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Luis A. Ortiz-Rodríguez, PhD

@lortzrodz.bsky.social
78 followers 170 following 0 posts

Pioneer Postdoctoral Fellow at UM | Measuring Subcellular Interactions and Material State Impact on Bacterial Biomolecular Condensates Using Single-Molecule Methods in the Biteen Lab @juliebiteenlab.bsky.social He/Him

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Reposted by Luis A. Ortiz-Rodríguez, PhD
Julie Biteen @juliebiteenlab.bsky.social · 28/11/2025
@lortzrodz.bsky.social's manuscript was featured as a @natcomms.nature.com Editors' Highlight! Read more about this functional change in the material state of bacterial condensates: doi.org/10.1038/s414... , and see the rest of the collection at: www.nature.com/collections/...
nature.com
Microbiology and infectious diseases
This page highlights recent articles on all aspects of bacteriology, mycology, parasitology and virology, covering the biology of pathogens, host-pathogen ...
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Reposted by Luis A. Ortiz-Rodríguez, PhD
Julie Biteen @juliebiteenlab.bsky.social · 14/11/2025
Now in print: @lortzrodz.bsky.social with @schraderlab.bsky.social found that the stress-induced transition of the material properties of bacterial ribonucleoprotein bodies repurposes them from sites of mRNA decay to reservoirs for mRNA storage. @natcomms.nature.com www.nature.com/articles/s41...
nature.com
Stress changes the material state of a bacterial biomolecular condensate and shifts its function from mRNA decay to storage - Nature Communications
Bacterial ribonucleoprotein bodies are dynamic biomolecular condensates that play roles in RNA metabolism. Here, Ortiz-Rodríguez et al. show that, under stress, these condensates shift from a liquid s...
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Reposted by Luis A. Ortiz-Rodríguez, PhD
Ákos T Kovács @evolvedbiofilm.bsky.social · 07/06/2025
A general mechanism for initiating the bacterial general stress response #Bacillussubtilis #RsbT #RsbU -in #eLIFE elifesciences.org/articles/100...
elifesciences.org
A general mechanism for initiating the bacterial general stress response
A coiled-coil-based transduction mechanism is identified for a serine/threonine phosphatase that controls a bacterial stress response, suggesting that phosphatases are part of a modularly exchangeable...
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Reposted by Luis A. Ortiz-Rodríguez, PhD
Anna-Karin Gustavsson @gustavssonlab.bsky.social · 23/11/2024
Our review on Light sheet illumination in single-molecule localization microscopy for imaging of cellular architectures and molecular dynamics is now published in npj Imaging! Check it out here: doi.org/10.1038/s443...
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Reposted by Luis A. Ortiz-Rodríguez, PhD
Lydia Kisley @lydia-kisley.bsky.social · 19/11/2024
Wednesday at 4:30 in Clapp 108! Come join us for a biophysics colloquium colloquium from @lortzrodz.bsky.social We're looking forward to welcoming him back to CWRU & learning more about RNA regulation in bacteria via phase separation!
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Reposted by Luis A. Ortiz-Rodríguez, PhD
Joachim Goedhart @joachimgoedhart.bsky.social · 16/11/2024
Elucidating the spatiotemporal dynamics of glucose metabolism with genetically encoded fluorescent biosensors doi.org/10.1016/j.cr...
Cartoon of biosensors for Glucose
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Reposted by Luis A. Ortiz-Rodríguez, PhD
Julie Biteen @juliebiteenlab.bsky.social · 13/11/2024
Thrilled to share Luis' manuscript showing how bacterial ribonucleoprotein bodies (BR-bodies) control RNA metabolism: stress changes the bacterial biomolecular condensate material state *and* shifts function from mRNA decay to storage. #LiveCell #SingleMolecule #Microscopy @schraderlab.bsky.social
Thrilled to share Luis's manuscript showing how RNA metabolism by bacterial ribonucleoprotein bodies (BR-bodies) is controlled: stress changes the bacterial biomolecular condensate material state *and* shifts function from mRNA decay to storage. #LiveCell #SingleMolecule #Microscopy
 
Proposed model showing how the material state of BR-bodies tunes their activity, enabling a transition from mRNA decay enhancement during growth to storage during stress.
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