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Bruce Hamilton

@bahome.bsky.social
1.8K followers 871 following 884 posts

Professor, personal account. Genetics, genomics, brain development, other stuff. Typo-prone. If you’re nice I’ll post dog photos.

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Bruce Hamilton @bahome.bsky.social · 54m
Blast from the past timeline cleanse.
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Bruce Hamilton @bahome.bsky.social · 55m
Yeet.
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Bruce Hamilton @bahome.bsky.social · 1h
Too quick. Ethylnitrosourea.
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Bruce Hamilton @bahome.bsky.social · 6h
Do it.
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Joshua Weitz @joshuasweitz.bsky.social · 11/10/2026
The NIH proposal to conceal reviewer scores from program officers, investigators, and advisory councils is ill-conceived, introduces disproportionate weight to small percentile differences, diminishes the role of scientific peer review, and should be withdrawn in its entirety. a 🧵
joshuasweitz.substack.com
What is NIH Leadership Trying to Hide from Researchers & the Public?
A NIH proposal to conceal reviewer rankings of investigator-initiated research grants is ripe for misuse & demands a collective response (by October 13).
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Bruce Hamilton @bahome.bsky.social · 11/10/2026
The One Minute Assistant Manager.
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Bruce Hamilton @bahome.bsky.social · 11/10/2026
Ruin a book by adding a word to the title: Getting to Yes Man
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Bruce Hamilton @bahome.bsky.social · 11/10/2026
Ruin a book by adding a word: Moby Dick Clark
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Bruce Hamilton @bahome.bsky.social · 11/10/2026
With high probability,
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Bruce Hamilton @bahome.bsky.social · 11/10/2026
May he soon win a very tremendous Darwin Award.
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George Wallace @mrgeorgewallace.bsky.social · 10/10/2026
Real talk? The wockaflockas banning 12,000 books and broadcasting executions are rarely the good guys and whatnot.
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Bruce Hamilton @bahome.bsky.social · 10/10/2026
I wish to thank those long-ago reviewers for being really smart.
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Bruce Hamilton @bahome.bsky.social · 10/10/2026
I had Geoff read the specific aims of my first grant. He read it in front of me, shook his head, and said, “You’re going to need some really smart reviewers.” “Should I rewrite it?” “No. But you’re going to need some really smart reviewers.”
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Bruce Hamilton @bahome.bsky.social · 10/10/2026
Submit your comments through the link in quoted post below. Here are mine:
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Bruce Hamilton @bahome.bsky.social · 10/10/2026
This looks cool. GxE with modifiers.
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National Weather Service @nws.noaa.gov · 09/10/2026
There is another tropical system set to impact the West Coast. Tropical Storm #Rachel will be approaching southern California later this weekend. Tropical Storm Watches have been issued for southern California. Get the latest at hurricanes.gov and weather.gov.
Note: The cone contains the probable path of the storm center but does not show the size of the storm. Hazardous conditions can occur outside of the cone.   Details & Current Information:Storm: Tropical Storm Rachel   Date & Time: Friday October 09, 2026, 8 AM PDT Advisory 50   Issuer: NWS National Hurricane Center   Center Location: $22.8^\circ\text{N}, 124.6^\circ\text{W}$   Max Sustained Wind: 50 mph   Movement: NE at 5 mph   Forecast Positions:8 AM Fri: Tropical Storm ('S')   5 AM Sat / 5 PM Sat / 5 AM Sun / 5 PM Sun: Tropical Storm ('S')   Watches & Warnings:Tropical Storm Watch (Yellow): Baja California Peninsula coast and Southern California coastline   Map Description:
Forecast cone showing Tropical Storm Rachel moving northeast from the Eastern Pacific toward the northern Baja California Peninsula and Southern California/Nevada region.  Tropical Storm Watch vs. Tropical Storm Warning

   
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Tropical Storm Watch (Yellow):

   
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A Tropical Storm Watch is issued when tropical storm conditions are possible, typically within 48 hours.

   
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Prepare your home by securing loose items outside or moving them indoors. Have an emergency supply kit ready and charge your devices.   
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Tropical Storm Winds Possible.

   
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Tropical Storm Warning (Blue):

   
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A Tropical Storm Warning is issued when tropical storm conditions are expected, typically within 36 hours.

   
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Follow the advice of local officials and be ready to seek shelter in a sturdy structure.   
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Tropical Storm Winds Expected!
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Bruce Hamilton @bahome.bsky.social · 09/10/2026
⬆️ Really good book
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Bruce Hamilton @bahome.bsky.social · 08/10/2026
Che Tranberries
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Bruce Hamilton @bahome.bsky.social · 08/10/2026
And I accept that.
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Bruce Hamilton @bahome.bsky.social · 08/10/2026
“Consistency is contrary to nature, contrary to life. The only completely consistent people are the dead” Aldous Huxley
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Kevin Plaxco @kwplaxco.bsky.social · 07/10/2026
I once received funding from an ARO program that a PM there created based on his own work. The first four words of his foundational paper were "DNA and other proteins." We did good science with the money, which I suppose helps? Eventually he went to jail for embezzlement. The End.
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Bruce Hamilton @bahome.bsky.social · 07/10/2026
Also, the Molecular Biology exam I graded as a TA way (way) back, in which a student had responded to what is a promoter? with: “The promoter is the part of the ribosome that binds DNA.”
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Bruce Hamilton @bahome.bsky.social · 07/10/2026
“And the amino acids in DNA” made me think of this:
static.klipy.com
Animal House: Bluto's Pearl Harbor Quote
ALT: Animal House: Bluto's Pearl Harbor Quote
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Nobel Prize @nobelprize.org · 07/10/2026
This year’s Nobel Prize laureate in chemistry Henri B. Kagan was born in 1930 in Boulogne-Billancourt, France. He earned his PhD in 1960 from Collège de France, France. He is professor emeritus at Université Paris-Sud, now known as @univparissaclay.bsky.social
Henri B. Kagan
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Nobel Prize @nobelprize.org · 07/10/2026
Kenso Soai, awarded the 2026 Nobel Prize in Chemistry, was born in 1950 in Hiroshima, Japan. He earned his PhD in 1979 from the University of Tokyo, Japan. He is professor emeritus at Tokyo University of Science, Japan.
Kenso Soai
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Bruce Hamilton @bahome.bsky.social · 07/10/2026
A+ reporting on the chemistry Nobels by the New York Times. </src>
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Richard Sever @richardsever.bsky.social · 03/10/2026
Any sane academic evaluation policy would forbid mention of Impact Factor
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Bruce Hamilton @bahome.bsky.social · 05/10/2026
Olympic National Park, 2026
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Bruce Hamilton @bahome.bsky.social · 05/10/2026
MLB: We do not tolerate gambling. Also MLB: Here is a firehose of ads for gambling.
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Bruce Hamilton @bahome.bsky.social · 02/10/2026
Worth zooming in
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Bruce Hamilton @bahome.bsky.social · 01/10/2026
Happy for Will Venable. And the Pope. #baseball
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Bruce Hamilton @bahome.bsky.social · 30/09/2026
youtu.be/1rP-U-ZbuzE?...
youtu.be
7 Words Extended Version | George Carlin | Again! (1978)
YouTube video by Official George Carlin
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Bruce Hamilton @bahome.bsky.social · 30/09/2026
What? No! Famously, there are seven words.
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Bruce Hamilton @bahome.bsky.social · 30/09/2026
⬇️⬇️⬇️⬇️⬇️⬇️⬇️⬇️
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Bruce Hamilton @bahome.bsky.social · 30/09/2026
So much policy argument is spent justifying post hoc the preferences that one’s in-group has already selected for their direct benefit. Here I show from first principles that actual population-wide policy optima can be empirically identified by what benefits large white dogs. 1/
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Django Wexler @djangowexler.bsky.social · 28/09/2026
Animals are really a great analogy, we have a legal construct already for "thing that you own which behaves unpredictably" and the standard is "you are responsible for the damage it causes so make sure you restrain it appropriately."
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Alon Goren @agoren.bsky.social · 29/09/2026
1/2 I’m excited to share @edumodolo.bsky.social’s preprint: Discrepancies between ChIP-seq and CUT&Tag histone mark profiles are explained by GC content and chromatin accessibility. www.biorxiv.org/content/10.6...
biorxiv.org
Discrepancies between ChIP-seq and CUT&amp;Tag histone mark profiles are explained by GC content and chromatin accessibility
Chromatin profiling methods, such as ChIP-seq (chromatin immunoprecipitation followed by sequencing), are used to characterize the genomic localization of DNA-associated proteins. While ChIP and ChIP-...
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/09/2026
For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu
Front page of the website
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Bruce Hamilton @bahome.bsky.social · 28/09/2026
Yup
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Bruce Hamilton @bahome.bsky.social · 28/09/2026
static.klipy.com
A Clockwork Orange: Alex's Ludovico Technique
ALT: A Clockwork Orange: Alex's Ludovico Technique
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Bruce Hamilton @bahome.bsky.social · 28/09/2026
It’s like publishing the rough draft of a bad novel on a collection of advertising spaces in Times Square.
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Bruce Hamilton @bahome.bsky.social · 28/09/2026
Online training module put so much effort on fonts and layouts that might better have gone to ideas and complete sentences.
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Stephen Davey @stephengdavey.bsky.social · 28/09/2026
PSA: It is statistically illiterate to claim that you are receiving higher than average call volumes 100% of the time.
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Bruce Hamilton @bahome.bsky.social · 27/09/2026
Uphill both ways.
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Bruce Hamilton @bahome.bsky.social · 27/09/2026
static.klipy.com
Princess Bride: When I Was Your Age
ALT: Princess Bride: When I Was Your Age
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Bruce Hamilton @bahome.bsky.social · 26/09/2026
Lethal Giant Larvae Pyroptosis
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BWJones @bwjones.bsky.social · 25/09/2026
Science peeps: Looks like SciENcv updated the digital certificate used to sign Biosketch and Current & Pending documents without notification. The old certificate expires Saturday, September 26, 2026. SciENcv docs before that date may fail validation in eRA Commons delaying or blocking submission.
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Bruce Hamilton @bahome.bsky.social · 25/09/2026
Had to take a sick day. Tried to do some mandatory online training modules. May get well from sheer boredom.
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allen institute @alleninstitute.org · 17/09/2026
Deep in the brain’s “blue place,” our scientists found something surprising: a tiny brain region once thought to broadcast one signal actually sends targeted messages through distinct routes, including via the longest neuron ever measured in a mouse.
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Jeremy Berg @jeremymberg.bsky.social · 31/05/2025
For those who don't know Randy Pausch, he was a computer scientist who gave "The Last Lecture" at CMU when he had terminal pancreatic cancer. Lots of inspiration and life lesson. Worth the time to give it a watch (whether or not you have done so in the past. www.youtube.com/watch?v=ji5_...
youtube.com
Randy Pausch Last Lecture: Achieving Your Childhood Dreams
YouTube video by Carnegie Mellon University
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