Reposted by Apu AkkadMohanad Al-Obaidi @mycosis.bsky.social · 07/04/2025www.sciencedirect.com/science/arti... #IDSKy #MedMyco #TxIDsciencedirect.comLongitudinal Assessment of the Effect of Invasive Fungal Infections on Transplant Success in Kidney Transplant RecipientsInvasive fungal infections (IFIs) significantly impact morbidity and mortality in kidney transplant recipients (KTR), but their effect on allograft fu… 041
Apu Akkad @apuid.bsky.social · 06/04/2025And people are saying the child didn’t die of “measles.” Yet another tragedy 010
Reposted by Apu AkkadJonathan Ryder, MD @jonathanrydermd.bsky.social · 23/03/2025From @drtoddlee.bsky.social @dremilymcd.bsky.social @angelahuttner.bsky.social @josemolinagb.bsky.social et al in @jama.com Network Open: Systematic review & Non-inferiority Meta-Analysis of 7 vs 14 days for GNR BSI 4 RCTs, 7 non-inf to 14 #IDSky #ShorterIsBetter jamanetwork.com/journals/jam... 0256
Reposted by Apu AkkadOpen Forum Infectious Diseases @ofidjournal.bsky.social · 02/03/2025Prevalence of injecting-related bacterial and fungal infection among people who inject drugs: a systematic review and meta-analysis ✅ Just Accepted #IDSkybuff.lyPrevalence of injecting-related bacterial and fungal infection among people who inject drugs: a systematic review and meta-analysisDespite increasing burden of injecting-related bacterial and fungal infection, there has been no recent synthesis of their epidemiology. We performed a systematic review and meta-analysis evaluating prevalence and incidence of injecting-related infection among people who inject drugs. 253
Reposted by Apu AkkadPaul Sax @paulsaxmd.bsky.social · 27/02/2025If someone thinks the measles outbreak and childhood death in Texas are "not unusual" or "happens all the time", they are deeply misinformed. h/t @adamratnermd.bsky.social for the inspiration. blogs.jwatch.org/hiv-id-obser...blogs.jwatch.orgTragic Childhood Death from Measles Reminds Us That Some Don't Understand Either the Medical Significance or the Human HeartMy ID colleague Dr. Adam Ratner, Chief of Pediatric ID at NYU Medical Center, just published an insightful and remarkably timely book called Booster Shots: The Urgent Lessons of Measles and the Uncer... 325599
Reposted by Apu AkkadAlex Sundermann, DrPH @sundermannaj.bsky.social · 19/02/2025New pre-print from folks @ Copenhagen University Hospital: 🔬 28-month WGS surveillance 🦠 7,760 patient infections 📊 27.1% genetically related, 69% w/ epi link 💰 €1.25M net savings/year if acted upon/prevented! #IDSky more great evidence for WGS for IP&C 📄: www.medrxiv.org/content/10.1... 0178
Apu Akkad @apuid.bsky.social · 18/02/2025Nice collaborative study on valley fever prophylaxis in solid organ (non lung) transplant recipients #IDsky #TxID onlinelibrary.wiley.com/doi/10.1111/...onlinelibrary.wiley.comCoccidioidomycosis Prophylaxis in Liver, Kidney, and Heart Transplant Recipients Residing in Endemic Areas Within the United StatesOur data suggests that abdominal organ transplant recipients residing in CM-endemic areas with no prior CM exposure may not require CM prophylaxis. Therefore, we recommend implementing a shared decis... 130
Apu Akkad @apuid.bsky.social · 14/02/2025But at least none of them will have autism, isn’t that right, RFK? 011
Apu Akkad @apuid.bsky.social · 09/02/2025Very true. Cocci serologies not always reliable, especially in the immunocompromised hosts. Ag helpful, but if truly high suspicion — I’d start treatment. #TxID#IDsky 030
Apu Akkad @apuid.bsky.social · 02/02/2025Not sure why the mavs wanted to get rid of Luka so badly….there must be a lot more to this story 010
Apu Akkad @apuid.bsky.social · 01/02/2025Can anyone explain what the Trump admin is trying to accomplish by doing this?? Of course they want censorship and to “MAHA” however hiv and Sti treatments are all factual and based on significant evidence, and do not seem to be going against any pseudoscience. Purge all current information? 110
Apu Akkad @apuid.bsky.social · 01/02/2025jamanetwork.com/journals/jam... Important for physicians to not sit on the sidelines during this important time. Mass amounts of medical information and FACTs are being deleted, censored from the public and healthcare alike. This admin promised transparency but instead are getting censorship.jamanetwork.comHow Should Health Care and Public Health Respond to the New US Administration?This Viewpoint discusses scientific, medical, and public health actions, including withdrawing from the World Health Organization, taken so far during the first week of the Trump administration. 100
Apu Akkad @apuid.bsky.social · 01/02/2025Scary to see how much medical information is simply being deleted. How to keep it?? #medsky #IDsky 031
Reposted by Apu AkkadJoseph Marcus @josephmarcusid.medsky.social · 31/01/2025Post-hoc analysis of 📷 📷 study in MSSA/MRSA bacteremia: Persistent fever = indicator for complicated infection Fever on Day 4️⃣: aOR (3.7 (95% CI: 1.58-8.67)) mortality Fever on Day 7️⃣: aOR: (8.78 (95% CI: 2.78-27.7) 🚫 assn between ⬆️CRP/WBC and mortality #IDSky academic.oup.com/ofid/advance...academic.oup.comAssociation of daily body temperature, white blood cell count, and C-reactive protein with mortality and persistent bacteremia in patients with Staphylococcus aureus bacteremia: a post-hoc analysis of...AbstractIntroduction. Classification of patients with Staphylococcus aureus bacteremia (SAB) as complicated versus uncomplicated is based on a combination 23714
Apu Akkad @apuid.bsky.social · 29/01/202567 active cases of TB, likely to represent many more. Important for CDC to be on top of this, if they are allowed to.. 010
Reposted by Apu AkkadJoseph Sassine @josephsassinemd.bsky.social · 23/01/2025How to prevent infections in the increasingly immunocompromised traveler? Part 1 (non-transplant) is out now! Stay tuned for part 2! @ritawilson.bsky.social @andhen25.bsky.social @ou.edu #IDSky #TxID journals.sagepub.com/doi/10.1177/...journals.sagepub.comSage Journals: Discover world-class researchSubscription and open access journals from Sage, the world's leading independent academic publisher. 0126
Apu Akkad @apuid.bsky.social · 18/01/2025Very nice study on a very important and common issue. Does this hold true in the SOT population as well? 010
Apu Akkad @apuid.bsky.social · 18/01/2025Exciting new field. Recent review I wrote as well. Fungal diagnostics always a challenge but new promising methods starting to be utilized. #IDsky #TxIDsky www.mdpi.com/2309-608X/11...mdpi.comNew Diagnostics for Fungal Infections in Transplant Infectious Disease: A Systematic ReviewFungal infections are common in highly immunosuppressed, solid organ transplant recipients. They can be quite difficult to diagnose in a timely manner; thus, we present a review of current studies foc... 030
Apu Akkad @apuid.bsky.social · 12/01/2025This is basically better than a current patriots game for a pats fan 000
Apu Akkad @apuid.bsky.social · 12/01/2025Everyone in LA expresses their immense gratitude to @lafd.bsky.social for their tremendous courage and commitment to putting out the #LAwildfires 000
Apu Akkad @apuid.bsky.social · 09/01/2025People need to focus on helping stop this devastation rather than politicizing it. #LAfires 000
Apu Akkad @apuid.bsky.social · 09/01/2025www.mdpi.com/2309-608X/11...mdpi.comNew Diagnostics for Fungal Infections in Transplant Infectious Disease: A Systematic ReviewFungal infections are common in highly immunosuppressed, solid organ transplant recipients. They can be quite difficult to diagnose in a timely manner; thus, we present a review of current studies foc... 010
Reposted by Apu AkkadIlan Schwartz @germhuntermd.bsky.social · 01/01/2025The Emerging Threat of H5N1 to Human Health @michaelisonmd.bsky.social and @drjeannem.bsky.social in @nejm.org www.nejm.org/doi/full/10....nejm.orgThe Emerging Threat of H5N1 to Human Health | NEJMHighly pathogenic avian influenza (HPAI) A(H5N1) emerged in 1997.1 Since then, it has spread globally by migratory birds, resulting in infections in animals on every continent. HPAI A(H5N1) clade 2... 45915
Reposted by Apu AkkadIlan Schwartz @germhuntermd.bsky.social · 30/12/2024Use of voriconazole to predict susceptibility and resistance to isavuconazole for Aspergillus fumigatus using CLSI methods and interpretive criteria High rate of agreement suggests vori susceptibility can predict isa susceptibility in A fumigatus w/ CLSI AFST journals.asm.org/doi/10.1128/... 2297
Reposted by Apu AkkadIlan Schwartz @germhuntermd.bsky.social · 28/12/2024Mapping the Geographic Distribution of Dimorphic Mycoses Using a US Commercial Insurance Database @julioczuniga1.bsky.social @fungaldoc.bsky.social academic.oup.com/ofid/advance... More data to show that the geographic range of dimorphic fungal infections is much wider than taught in med school 610636
Apu Akkad @apuid.bsky.social · 24/12/2024Very nice article on difficult to treat infections, and the differences between CIED and VAD strategies 000
Reposted by Apu AkkadAntibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 25/11/2024🆕️🔥Article @thetxidjournal.bsky.social Not Just an Oxymoron: The Utilitarian's Guide to Antimicrobial Stewardship in Transplant Infectious Diseases Table ✨️2: TID ASP opportunities & initiatives #idsky #medsky #Txid onlinelibrary.wiley.com/doi/full/10.... 34720
Reposted by Apu AkkadTransplant Infectious Disease Journal @thetxidjournal.bsky.social · 03/12/2024Report from the OPTN ad hoc Disease Transmission Advisory Committee - Coccidiomycosis from Organ transplant Donors? "All 7 deceased donors had prior infection or exposure...8/20 recipients developed Cocci, resulting in a 40% transmission rate." #IDsky #TxID onlinelibrary.wiley.com/doi/10.1111/...onlinelibrary.wiley.comCoccidioidomycosis Transmission Through Solid Organ Transplantation (2013–2022): A Report of the Organ Procurement and Transplantation Network ad hoc Disease Transmission Advisory CommitteeCoccidioides infection is a rare but serious fungal disease. From 2013 to 2022, most donors with risk factors lacked serologic testing before procurement, and recipients often missed necessary prophy... 1208
Apu Akkad @apuid.bsky.social · 15/12/2024Bedaquiline great drug, but in the US not easy to get! And certainly not easy to get approved by insurance 131
Apu Akkad @apuid.bsky.social · 14/12/2024www.bridgemi.com/michigan-hea...bridgemi.comWhooping cough cases skyrocket in Michigan, as vaccinations decline | Bridge MichiganA potentially deadly disease in infants, whooping cough — pertussis — has exploded in Michigan this year, in part because of decreased vaccination rates. 010
Reposted by Apu AkkadMark Cuban @mcuban.bsky.social · 06/12/2024This is going to save hospitals a lot of money ! www.pennmedicine.org/news/news-re... 1803478506669
Apu Akkad @apuid.bsky.social · 27/11/2024Absolutely. These are high morbidity and mortality infections, especially in the hosts they typically infect. 010
Apu Akkad @apuid.bsky.social · 27/11/2024It’s important the cdc stays on top of this. So far it has been thought not much if any human transmission but seeing wastewater in urban areas needs close monitoring. 010
Apu Akkad @apuid.bsky.social · 27/11/2024Yes several extremist anti vaxxers do this and then claim To have published x amount of articles Re dangers of vaccines. Sadly, there are many people who believe them. 020
Reposted by Apu AkkadAntibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 25/11/2024Nitrofurantoin has shown exceptional durability against resistance over 70y of use 🆕️✨️What makes nitrofurantoin robust against resistance evolution,in spite of prolonged & extensive usage against UTIs? #idsky #medsky #utisky www.nature.com/articles/s44...nature.comInsights into durability against resistance from the antibiotic nitrofurantoin - npj Antimicrobials and Resistancenpj Antimicrobials and Resistance - Insights into durability against resistance from the antibiotic nitrofurantoin 0227
Apu Akkad @apuid.bsky.social · 22/11/2024I hope this potential pandemic risk is not completely ignored. 011
Apu Akkad @apuid.bsky.social · 21/11/2024Not only that but urine culture without a urinalysis. Then antibiotics to treat the positive urine culture. But no evidence of a UTI. #IDsky 062
Apu Akkad @apuid.bsky.social · 21/11/2024I think most centers have switched or are switching to prolonged infusions BLs? 011
Apu Akkad @apuid.bsky.social · 21/11/2024Promising data, olorofim could be hugely important in treating disseminated or azole “resistant” cocci. Higher importance given the rapidly increasing prevalence. 161
Apu Akkad @apuid.bsky.social · 20/11/2024Practice changing landmark study As long as you have source control, 7d abx sufficient for most bloodstream infections. Note still many exceptions exist that need further investigation. 072
Apu Akkad @apuid.bsky.social · 18/11/2024Not even a remotely credible thing to do. Look at what infections have created havoc in the last 4 years. What could happen in the next 8?? 030
Apu Akkad @apuid.bsky.social · 18/11/2024Absolutely a hugely impactful study. We now can see that shorter courses for gram neg bacteremia even in severely immunocompromised patients are the way to go — as long as there is no uncontrolled source. 021
Apu Akkad @apuid.bsky.social · 17/11/2024I don’t think removing “ toxic chemicals” would make this healthy. 000