Reposted by Christopher AzaldeguibioRxiv Microbiology @biorxiv-microbiol.bsky.social · 24/07/2026A self-organized geometry sensing oscillator spatially regulates cell division in archaea www.biorxiv.org/content/10.64898/20… 056
Reposted by Christopher AzaldeguiScott Coyle @cellraiser.bsky.social · 16/06/2026Sub-cellular architectures arise through integrating signaling and structure. @edenchang.bsky.social and @zjmaggiexu.bsky.social show how coupling reaction-diffusion signaling to protein condensation provides a tunable, regulatable landscape for sub-cellular structure www.biorxiv.org/content/10.6... 24323
Reposted by Christopher AzaldeguiJulie Biteen @juliebiteenlab.bsky.social · 26/05/2026We enjoyed putting our heads together with the Jakob and Freddolino labs to find that polyphosphate modulates the formation of functional RNA-protein condensates in response to nitrogen-starvation stress! journals.plos.org/plosbiology/... 0188
Reposted by Christopher AzaldeguiJulie Biteen @juliebiteenlab.bsky.social · 06/03/2026In the context of carboxysome positioning, @azaldegui.bsky.social found that the aggregation of a bacterial microcompartment is prevented by a self-organizing DNA-binding ATPase! #SingleMolecule #SuperResolution #Microscopy with @cellforganized.bsky.social and JianLiu doi.org/10.64898/202... 0154
Reposted by Christopher AzaldeguiJulie Biteen @juliebiteenlab.bsky.social · 20/02/2026Xiaofeng combined 2D live-cell single-particle tracking with 3D simulations to specifically measure the bacterial nucleoid accessibility and viscosity! Our preprint describes how these nucleoid properties respond to cellular processes! Code is available too. www.biorxiv.org/content/10.6... 03214
Reposted by Christopher AzaldeguiJulie Biteen @juliebiteenlab.bsky.social · 15/01/2026Now published in Protein Science: Dan used single-molecule and SOFI microscopies to visualize curli fibers (the major component of E. coli biofilms) on living cells! onlinelibrary.wiley.com/doi/10.1002/... 062
Reposted by Christopher AzaldeguibioRxiv Microbiology @biorxiv-microbiol.bsky.social · 19/11/2025Equipositioning of Chromosomes in the Polyploid Archaeon Haloferax volcanii by HpaAB www.biorxiv.org/content/10.1101/202… 099
Reposted by Christopher AzaldeguiJulie Biteen @juliebiteenlab.bsky.social · 14/11/2025Now in print: @lortzrodz.bsky.social with @schraderlab.bsky.social found that the stress-induced transition of the material properties of bacterial ribonucleoprotein bodies repurposes them from sites of mRNA decay to reservoirs for mRNA storage. @natcomms.nature.com www.nature.com/articles/s41...nature.comStress changes the material state of a bacterial biomolecular condensate and shifts its function from mRNA decay to storage - Nature CommunicationsBacterial ribonucleoprotein bodies are dynamic biomolecular condensates that play roles in RNA metabolism. Here, Ortiz-Rodríguez et al. show that, under stress, these condensates shift from a liquid s... 1167
Reposted by Christopher AzaldeguiAnthony Vecchiarelli @cellforganized.bsky.social · 23/09/2025New PrePrint from the Vecchiarelli and Mosalaganti (@shyamalm.bsky.social) labs! 🧵 Collaboration with the Giessen and Pi labs Congratulations to co-first authors Y Hoang (@hoanghamyy.bsky.social) and Pankaj Jadhav! www.biorxiv.org/content/10.1...biorxiv.orgEngineering Spatial Control of Bacterial OrganellesBacteria were once thought to lack organelles, but it is now clear they confine cellular reactions using an array of membrane- and protein-based compartments. A central question, however, is how bacte... 24525
Reposted by Christopher AzaldeguibioRxiv Microbiology @biorxiv-microbiol.bsky.social · 23/09/2025Engineering Spatial Control of Bacterial Organelles www.biorxiv.org/content/10.1101/202… 001
Reposted by Christopher AzaldeguibioRxiv Biophysics @biorxiv-biophys.bsky.social · 21/09/2025Interferometric Image Scanning Microscopy for label-free imaging at 120 nm resolution inside live cells www.biorxiv.org/content/10.1101/202… 043
Reposted by Christopher AzaldeguibioRxiv Biophysics @biorxiv-biophys.bsky.social · 05/09/2025Dps binds and protects DNA in starved Escherichia coli with minimal effect on chromosome accessibility, dynamics and organisation www.biorxiv.org/content/10.1101/202… 011
Reposted by Christopher AzaldeguiAnthony Vecchiarelli @cellforganized.bsky.social · 30/05/2025New @biorxiv-microbiol.bsky.social PrePrint from the Vecchiarelli Lab! 🧵 In collaboration with Jian Liu's lab at Johns Hopkins doi.org/10.1101/2025... Congratulations to first author Jordan Byrne! @sickbyrne.bsky.social P.S. She is looking for jobs! Pls ReSkeetdoi.orgTuning the interaction of a ParA-type ATPase with its partner separates bacterial organelle positioning from partitioningThe maintenance of carboxysome distribution (Mcd) system comprises the proteins McdA and McdB, which spatially organize carboxysomes to promote efficient carbon fixation and ensure their equal inherit... 1138
Reposted by Christopher AzaldeguibioRxiv Microbiology @biorxiv-microbiol.bsky.social · 23/05/2025Tuning the interaction of a ParA-type ATPase with its partner separates bacterial organelle positioning from partitioning www.biorxiv.org/content/10.1101/202… 169
Reposted by Christopher AzaldeguiJulie Biteen @juliebiteenlab.bsky.social · 04/05/2025The hooding ceremony was a chance to celebrate these 2024 🎓 graduates all over again! 0101
Reposted by Christopher AzaldeguiAnthony Vecchiarelli @cellforganized.bsky.social · 25/04/2025New @biorxiv-microbiol.bsky.social Pre-Print from the Vecchiarelli Lab! 🧵 doi.org/10.1101/2025... Congratulations to first author Claire Dudley! @claire-dudley.bsky.social Pls ReSkeetpubs.acs.org 1136