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Christopher Azaldegui

@azaldegui.bsky.social
36 followers 58 following 0 posts

Postdoc @ Stanford University freezing bugs and shooting lasers at them

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Reposted by Christopher Azaldegui
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 24/07/2026
A self-organized geometry sensing oscillator spatially regulates cell division in archaea www.biorxiv.org/content/10.64898/20…
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Reposted by Christopher Azaldegui
Scott Coyle @cellraiser.bsky.social · 16/06/2026
Sub-cellular architectures arise through integrating signaling and structure. @edenchang.bsky.social and @zjmaggiexu.bsky.social show how coupling reaction-diffusion signaling to protein condensation provides a tunable, regulatable landscape for sub-cellular structure www.biorxiv.org/content/10.6...
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Reposted by Christopher Azaldegui
Julie Biteen @juliebiteenlab.bsky.social · 26/05/2026
We enjoyed putting our heads together with the Jakob and Freddolino labs to find that polyphosphate modulates the formation of functional RNA-protein condensates in response to nitrogen-starvation stress! journals.plos.org/plosbiology/...
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Reposted by Christopher Azaldegui
Julie Biteen @juliebiteenlab.bsky.social · 06/03/2026
In the context of carboxysome positioning, @azaldegui.bsky.social found that the aggregation of a bacterial microcompartment is prevented by a self-organizing DNA-binding ATPase! #SingleMolecule #SuperResolution #Microscopy with @cellforganized.bsky.social and JianLiu doi.org/10.64898/202...
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Reposted by Christopher Azaldegui
Julie Biteen @juliebiteenlab.bsky.social · 20/02/2026
Xiaofeng combined 2D live-cell single-particle tracking with 3D simulations to specifically measure the bacterial nucleoid accessibility and viscosity! Our preprint describes how these nucleoid properties respond to cellular processes! Code is available too. www.biorxiv.org/content/10.6...
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Reposted by Christopher Azaldegui
Julie Biteen @juliebiteenlab.bsky.social · 15/01/2026
Now published in Protein Science: Dan used single-molecule and SOFI microscopies to visualize curli fibers (the major component of E. coli biofilms) on living cells! onlinelibrary.wiley.com/doi/10.1002/...
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Reposted by Christopher Azaldegui
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 19/11/2025
Equipositioning of Chromosomes in the Polyploid Archaeon Haloferax volcanii by HpaAB www.biorxiv.org/content/10.1101/202…
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Reposted by Christopher Azaldegui
Julie Biteen @juliebiteenlab.bsky.social · 14/11/2025
Now in print: @lortzrodz.bsky.social with @schraderlab.bsky.social found that the stress-induced transition of the material properties of bacterial ribonucleoprotein bodies repurposes them from sites of mRNA decay to reservoirs for mRNA storage. @natcomms.nature.com www.nature.com/articles/s41...
nature.com
Stress changes the material state of a bacterial biomolecular condensate and shifts its function from mRNA decay to storage - Nature Communications
Bacterial ribonucleoprotein bodies are dynamic biomolecular condensates that play roles in RNA metabolism. Here, Ortiz-Rodríguez et al. show that, under stress, these condensates shift from a liquid s...
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Reposted by Christopher Azaldegui
Anthony Vecchiarelli @cellforganized.bsky.social · 23/09/2025
New PrePrint from the Vecchiarelli and Mosalaganti (@shyamalm.bsky.social) labs! 🧵 Collaboration with the Giessen and Pi labs Congratulations to co-first authors Y Hoang (@hoanghamyy.bsky.social) and Pankaj Jadhav! www.biorxiv.org/content/10.1...
biorxiv.org
Engineering Spatial Control of Bacterial Organelles
Bacteria were once thought to lack organelles, but it is now clear they confine cellular reactions using an array of membrane- and protein-based compartments. A central question, however, is how bacte...
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Reposted by Christopher Azaldegui
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 23/09/2025
Engineering Spatial Control of Bacterial Organelles www.biorxiv.org/content/10.1101/202…
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Reposted by Christopher Azaldegui
bioRxiv Biophysics @biorxiv-biophys.bsky.social · 21/09/2025
Interferometric Image Scanning Microscopy for label-free imaging at 120 nm resolution inside live cells www.biorxiv.org/content/10.1101/202…
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Reposted by Christopher Azaldegui
bioRxiv Biophysics @biorxiv-biophys.bsky.social · 05/09/2025
Dps binds and protects DNA in starved Escherichia coli with minimal effect on chromosome accessibility, dynamics and organisation www.biorxiv.org/content/10.1101/202…
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Reposted by Christopher Azaldegui
Anthony Vecchiarelli @cellforganized.bsky.social · 30/05/2025
New @biorxiv-microbiol.bsky.social PrePrint from the Vecchiarelli Lab! 🧵 In collaboration with Jian Liu's lab at Johns Hopkins doi.org/10.1101/2025... Congratulations to first author Jordan Byrne! @sickbyrne.bsky.social P.S. She is looking for jobs! Pls ReSkeet
doi.org
Tuning the interaction of a ParA-type ATPase with its partner separates bacterial organelle positioning from partitioning
The maintenance of carboxysome distribution (Mcd) system comprises the proteins McdA and McdB, which spatially organize carboxysomes to promote efficient carbon fixation and ensure their equal inherit...
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Reposted by Christopher Azaldegui
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 23/05/2025
Tuning the interaction of a ParA-type ATPase with its partner separates bacterial organelle positioning from partitioning www.biorxiv.org/content/10.1101/202…
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Reposted by Christopher Azaldegui
Julie Biteen @juliebiteenlab.bsky.social · 04/05/2025
The hooding ceremony was a chance to celebrate these 2024 🎓 graduates all over again!
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Reposted by Christopher Azaldegui
Anthony Vecchiarelli @cellforganized.bsky.social · 25/04/2025
New @biorxiv-microbiol.bsky.social Pre-Print from the Vecchiarelli Lab! 🧵 doi.org/10.1101/2025... Congratulations to first author Claire Dudley! @claire-dudley.bsky.social Pls ReSkeet
pubs.acs.org
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