Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 21/05/2026Great turnout for the career networking session this afternoon at @canacn.bsky.social ! Huge thanks to all the participants for making it great! 0102
Reposted by A.Bossonalquierthierry.bsky.social @alquierthierry.bsky.social · 14/04/20261/ Excited & proud to share the results of an exceptional collaboration with @ejrideout.bsky.social led by R. Manceau & D. Majeur @crchum.bsky.social & @umontreal-en.bsky.social, demonstrating the conserved role of lipid droplet function in hunger-activated neurons. www.nature.com/articles/s42... 11811
Reposted by A.BossonThe Transmitter @thetransmitter.bsky.social · 24/03/2026“Based on astrocytic activity alone, you can tell whether a mouse is in its comfort zone,” a new study suggests. By Holly Barker www.thetransmitter.org/spectrum/ast...thetransmitter.orgAstrocytes in mouse amygdala encode emotional stateThe glial cells’ activity reliably tracks with freezing, hesitancy and other behaviors reminiscent of anxiety. 0169
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 24/03/2026The major finding of this work reveals that BLA astrocyte calcium activity reliably encodes and drives anxiety states. This entire project started when Ossama showed me this video - 1102
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 24/03/2026Incredibly proud of this paper led by @ossamaghenissa.bsky.social and @mathiasgua.bsky.social titled Basolateral 'Amygdala Astrocytes Encode Anxiety States'. www.cell.com/neuron/fullt... 🧵 belowcell.comBasolateral amygdala astrocytes encode anxiety statesGhenissa et al. provide evidence that basolateral amygdala astrocytes reliably encode anxiety states. Using simultaneous in vivo calcium recordings across an array of behavioral tasks, combined with g... 138728
A.Bosson @astroantho.bsky.social · 06/02/2026Astrocytic opposition for this #FluorescenceFriday, Cytoskeleton vs. Cytoplasm. ⚪️GFAP 🟠eGFP 🔵DAPI Imaging credit: undergrad Camila Cabarcas 0132
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 04/02/2026Couldn't wait for Friday to share this really incredible image from superstar undergraduate student Camila Cabarcas, iInvestigating astrocyte morphology Fingers crossed for Camila as she's at U Cincinnati this week to interview for grad school! 0261
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 08/01/2026Delighted to share our first preprint of the year! A project that we're all really proud of in the lab led by @ossamaghenissa.bsky.social with @mathiasgua.bsky.social in which we set out to test the role of basolateral amygdala astrocytes in anxiety behaviour. www.biorxiv.org/content/10.6...biorxiv.orgAstrocytic Encoding of Threat in the Basolateral AmygdalaThe basolateral amygdala (BLA) has long been implicated in threat detection and the generation of anxiety states. While previous experiments have demonstrated the important role of BLA principal neuro... 45219
A.Bosson @astroantho.bsky.social · 05/12/2025Went fishing for this #FluorescenceFriday (GCaMP6s zebrafish larvae) 051
A.Bosson @astroantho.bsky.social · 04/11/2025The views we are lucky to witness from the @crchum.bsky.social 000
Reposted by A.BossonJun Nagai @junnagai.bsky.social · 15/10/2025Just out in Nature! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory nature.com/articles/s41.... New astrocyte tools are openly available at Addgene: addgene.org/Jun_Nagai/. 1/8 48327
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 05/09/2025L’impact du stress sur le cerveau dépendrait du sexe www.lapresse.ca/actualites/s...lapresse.caÉtude réalisée à Montréal | L’impact du stress sur le cerveau dépendrait du sexeLe cerveau des mâles et des femelles ne réagit pas de la même manière au stress, démontrent pour la première fois des travaux réalisés à Montréal. 251
Reposted by A.BossonMasha Prager-Khoutorsky @mashapk.bsky.social · 19/08/2025Thrilled to share our new study showing microglia prune astrocyte processes in adult brain, to regulate synaptic transmission, hypothalamic neuron activity, and salt-induced hypertension in🐀. Huge team effort - congratulations to all🥂🍾🎉 23213
Reposted by A.BossonScience News @scinews.bsky.social · 28/05/2025Sleep loss is a metabolic disorder "This review describes how sleep deprivation increases resting energy expenditure, leading to the development of a negative energy balance in highly active cells like neurons." www.science.org/doi/10.1126/...science.orgSleep loss is a metabolic disorderSleep deprivation shifts metabolic resources and deprioritizes processes that support cognition. 1235
Reposted by A.BossonCANGlia @canglia.bsky.social · 20/05/2025@lewisholt.bsky.social sharing some cool data about astrocytes driving stress-induced behaviour! #astroglia 1174
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 21/03/2025Very happy to share several common protocols used in our lab for the second edition of the book "Astrocytes: Methods and Protocols" @lewisholt.bsky.social @astroantho.bsky.social Thanks @dibenedetto-lab.bsky.social for being a very patient editor! link.springer.com/book/10.1007...link.springer.comAstrocytesThis book gathers methods essential for investigating the multifaceted roles of astrocytes in both physiology and pathological conditions. 4327
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 19/03/2025Montréal glia people / neuroscience community - I'm hosting Jun Nagai (RIKEN) on April 2nd at the @crchum.bsky.social If you're interested see details below, or reach out to me! Open to all. 0169
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 05/02/2025Not sure if our 'striking image' we submitted will get used but here it is. Super striking, if you ask me! Credit - @mathiasgua.bsky.social 061
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 01/02/2025Very honoured to be named the researcher of the month by SENSUM - the mental health and neuroscience strategy at @umontreal.ca www.sensum.umontreal.ca/en/2025/01/3...sensum.umontreal.ca🎉 Félicitations à notre chercheur du mois de février – Dr Ciaran Murphy-Royal ! 🎉Dr. Ciaran Murphy-Royal is an assistant professor in the Department of Neurosciences at the Université de Montréal and a principal investigator at the Centre de Recherche du Centre Hospitalier de l’Un... 4463
Reposted by A.BossonJustin Lines @jlines.bsky.social · 20/01/2025Astrocyte physiologists and computationalists! Imaging astrocyte structure and function, we discovered and quantified a spatial threshold to astrocyte calcium surge ⭐ doi.org/10.7554/eLif...doi.orgA spatial threshold for astrocyte calcium surgeIn astrocytes, there exists an intrinsic spatial threshold of subcellular calcium levels that triggers an astrocyte calcium surge throughout the cell, demonstrating cellular astrocyte calcium integrat... 081
A.Bosson @astroantho.bsky.social · 17/01/2025A touch of blue velvet LUT with this #FluorescenceFriday GCaMP8 astrocytic activities at the 2p 1242
Reposted by A.Bossonallen institute @alleninstitute.org · 17/12/2024How convenient - this tree already comes with ornaments! 🎄🧪 Get into the holiday spirit with this beautiful cell tree by @oozguc.bsky.social from @ibecbarcelona.eu. This beautiful fusion of science and art was made using our Lamin B1 stem cell line! What would you want to see under your cell tree? 08711
A.Bosson @astroantho.bsky.social · 20/12/20242 eGFP #astrocytes contacting a blood vessel with their arborization almost looking like a christmas tree for this #fluorescencefriday #astrocyte 0132
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 09/12/2024Delighted to share an update to our preprint, reviewed at @elife.bsky.social, and now sent back for re-review. Colossal work by the team and driven home by @mathiasgua.bsky.social Quick 🧵 of what's new - www.biorxiv.org/content/10.1...biorxiv.orgEarly-life stress induces persistent astrocyte dysfunction associated with fear generalisationEarly-life stress can have lifelong consequences, enhancing stress susceptibility and resulting in behavioural and cognitive deficits. While the effects of early-life stress on neuronal function have ... 28632
Reposted by A.BossonShane Liddelow @liddelowsa.bsky.social · 06/12/2024we haven't talked about this in the SKY> exciting preprint from Kevin Guttenplan in Marc Freeman's lab at @volluminstitute.bsky.social Adrenergic signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity www.biorxiv.org/content/10.1... 1313
Reposted by A.BossoneLife @elife.bsky.social · 26/11/202410/ Why should you bring #preprints into your journal club? Here’s what #ECRs stand to gain by looking beyond published papers. buff.ly/3VbvNjT buff.lyPoint of View: Journal clubs in the time of preprintsEarly-career researchers can learn about peer review by discussing preprints at journal clubs and sending feedback to the authors. 1157
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 03/12/2024New paper from our neighbours Stephanie Fulton’s lab investigating microglia, inflammation and synaptic transmission in the NAc. www.biorxiv.org/content/10.1...biorxiv.orgMicroglial engulfing of glutamatergic inputs and diminished excitability of D1 medium spiny neurons of the nucleus accumbens by peripheral inflammatory insultNeuroimmune responses to systemic inflammation can generate anxiodepressive behaviors and psychomotor slowing. The nucleus accumbens (NAc) is a neural hub encoding mood and motivation that contributes... 1277
Reposted by A.BossonMonica Carson @brainimmunity.bsky.social · 17/11/2024some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed? go.bsky.app/MHtJzeC 358749
Reposted by A.BossonLewis Holt @lewisholt.bsky.social · 15/11/2024Not sure I have any good pictures in the back pocket to beat the calcium imaging from @mathiasgua.bsky.social Instead for my first post on Bluesky I want to share the CANglia webinar: trainee series! 151
Reposted by A.BossonThe Transmitter @thetransmitter.bsky.social · 20/11/2024Still thinking about which neuroscience conferences to attend next year? Explore our events page, featuring a curated list of top neuroscience meetings with topic-based filters. Plus, check out upcoming webinars compiled by @worldwideneuro.bsky.social. thetransmitter.org/events 58224
Reposted by A.BossonCiaran Murphy-Royal @murphyroyallab.org · 20/11/2024Interesting to see how this is all shaping up! I’m still really proud that the first data paper from my lab went into eLife with the new model, which I think is a great system. (We’ll be updating the manuscript based on these reviews in the very near future) 0133