iiinova — where your digital self keeps evolving

Intensive Care Medicine Journal @intenscaremed.bsky.social · 9h

Neurologic and systemic causes of death in severe meningitis and encephalitis follow distinct trajectories, with different associated factors and complications, as revealed by the international prospective EURECA study. rdcu.be/bm6JAfYFBGQa

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 05/10/2026

#VisualAbstract Failed weaning from invasive mechanical ventilation is not a single clinical entity, but comprises three distinct phenotypes. rdcu.be/djJio6McoF7a

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 04/10/2026

#VisualAbstract A higher hemoglobin transfusion threshold offered no clear advantage in cancer patients with septic shock and was associated with more thrombotic events. rdcu.be/JXfQ9R7dycVa

001

Intensive Care Medicine Journal @intenscaremed.bsky.social · 03/10/2026

#VisualAbstract Adding multiplex PCR to conventional microbiology did not significantly increase targeted antimicrobial therapy at 24 hours in patients with suspected ventilator-associated or ventilated hospital-acquired pneumonia. rdcu.be/RVPgx5LzR1Ma

111

Intensive Care Medicine Journal @intenscaremed.bsky.social · 02/10/2026

This editorial discusses ICU access for acute leukemia patients, highlighting improved outcomes and factors influencing care. rdcu.be/9xKotd7MeM5a

010

Intensive Care Medicine Journal @intenscaremed.bsky.social · 01/10/2026

#VisualAbstract Trauma-related ARDS results from direct injury, systemic inflammation and resuscitation factors, and care relies on early risk stratification, multimodal imaging, pain control and individualized respiratory support. doi.org/10.1007/s001...

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 30/09/2026

#VisualAbstract β-blocker therapy in critical illness has established benefits in selected conditions, but remains context-dependent because efficacy and safety vary with indication, timing, haemodynamic reserve and patient phenotype. rdcu.be/cUR92Yhikvwa

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 29/09/2026

A phase 2 trial found that ilofotase alfa was safe but did not prevent kidney injury in high-risk patients after open heart surgery. rdcu.be/wNCkJQqH9G5a

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 27/09/2026

#VisualAbstract ARDS and acute brain injury require individualised ventilation that balances lung protection with cerebral physiology and neuromonitoring. doi.org/10.1007/s001...

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 26/09/2026

#VisualAbstract Temporal trends in critical care burden and outcomes of Andes virus-associated hantavirus cardiopulmonary syndrome in a national Chilean cohort were assessed. rdcu.be/6FvuFR2ZXYYa

010

Intensive Care Medicine Journal @intenscaremed.bsky.social · 25/09/2026

Post-intensive care syndrome (PICS) is a growing consequence of critical illness, affecting patients, families, and professionals across the recovery continuum. doi.org/10.1007/s001...

020

Intensive Care Medicine Journal @intenscaremed.bsky.social · 24/09/2026

Failed weaning from invasive mechanical ventilation is not a single clinical entity, but comprises three distinct phenotypes. rdcu.be/djJio6McoF7a

011

Intensive Care Medicine Journal @intenscaremed.bsky.social · 23/09/2026

#VisualAbstract ECLS has evolved from rescue therapy to established care for selected patients with severe ARDS, while ECCO₂R remains limited by uncertain benefit and safety concerns. rdcu.be/fszcS

011

Intensive Care Medicine Journal @intenscaremed.bsky.social · 22/09/2026

#VisualAbstract A new acute kidney injury reporting framework sets specific standards to improve the quality, comparability, and clinical use of biomarker diagnostic accuracy studies. doi.org/10.1007/s001...

010

Intensive Care Medicine Journal @intenscaremed.bsky.social · 20/09/2026

Sepsis-associated liver injury is a complex condition, and routine liver tests can help identify patients at risk for deterioration. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 20/09/2026

Adding multiplex PCR to conventional microbiology did not significantly increase targeted antimicrobial therapy at 24 hours in patients with suspected ventilator-associated or ventilated hospital-acquired pneumonia. Link in the first comment.

001

Intensive Care Medicine Journal @intenscaremed.bsky.social · 19/09/2026

Temporal trends in critical care burden and outcomes of Andes virus-associated hantavirus cardiopulmonary syndrome in a national Chilean cohort were assessed. Link in the first comment.

010

Intensive Care Medicine Journal @intenscaremed.bsky.social · 19/09/2026

The Surviving Sepsis Campaign now aims to align sepsis care with patient goals beyond mere survival, focussing on quality of life and meaningful recovery. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 18/09/2026

#VisualAbstract Lung- and diaphragm-protective ventilation in acute respiratory distress syndrome integrates lung stress control with preservation of appropriate respiratory effort. Link in the first comment.

010

Intensive Care Medicine Journal @intenscaremed.bsky.social · 18/09/2026

Hypernatremia is common in critically ill patients, associated with increased mortality, and requires thorough evaluation of fluid status, electrolytes, and urine chemistry for effective management. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 17/09/2026

Randomised trials have shifted intensive care from universal physiological correction towards calibrated, context-sensitive care that weighs benefit, harm, timing, heterogeneity and recovery. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 17/09/2026

Diagnostic errors affect about 10–25% of critically ill patients and arise from interacting human and system factors that can lead to delayed, missed, incorrect diagnoses or overdiagnosis. Link in the first comment.

100

Intensive Care Medicine Journal @intenscaremed.bsky.social · 16/09/2026

Trauma-related ARDS results from direct injury, systemic inflammation and resuscitation factors, and care relies on early risk stratification, multimodal imaging, pain control and individualized respiratory support. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 16/09/2026

#VisualAbstract High-flow nasal cannula oxygen during breaks from noninvasive ventilation may reduce extubation failure in high-risk patients, although adjusted analysis did not confirm the unadjusted findings. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 15/09/2026

A higher hemoglobin transfusion threshold offered no clear advantage in cancer patients with septic shock and was associated with more thrombotic events. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 15/09/2026

Adjuvant therapies for acute respiratory distress syndrome complement mechanical ventilation by reducing lung injury and improving patient outcomes. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 14/09/2026

#VisualAbstract Critical illness changes antiseizure medication exposure, requiring tailored selection, dosing, and monitoring in intensive care. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 14/09/2026

In adults with septic shock, vasopressin started within 0–3 hours after norepinephrine escalation was associated with lower 28-day mortality than initiation after 3–6 hours. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 13/09/2026

#VisualAbstract Persistent tissue hypoperfusion combined with vasopressor dose improved risk stratification in early septic shock and identified a small subgroup with markedly increased 28-day mortality. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 13/09/2026

Clinical metagenomics can identify bacteria, viruses, fungi and parasites in one test, with rapid local methods also providing antimicrobial resistance, virulence and strain information within hours. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 12/09/2026

ARDS management can extend guideline-based lung protection through physiology-driven adjustment of ventilation, PEEP, hemodynamics and respiratory effort to each patient’s characteristics and treatment response. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 12/09/2026

Automated cuff pressure control with continuous subglottic secretion drainage lowered microbiologically documented VAP, but not day-3 tracheobronchial colonization, antibiotic use or mortality. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 11/09/2026

Respiratory system elastance may help individualize tidal volume and respiratory rate in mechanically ventilated patients with acute brain injury. Link in the first comment.

001

Intensive Care Medicine Journal @intenscaremed.bsky.social · 11/09/2026

Persistent inflammation, immunosuppression, and catabolism syndrome can follow major acute insults and is associated with recurrent infections, poor wound healing, muscle wasting, functional decline, and death. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 10/09/2026

#VisualAbstract Rehabilitation after critical illness in patients with obesity requires early, tailored respiratory care, nutrition, mobilisation, appropriate equipment and structured post-ICU follow-up. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 10/09/2026

Future pandemic resilience depends on better measurement, workforce protection, regional coordination, adaptable capacity and equitable critical care. Link in the first comment.

010

Intensive Care Medicine Journal @intenscaremed.bsky.social · 09/09/2026

Corticosteroid benefit in ARDS varies with etiology, disease stage, inflammatory phenotype, and timing of administration. Link in the first comment.

100

Intensive Care Medicine Journal @intenscaremed.bsky.social · 09/09/2026

Early non-invasive ventilation reduced endotracheal intubation and ICU admission in adults with acute respiratory failure treated before ICU admission. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 08/09/2026

Protocolized early mobilization did not improve functional status at ICU discharge or 1 year compared with conventional physiotherapy. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 08/09/2026

AI in intensive care could combine reinforcement learning with adaptive randomisation to support treatment decisions while preserving opportunities to learn when uncertainty remains. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 07/09/2026

#VisualAbstract Prone positioning improves oxygenation, reduces lung stress and strain, and lowers mortality when applied early for prolonged sessions in selected intubated patients with moderate-to-severe acute respiratory distress syndrome. Link in the first comment.

010

Intensive Care Medicine Journal @intenscaremed.bsky.social · 07/09/2026

Serious news can trigger rapid emotional and stress responses that narrow attention, impair memory, and limit understanding during clinical conversations. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 06/09/2026

β-blocker therapy in critical illness has established benefits in selected conditions, but remains context-dependent because efficacy and safety vary with indication, timing, haemodynamic reserve and patient phenotype. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 05/09/2026

Esophageal pressure monitoring can separate lung and chest wall pressures during ARDS ventilation, but evidence has not confirmed consistent benefits for mortality or days ventilated. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 04/09/2026

#VisualAbstract Intracranial hypertension after acute brain injury requires interpretation beyond fixed pressure thresholds, using physiological context and multimodal neuromonitoring to support individualized management. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 03/09/2026

Shock can desensitize cardiovascular adrenoceptors and impair intracellular signalling, contributing to catecholamine resistance and increasing the need for high vasopressor doses. Link in the first comment.

100

Intensive Care Medicine Journal @intenscaremed.bsky.social · 02/09/2026

ARDS and acute brain injury require individualised ventilation that balances lung protection with cerebral physiology and neuromonitoring. Link in the first comment.

000

Intensive Care Medicine Journal @intenscaremed.bsky.social · 01/09/2026

Machine learning models predicted disease severity and mortality in secondary hemophagocytic lymphohistiocytosis, but external validation remains essential. Link in the first comment.

010

Intensive Care Medicine Journal @intenscaremed.bsky.social · 17/08/2026

Intensive care innovation can include architectural redesign that supports family engagement, natural light and a better care experience while generating measurable value. zurl.co/sjxt9

012

Intensive Care Medicine Journal @intenscaremed.bsky.social · 16/08/2026

#VisualAbstract Prehospital airway and ventilatory management requires timely intubation, physiology optimization, structured rescue pathways and cautious use of non-invasive respiratory support. zurl.co/343ek

000