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Alissa Rothchild

@alissarothchild.bsky.social
1.9K followers 1.2K following 57 posts

UMass Amherst Assistant Professor | alveolar macrophage and TB immunologist | transcriptome wrangler | New England bike commuter and hiker #immunology #Tuberculosis #macrophages Lab website: rothchildlab.com

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Alissa Rothchild @alissarothchild.bsky.social · 15/07/2026
🌟 We're hiring! We're looking for enthusiastic and innovative postdoctoral fellows who are passionate about #immunology and #InfectiousDisease to join our collaborative team at UMass Amherst! #AlveolarMacrophages #TB #lung #InnateImmunity Apply now! careers.umass.edu/jobs/post-do...
careers.umass.edu
Post Doctoral Research Associate - Rothchild Lab - Amherst, Massachusetts, United States
Title: Post Doctoral Research Associate - Rothchild Lab Executive Area: Academic Affairs College/School/MBU: College of Natural Sciences Department: Veterinary & Animal Sciences Work Location: Amh...
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Alissa Rothchild @alissarothchild.bsky.social · 05/06/2026
Thrilled to see our story led by graduate student, Linh Pham, out in print! Linh's work reveals how #NRF2 impedes innate-adaptive crosstalk during #TB infection by inhibiting alveolar #macrophage MHC II expression. www.cell.com/cell-reports...
cell.com
NRF2-mediated inhibition of alveolar macrophage MHC II expression during Mycobacterium tuberculosis infection
Pham et al. show that, during Mycobacterium tuberculosis infection, NRF2 activation in alveolar macrophages inhibits MHC II but not MHC I, leading to dampening of antigen presentation and CD4+ T cell ...
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Stand Up for Science! @standupforscience.net · 31/05/2026
What does the new OMB proposal mean for science? How can we STOP VOUGHT and SAVE SCIENCE together? All of these questions and more to be discussed at the Emergency Science Meeting on June 2nd, 4PM ET, hosted by Stand Up for Science! Register at the link in our bio, or go here: zurl.co/g3vTZ
The graphic contains photos of speakers Prof. Timothy Snyder, U. of Toronto, Author of On Tyranny, Dr. Carolyn Bertozzi, Standford U. Nobel Laureate 2022, Amb. Norman Eisen, Democracy Defeders, and Dr. Elizabeth Ginexi, 20 yr NIH Veteren, "AND MORE..." to speak. The graphic reads: "TUESDAY JUNE 2nd 4PM ET/1PM PT, All welcome for the SUFS EMERGENCY SCIENCE MEETING, VIRTUAL AND ACCESSIBLE, What does the new OMB proposal mean for science? How can we STOP VOUGHT and SAVE SCIENCE together? REGISTER HERE: https://zurl.co/oCIDw, LINK IN BIO".
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Peter Chien @chienlab.bsky.social · 19/05/2026
We are hiring! Focus is on colleagues interested in protein homeostasis and human disease. Priority reviewing starts mid-June and will continue on a rolling basis. Here is the ad, hit me up if you have questions! careers.umass.edu/jobs/assista...
careers.umass.edu
Assistant Professor of Biochemistry - Protein Homeostasis - Amherst, Massachusetts, United States
Title: Assistant Professor of Biochemistry - Protein Homeostasis Executive Area: Academic Affairs College/School/MBU: College of Natural Sciences Department: Biochemistry/Molecular Biology Work Locati...
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Jeremy Berg @jeremymberg.bsky.social · 11/05/2026
Open letter calling for the reinstatement of the National Science Board. This letter is from leaders of the National Academies Note: This does not refer to the leaders on paper such as presidents of the NAS, NAM, and NAE. www.standupforscience.net/nasem-letter... @standupforscience.net
standupforscience.net
NASEM Open Letter to Congress demanding the restoration of the NSB — STAND UP FOR SCIENCE
Support NASEM's open letter to Congress by signing your endorsement now!
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Alissa Rothchild @alissarothchild.bsky.social · 28/03/2026
#NoKings Amherst, MA
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Jeremy Berg @jeremymberg.bsky.social · 13/03/2026
Following @joshuasweitz.bsky.social post and discussions with him and the Vox story, I have estimated R01 success rates for each NIH institute and center with enough awards for this to be meaningful. A long 🧵... 1/25
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Alissa Rothchild @alissarothchild.bsky.social · 12/03/2026
👏 🎉 Congratulations to Dr. Pamelia Lim (@pamelialim.bsky.social) on her outstanding thesis defense yesterday! Couldn't be more proud as a PI to have our first PhD student in the lab pass this milestone! What a bright future ahead for Dr. Lim! ✨
Celebrating Pamelia's thesis defense.
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Daniel L. Barber, PhD @danbarberphd.bsky.social · 05/12/2025
What we’ve got here is failure to communicate - some macrophages you just can’t reach! Multiple features of granulomas limit effective T cell:MΦ interactions, posing a major barrier for vaccine-mediated protection. Check out our new review! onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
<em>Journal of Internal Medicine</em> | Wiley Online Library
Tuberculosis (TB) remains a leading infectious cause of morbidity and mortality, and the development of a new, highly effective vaccine would have a tremendous beneficial impact on global health. Alt....
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Joanne Flynn @joanneflynn19.bsky.social · 04/12/2025
Hey friends. I’m looking for a postdoc interested in studying host-pathogen interactions and immunology of tuberculosis. Send me some good people! We have a great group here! Email me joanne@pitt.edu. Thanks!
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Alissa Rothchild @alissarothchild.bsky.social · 20/11/2025
Don't wait to apply! The deadline is coming up soon... Come join us! Western Mass is a fantastic place to do science!
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Alissa Rothchild @alissarothchild.bsky.social · 12/11/2025
Happy to share our latest publication in collaboration with @mcampomd.bsky.social, Kim Dill-McFarland, and Tom Hawn, where we perform a cross-species analysis of human and murine AM and MDM responses to Mtb! academic.oup.com/immunohorizo... #TBsky #Immunosky (1/5)
academic.oup.com
Shared and distinct responses of human and murine alveolar macrophages and monocyte-derived macrophages to Mycobacterium tuberculosis
Abstract. Macrophages are important sites of bacterial replication and host immune responses during Mycobacterium tuberculosis (Mtb) infection with distinc
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Journal of Experimental Medicine @jem.org · 04/11/2025
First impressions count in #TB. Andrea Cooper @uniofleicester.bsky.social discusses studies by @wjbranchett.bsky.social et al. (rupress.org/jem/article/...) and @bengern.bsky.social et al. (rupress.org/jem/article/...), in Insights: rupress.org/jem/article/...
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Elizabeth Warren @warren.senate.gov · 18/10/2025
Donald Trump is weak. He’s a bully. And when we won’t bow down to kings or to bullies, they start to lose their power. The American people do not bow down.
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Indivisible ❌👑 @indivisible.org · 18/10/2025
😍 Boston, you are beautiful. #NoKings
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Alissa Rothchild @alissarothchild.bsky.social · 15/10/2025
🚨Job posting! #UMassAmherst Department of Veterinary and Animal Sciences is hiring a TT faculty member in #Immunology. Both fundamental and translational areas considered. Please spread the word! careers.umass.edu/amherst/en-u...
careers.umass.edu
Details - Assistant Professor - Immunology | Human Resources | UMass Amherst
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Kristen DeAngelis 🏳️‍🌈🏳️‍⚧️🍉 @kristenobacter.bsky.social · 02/10/2025
UMass Amherst Microbiology is hiring a tenure-track virologist. Come work with me! 🦠🧪 careers.umass.edu/amherst/en-u...
careers.umass.edu
Details - Assistant Professor - Virology | Human Resources | UMass Amherst
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Emily Wong @emilybethwong.bsky.social · 21/08/2025
We are hiring! Please circulate in your networks. Join us in beautiful warm and wonderful KZN to answer some important questions about asymptomatic / subclinical TB. #TBsky #IDsky 🧪
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Joanne Flynn @joanneflynn19.bsky.social · 20/08/2025
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
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Alissa Rothchild @alissarothchild.bsky.social · 18/08/2025
Happy to share our new pre-print, led by PhD student Linh Pham! We examine inhibition of MHC II expression by NRF2 during Mtb infection and its impact on innate-adaptive crosstalk. Special thanks to the Behar lab who helped us set up a T cell co-culture system for the project! #TB #immunology
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John Green @johngreensbluesky.bsky.social · 18/07/2025
Tragically, the NIH is finding any reason it can to cancel grants, including critical research into the nature and function of mycobacterium tuberculosis. www.washingtonpost.com/science/2025...
washingtonpost.com
Trump officials halt ‘dangerous’ research, overriding NIH career scientists
The Trump administration’s actions on NIH gain-of-function research have raised concerns among scientists, who argue the move could block experiments that are safe and potentially lead to new treatmen...
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Max Kozlov @maxkozlov.bsky.social · 15/07/2025
NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding. NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.
nature.com
Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities
The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.
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Max Gutierrez @maxgg.bsky.social · 16/06/2025
‼️ Save the date! ‼️ Tuberculosis: Understanding the Disease Across Scales Keystone 2026 on March 23-26 in Cape Town, South Africa 🇿🇦 Very excited to organise this meeting with Digby, Bree and Margarida Short Talk Abstract Deadline: Nov. 24, 2025 www.keystonesymposia.org/conferences/...
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Stand Up for Science! @standupforscience.net · 10/06/2025
WOW!.. 8500+ supporting cast heroes (that's us!) have already signed our Letter of Support for the brave NIH heroes who laid down their case in the historic #BethesdaDeclaration. Add your name here actionnetwork.org/forms/add-na... & stand up to save science & health in America. #StandUpForScience
actionnetwork.org
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
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Joshua Weitz @joshuasweitz.bsky.social · 31/05/2025
How bad will it be? Catastrophic. Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come. But, this is the WH's *proposed* budget. Speak up now before it is too late. (inflation adjusted $-s below)
NSF, NASA and NIH budgets per year, inflation adjusted from 2000-2025 along with the proposed cuts. NSF includes research component only. Massive cuts across all sectors, well below support spanning 25 years.
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Colette Delawalla, PhD @cdelawalla.bsky.social · 29/05/2025
Delighted to see this piece with Victor Ambros, @carlbergstrom.com, Carol Greider, @michaelemann.bsky.social, and @briannosek.bsky.social in the wild. Trump’s new ‘gold standard’ rule will destroy American science as we know it @standupforscience.bsky.social www.theguardian.com/commentisfre...
theguardian.com
Trump’s new ‘gold standard’ rule will destroy American science as we know it | Colette Delawalla
The new executive order allows political appointees to undermine research they oppose, paving the way to state-controlled science
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Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 17/05/2025
There’s been some “advice” coming from some quarters for scientists not to focus on DEI-related funding cuts. I wholly reject this concept. Cutting programs designed to reduce science and healthcare disparities is as detrimental to science as anything else, both morally and functionally.
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Jeremy Berg @jeremymberg.bsky.social · 16/05/2025
New NIH Notice "expiring" a large number of funding opportunities because "We have identified a number of Notices of Funding Opportunities (NOFOs) that were not expired or reissued as indicated in the implementation plan outlined in NOT-OD-24-085." grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-25-113: Notice of Early Expiration of Notices of Funding Opportunities Related to the Simplified Review Framework for NIH Research Grant Applications
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Early Expiration of Notices of Funding Opportunities Related to the Simplified Review Framework for NIH Resea...
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Alissa Rothchild @alissarothchild.bsky.social · 25/04/2025
Congratulations @payalyokota.bsky.social! Fantastic work!
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Jeremy Berg @jeremymberg.bsky.social · 23/04/2025
ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n
media.tenor.com
the word alert is in a purple circle
ALT: the word alert is in a purple circle
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Jeremy Berg @jeremymberg.bsky.social · 23/04/2025
Updated funding curves... Data downloaded today, but plotted through 4/15 to correct for NIH Reporter lag time). New and Competitive Renewal Awards first Awards being made but the rate remains lower than normal 1/2
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Chronicle of Higher Education @chronicle.com · 15/04/2025
Faculty senates at Rutgers University, the University of Nebraska at Lincoln, the University of Indiana at Bloomington, and the University of Massachusetts at Amherst have passed resolutions calling for the creation of a mutual-defense compact. chroni.cl/4cBFrnu
chroni.cl
These Faculty Senates Are Trying to Band Together to Stand Up to Trump
The idea of a compact among institutions is based on the idea that there’s strength in numbers, and it comes amid frustration that few presidents are speaking out against the administration’s actions ...
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Rep. Jim McGovern @repmcgovern.bsky.social · 14/04/2025
I'm taking action following the Trump administration's sudden revocation of international student visas in MA-02. Their actions are unconstitutional, unconscionable, and unprecedented. We need answers. Read more: mcgovern.house.gov/news/documen...
mcgovern.house.gov
Press Releases | Congressman Jim McGovern
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Journal of Clinical Investigation @jci.org · 10/04/2025
An exciting finding for the TB community! Erwin Schurr & team show people with HIV who are resistant to infection from Mycobacterium tuberculosis display activated alveolar macrophages and increased numbers of alveolar poly-cytotoxic T cells: buff.ly/xJ42sfP
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Alissa Rothchild @alissarothchild.bsky.social · 08/04/2025
Cancellation of this TB "moonshot" would be devastating to the #TB research community, further reducing any chance for novel and innovative therapies to contain the global epidemic. On a personal note, I've learned so much from this amazing team. Just heartbreaking. #TBsky #Immunosky
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Alissa Rothchild @alissarothchild.bsky.social · 05/04/2025
Greenfield, MA #HandsOff #SocialJusticeSingout Standing room only!
Inside All Souls Church in Greenfield MA
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Carl Zimmer @carlzimmer.com · 01/04/2025
"This will go down as one of the darkest days in modern scientific history." Story on the decimation of NIH by @maxkozlov.bsky.social www.nature.com/articles/d41...?
nature.com
‘One of the darkest days’: NIH purges agency leadership amid mass layoffs
In shock move, four institute directors at the US biomedical agency are removed from their posts.
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Alissa Rothchild @alissarothchild.bsky.social · 02/04/2025
Inspiring words tonight by Cory Booker. He’s touched on so many critical topics, but I’m so proud that in his final hour he is specifically calling out the importance and power of NIH-funded research.
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Sen. Cory Booker @booker.senate.gov · 01/04/2025
I’ve taken the Senate floor and will speak for as long as I’m physically able to lift the voices of Americans who are being harmed and not being heard in this moment of crisis. Watch here:
youtube.com
Live: Speaking on Trump, Musk, and America’s Moral Moment on the Senate Floor | Senator Cory Booker
YouTube video by Senator Cory Booker
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Dave Levitan @davelevitan.bsky.social · 01/04/2025
NEW: Per a source with knowledge, in a "bloadbath" of firings, communications, legislative, and acquisitions staff at NIH's National Institute of Allergy and Infectious Diseases are gone.
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Igor Brodsky @brodskyigorlab.bsky.social · 29/03/2025
This is an understatement. We have already lost our scientific edge. Mass personnel cuts, lost grant support, gutting of pipeline programs, and the uncertainty about the future has already impacted our competitiveness and future generations of scientists. We just don’t see it yet. But we will.
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AAUP @aaup.org · 25/03/2025
BREAKING: The AAUP & chapters @ Harvard, Rutgers, & NYU; & the Middle East Studies Association today filed a lawsuit to block the Trump admin from carrying out arrests, detentions, & deportations of students & faculty who participate in pro-Palestinian protests & protected 1st Amendment activities.
aaup.org
AAUP, Allies Sue over Trump Policy of Arresting and Threatening to Deport Students and Faculty for Lawful Speech
The national AAUP; chapters at Harvard, Rutgers, and NYU; and the Middle East Studies Association today filed a lawsuit seeking to block the Trump administration from carrying out large-scale arrests,...
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Allie Sinclair @asinclair.bsky.social · 27/03/2025
📣 Across the U.S., cuts to federal funding for health research are projected to cause losses of $16B and 68,500 jobs. How will YOUR area be impacted? Excited to share SCIMaP, a website that our team has created to communicate the impact of funding cuts. #PsychSciSky #MedicalSky scienceimpacts.org
scienceimpacts.org
SCiMaP
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Alissa Rothchild @alissarothchild.bsky.social · 24/03/2025
It's #WorldTBDay. Let's remember that even before recent threats to #Tuberculosis funding, there was a funding gap for #TBdiagnosis, #TBtreatment, and #TBresearch. We must increase (not decrease) global health investments to fight this epidemic.
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Jeremy Berg @jeremymberg.bsky.social · 20/03/2025
Bare bones dashboard is up... (Including the first Advisory Council meeting posted in the Federal Register) jeremymberg.github.io/jeremyberg.g...
media.tenor.com
a woman says " it 's a start " while looking at the camera
ALT: a woman says " it 's a start " while looking at the camera
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The Journal of Immunology @jimmunol.bsky.social · 10/03/2025
Congratulations @pamelialim.bsky.social! #ReadTheJI #immunology
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Alissa Rothchild @alissarothchild.bsky.social · 16/03/2025
This would be truly devastating. NIH funded research in South Africa is critical in the fight again TB and HIV. Collaborating with S. African colleagues has enhanced and enriched the research in my own group. Any cuts to their research hurts us all. #TBsky
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Emily Wong @emilybethwong.bsky.social · 14/03/2025
We will keep trying to understand asymptomatic TB! #TBsky #IDsky Thankful for funding from @niaidnews.bsky.social @gatesfoundation.bsky.social @bwfund.bsky.social Very aware that the work of so many colleagues has been unjustly, illegally, tragically halted. We will press on as long as we can.
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Pamelia Lim @pamelialim.bsky.social · 05/03/2025
I’m so happy for my first post on Bluesky to be introducing my first 1st author paper! We show that alveolar macrophage inflammatory cytokine production to low dose LPS is enhanced by IFN-b due to lack of c-Maf/IL10 production. Download, share, and support science!! academic.oup.com/jimmunol/art...
academic.oup.com
Absence of c-Maf and IL-10 enables type I IFN enhancement of innate responses to LPS in alveolar macrophages
Abstract. Alveolar macrophages (AMs) are lung-resident myeloid cells and airway sentinels for inhaled pathogens and environmental particles. While AMs can
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