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Samuel Le Meur-Diebolt

@sdiebolt.bsky.social
85 followers 112 following 44 posts

Research Fellow in CortexLab‬ @UCL 🧑‍🔬 • Studying macroscale brain activity using fUSI in mice 🐭🧠

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Reposted by Samuel Le Meur-Diebolt
Emilie Macé @mace-lab.bsky.social · 01/10/2026
Exciting times for functional ultrasound! The field is growing fast—and we need to train the next generation. We’re launching the first Paris Ultrasound Workshop, on Dec 8–9 2026. 🎓 Leading experts 🧰 Open-source tools 👩‍🔬 For new & experienced users Register by Nov 15! Link: tinyurl.com/ParisfUSI
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Patrick Mineault @patrickmineault.bsky.social · 30/09/2026
There's a new imaging modality in town: functional ultrasound imaging. I went down a deep rabbit hole to understand how it works physically and computationally. Follow me as I show you how *you* can use it and improve it www.neuroai.science/p/functional...
neuroai.science
Functional ultrasound imaging from scratch
A new modality is coming to brain imaging
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napari @napari.org · 26/09/2026
🚀 napari is hiring Remote Developers-in-Residence! Join us to build the future of interactive n-dimensional data visualization in Python. 💻 60% Dev / 20% Maintenance / 20% Community & Outreach ⏱️ Contract, 14–35 hrs/wk 🌍 Global 100% Remote Learn more and apply today: napari.org/island-dispa...
napari.org
We’re hiring Developers-in-Residence! — napari blog documentation
Organization: napari (a NumFOCUS Sponsored Project) Position Type: Independent contractor agreement. Global, 100% Remote. Duration: One year, possibility to extend. Commitment: 0.4 to 1.0 FTE…
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The Royal Society @royalsociety.org · 29/08/2026
The Ferrier Medal and Lecture 2027 is awarded to Professor Kenneth Daniel Harris for his contributions to neuroscience by unifying experimental neurophysiology with advanced analytical methods and for pioneering methods that allow recording from thousands of neurons. #RSMedals bit.ly/4qCJZRo
A man in a black shirt smiles at the camera in front of a whiteboard covered in scientific notation.
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Matteo Carandini @carandinilab.net · 17/08/2026
I am proud of this paper. Since it came out in 2022 it has received 0 citations (yes that's a zero). But multiple young scientists have found it useful! (from other labs, so they were not coerced...). Perhaps you will find it useful too? SOME TIPS FOR WRITING SCIENCE doi.org/10.1523/ENEU...
doi.org
Some Tips for Writing Science
When preparing a scientific paper, we typically write with coauthors who have different backgrounds and styles, and we target readers who have little time and patience. To help both readers and writer...
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SWC/GCNU Neuroinformatics Unit @neuroinformatics.dev · 17/08/2026
The Neuroinformatics Unit Open Software Summer School starts today! Week one starts with: - Animals in Motion, how to use open source tools to quantify animal behaviour - Large Array Data, working with very large scientific datasets neuroinformatics.dev/open-softwar... #NIU_OSSS_26
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Anyi Liu @anyiliu.bsky.social · 29/07/2026
Pyramidal cells in the cortex send a long apical dendrite to layer 1. What is its role? What happens when it's gone? ✂️ A causal spatial role for apical dendrites in the cortex Out today with @kenneth-harris.bsky.social, @carandinilab.net and @fedrossi.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
A causal spatial role for apical dendrites in the cortex
Cortical pyramidal neurons project a long apical dendrite to layer 1 (L1), to receive synaptic inputs that are thought to provide contextual and possibly suppressive modulation. In visual cortex, thes...
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 30/07/2026
Hello, #fUSI users! We’re running a poll to rename the structural ultrasound imaging datatype in the fUSI-BIDS specification so it better reflects uses beyond angiography (e.g., including B-mode imaging). Join the fUSI Discord and share your opinion: discord.gg/5HFTcukKFt
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 20/07/2026
Hi co-activation patterns people! I've been playing around with CAPs recently and wanted to sanity-check something. My understanding is that CAP vs. anti-CAP is usually interpreted not as "activation vs. no activation", but as two opposing configurations (two poles of the same fluctuation).
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 17/07/2026
napari is such an incredible piece of scientific software! 🚀 And it's not just for visualizing static data. I've been using it for the past 6 months to drive a @verasonicsinc.bsky.social ultrasound system for #fUSI, and get a nice GUI for sequence control and live visualization! 🤩
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napari @napari.org · 12/07/2026
Struggling for something to do in a TWO DAY gap without ⚽? How about trying our pre-release of napari 0.8.0? napari.org/dev/release/... Of note, this release drops Py3.10 support and deprecates PyQt5 in favor of PyQt6. It also adds some neat new features and improvements! See below: 👇
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 09/07/2026
Remember folks: you can ship some of the most advanced LLMs on Earth, but choosing distinguishable colors for a plot remains an open research problem. openai.com/index/previe...
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Matteo Carandini @carandinilab.net · 10/06/2026
Losing one side of Superior Colliculus is bad, but losing both sides seems fine. Wait, what? Flora & team discovered why: both sides press for contra actions and against inaction, obeying an incredibly simple additive rule. Out today in bioRxiv: www.biorxiv.org/cgi/content/...
A diagram showing a sequence of linear operations, with visual signals from visual cortex added to auditory signals from auditory cortex. Prefrontal cortex sums these signals and superior colliculus provides a constant, stimulus-independent factor pushing for each eligible action. The final decision is taken via softmax.
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 07/06/2026
Interesting article on something I think is very relevant to open science: several teams analyzed the same ephys dataset and got quite different answers. Not because the analyses were bad, but because this kind of work involves many analysis choices, and those choices can change the result.
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Antoine Bergel @antbergel.bsky.social · 24/04/2026
⚠️ One week left to apply to our postdoc opening at the Paris Brain Institute ! If you have a background in neuroscience 🧠 , looking for a vibrant interdisciplinary environment in the heart of Paris, come join us !! All details below ⬇️ ⬇️.
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Agnès Landemard @agnesland.bsky.social · 15/04/2026
How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states! Out today in Nature: rdcu.be/fdC2A @uclbrainscience.bsky.social
The supply of blood to brain tissue is thought to depend on the overall neural activity in that tissue, and this dependence is thought to differ across brain regions and across brain states. However, studies supporting these views have measured neural activity as a bulk quantity and related it to blood supply following disparate events in different regions. Here we measure fluctuations in neuronal activity and blood volume across the mouse brain, and find that their relationship is consistent across brain states and brain regions but differs in two opposing brainwide neural populations. Functional ultrasound imaging (fUSI) revealed that whisking, a marker of arousal, is associated with brainwide fluctuations in blood volume. Simultaneous fUSI and Neuropixels recordings showed that neurons that increase activity with whisking have distinct haemodynamic response functions compared with those that decrease activity. Their summed contributions predicted blood volume across states.Brainwide Neuropixels recordings revealed that these opposing populations coexist in the entire brain. Their differing contributions to blood volume largely explain the apparent differences in blood volume fluctuations across regions. The mouse brain thus contains two neural populations with opposite relations to brain state and distinct relationships to blood supply, which together account for brainwide fluctuations in blood volume.
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Julie Fabre @juliefabre.bsky.social · 12/04/2026
Want to explore connectivity & projection patterns yourself, like we do here? We released brain_street_view to let you pick any injection site in the Allen Connectivity Atlas and visualize where it projects in your favorite region of interest: github.com/Julie-Fabre/brain_street_view
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Reposted by Samuel Le Meur-Diebolt
Emilie Macé @mace-lab.bsky.social · 16/03/2026
1/8. New preprint! Using fUSi in head-fixed mice🐭, we found that arousal events trigger a brain-wide wave of activity 🌊🧠. Surprisingly, this pattern was preserved during opto manipulations of the locus coeruleus, pointing to a minor role for noradrenergic tone. www.biorxiv.org/content/10.6...
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 10/04/2026
New paper out 🎉 Awake fUSI is powerful, but motion can strongly bias the data, even in head-fixed experiments. In this paper, we tried to systematically characterize those artifacts, benchmark denoising strategies, and turn that into practical recommendations for awake fUSI of mouse brains. 1/12
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Antoine Bergel @antbergel.bsky.social · 10/04/2026
⚠️ Postdoc Opportunity in System Neuroscience at the Paris Brain Institute ⚠️ Feel passionate about neuroscience and sleep 🧠? Want to learn cutting-edge techniques 🔬 to answer exciting basic science questions? Want to work in a multidisciplinary environment at the heart of Paris 🏨? Come join us !
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SWC/GCNU Neuroinformatics Unit @neuroinformatics.dev · 13/03/2026
We have three neuroscience research software engineering jobs available at @sainsburywellcome.bsky.social, two joint with the Advanced Microscopy Facility. All positions start ASAP, funded until Sept 2028 in the first instance. Salary £54-64k. More details: neuroinformatics.dev/get-involved
neuroinformatics.dev
Get involved — NIU
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 26/02/2026
Next #fUSI - #BIDS meeting is coming up! 🧠 📅 March 19, 5PM CET 🎯 Solving remaining spec remarks & moving toward official maintenance. Newcomers welcome! 🚀 Planning to BIDSify your data? Join us, we’re here to answer your questions. Details on the GDoc: docs.google.com/document/d/1...
docs.google.com
fUSI-BIDS extension proposal v0.0.12
BIDS Extension Proposal 40 (BEP040): fUSI-BIDS version 0.0.12.dev Available under the CC-BY 4.0 International license. Extension moderators/leads: Jean-Charles Mariani <jean-charles.mariani@cri-paris...
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Institute Physics for Medicine Paris @physmedparis.bsky.social · 13/01/2026
𝗞𝗶𝗰𝗸𝗶𝗻𝗴 𝗼𝗳𝗳 𝟮𝟬𝟮𝟲 𝘄𝗶𝘁𝗵 𝗮 𝗻𝗲𝘄 𝗽𝘂𝗯𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗶𝗻 𝗖𝗲𝗹𝗹 𝗥𝗲𝗽𝗼𝗿𝘁𝘀 @felipecybis.bsky.social, postdoct in our lab, is the first author of the study "A vascular code for speed in the spatial navigation system", now published in Cell Reports: doi.org/10.1016/j.celrep.2025.116791 #Ultrasound #fUS #Research
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 13/11/2025
Long-awaited #fUSI - #BIDS meeting scheduled! 🧠 📅 Nov 27, 5PM Paris time 🎯 Finalizing BEP for BIDS maintainer discussions Implemented fUSI-BIDS or planning to? We need your input to strengthen the spec. Join us! Details on the specification GDoc (docs.google.com/document/d/1...)
docs.google.com
fUSI-BIDS extension proposal v0.0.11
BIDS Extension Proposal 40 (BEP040): fUSI-BIDS version 0.0.11 Available under the CC-BY 4.0 International license. Extension moderators/leads: Jean-Charles Mariani <jean-charles.mariani@cri-paris.org...
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Emilie Macé @mace-lab.bsky.social · 11/09/2025
Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/
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ESPCI Paris - PSL @espciparispsl.bsky.social · 09/09/2025
Nicolas Zucker, PhD student at @physmedparis.bsky.social was featured last Friday on "Les chantiers de la recherche" @radiofrance.fr, where he presented his work on functional ultrasound microscopy (fULM). 🎙️🧠 Podcast available here 👉 www.radiofrance.fr/francecultur...
radiofrance.fr
Parkinson, Alzheimer : l’imagerie médicale peut-elle nous aider à lutter contre les maladies cérébrales ?
Les progrès dans le domaine de l'imagerie médicale sont essentiels pour la médecine : en concevant des technologies de pointe pour mieux documenter le fonctionnement du cerveau, les scientifiques ouvr...
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Reposted by Samuel Le Meur-Diebolt
Alessandro Gozzi @gozziale.bsky.social · 03/09/2025
This looks pretty cool: ultrasound can now see through the skull! 🧠🔊 The skull has long been a barrier to ultrasound. This reprint shows how to make it quickly transparent → enabling full-depth, high-res fUSI in mice (& humans! 🤯🤯) Huge congrats to the authors!!! www.biorxiv.org/content/10.1...
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SWC/GCNU Neuroinformatics Unit @neuroinformatics.dev · 11/08/2025
Today is the first day of the Neuroinformatics Unit Open Software Week, bringing together researchers from around the world for a week of training and collaborating on open source neuroscience software. First day is a Python programming workshop. neuroinformatics.dev/open-softwar... #niu_osw
Open software week attendees in the lecture theatre at the Sainsbury Wellcome Centre, at an "Introduction to Python" workshop
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 11/08/2025
ty is incredible for diagnostics AND as a language server! Orders of magnitude faster than Pyright and will eventually replace it. Still need Pyright for on-hover info for now, but we're moving toward a complete Astral-backed Python environment! ⚡
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Damien Fair @drdamienfair.bsky.social · 10/08/2025
I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf...
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 03/08/2025
A must read for anyone interested in studying spatial navigation with #fUSI! 🧠🗺️ @felipecybis.bsky.social really opened up new possibilities with this one!👇
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Department of Imaging Neuroscience @imagingneuroucl.bsky.social · 23/06/2025
Drumroll... The SPM team will announce that SPM is now fully accessible from Python! 🐍 Learn more about SPM-Python at the SPM roundtable event (Friday, 1pm) and poster number 1841 at #OHBM2025. Try the beta for yourself at github.com/spm/spm-python [2/7]
github.com
GitHub - spm/spm-python: The Python interface to SPM
The Python interface to SPM. Contribute to spm/spm-python development by creating an account on GitHub.
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Imaging Neuroscience @imagingneurosci.bsky.social · 21/06/2025
New paper in Imaging Neuroscience by Théo Lambert, Alan Urban, et al: Functional ultrasound imaging and neuronal activity: How accurate is the spatiotemporal match? doi.org/10.1162/IMAG...
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 21/06/2025
🧠✨ Amazing #fUSbrainDAYS2025 conference! Thanks to the organizers for bringing together the fUSI community. Poll results (53 participants): 🏝️ Corsica vs Paris: 41 vs 11 🔬 fUSi vs fUS: 33 vs 14 Looks like we're heading to Corsica next year, and embracing #fUSI!
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Bratislav Misic @misicbata.bsky.social · 20/06/2025
Benchmarking methods for mapping functional connectivity in the brain | doi.org/10.1038/s415... What is the best measure of functional connectivity (FC)? led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 18/06/2025
🚨 New preprint alert! We benchmarked 792 denoising pipelines for #fUSI in awake mice 🐭🧠 Our results show how they reduce motion artifacts and impact seed-based connectivity analyses. Check it out on @biorxivpreprint.bsky.social 👇 🔗 www.biorxiv.org/content/10.1...
biorxiv.org
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Mickael Pereira @mickaelpereira.bsky.social · 13/06/2025
🧠 Excited to share our new paper just published in eBioMedicine We report ~0.1 Hz hemodynamic waves after local neuroinflammation using functional ultrasound imaging — their presence and amplification partly driven by glial cells 📄 thelancet.com/journals/ebiom… #neuroinflammation #fUS #glia
thelancet.com
Lancet
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Nature Methods @natmethods.nature.com · 06/06/2025
An Analysis of 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure-function coupling and behavior prediction highlights their effectiveness for neurophysiological applications. www.nature.com/articles/s41...
nature.com
Benchmarking methods for mapping functional connectivity in the brain - Nature Methods
In this Analysis, Liu et al. benchmark more than 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure–function coupling and behavio...
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Amy Kuceyeski @amykooz.bsky.social · 05/06/2025
So glad to see this released!
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Alessandro Gozzi @gozziale.bsky.social · 06/05/2025
🎓 My lab has 2 PhD positions with @cimecunitrento.bsky.social 1️⃣ 🧠 Watch the 🐭 brain in motion, with functional ultrasound imaging (fUSI) 2️⃣🧪 Mess with the 🐭 brain (experimentally) via causal perturbations + imaging 🔬 Neuro/physics/bioengeneering backgrounds welcome 👉Info ▶️https://lnkd.in/dDeTTDj2
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Annie G. Bryant @anniegbryant.bsky.social · 04/05/2025
🎨🧑‍🎨 Looking for a tool to visualize subcortical/thalamic data in 2D? Check out this python-based package I put together (subcortex-visualization on PyPI), plus a guide for creating your own custom atlas meshes and vector graphics! All feedback/tips welcome 😊 anniegbryant.github.io/subcortex_vi...
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The Transmitter @thetransmitter.bsky.social · 29/04/2025
Systems neuroscientists could use a tool that allows them to tweak neuronal activity and record at the same time. The Neuropixels Opto probe, although still a protoype, might be such a device. By @claudia-lopez.bsky.social #neuroskyence www.thetransmitter.org/neuropixels/...
thetransmitter.org
‘Perturb and record’ optogenetics probe aims precision spotlight at brain structures
The tool provides a new way to characterize cells and study neuronal circuits.
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Christophe 🔬 Leterrier @christlet.bsky.social · 26/04/2025
"Choose France for Science!" *government cuts half a billion more to the research budget*
lemonde.fr
Le gouvernement annule 3,1 milliards d’euros de crédit pour les missions écologie, économie et recherche et enseignement supérieur
Selon un décret publié samedi au « Journal officiel », ces annulations sont faites dans le cadre de l’effort supplémentaire de 5 milliards d’euros pour 2025.
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Andrea Brovelli @brovelli.bsky.social · 25/04/2025
New Call for International Researchers interested in working in France. From postdoc to senior PIs. carrieres.cnrs.fr/actualites/i...
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 22/04/2025
🚨 Next #fUSI-BIDS meeting 🚨 Hey fUSI users! The next fUSI-BIDS meeting will take place tomorrow 23/04 at 5:00pm CEST. Please join us and participate in drafting this new standard! Details and meeting link are in the specification GDoc (docs.google.com/document/d/1...). See you soon! 🧠
docs.google.com
fUSI-BIDS extension proposal v0.0.11
BIDS Extension Proposal 40 (BEP040): fUSI-BIDS version 0.0.11 Available under the CC-BY 4.0 International license. Extension moderators/leads: Jean-Charles Mariani <jean-charles.mariani@cri-paris.org>...
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The Transmitter @thetransmitter.bsky.social · 18/04/2025
Neuroscientists should embrace variability in neuroimaging studies, according to researchers who showed that decision-making is associated with subtypes of brain activity. By @claudia-lopez.bsky.social #neuroskyence www.thetransmitter.org/behavior/dur...
thetransmitter.org
During decision-making, brain shows multiple distinct subtypes of activity
Person-to-person variability in brain activity might represent meaningful differences in cognitive processes, rather than random noise.
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Thomas Yeo @bttyeo.bsky.social · 26/03/2025
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
nature.com
A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications
Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.
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Marc L Seal @parkvillegeek.bsky.social · 24/03/2025
The impact of heterogeneous spatial autocorrelation on comparisons of brain maps | bioRxiv www.biorxiv.org/content/10.1...
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Alessandro Gozzi @gozziale.bsky.social · 06/03/2025
Can we use brain scans to identify biologically distinct "autisms"? And If so, how? In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions! Find out more here 👇👇 www.biorxiv.org/content/10.1... Thread below 🧵 1/n
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Samuel Le Meur-Diebolt @sdiebolt.bsky.social · 06/03/2025
Great article by @thetransmitter.bsky.social on making #neuroimaging tools accessible! As someone working in #fUSI, I strongly believe dedicated #OpenScience solutions are essential for our field to advance. Hope to contribute to these efforts in the future.​​​​​​​​​​​​​​​​
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