iiinova — where your digital self keeps evolving

Reposted by Andrew Plygawko

Zebrafish Rock! 🎃 @zebrafishrock.bsky.social · 22/08/2026

Find out how RNA control your immune system! The Renshaw Lab (Sheffield) are hiring TWO PDRAs to study RNA-binding protein ELAVL1 in neutrophils using human cells, #zebrafish, multi-omics. Closes 26/8 Wet lab-based: www.jobs.ac.uk/job/DSK873/r... Bioinformatics-based: www.jobs.ac.uk/job/DSK931/r...

Neutrophil migration over time during inflammation. Credit to Catherine Loynes.

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David Green @greenbaron.bsky.social · 13/08/2026

Really excited to finally show off our work on the specification of neuroblasts. While it has been a long-standing model for lateral inhibition, we show that Notch does not select the NB, but instead reinforces fate decisions. www.cell.com/current-biol... @currentbiology.bsky.social

cell.com

Positional cues, not Notch, direct neuroblast selection during early neurogenesis in the Drosophila embryo

Using quantitative live imaging, Green et al. show that proneural gene expression is biased by positional cues and that Notch is activated only after neuroblast selection in the Drosophila embryo. Thi...

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Reposted by Andrew Plygawko

European Drosophila Society @fly-eds.bsky.social · 13/07/2026

📣 📣 📣 📣 To all Drosophilists: the call for Workshop proposals at the 2027 European Drosophila Research Conference in Bonn (20-23 September 2027) is OPEN! Go to link below for instructions. Closing date: 30 September 2026. 👇🏻👇🏻👇🏻 tinyurl.com/45y8trzd

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Rory Cooper @rorylcooper.bsky.social · 02/07/2026

Check out this new work from the Towers lab to learn how avian digit patterns can be transformed into mammalian-like patterns! 🔬🐣🧪 @matt-towers.bsky.social Video: www.youtube.com/watch?v=fvL_... Preprint: www.biorxiv.org/content/10.6...

youtube.com

Transforming Avian to Mammalian Modes of Digit Patterning

YouTube video by Matteo de la Torre

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Stefan Luschnig @luschnig.bsky.social · 18/04/2025

Check out new work @plosbiology.org from Daniel St Johnston´s lab visualizing how secretory cargo is targeted to apical vs. basolateral domains in #epithelial cells in real time. Nice collaboration highlighting the power of #RUSH in #Drosophila!

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Young Embryologist Network @yen-network.bsky.social · 06/04/2025

🚨 Abstracts are due next week! 🚨 Submit your abstract to give a talk or poster at YEN 2025 by the 12th April! Share this opportunity with dev bio and stem cell PhD students. The conference is FREE and full of great science. We are looking forward to seeing you there!

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Irene Miguel-Aliaga @irenemiguel-aliaga.bsky.social · 19/03/2025

Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...

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Katja Rust @rustflylab.bsky.social · 07/03/2025

I am thrilled to announce our latest #SingleCell manuscript: www.biorxiv.org/content/10.1... We show that overactivation of Hh #signaling induces an EMT-like hybrid state in #Drosophila follicle cells. However, when we simultaneously overactivate EGFR/RAS signaling the cells form a lethal #cancer!

biorxiv.org

Independent signaling pathways provide a fail-safe mechanism to prevent tumorigenesis

Controlled signaling activity is vital for normal tissue homeostasis and oncogenic signaling activation facilitates tumorigenesis. Here we use single-cell transcriptomics to investigate the effects of...

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Frank Schnorrer @frankschnorrer.bsky.social · 06/03/2025

Spatial transcriptomics in fly brain and body. Wonderful collaboration with @steinaerts.bsky.social led by @jasperjanssens.bsky.social @pierremangeol.bsky.social Nikolai Hecker & Gabriele Partel - look at mRNA patterns in muscles and brains spatialfly.aertslab.org elifesciences.org/reviewed-pre...

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Kyra Campbell @kyracampbelllab.bsky.social · 27/02/2025

Excited to welcome all our Dev Bio friends (and maybe even some Cell Biologists) to Sheffield for the Northern(ish) England Developmental Biology meeting 10th July. We have some great speakers from the places in England where you get called Duck or Love and plenty of slots for ECR talks.

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Rory Cooper @rorylcooper.bsky.social · 27/02/2025

The Northern England Developmental Biology @bsdb.bsky.social @biologists.bsky.social meeting takes place on July 10th in Sheffield. Register by May 31st - its gonna be cool 😎 (see the poster below for details)!

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Anestis Tsakiridis @tsakiridis.bsky.social · 20/02/2025

Development folks: the next Northern England Developmental Biology @bsdb.bsky.social @biologists.bsky.social meeting will take place on the 10th of July in Sheffield. Great speaker line-up, cheap registration fee and plenty of slots for ECR talks. Registration deadline=31/5, see poster for details

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Constantin Pape @cppape.bsky.social · 12/02/2025

After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool. www.nature.com/articles/s41...

Improvements in LM (top) and EM (bottom) of our micro-sam model (finetuned) compared to the default SAM model.

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David Strutt @struttlab.bsky.social · 08/02/2025

New! 15y after the classic Aigouy et al "Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium..." from lab of much missed Suzanne Eaton, we provide our take from post-doc Sara Tan "Tissue shear as a cue for aligning planar polarity in the developing Drosophila wing". rdcu.be/d81Vn

Planar polarity in the Drosophila pupal wing is oriented by tissue stress but the mechanisms remain unclear. This study uncovers a crucial role for cell flow gradients in promoting planar polarity protein turnover and aligning proximodistal polarity.

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Young Embryologist Network @yen-network.bsky.social · 30/01/2025

Registration and abstract submission for YEN 2025 is officially open! We are looking forward to seeing you at the 17th Young Embryologist Network Conference on the 19th May 2025. Attendence is FREE thanks to our amazing sponsors: @biologists.bsky.social @10xgenomics.bsky.social and Azenta.

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corderolab.bsky.social @corderolab.bsky.social · 23/01/2025

Research Assistant/Associate Position in the lab. Fully funded until February 2028. Please apply if you are passionate about inter-organ signalling and intestinal biology...And off course, our wonderful Drosophila! Position details and application link below www.jobs.gla.ac.uk/job/research...

jobs.gla.ac.uk

Research Assistant/Associate - Intestinal biology and interorgan signaling

Job Purpose We have a fully funded Research Assistant/Associate position available in the laboratory of Professor Julia Cordero. You will contribute to a project studying interorgan signaling coo...

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Jo Sharpe @comeflywithjo.bsky.social · 06/01/2025

Top Trumps - but make it science 🤓 I had the most fun designing these, and I've written about how you could use it in your outreach programme! I'm keen to spread the word to any educators/academics who might be interested - please share 🤗 @nc3rs.bsky.social thenode.biologists.com/biological-r...

thenode.biologists.com

Biological Research Trump Cards: from fruit flies to stem cells... who will come out on top? - the Node

In 2023 I was awarded a NC3Rs 20th Anniversary Public Engagement Award to develop and print a "Biological Research Trump Cards" game. I have now designed

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Reposted by Andrew Plygawko

Alejandro Montenegro @aemonten.bsky.social · 12/12/2024

"We report that numerous “miRNAs” previously reported in EMT and cancer contexts are not incorporated into RISC and are not capable of endogenously silencing target genes, despite the fact that hundreds of publications in the cancer field describe their roles" www.biorxiv.org/content/10.1...

biorxiv.org

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