆 Congratulations to Prof. Judith Zaugg and Prof. Heinz Läubli, DBM research group leaders and recipients of the 2026 Dora Seif Prize for Cancer Research! A wonderful recognition of their outstanding contributions to cancer research. 👏 #CancerResearch #DoraSeifPrize #DBM @unibas.ch
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 04/08/2026
New in @jamaneurology.com: Jens Kuhle from @biomedizin.unibas.ch, @unibas.ch and @dkf.unibas.ch together with other colleagues shows that the blood biomarker GFAP is associated with progression independent of relapses in multiple sclerosis and may complement NfL. Congratulations to the team! 👏👇
Data from thousands of blood samples allowed the researchers to compare different biological processes involved in multiple sclerosis. (Photo: Kathleen Herrgott, RC2NB)
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 28/07/2026
Dr. @mariuslange.bsky.social has been appointed Tenure-Track Assistant Professor of Systems Developmental Medicine. He combines computational biology & single-cell genomics to study how human tissues & organs develop, thereby advancing our understanding of early childhood development. 👇
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 14/07/2026
🧠 Great news from the Molecular Neuroscience Lab! Professor Andreas Papassotiropoulos has been elected to the German National Academy of Sciences Leopoldina — one of the most prestigious scientific honors in the German-speaking world. Congratulations, Andreas! 🎉 biomedizin.unibas.ch/en/newsdetai...
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 30/06/2026
Another ERC success for @biomedizin.unibas.ch: Judith Zaugg has been awarded an #ERCPoC Grant for HemaTrax, a project improving the prediction of blood toxicity in cancer therapy and drug development. It could support safer treatments and speed up the development of new therapies. 👍 @erc.europa.eu
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 29/05/2026
🔬 Two new studies from the Pinschewer Lab at the DBM shed new light on antiviral immunity — from Lassa fever vaccination to B cell “attrition” in chronic infection. Congratulations to the team! 👏 Nature Communications: www.nature.com/articles/s41... PNAS: www.pnas.org/doi/10.1073/...
Fluorescence microscopy of mouse spleen tissue comparing chronic infection with a virus to which adoptively transferred B cells bind with high affinity (top) versus infection with a virus bound at low affinity (bottom). Green marks the transferred B cells, red the germinal centers where B cells mature, white the surrounding B cell zone. (Dimitrova et al., PNAS 2026, Fig. 2H–I. Reproduced under CC BY licence.)
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 17/04/2026
MISEV2023 sets key guidelines for EV research. With contributions from Edveena Hanser, Diego Kyburz, & an international consortium, the paper is now one of the top ten most-cited papers in JEV (Wiley, 2024). Congratulations to everyone involved. isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 10/04/2026
📺 TV tip The ZDF documentary “plan b: A fresh start for the knee” features research from the @biomedizin.unibas.ch , @unibas.ch, on cartilage regeneration using patients’ own cells. 📅 10 April, 19:40 (ARTE) and 12 April, 15:30 (ZDF) Also available online. Link in comments. @dkf.unibas.ch
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 01/04/2026
Welcome on board @Frauke von Versen. We are happy to have you with us, and we wish you a great start! #Welcome2026 #welcometotheteam #welcomeonboard #TeamDBM @biomedizin.unibas.ch n.unibas.ch DBM News: 👉 biomedizin.unibas.ch/en/newsdetai...
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 31/03/2026
Aβ and tau disrupt memory circuits in Alzheimer’s disease. New work from the @marcaurelbusche.bsky.social Lab at @biomedizin.unibas.ch .ch and @uclhresearch.bsky.social bsky.social links this to synaptic NMDA receptor hypofunction and shows recovery when both pathologies are reduced. 🔗See comments.
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 10/03/2026
🔬 Science moves forward through collaboration! Researchers from @biomedizin.unibas.ch and the Department of Pharmaceutical Sciences (DPhW) came together for the DBM–DPhW Joint Meeting 2026 — a day of inspiring talks, exchange, and new connections across disciplines. 👏 #DBM #DPhW #LifeSciences
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 03/03/2026
Today, we’ve officially launched the Xenium platform at @biomedizin.unibas.ch in collaboration with @bsse.ethz.ch. 🚀 A major step forward for spatial transcriptomics in Basel! 👉 biomedizin.unibas.ch/en/communica...
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 13/02/2026
On Wednesday, we hosted the symposium, “Sex & Gender Differences in Medicine & Research,” with Athena’s Journey. Sex & gender influence disease risk, symptoms & outcomes - yet they are underrepresented in research. Integrating them isn’t optional. It’s essential. #SexandGender #ClosingTheGap #IDWGS
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 23/01/2026
DBM Research Day 2026 has wrapped up! 🎉 There were great talks and lively discussions, as well as an excellent poster session showcasing emerging research across DBM. Thanks to everyone involved! See you in 2027! #DBMResearchDay #Science #TeamDBM @biomedizin.unibas.ch
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 20/01/2026
How does aggressive AML originate? A new study shows that thrombopoietin can prime EVI1+ stem cells, making them more vulnerable to KMT2A fusion–driven leukemia, published in @natcomms.nature.com from the Schwaller lab @biomedizin.unibas.ch. 👉 www.nature.com/articles/s41... #AML @unibas.ch
Wright-Giemsa stained cytospin preparations of murine long-term hematopoietic stem cells. (Image: Hugues-Étienne Châtel-Soulet, University of Basel).
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 14/01/2026
How can a common virus contribute to a rare disease? A new @cp-immunity.bsky.social study from @biomedizin.unibas.ch links EBV to early MS-like lesion formation by showing how B cells can act at the very start of the disease process. 🔗 doi.org/10.1016/j.ce... @unibas.ch #EBV #MultipleSclerosis
Confocal micrograph of the mouse brain. The myelin sheaths that wrap the the axons of neurons are shown in red. The blue cells are infected with a virus. Such infections cause immune cells to enter the brain. If these immune cells attack the myelin, autoimmune disease can result. Image by Hyein Kim (University of Basel).
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 12/01/2026
Two back-to-back BJH papers from the XPAG-ITP trial! 🎉 ETB+dexamethasone showed longer response & less rescue therapy vs dex alone in ITP. Immune profiling reveals baseline TCR clonality predicts durable remission. 🔗 onlinelibrary.wiley.com/doi/10.1111/... #ITP #Hematology #TranslationalResearch
Artistic rendering of platelets and immune cells highlighting immune dynamics in immune thrombocytopenia. Generated with AI.
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 09/01/2026
How can we tell whether an antibiotic eradicates an infection? Researchers from the @biomedizin.unibas.ch, at the @unibas.ch, present an antimicrobial single-cell microscopy-based method that measures antibiotic lethality in individual bacteria. 🔗 doi.org/10.1038/s415... @natmicrobiol.nature.com
Some bacterial pathogens play dead to dodge antibiotics. A new test watches them closely—and helps choose drugs that finish the job. (Symbolic image: Adobe Stock)
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 23/12/2025
As we wrap up 2025, we’re wishing you peaceful days filled with rest, joy, and good company. 🌟 Thank you for being part of our community this year. Happy Holidays and all the very best for 2026 — from all of us at the @ biomedizin.unibas.ch ! #HappyHolidays #NewYear2026 #Biomedicine #UniBasel
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 18/11/2025
Our Tissue Engineering Lab has built the most advanced human bone marrow model! It supports blood cell formation, reduces the need for animal testing, and could one day aid drug testing and personalized cancer treatments. 👉 www.cell.com/cell-stem-ce... #TissueEngeneering #HumanBoneMarrowModel
Scanning electron microscopy image of the engineered 3D bone marrow tissue colonized with human blood cells (red). (Image: Andrés García García, University of Basel, Department of Biomedicine).
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 24/10/2025
New multicenter study from the RC2NB including members of the DBM shows granulocyte & astrocyte markers in CSF can clearly distinguish MOGAD and NMOSD from MS. 👉🏻 doi.org/10.1093/brai... #Neuroimmunology #MOGAD #NMOSD #MS #Biomarkers
Dynamic neural pathway simulation with flashing white patches highlighting demyelination (Image Adobe Stock).
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 22/10/2025
New findings in Science Translational Medicine reveal distinct immune signatures in MOGAD, distinguishing it from MS and pointing toward disease-specific therapies. Kudos to all involved. 👉🏻 www.science.org/doi/10.1126/... #MOGAD #Neuroinflammation #MSResearch
Visual representation of neuroinflammation: red, reactive immune activity disrupting the normal blue neural network. The image symbolizes the immune dysregulation underlying MOG antibody–associated disease (MOGAD).  Image Adobe Stock.
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 21/10/2025
Immune clues in tumors and blood predict who benefits from neoadjuvant chemoimmunotherapy in lung cancer. Congrats to the Zippelius Lab! www.nature.com/articles/s41... @nature.com #LungCancer #Immunotherapy #CancerResearch #Oncology #PrecisionMedicine
Microscopy images showing three separate areas of a lung tumor, representing different immune environments: desert, excluded, and inflamed. These are general examples used to illustrate how immune cells interact with tumors. The top row displays a CD8 immunohistochemistry image, while the bottom row shows a marked version where CD8+ T cells are highlighted in red and tumor cells in blue. Adopted from Schmid, D., et al. (2025), Nature Communications.
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 01/10/2025
🚀 Breakthrough in #ProstateCancer research from @biomedizin.unibas.ch published in @cp-cellreports.bsky.social! Matrigel-free PDOs preserve patient-specific cell populations. New single-cell atlas (PPScA) maps heterogeneity + reveals pathways altered in vitro.
Fluorescent microscopy image of antibody-labeled patient-derived organoids (PDOs), captured at Le Magnen Lab.
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 18/09/2025
Researchers @biomedizin.unibas.ch developed cartilage implants from nasal septum cells, and showed that allowing them to mature for two weeks improved outcomes. 🔬Congratulations to all contributors. doi.org/10.1126/scit... #Immunotherapy #CancerImmunology #FusionProtein #PD1IL2v #TCellTherapy
© Martin Oeggerli (www.Micronaut.ch) 2019-2025, with Marcel Philipp Trefny, and Prof. Alfred Zippelius, Cancer Immunology, University Hospital Basel, Pathology University Hospital Basel, and C-CINA, Biozentrum, University Basel
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 12/09/2025
New in Haematologica: Researchers at binderlab.bsky.social report a mutation-specific immunotherapy for high-risk CLL. A bispecific antibody (BiTE) redirects T cells to target IGLV3-21^R110+ leukemia cells—killing malignant cells while sparing healthy B cells. Link: doi.org/10.3324/haem...
Bispecific antibodies as a potential off-the-shelf immunotherapy for high-risk CLL patients (Image Adobe Stock)
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 04/09/2025
Four DBM researchers at the University of Basel just secured ERC Starting Grants!🎉 A huge congratulations to Jean-Christophe Beltra, Mariana Borsa @nanaborsa.bsky.social , Magdalena Sznurkowska & Tobias Weiss. 🔗 Full news: biomedizin.unibas.ch/en/communica... @erc.europa.eu #ERCStG
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 02/09/2025
🚀 Welcome Prof. Dr. Marc Aurel Busche @marcaurelbusche.bsky.social to the DBM, University of Basel! He’ll head the Brain Ageing & Neurodegeneration Lab, focusing on Alzheimer’s and brain circuit dysfunction. Read more: 🔗 biomedizin.unibas.ch/en/newsdetai...
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 25/08/2025
🎊Cheers to 25 Years of Discovery @biomedizin.unibas.ch ! Since 2000, we’ve grown into one of Switzerland’s top translational research hubs — thanks to our brilliant teams & community. We celebrated with music, laughter, science & soul. Here’s to the next 25.💙 biomedizin.unibas.ch/en/newsdetai...
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 21/08/2025
🏆 Dr. Laurentz Schuhknecht @zampierilab.bsky.social wins DBM Research Prize; Johanna Nimmerfroh (Läubli Lab) earns 1st Best Presentation Award at our Summer Symposium. Congratulations! 🎉 biomedizin.unibas.ch/en/communica... #DBMPrize #BestPresentationAward #ResearchExcellence
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 20/08/2025
The 2025 DBM Summer Symposium is happening today! There will be a keynote by Prof. Mustafa Khammash @eth-bsse.bsky.social , 17 short talks, and the presentation of the DBM Research Prize 2024 and the Best Presentation Award 2025. 🧬🏆 Big thanks to all involved! #DBMSymposium2025 #Science #TeamDBM
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 01/07/2025
🚀 We’re thrilled to welcome Prof. Dr. Valérie Hilgers (hilgerslab.bsky.social) to the DBM! She’ll head the RNA Biology & Neurogenetics Lab, investigating how RNA regulation drives brain development and function. ERC Consolidator Grant 2024 included. Read more: 🔗 biomedizin.unibas.ch/en/communica...
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 17/06/2025
Meet our Expert Jürg Schwaller from the Childhood Leukemia Lab at the @Department of Biomedicine. Today he shares his research and vision for AML treatment strategies. Read more in our Blog with our Expert. Blog with our Expert: biomedizin.unibas.ch/en/communica... #AML #Leukemia #Cancerresearch
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 06/06/2025
Big things are rising in Basel 🏗️ The new DBM building will bring researchers together under one roof, with a focus on collaboration, comfort, and climate-conscious design - a real boost for biomedical science in Switzerland. #ScienceForTheFuture #DBM #Basel
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 27/05/2025
The 10th Golden Edition of our DBM Newsletter is out now. 📰✨ A special printed copy was handed out at the 'Laying of the Foundation Stone Ceremony' on May 23 as a commemorative keepsake. Check it out here 👉 issuu.com/departementb... @biomedizin.unibas.ch #Newsletter #Research #TeamDBM
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 23/05/2025
🚧 Major milestone for the Department of Biomedicine: the foundation stone for the new DBM research building has been laid! A symbol of collaboration, innovation & sustainability, the new building is set to open in 2031. Read more: biomedizin.unibas.ch/en/newsdetai... #UniversityofBasel #DBM
Prof. Dr. Ivan Martin, Head of the Department of Biomedicine; Cantonal Councillor Mustafa Atici, Head of the Basel-Stadt Department of Education; Cantonal Councillor Monica Gschwind, Head of the Basel-Landschaft Department of Education, Culture and Sport; Dr. Rolf Borner, Director of Infrastructure & Operations at the University of Basel; Marc Brülhart, Head of Building Construction German-speaking Switzerland & Head of the Northwest Region Implenia; Dr. Beat Oberlin, President of the University Council of the University of Basel. (From left, photo: University of Basel, Christian Flierl)
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 01/04/2025
🚀 Thrilled to welcome Professor Dr. Pietro Cippà to the DBM team! As the new Professor of Nephrology at the University of Basel and Head of our Nephrology Lab, he’s set to drive transformative breakthroughs in kidney repair and transplant immunology. Read more: 🔗 biomedizin.unibas.ch/en/communica...
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 20/02/2025
🔬 Science works better when people work together! 26 researchers and core facility heads from @fmiscience.bsky.social & biomedizin.unibas.ch came together for a day of innovation and collaboration! The meeting covered a wide range of research areas and we're excited to see what comes next! 👏
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 13/02/2025
🔬 Key Regulators of Cell Fate Identified. Researchers from biomedizin.unibas.ch, embl.org & dkfz.bsky.social reveal that safeguard repressors like PROX1 can preserve cell identity & prevent liver cancer. Study by Aryan Kamal & Bryce Lim. 👉 🔗 www.nature.com/articles/s41... @naturegenet.bsky.social
Here, a puppeteer’s hands control the mountain ridges in Waddington’s illustration of cell fate commitment, adding another detail to our understanding of cell fate. Credit: Daniela Velasco/EMBL.
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 12/02/2025
🔬 AAV-Based Lymphocyte Depletion Reveals Key B Cell-CD8+ T Cell Synergy in Chronic Viral Infection as shown by Anna Lena Kastner (Pinschewer Lab biomedizin.unibas.ch) & colleagues. 🔗 Read more: www.cell.com/immunity/pdf... @cp-immunity.bsky.social #Immunology #AAV #Bcells #Tcells #ViralInfection
Durable Lymphocyte Subset Elimination to Decipher Immune Control of Chronic Viral Infection (Image: Adobe Stock, KI)
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 10/02/2025
Exciting news from the Apostolova lab @biomedizin.unibas.ch! A study by Petya Apostolova & Robert Zeiser shows extracorporeal photopheresis is effective in treating immune-related adverse events from checkpoint inhibitors. www.cell.com/cancer-cell/... #CancerResearch #Immunotherapy #ECP #ICI #irAE
In a collaborative effort, Petya Apostolova and colleagues found a way to combat immune-related adverse events during immune checkpoint inhibitor treatment, here shown in action. (Image: Adobe Stock, KI)
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 08/02/2025
Binder Lab: Immune Changes & Lymphoma Risk 🔬 DADA2 mutations disrupt immune balance—low antibodies, memory B/T loss & inflammation. binderlab.bsky.social links IGHV4-34 B cells to autoimmunity & lymphoma. Their ML tool detects DADA2 via immune architecture! 📖 More: www.jacionline.org/article/S009...
New Links Between Immune Dysfunction & Lymphoma Uncovered (Image: Adobe Stock, KI)
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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 04/02/2025
🔬 Welcome to the official Bluesky account of the Department of Biomedicine! 🧬✨ We explore recent discoveries in science, medicine, and innovation—sharing research, breakthroughs, and insights from our labs. Follow us for the latest updates! Watch the full video for more: youtu.be/w6Ln6BItaqI?...
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