This study identifies ANTXR2 as the cellular receptor for Clostridium perfringens toxin NetF and determines its structure bound to the toxin using cryo-EM, revealing a distinct lateral binding mechani...

Wang et al. present an optimized labeling strategy for cryo-electron tomography based on genetically encoded FerriTag. This system uses rapamycin to recruit iron-loaded ferritin to target proteins, en...

This study explores how cryo-electron microscopy (cryo-EM) can be used to image large areas of frozen biological samples with near-atomic resolution. The researchers used a method called CEMOVIS, whic...

Vitreous sectioning (CEMOVIS) is an alternative to FIB milling for generating thin samples suitable for cryo-EM imaging. We show that CEMOVIS samples preserve the high-resolution structural details of...

The phosphotransferase system glucose-specific transporter IICBGlc serves as a central nutrient uptake system in bacteria. It transports glucose acros…

Aerolysin is a β-pore-forming toxin produced by most Aeromonas bacteria, which has attracted large attention in the field of nanopore sensing due to its narrow and charged pore lumen. Structurally sim...