Existing notions of pangenome coordinates rely on hard-to-compute multiple sequence alignments. On the other hand, pangenome-wide exact unique matches (multi-MUMs) can be computed efficiently, and represent conserved stretches of columns in the underlying MSA. We introduce Shredtools, which uses mul …

Hear from Nadia Shakoor (Donald Danforth Plant Science Center), John Lovell (HudsonAlpha Institute for Biotechnology), and Jeremy Schmutz (head of the JGI’s Plant Program, HudsonAlpha) about how a sor...

A pangenome reference for the phenotypically diverse crop sorghum aims to help accelerate future efforts to breed crops that are better adapted to changing environments.

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A national conservation group is joining their fight, saying the center will have a major impact on a fish population found only in this area of Alabama.

Summary · Eukaryotic genomes harbor many forms of variation, including nucleotide diversity and structural polymorphisms, which experience natural selection and contribute to genome evolution and biod...

Postdoctoral Research Associate - Plant Systems Biology & The Center for Bioenergy Innovation (CBI)

Motivation Pangenome graphs integrate multiple assemblies to represent non-redundant genetic diversity. However, current evaluations of pangenome graph quality rely primarily on technical parameters (...

Whole genome duplication provides evolutionary opportunities to increase biological complexity and phenotypic diversity by selective retention of duplicated genes. We identify a small genomic region a...

A local-haplotagging-based small and structural variant caller - yangao07/longcallD

The availability of genomes for many plant and animal species provides opportunities to compare genomes. These comparisons provide insights into the variability of genome structure and content within ...

If you have been keeping up with our GATK release notes, then you know that we have been rolling out a number of backend changes, tools, and features to GATK that we are hoping will improve the eff...

Position: STAFF-SCIENTIST: Evolutionary gen