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Apu Akkad

@apuid.bsky.social
1.8K followers 574 following 156 posts

Physician - Transplant Infectious Disease #TxID, Asst Prof of Medicine @keckmedusc | Boston sports fan | views my own #IDsky #Medsky

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Reposted by Apu Akkad
Mohanad Al-Obaidi @mycosis.bsky.social · 07/04/2025
www.sciencedirect.com/science/arti... #IDSKy #MedMyco #TxID
sciencedirect.com
Longitudinal Assessment of the Effect of Invasive Fungal Infections on Transplant Success in Kidney Transplant Recipients
Invasive fungal infections (IFIs) significantly impact morbidity and mortality in kidney transplant recipients (KTR), but their effect on allograft fu…
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Apu Akkad @apuid.bsky.social · 06/04/2025
And people are saying the child didn’t die of “measles.” Yet another tragedy
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Reposted by Apu Akkad
Jonathan Ryder, MD @jonathanrydermd.bsky.social · 23/03/2025
From @drtoddlee.bsky.social @dremilymcd.bsky.social @angelahuttner.bsky.social @josemolinagb.bsky.social et al in @jama.com Network Open: Systematic review & Non-inferiority Meta-Analysis of 7 vs 14 days for GNR BSI 4 RCTs, 7 non-inf to 14 #IDSky #ShorterIsBetter jamanetwork.com/journals/jam...
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Open Forum Infectious Diseases @ofidjournal.bsky.social · 02/03/2025
Prevalence of injecting-related bacterial and fungal infection among people who inject drugs: a systematic review and meta-analysis ✅ Just Accepted #IDSky
buff.ly
Prevalence of injecting-related bacterial and fungal infection among people who inject drugs: a systematic review and meta-analysis
Despite increasing burden of injecting-related bacterial and fungal infection, there has been no recent synthesis of their epidemiology. We performed a systematic review and meta-analysis evaluating prevalence and incidence of injecting-related infection among people who inject drugs.
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Reposted by Apu Akkad
Paul Sax @paulsaxmd.bsky.social · 27/02/2025
If someone thinks the measles outbreak and childhood death in Texas are "not unusual" or "happens all the time", they are deeply misinformed. h/t @adamratnermd.bsky.social for the inspiration. blogs.jwatch.org/hiv-id-obser...
blogs.jwatch.org
Tragic Childhood Death from Measles Reminds Us That Some Don't Understand Either the Medical Significance or the Human Heart
My ID colleague Dr. Adam Ratner, Chief of Pediatric ID at NYU Medical Center, just published an insightful and remarkably timely book called Booster Shots:  The Urgent Lessons of Measles and the Uncer...
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Apu Akkad @apuid.bsky.social · 19/02/2025
Madness for sure!
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Reposted by Apu Akkad
Alex Sundermann, DrPH @sundermannaj.bsky.social · 19/02/2025
New pre-print from folks @ Copenhagen University Hospital: 🔬 28-month WGS surveillance 🦠 7,760 patient infections 📊 27.1% genetically related, 69% w/ epi link 💰 €1.25M net savings/year if acted upon/prevented! #IDSky more great evidence for WGS for IP&C 📄: www.medrxiv.org/content/10.1...
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Apu Akkad @apuid.bsky.social · 18/02/2025
Nice collaborative study on valley fever prophylaxis in solid organ (non lung) transplant recipients #IDsky #TxID onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Coccidioidomycosis Prophylaxis in Liver, Kidney, and Heart Transplant Recipients Residing in Endemic Areas Within the United States
Our data suggests that abdominal organ transplant recipients residing in CM-endemic areas with no prior CM exposure may not require CM prophylaxis. Therefore, we recommend implementing a shared decis...
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Apu Akkad @apuid.bsky.social · 14/02/2025
But at least none of them will have autism, isn’t that right, RFK?
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Apu Akkad @apuid.bsky.social · 09/02/2025
Very true. Cocci serologies not always reliable, especially in the immunocompromised hosts. Ag helpful, but if truly high suspicion — I’d start treatment. #TxID#IDsky
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Apu Akkad @apuid.bsky.social · 02/02/2025
Not sure why the mavs wanted to get rid of Luka so badly….there must be a lot more to this story
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Apu Akkad @apuid.bsky.social · 01/02/2025
Can anyone explain what the Trump admin is trying to accomplish by doing this?? Of course they want censorship and to “MAHA” however hiv and Sti treatments are all factual and based on significant evidence, and do not seem to be going against any pseudoscience. Purge all current information?
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Apu Akkad @apuid.bsky.social · 01/02/2025
jamanetwork.com/journals/jam... Important for physicians to not sit on the sidelines during this important time. Mass amounts of medical information and FACTs are being deleted, censored from the public and healthcare alike. This admin promised transparency but instead are getting censorship.
jamanetwork.com
How Should Health Care and Public Health Respond to the New US Administration?
This Viewpoint discusses scientific, medical, and public health actions, including withdrawing from the World Health Organization, taken so far during the first week of the Trump administration.
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Apu Akkad @apuid.bsky.social · 01/02/2025
Scary to see how much medical information is simply being deleted. How to keep it?? #medsky #IDsky
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Joseph Marcus @josephmarcusid.medsky.social · 31/01/2025
Post-hoc analysis of 📷 📷 study in MSSA/MRSA bacteremia: Persistent fever = indicator for complicated infection Fever on Day 4️⃣: aOR (3.7 (95% CI: 1.58-8.67)) mortality Fever on Day 7️⃣: aOR: (8.78 (95% CI: 2.78-27.7) 🚫 assn between ⬆️CRP/WBC and mortality #IDSky academic.oup.com/ofid/advance...
academic.oup.com
Association of daily body temperature, white blood cell count, and C-reactive protein with mortality and persistent bacteremia in patients with Staphylococcus aureus bacteremia: a post-hoc analysis of...
AbstractIntroduction. Classification of patients with Staphylococcus aureus bacteremia (SAB) as complicated versus uncomplicated is based on a combination
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Apu Akkad @apuid.bsky.social · 29/01/2025
67 active cases of TB, likely to represent many more. Important for CDC to be on top of this, if they are allowed to..
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Reposted by Apu Akkad
Joseph Sassine @josephsassinemd.bsky.social · 23/01/2025
How to prevent infections in the increasingly immunocompromised traveler? Part 1 (non-transplant) is out now! Stay tuned for part 2! @ritawilson.bsky.social @andhen25.bsky.social @ou.edu #IDSky #TxID journals.sagepub.com/doi/10.1177/...
journals.sagepub.com
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
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Apu Akkad @apuid.bsky.social · 18/01/2025
Very nice study on a very important and common issue. Does this hold true in the SOT population as well?
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Apu Akkad @apuid.bsky.social · 18/01/2025
Excellent review on herpesviruses post car T.
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Apu Akkad @apuid.bsky.social · 18/01/2025
Exciting new field. Recent review I wrote as well. Fungal diagnostics always a challenge but new promising methods starting to be utilized. #IDsky #TxIDsky www.mdpi.com/2309-608X/11...
mdpi.com
New Diagnostics for Fungal Infections in Transplant Infectious Disease: A Systematic Review
Fungal infections are common in highly immunosuppressed, solid organ transplant recipients. They can be quite difficult to diagnose in a timely manner; thus, we present a review of current studies foc...
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Apu Akkad @apuid.bsky.social · 12/01/2025
This is basically better than a current patriots game for a pats fan
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Apu Akkad @apuid.bsky.social · 12/01/2025
Everyone in LA expresses their immense gratitude to @lafd.bsky.social for their tremendous courage and commitment to putting out the #LAwildfires
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Apu Akkad @apuid.bsky.social · 09/01/2025
People need to focus on helping stop this devastation rather than politicizing it. #LAfires
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Apu Akkad @apuid.bsky.social · 09/01/2025
www.mdpi.com/2309-608X/11...
mdpi.com
New Diagnostics for Fungal Infections in Transplant Infectious Disease: A Systematic Review
Fungal infections are common in highly immunosuppressed, solid organ transplant recipients. They can be quite difficult to diagnose in a timely manner; thus, we present a review of current studies foc...
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Reposted by Apu Akkad
Ilan Schwartz @germhuntermd.bsky.social · 01/01/2025
The Emerging Threat of H5N1 to Human Health @michaelisonmd.bsky.social and @drjeannem.bsky.social in @nejm.org www.nejm.org/doi/full/10....
nejm.org
The Emerging Threat of H5N1 to Human Health | NEJM
Highly pathogenic avian influenza (HPAI) A(H5N1) emerged in 1997.1 Since then, it has spread globally by migratory birds, resulting in infections in animals on every continent. HPAI A(H5N1) clade 2...
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Ilan Schwartz @germhuntermd.bsky.social · 30/12/2024
Use of voriconazole to predict susceptibility and resistance to isavuconazole for Aspergillus fumigatus using CLSI methods and interpretive criteria High rate of agreement suggests vori susceptibility can predict isa susceptibility in A fumigatus w/ CLSI AFST journals.asm.org/doi/10.1128/...
Scattergram for Aspergillus fumigatus isavuconazole MIC (mg/L) vs voriconazole MIC (mg/L) using CLSI MIC breakpoint interpretive criteria. S, susceptible; I, intermediate; R, resistant)
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Ilan Schwartz @germhuntermd.bsky.social · 28/12/2024
Mapping the Geographic Distribution of Dimorphic Mycoses Using a US Commercial Insurance Database @julioczuniga1.bsky.social @fungaldoc.bsky.social academic.oup.com/ofid/advance... More data to show that the geographic range of dimorphic fungal infections is much wider than taught in med school
Distribution of cases of blastomycosis in A) Marketscan data, B) Medicare data, and C) historical mapsDistribution of cases of hisoplasmosis in A) Marketscan data, B) Medicare data, and C) historical mapsDistribution of cases of coccidioidomycosis in A) Marketscan data, B) Medicare data, and C) historical maps
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Apu Akkad @apuid.bsky.social · 24/12/2024
Very nice article on difficult to treat infections, and the differences between CIED and VAD strategies
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Apu Akkad @apuid.bsky.social · 22/12/2024
This is not an acceptable thing to do
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Reposted by Apu Akkad
Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 25/11/2024
🆕️🔥Article @thetxidjournal.bsky.social Not Just an Oxymoron: The Utilitarian's Guide to Antimicrobial Stewardship in Transplant Infectious Diseases Table ✨️2: TID ASP opportunities & initiatives #idsky #medsky #Txid onlinelibrary.wiley.com/doi/full/10....
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Transplant Infectious Disease Journal @thetxidjournal.bsky.social · 03/12/2024
Report from the OPTN ad hoc Disease Transmission Advisory Committee - Coccidiomycosis from Organ transplant Donors? "All 7 deceased donors had prior infection or exposure...8/20 recipients developed Cocci, resulting in a 40% transmission rate." #IDsky #TxID onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Coccidioidomycosis Transmission Through Solid Organ Transplantation (2013–2022): A Report of the Organ Procurement and Transplantation Network ad hoc Disease Transmission Advisory Committee
Coccidioides infection is a rare but serious fungal disease. From 2013 to 2022, most donors with risk factors lacked serologic testing before procurement, and recipients often missed necessary prophy...
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Apu Akkad @apuid.bsky.social · 15/12/2024
Bedaquiline great drug, but in the US not easy to get! And certainly not easy to get approved by insurance
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Apu Akkad @apuid.bsky.social · 14/12/2024
www.bridgemi.com/michigan-hea...
bridgemi.com
Whooping cough cases skyrocket in Michigan, as vaccinations decline | Bridge Michigan
A potentially deadly disease in infants, whooping cough — pertussis — has exploded in Michigan this year, in part because of decreased vaccination rates.
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Apu Akkad @apuid.bsky.social · 09/12/2024
Always humbling to go back to the basics.
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Reposted by Apu Akkad
Mark Cuban @mcuban.bsky.social · 06/12/2024
This is going to save hospitals a lot of money ! www.pennmedicine.org/news/news-re...
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Apu Akkad @apuid.bsky.social · 04/12/2024
Congrats all! #medsky #IDsky
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Apu Akkad @apuid.bsky.social · 27/11/2024
Absolutely. These are high morbidity and mortality infections, especially in the hosts they typically infect.
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Apu Akkad @apuid.bsky.social · 27/11/2024
It’s important the cdc stays on top of this. So far it has been thought not much if any human transmission but seeing wastewater in urban areas needs close monitoring.
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Apu Akkad @apuid.bsky.social · 27/11/2024
Yes several extremist anti vaxxers do this and then claim To have published x amount of articles Re dangers of vaccines. Sadly, there are many people who believe them.
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Reposted by Apu Akkad
Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 25/11/2024
Nitrofurantoin has shown exceptional durability against resistance over 70y of use 🆕️✨️What makes nitrofurantoin robust against resistance evolution,in spite of prolonged & extensive usage against UTIs? #idsky #medsky #utisky www.nature.com/articles/s44...
nature.com
Insights into durability against resistance from the antibiotic nitrofurantoin - npj Antimicrobials and Resistance
npj Antimicrobials and Resistance - Insights into durability against resistance from the antibiotic nitrofurantoin
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Apu Akkad @apuid.bsky.social · 22/11/2024
I hope this potential pandemic risk is not completely ignored.
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Apu Akkad @apuid.bsky.social · 21/11/2024
Not only that but urine culture without a urinalysis. Then antibiotics to treat the positive urine culture. But no evidence of a UTI. #IDsky
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Apu Akkad @apuid.bsky.social · 21/11/2024
I think most centers have switched or are switching to prolonged infusions BLs?
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Apu Akkad @apuid.bsky.social · 21/11/2024
Promising data, olorofim could be hugely important in treating disseminated or azole “resistant” cocci. Higher importance given the rapidly increasing prevalence.
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Apu Akkad @apuid.bsky.social · 21/11/2024
Sad to see. Vaccine preventable illnesses may be next..
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Apu Akkad @apuid.bsky.social · 20/11/2024
Practice changing landmark study As long as you have source control, 7d abx sufficient for most bloodstream infections. Note still many exceptions exist that need further investigation.
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Apu Akkad @apuid.bsky.social · 19/11/2024
This has to be satire?
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Apu Akkad @apuid.bsky.social · 18/11/2024
Not even a remotely credible thing to do. Look at what infections have created havoc in the last 4 years. What could happen in the next 8??
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Apu Akkad @apuid.bsky.social · 18/11/2024
Absolutely a hugely impactful study. We now can see that shorter courses for gram neg bacteremia even in severely immunocompromised patients are the way to go — as long as there is no uncontrolled source.
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Apu Akkad @apuid.bsky.social · 17/11/2024
I don’t think removing “ toxic chemicals” would make this healthy.
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