According to classic population genetics theory, recombination shapes the efficacy of natural selection. However, whether variation in recombination rate itself translates into meaningful differences ...

Mutation-selection balance is the most plausible general mechanism for the maintenance of additive genetic variance (VA) for quantitative traits in natural populations. It is well established that the...

A step-by-step tutorial for creating meadow plots and candidate peak summaries from pixy output.

Scientists must push back against the threat of rising white nationalism and the dangerous and pseudoscientific ideas of eugenics.

Abstract. The impact of genome structure on adaptation is a growing focus in evolutionary biology, revealing an important role for structural variation and

VCFs are the most widely used data format for encoding genetic variation. By design, standard VCFs do not include data from sites where all individuals are homozygous for the reference allele ("invari...

Abstract. Recombination diversifies the genomes of offspring, influences the evolutionary dynamics of populations, and ensures that chromosomes segregate p

Abstract. Modifiers of recombination rates have been described but the selective pressures acting on them and their effect on adaptation to novel environme

If you have been keeping up with our GATK release notes, then you know that we have been rolling out a number of backend changes, tools, and features to GATK that we are hoping will improve the eff...