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A.Bosson

@astroantho.bsky.social
211 followers 379 following 13 posts

Astrocyte nerd CRCHUM - Montreal Murphy-Royal lab www.murphyroyallab.org

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Ciaran Murphy-Royal @murphyroyallab.org · 21/05/2026
Great turnout for the career networking session this afternoon at @canacn.bsky.social ! Huge thanks to all the participants for making it great!
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alquierthierry.bsky.social @alquierthierry.bsky.social · 14/04/2026
1/ Excited & proud to share the results of an exceptional collaboration with @ejrideout.bsky.social led by R. Manceau & D. Majeur @crchum.bsky.social & @umontreal-en.bsky.social, demonstrating the conserved role of lipid droplet function in hunger-activated neurons. www.nature.com/articles/s42...
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The Transmitter @thetransmitter.bsky.social · 24/03/2026
“Based on astrocytic activity alone, you can tell whether a mouse is in its comfort zone,” a new study suggests. By Holly Barker www.thetransmitter.org/spectrum/ast...
thetransmitter.org
Astrocytes in mouse amygdala encode emotional state
The glial cells’ activity reliably tracks with freezing, hesitancy and other behaviors reminiscent of anxiety.
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Ciaran Murphy-Royal @murphyroyallab.org · 24/03/2026
The major finding of this work reveals that BLA astrocyte calcium activity reliably encodes and drives anxiety states. This entire project started when Ossama showed me this video -
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Ciaran Murphy-Royal @murphyroyallab.org · 24/03/2026
Incredibly proud of this paper led by @ossamaghenissa.bsky.social and @mathiasgua.bsky.social titled Basolateral 'Amygdala Astrocytes Encode Anxiety States'. www.cell.com/neuron/fullt... 🧵 below
cell.com
Basolateral amygdala astrocytes encode anxiety states
Ghenissa et al. provide evidence that basolateral amygdala astrocytes reliably encode anxiety states. Using simultaneous in vivo calcium recordings across an array of behavioral tasks, combined with g...
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A.Bosson @astroantho.bsky.social · 06/02/2026
Astrocytic opposition for this #FluorescenceFriday, Cytoskeleton vs. Cytoplasm. ⚪️GFAP 🟠eGFP 🔵DAPI Imaging credit: undergrad Camila Cabarcas
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Ciaran Murphy-Royal @murphyroyallab.org · 04/02/2026
Couldn't wait for Friday to share this really incredible image from superstar undergraduate student Camila Cabarcas, iInvestigating astrocyte morphology Fingers crossed for Camila as she's at U Cincinnati this week to interview for grad school!
Fluorescence image showing astrocytes labelled with eGFP (green), what appears to be primary blood vessels with GFAP (magenta), and cell nuclei stained with DAPI (cyan)
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Ciaran Murphy-Royal @murphyroyallab.org · 08/01/2026
Delighted to share our first preprint of the year! A project that we're all really proud of in the lab led by @ossamaghenissa.bsky.social with @mathiasgua.bsky.social in which we set out to test the role of basolateral amygdala astrocytes in anxiety behaviour. www.biorxiv.org/content/10.6...
biorxiv.org
Astrocytic Encoding of Threat in the Basolateral Amygdala
The basolateral amygdala (BLA) has long been implicated in threat detection and the generation of anxiety states. While previous experiments have demonstrated the important role of BLA principal neuro...
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A.Bosson @astroantho.bsky.social · 05/12/2025
Went fishing for this #FluorescenceFriday (GCaMP6s zebrafish larvae)
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A.Bosson @astroantho.bsky.social · 04/11/2025
The views we are lucky to witness from the @crchum.bsky.social
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Jun Nagai @junnagai.bsky.social · 15/10/2025
Just out in Nature! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory nature.com/articles/s41.... New astrocyte tools are openly available at Addgene: addgene.org/Jun_Nagai/. 1/8
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Ciaran Murphy-Royal @murphyroyallab.org · 05/09/2025
L’impact du stress sur le cerveau dépendrait du sexe www.lapresse.ca/actualites/s...
lapresse.ca
Étude réalisée à Montréal | L’impact du stress sur le cerveau dépendrait du sexe
Le cerveau des mâles et des femelles ne réagit pas de la même manière au stress, démontrent pour la première fois des travaux réalisés à Montréal.
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Masha Prager-Khoutorsky @mashapk.bsky.social · 19/08/2025
Thrilled to share our new study showing microglia prune astrocyte processes in adult brain, to regulate synaptic transmission, hypothalamic neuron activity, and salt-induced hypertension in🐀. Huge team effort - congratulations to all🥂🍾🎉
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A.Bosson @astroantho.bsky.social · 11/07/2025
Go Lewis 👏👏👏
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Science News @scinews.bsky.social · 28/05/2025
Sleep loss is a metabolic disorder "This review describes how sleep deprivation increases resting energy expenditure, leading to the development of a negative energy balance in highly active cells like neurons." www.science.org/doi/10.1126/...
science.org
Sleep loss is a metabolic disorder
Sleep deprivation shifts metabolic resources and deprioritizes processes that support cognition.
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CANGlia @canglia.bsky.social · 20/05/2025
@lewisholt.bsky.social sharing some cool data about astrocytes driving stress-induced behaviour! #astroglia
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Ciaran Murphy-Royal @murphyroyallab.org · 21/03/2025
Very happy to share several common protocols used in our lab for the second edition of the book "Astrocytes: Methods and Protocols" @lewisholt.bsky.social @astroantho.bsky.social Thanks @dibenedetto-lab.bsky.social for being a very patient editor! link.springer.com/book/10.1007...
link.springer.com
Astrocytes
This book gathers methods essential for investigating the multifaceted roles of astrocytes in both physiology and pathological conditions.
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Ciaran Murphy-Royal @murphyroyallab.org · 19/03/2025
Montréal glia people / neuroscience community - I'm hosting Jun Nagai (RIKEN) on April 2nd at the @crchum.bsky.social If you're interested see details below, or reach out to me! Open to all.
Poster showing details for seminar from Dr Jun Nagai.

Principal Investigator 
Team Leader at RIKEN Centre for Brain Science
Tokyo, Japan



Title: Behaviorally relevant astrocyte ensembles for systems stabilization





Le conférence seront présentées en anglais

Le mercredi 2 Avril 2025 - Wednesday 2nd April 2025 at 12pm


Locale : R05.212B
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Ciaran Murphy-Royal @murphyroyallab.org · 05/02/2025
Not sure if our 'striking image' we submitted will get used but here it is. Super striking, if you ask me! Credit - @mathiasgua.bsky.social
Two-photon image showing astrocytes with stained with SR101 in magenta, membrane tethered-GCaMP in cyan
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Ciaran Murphy-Royal @murphyroyallab.org · 01/02/2025
Very honoured to be named the researcher of the month by SENSUM - the mental health and neuroscience strategy at @umontreal.ca www.sensum.umontreal.ca/en/2025/01/3...
sensum.umontreal.ca
🎉 Félicitations à notre chercheur du mois de février – Dr Ciaran Murphy-Royal ! 🎉
Dr. Ciaran Murphy-Royal is an assistant professor in the Department of Neurosciences at the Université de Montréal and a principal investigator at the Centre de Recherche du Centre Hospitalier de l’Un...
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Justin Lines @jlines.bsky.social · 20/01/2025
Astrocyte physiologists and computationalists! Imaging astrocyte structure and function, we discovered and quantified a spatial threshold to astrocyte calcium surge ⭐ doi.org/10.7554/eLif...
doi.org
A spatial threshold for astrocyte calcium surge
In astrocytes, there exists an intrinsic spatial threshold of subcellular calcium levels that triggers an astrocyte calcium surge throughout the cell, demonstrating cellular astrocyte calcium integrat...
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A.Bosson @astroantho.bsky.social · 17/01/2025
A touch of blue velvet LUT with this #FluorescenceFriday GCaMP8 astrocytic activities at the 2p
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allen institute @alleninstitute.org · 17/12/2024
How convenient - this tree already comes with ornaments! 🎄🧪 Get into the holiday spirit with this beautiful cell tree by @oozguc.bsky.social from @ibecbarcelona.eu. This beautiful fusion of science and art was made using our Lamin B1 stem cell line! What would you want to see under your cell tree?
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A.Bosson @astroantho.bsky.social · 20/12/2024
2 eGFP #astrocytes contacting a blood vessel with their arborization almost looking like a christmas tree for this #fluorescencefriday #astrocyte
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Ciaran Murphy-Royal @murphyroyallab.org · 09/12/2024
Delighted to share an update to our preprint, reviewed at @elife.bsky.social, and now sent back for re-review. Colossal work by the team and driven home by @mathiasgua.bsky.social Quick 🧵 of what's new - www.biorxiv.org/content/10.1...
biorxiv.org
Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation
Early-life stress can have lifelong consequences, enhancing stress susceptibility and resulting in behavioural and cognitive deficits. While the effects of early-life stress on neuronal function have ...
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Shane Liddelow @liddelowsa.bsky.social · 06/12/2024
we haven't talked about this in the SKY> exciting preprint from Kevin Guttenplan in Marc Freeman's lab at @volluminstitute.bsky.social Adrenergic signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity www.biorxiv.org/content/10.1...
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eLife @elife.bsky.social · 26/11/2024
10/ Why should you bring #preprints into your journal club? Here’s what #ECRs stand to gain by looking beyond published papers. buff.ly/3VbvNjT
buff.ly
Point of View: Journal clubs in the time of preprints
Early-career researchers can learn about peer review by discussing preprints at journal clubs and sending feedback to the authors.
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Ciaran Murphy-Royal @murphyroyallab.org · 03/12/2024
New paper from our neighbours Stephanie Fulton’s lab investigating microglia, inflammation and synaptic transmission in the NAc. www.biorxiv.org/content/10.1...
biorxiv.org
Microglial engulfing of glutamatergic inputs and diminished excitability of D1 medium spiny neurons of the nucleus accumbens by peripheral inflammatory insult
Neuroimmune responses to systemic inflammation can generate anxiodepressive behaviors and psychomotor slowing. The nucleus accumbens (NAc) is a neural hub encoding mood and motivation that contributes...
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Monica Carson @brainimmunity.bsky.social · 17/11/2024
some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed? go.bsky.app/MHtJzeC
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Lewis Holt @lewisholt.bsky.social · 15/11/2024
Not sure I have any good pictures in the back pocket to beat the calcium imaging from @mathiasgua.bsky.social Instead for my first post on Bluesky I want to share the CANglia webinar: trainee series!
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The Transmitter @thetransmitter.bsky.social · 20/11/2024
Still thinking about which neuroscience conferences to attend next year? Explore our events page, featuring a curated list of top neuroscience meetings with topic-based filters. Plus, check out upcoming webinars compiled by @worldwideneuro.bsky.social. thetransmitter.org/events
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Ciaran Murphy-Royal @murphyroyallab.org · 20/11/2024
Interesting to see how this is all shaping up! I’m still really proud that the first data paper from my lab went into eLife with the new model, which I think is a great system. (We’ll be updating the manuscript based on these reviews in the very near future)
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