Combined functional ultrasound imaging and Neuropixels recording of mouse brains identify two neuronal populations with opposing arousal-related activity and distinct haemodynamic response functions, that occur throughout the brain.

Anyone who has experienced an all-nighter knows that sleep regulates our emotions. As an example, mood, anxiety, and stress disorders are all associated with the dysregulation of a specific phase of sleep: rapid-eye-movement (REM) sleep. Surprisingly, most sleep researchers focus on the other and most abundant phase of sleep, non-REM (NREM) sleep. In the past years, we have discovered an extreme pattern of neural and vascular activity, affecting virtually all brain regions (with a specific pattern in the amygdala, the brain “hub” involved in emotional processing) specifically occurring during REM sleep (see image). We aim to dissect the generative mechanism of these vascular surges and interrogate their function, in relation to emotional memory and brain clearance processes. We will use a set of innovative technologies including functional ultrasound (fUS) imaging, electrophysiology, fiber photometry and optogenetics in naturally sleeping rodents, as well as advance analysis methods

Respirer, c’est automatique. Mais si le souffle permettait de comprendre le cerveau, la santé… et même d'apprécier l’art ? Dans cet épisode de Tangram, la respiration devient un terrain d’exploration ...

If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.

Artificial-intelligence systems are feeding on Wikipedia without giving back, and academic indifference is threatening the survival of what is arguably the most widely used reference work on the plane...

Even when neocortical neurons form in abnormal locations, they retain their identity and function, revealing that brain circuit formation can be guided by intrinsic developmental programs rather than ...

Nature Neuroscience - Bergel et al. show that an infraslow rhythm connecting the brain and body during sleep is shared by lizards, mammals and birds, revealing an ancestral process and reshaping...

Nature Neuroscience - Bergel et al. show that an infraslow rhythm connecting the brain and body during sleep is shared by lizards, mammals and birds, revealing an ancestral process and reshaping...