iiinova — where your digital self keeps evolving

Alissa Rothchild @alissarothchild.bsky.social · 16/07/2026

@jasonyanglab.org, Congratulations to you, Shuyi, and Christoph! What a fantastic team!

Reposted by Alissa Rothchild

Stand Up for Science! @standupforscience.net · 31/05/2026

What does the new OMB proposal mean for science? How can we STOP VOUGHT and SAVE SCIENCE together? All of these questions and more to be discussed at the Emergency Science Meeting on June 2nd, 4PM ET, hosted by Stand Up for Science! Register at the link in our bio, or go here: zurl.co/g3vTZ

The graphic contains photos of speakers Prof. Timothy Snyder, U. of Toronto, Author of On Tyranny, Dr. Carolyn Bertozzi, Standford U. Nobel Laureate 2022, Amb. Norman Eisen, Democracy Defeders, and Dr. Elizabeth Ginexi, 20 yr NIH Veteren, "AND MORE..." to speak. The graphic reads: "TUESDAY JUNE 2nd 4PM ET/1PM PT, All welcome for the SUFS EMERGENCY SCIENCE MEETING, VIRTUAL AND ACCESSIBLE, What does the new OMB proposal mean for science? How can we STOP VOUGHT and SAVE SCIENCE together? REGISTER HERE: https://zurl.co/oCIDw, LINK IN BIO".

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Peter Chien @chienlab.bsky.social · 19/05/2026

We are hiring! Focus is on colleagues interested in protein homeostasis and human disease. Priority reviewing starts mid-June and will continue on a rolling basis. Here is the ad, hit me up if you have questions! careers.umass.edu/jobs/assista...

careers.umass.edu

Assistant Professor of Biochemistry - Protein Homeostasis - Amherst, Massachusetts, United States

Title: Assistant Professor of Biochemistry - Protein Homeostasis Executive Area: Academic Affairs College/School/MBU: College of Natural Sciences Department: Biochemistry/Molecular Biology Work Locati...

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Jeremy Berg @jeremymberg.bsky.social · 11/05/2026

Open letter calling for the reinstatement of the National Science Board. This letter is from leaders of the National Academies Note: This does not refer to the leaders on paper such as presidents of the NAS, NAM, and NAE. www.standupforscience.net/nasem-letter... @standupforscience.net

standupforscience.net

NASEM Open Letter to Congress demanding the restoration of the NSB — STAND UP FOR SCIENCE

Support NASEM's open letter to Congress by signing your endorsement now!

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Jeremy Berg @jeremymberg.bsky.social · 13/03/2026

Following @joshuasweitz.bsky.social post and discussions with him and the Vox story, I have estimated R01 success rates for each NIH institute and center with enough awards for this to be meaningful. A long 🧵... 1/25

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Alissa Rothchild @alissarothchild.bsky.social · 12/03/2026

👏 🎉 Congratulations to Dr. Pamelia Lim (@pamelialim.bsky.social) on her outstanding thesis defense yesterday! Couldn't be more proud as a PI to have our first PhD student in the lab pass this milestone! What a bright future ahead for Dr. Lim! ✨

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Daniel L. Barber, PhD @danbarberphd.bsky.social · 05/12/2025

What we’ve got here is failure to communicate - some macrophages you just can’t reach! Multiple features of granulomas limit effective T cell:MΦ interactions, posing a major barrier for vaccine-mediated protection. Check out our new review! onlinelibrary.wiley.com/doi/10.1111/...

onlinelibrary.wiley.com

<em>Journal of Internal Medicine</em> | Wiley Online Library

Tuberculosis (TB) remains a leading infectious cause of morbidity and mortality, and the development of a new, highly effective vaccine would have a tremendous beneficial impact on global health. Alt....

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Joanne Flynn @joanneflynn19.bsky.social · 04/12/2025

Hey friends. I’m looking for a postdoc interested in studying host-pathogen interactions and immunology of tuberculosis. Send me some good people! We have a great group here! Email me joanne@pitt.edu. Thanks!

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Alissa Rothchild @alissarothchild.bsky.social · 20/11/2025

Don't wait to apply! The deadline is coming up soon... Come join us! Western Mass is a fantastic place to do science!

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Alissa Rothchild @alissarothchild.bsky.social · 12/11/2025

Our findings reveal both shared and distinct Mtb responses of AM and MDM across species and highlight the need to use both animal models and human studies in tandem to dissect mechanisms of disease. Big thank you to everyone who contributed to the project! (5/5)

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Alissa Rothchild @alissarothchild.bsky.social · 12/11/2025

Lastly, examination of candidate genes revealed that low #MAF and #IL10 expression were two features that distinguished AM from MDM across species, suggesting regulation of cell proliferation and immunosuppression differs across macrophage subsets. (4/5)

Gene boxplot for MAF and IL10 expression

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Alissa Rothchild @alissarothchild.bsky.social · 12/11/2025

Second, we found that responses from murine AM isolated from #BCG vaccinated or coMtb-infected mice were more similar to responses of human AM than those from naive mice, suggesting that prior systemic exposure is critical for shaping the human airway immune response. (3/5)

Pathway analysis summary of human and murine AM responses to Mtb

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Alissa Rothchild @alissarothchild.bsky.social · 12/11/2025

This team effort revealed several interesting findings... First, we found that while all #macrophages generated strong #interferon responses to Mtb in vitro, AM from both species showed weaker inflammatory responses to Mtb than human MDM or murine BMDM, despite higher baseline levels. (2/5)

Dot plot of pathway analysis for MDM vs AM responses

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Journal of Experimental Medicine @jem.org · 04/11/2025

First impressions count in #TB. Andrea Cooper @uniofleicester.bsky.social discusses studies by @wjbranchett.bsky.social et al. (rupress.org/jem/article/...) and @bengern.bsky.social et al. (rupress.org/jem/article/...), in Insights: rupress.org/jem/article/...

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Elizabeth Warren @warren.senate.gov · 18/10/2025

Donald Trump is weak. He’s a bully. And when we won’t bow down to kings or to bullies, they start to lose their power. The American people do not bow down.

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Indivisible ❌👑 @indivisible.org · 18/10/2025

😍 Boston, you are beautiful. #NoKings

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Alissa Rothchild @alissarothchild.bsky.social · 15/10/2025

🚨Job posting! #UMassAmherst Department of Veterinary and Animal Sciences is hiring a TT faculty member in #Immunology. Both fundamental and translational areas considered. Please spread the word! careers.umass.edu/amherst/en-u...

careers.umass.edu

Details - Assistant Professor - Immunology | Human Resources | UMass Amherst

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Kristen DeAngelis 🏳️‍🌈🏳️‍⚧️🍉 @kristenobacter.bsky.social · 02/10/2025

UMass Amherst Microbiology is hiring a tenure-track virologist. Come work with me! 🦠🧪 careers.umass.edu/amherst/en-u...

careers.umass.edu

Details - Assistant Professor - Virology | Human Resources | UMass Amherst

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Emily Wong @emilybethwong.bsky.social · 21/08/2025

We are hiring! Please circulate in your networks. Join us in beautiful warm and wonderful KZN to answer some important questions about asymptomatic / subclinical TB. #TBsky #IDsky 🧪

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Joanne Flynn @joanneflynn19.bsky.social · 20/08/2025

We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine

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Alissa Rothchild @alissarothchild.bsky.social · 18/08/2025

Happy to share our new pre-print, led by PhD student Linh Pham! We examine inhibition of MHC II expression by NRF2 during Mtb infection and its impact on innate-adaptive crosstalk. Special thanks to the Behar lab who helped us set up a T cell co-culture system for the project! #TB #immunology

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Max Kozlov @maxkozlov.bsky.social · 15/07/2025

NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding. NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.

nature.com

Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities

The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.

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Max Gutierrez @maxgg.bsky.social · 16/06/2025

‼️ Save the date! ‼️ Tuberculosis: Understanding the Disease Across Scales Keystone 2026 on March 23-26 in Cape Town, South Africa 🇿🇦 Very excited to organise this meeting with Digby, Bree and Margarida Short Talk Abstract Deadline: Nov. 24, 2025 www.keystonesymposia.org/conferences/...

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Stand Up for Science! @standupforscience.net · 10/06/2025

WOW!.. 8500+ supporting cast heroes (that's us!) have already signed our Letter of Support for the brave NIH heroes who laid down their case in the historic #BethesdaDeclaration. Add your name here actionnetwork.org/forms/add-na... & stand up to save science & health in America. #StandUpForScience

actionnetwork.org

ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff

Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.

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Joshua Weitz @joshuasweitz.bsky.social · 31/05/2025

How bad will it be? Catastrophic. Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come. But, this is the WH's *proposed* budget. Speak up now before it is too late. (inflation adjusted $-s below)

NSF, NASA and NIH budgets per year, inflation adjusted from 2000-2025 along with the proposed cuts. NSF includes research component only. Massive cuts across all sectors, well below support spanning 25 years.

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Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 17/05/2025

There’s been some “advice” coming from some quarters for scientists not to focus on DEI-related funding cuts. I wholly reject this concept. Cutting programs designed to reduce science and healthcare disparities is as detrimental to science as anything else, both morally and functionally.

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Jeremy Berg @jeremymberg.bsky.social · 16/05/2025

New NIH Notice "expiring" a large number of funding opportunities because "We have identified a number of Notices of Funding Opportunities (NOFOs) that were not expired or reissued as indicated in the implementation plan outlined in NOT-OD-24-085." grants.nih.gov/grants/guide...

grants.nih.gov

NOT-OD-25-113: Notice of Early Expiration of Notices of Funding Opportunities Related to the Simplified Review Framework for NIH Research Grant Applications

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Early Expiration of Notices of Funding Opportunities Related to the Simplified Review Framework for NIH Resea...

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Jeremy Berg @jeremymberg.bsky.social · 23/04/2025

ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n

media.tenor.com

the word alert is in a purple circle

ALT: the word alert is in a purple circle

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Jeremy Berg @jeremymberg.bsky.social · 23/04/2025

Updated funding curves... Data downloaded today, but plotted through 4/15 to correct for NIH Reporter lag time). New and Competitive Renewal Awards first Awards being made but the rate remains lower than normal 1/2

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Chronicle of Higher Education @chronicle.com · 15/04/2025

Faculty senates at Rutgers University, the University of Nebraska at Lincoln, the University of Indiana at Bloomington, and the University of Massachusetts at Amherst have passed resolutions calling for the creation of a mutual-defense compact. chroni.cl/4cBFrnu

chroni.cl

These Faculty Senates Are Trying to Band Together to Stand Up to Trump

The idea of a compact among institutions is based on the idea that there’s strength in numbers, and it comes amid frustration that few presidents are speaking out against the administration’s actions ...

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Rep. Jim McGovern @repmcgovern.bsky.social · 14/04/2025

I'm taking action following the Trump administration's sudden revocation of international student visas in MA-02. Their actions are unconstitutional, unconscionable, and unprecedented. We need answers. Read more: mcgovern.house.gov/news/documen...

mcgovern.house.gov

Press Releases | Congressman Jim McGovern

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Journal of Clinical Investigation @jci.org · 10/04/2025

An exciting finding for the TB community! Erwin Schurr & team show people with HIV who are resistant to infection from Mycobacterium tuberculosis display activated alveolar macrophages and increased numbers of alveolar poly-cytotoxic T cells: buff.ly/xJ42sfP

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Alissa Rothchild @alissarothchild.bsky.social · 08/04/2025

Cancellation of this TB "moonshot" would be devastating to the #TB research community, further reducing any chance for novel and innovative therapies to contain the global epidemic. On a personal note, I've learned so much from this amazing team. Just heartbreaking. #TBsky #Immunosky

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Carl Zimmer @carlzimmer.com · 01/04/2025

"This will go down as one of the darkest days in modern scientific history." Story on the decimation of NIH by @maxkozlov.bsky.social www.nature.com/articles/d41...?

nature.com

‘One of the darkest days’: NIH purges agency leadership amid mass layoffs

In shock move, four institute directors at the US biomedical agency are removed from their posts.

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Alissa Rothchild @alissarothchild.bsky.social · 02/04/2025

Inspiring words tonight by Cory Booker. He’s touched on so many critical topics, but I’m so proud that in his final hour he is specifically calling out the importance and power of NIH-funded research.

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Sen. Cory Booker @booker.senate.gov · 01/04/2025

I’ve taken the Senate floor and will speak for as long as I’m physically able to lift the voices of Americans who are being harmed and not being heard in this moment of crisis. Watch here:

youtube.com

Live: Speaking on Trump, Musk, and America’s Moral Moment on the Senate Floor | Senator Cory Booker

YouTube video by Senator Cory Booker

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Dave Levitan @davelevitan.bsky.social · 01/04/2025

NEW: Per a source with knowledge, in a "bloadbath" of firings, communications, legislative, and acquisitions staff at NIH's National Institute of Allergy and Infectious Diseases are gone.

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