The Yang Lab at Rutgers New Jersey Medical School seeks to understand the molecular mechanisms underlying the pathogenesis and treatment of chronic and infectious diseases. We develop approaches for a...

Advances in artificial intelligence (AI) and synthetic biology are transforming biological research and biotechnology. These fields are for the first …

The Center Emerging and Re-emerging Pathogens and the Public Health Research Institute at New Jersey Medical School, Rutgers Biomedical and Health Sciences, located in Newark, NJ, invites applications...

Iron (Fe) is an essential nutrient for S. aureus survivability and pathogenesis, but excess Fe can catalyze the formation of toxic oxygen radicals, em…

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

When bacteria are under energy stress – burning more energy than they produce, it increases their chances of developing antibiotic resistance. A new study offers new insight into how antibiotic...

The bactericidal action of some antibiotics is associated with increased ATP consumption, cellular respiration, and reactive oxygen species formation. Here, Li et al. show that constitutive hydrolysis of ATP and NADH (or ‘bioenergetic stress’) potentiates the evolution of antibiotic resistance and persistence in E. coli.

New Jersey Medical School study finds metabolic stress drives antibiotic tolerance and speeds resistance.

The bactericidal action of some antibiotics is associated with increased ATP consumption, cellular respiration, and reactive oxygen species formation. Here, Li et al. show that constitutive hydrolysis...

This page highlights recent articles on all aspects of bacteriology, mycology, parasitology and virology, covering the biology of pathogens, host-pathogen ...

Rutgers Health study uncovers vulnerabilities in drug-resistant TB, offering hope for improved treatments.

Multidrug-resistant (MDR) tuberculosis threatens global control of tuberculosis disease. Here, the authors investigate mechanisms underlying the collateral sensitivity of MDR Mycobacterium tuberculosi...