iiinova — where your digital self keeps evolving

Reposted by Atty (Ya-Ting) Chang

Danielle Grotjahn @nanigrotjahn.bsky.social · 22/12/2025

JCB’s Cover of the Year voting is open! I’ll just say… they are all gorgeous, but April has my heart 😍❄️🔬 #teamtomo @attychang.bsky.social

0187

Atty (Ya-Ting) Chang @attychang.bsky.social · 23/12/2025

It's such an honor to be featured in @jcb.org The Year in Cell Biology 2025 Collection!! 🤩 Huge thanks to my amazing PI @nanigrotjahn.bsky.social and my wonderful lab mate @nitishdua.bsky.social for bringing the hard copy of the magazine back from #cellbio1025 for me. It truly made my day! 🥰

0182

Reposted by Atty (Ya-Ting) Chang

Journal of Cell Biology @jcb.org · 05/12/2025

@attychang.bsky.social, @nanigrotjahn.bsky.social et al. show that cytoplasmic #ribosomes on #mitochondria alter the local membrane environment for protein import. rupress.org/jcb/article/... 📕 From The Year In Cell Biology: rupress.org/jcb/collecti... #CellBio2025

02310

Reposted by Atty (Ya-Ting) Chang

Danielle Grotjahn @nanigrotjahn.bsky.social · 17/11/2025

Prohibitins aren’t hanging out just anywhere in the membrane — they prefer the 💁‍♀️💎✨VIP section💅🪩🥂 Lab all-star @mmedina300kv.bsky.social maps these microdomains using cryo-ET + surface morphometrics. s/o to #teamtomo #cryoET co-authors @hamid13r.bsky.social @attychang.bsky.social @baradlab.com

05718

Reposted by Atty (Ya-Ting) Chang

Danielle Grotjahn @nanigrotjahn.bsky.social · 10/05/2025

It’s been a big week for the Grotjahn Lab—our very first graduate student, @mmedina300kv.bsky.social, successfully defended her PhD thesis! 🎉 So proud of everything she’s accomplished and grateful for the light she’s brought to our lab from day one ☀️⚡

3273

Reposted by Atty (Ya-Ting) Chang

Florent Waltz @florentwaltz.bsky.social · 06/05/2025

You want to start tomography? Solve structures inside cells? Reach Nyquist 😳 ? @phaips.vd.st and I have a website for you! tomoguide.github.io You'll find a tutorial on how to reconstruct tomograms, pick particles and do subtomogram averaging, using different software! Hope it will be useful !

3.8 angstrom resolution ribosome from 33 tomograms

312737

Reposted by Atty (Ya-Ting) Chang

Michaela Medina @mmedina300kv.bsky.social · 01/05/2025

So excited for this work to be out!! Thanks to @attychang.bsky.social, @hamid13r.bsky.social, blue sky less Daniel Fuentes, @nanigrotjahn.bsky.social and @tomo.science!!!

0133

Reposted by Atty (Ya-Ting) Chang

Danielle Grotjahn @nanigrotjahn.bsky.social · 01/05/2025

🚨New preprint!🚨 #teamtomo We expanded Surface Morphometrics to quantify membrane thickness from cryo-ET—revealing local variation across organelles. Led by the lab’s first grad student, @mmedina300kv.bsky.social (defending Monday! 🍾) w/ @attychang.bsky.social @hamid13r.bsky.social & @tomo.science

57431

Reposted by Atty (Ya-Ting) Chang

Ricardo D. Righetto @lifeonthewedge.bsky.social · 23/04/2025

We have updated our #MemBrain v2 preprint with a lot more details about the MemBrain-pick and MemBrain-stats modules, as well as some application examples! Stay tuned for the upcoming thread by lead author @lorenzlamm.bsky.social! 🧠🧵 #CryoET #TeamTomo www.biorxiv.org/content/10.1...

Figure 4. MemBrain v2 end-to-end workflow detects periodic phycobilisome organization. A: Raw tomogram slice of EMD-31244. B: Out-of-the-box MemBrain-seg segmentation (light blue). C: A single membrane instance can be visualized in Surforama and manually annotated with GT phycobilisome positions (magenta). D: MemBrain-pick localizes particles (trained with data from C) on all membranes in the tomogram. E: MemBrain-stats computes Ripley’s O statistic using the positions from D with a bin size of 5nm. The distance between peaks (35 nm) was measured to estimate chain unit spacings.

37020

Atty (Ya-Ting) Chang @attychang.bsky.social · 10/04/2025

Feeling so honored and thrilled to see our work make it to the cover—what a milestone in my career! I can’t wait to receive the poster from JCB🤩

1156

Atty (Ya-Ting) Chang @attychang.bsky.social · 09/04/2025

Happy to share the first paper in my PhD is published in JCB! It's my honor to work with amazing teammates! I really enjoy exploring mitochondrial protein import mechanism through cryo-ET!

0358

Reposted by Atty (Ya-Ting) Chang

Journal of Cell Biology @jcb.org · 13/03/2025

Cytoplasmic #ribosomes on #mitochondria alter the local membrane environment for protein import, say Ya-Ting Chang, Danielle Grotjahn (@nanigrotjahn.bsky.social) @scripps.edu and colleagues: rupress.org/jcb/article/... #ProteinHomeostasis #Organelles #StructuralBiology #CryoET

03113