Sign in

Alistair Forrest

@alforrest.bsky.social
994 followers 1.4K following 65 posts

Head of the Systems Biology and Genomics Lab at the Harry Perkins Institute of Medical Research, University of Western Australia #FANTOM5 #transcriptomics #spatial #cellcommunication #ovariancancer #bioinformatics #singlecell

PostsRepliesMedia
Alistair Forrest @alforrest.bsky.social · 02/09/2026
Join a truly global and inclusive #SingleCell community at #HCA2026Asia 🌏Registrants from 28 countries 👩‍🔬30 female and 👨‍🔬34 male speakers (10 student, 15 EMCR and 37 senior) Speakers: tinyurl.com/7zy8x3ex Submit your posters by September 13: tinyurl.com/2b6rcst4 @humancellatlas.org
000
Alistair Forrest @alforrest.bsky.social · 10/08/2026
Submit a poster for #HCA2026Asia!! Poster abstracts remain open until 13 September, and submissions will be accepted until venue capacity is reached, so don't wait too long! #SingleCell #SpatialTranscriptomics #HumanCellAtlas events.humancellatlas.org/2026asia/abs...
000
Alistair Forrest @alforrest.bsky.social · 29/06/2026
🦘 Hop to it! Reminder: Oral abstracts for #HCA2026Asia close this Friday. 🎤 30 talks available, including 15 for students and early-career researchers. #SingleCell #SpatialTranscriptomics #HumanCellAtlas events.humancellatlas.org/2026asia/abs...
010
Alistair Forrest @alforrest.bsky.social · 17/06/2026
Building a truly global and inclusive #SingleCell community at #HCA2026Asia. So far: 🌏 Registrants from 25 countries ⚖️ 10 female and 9 male invited speakers 🎓 30 speaking opportunities, including 15 dedicated to students and ECRs Submit your abstract: events.humancellatlas.org/2026asia/abs...
011
Alistair Forrest @alforrest.bsky.social · 05/06/2026
Want to give a talk at #HCA2026Asia? 🎤 30 oral presentations will be selected from submitted abstracts, including 15 for students and early-career researchers. 📅 Oral abstract deadline: 3 July 2026 events.humancellatlas.org/2026asia/abs... #SingleCell #SpatialTranscriptomics #HumanCellAtlas
000
Alistair Forrest @alforrest.bsky.social · 03/06/2026
Welcoming Anunya Opasawatchai from Mahidol Uni to #HCA2026Asia! #SingleCell #Immunology to map why individuals respond differently to vaccines and infectious diseases. Join us in Fremantle: events.humancellatlas.org/2026asia #HumanCellAtlas #SystemsImmunology Publications: tinyurl.com/ybsj2kyr
110
Alistair Forrest @alforrest.bsky.social · 29/05/2026
Welcoming Yun Xia from Nanyang Technological University to #HCA2026Asia! Advancing #StemCells and #Organoids to model kidney development and disease. Join us in Fremantle: events.humancellatlas.org/2026asia #RegenerativeMedicine #KidneyResearch #HumanCellAtlas Publications: tinyurl.com/3mue7any
020
Alistair Forrest @alforrest.bsky.social · 25/05/2026
Welcoming Nguyen Thuy Thuong Thuong from @oucru.bsky.social to #HCA2026Asia! Applying new #single_cell approaches to understand tuberculosis. Join us in Fremantle: events.humancellatlas.org/2026asia #TB #InfectiousDisease #HumanCellAtlas Publications: tinyurl.com/cjm25w52
020
Alistair Forrest @alforrest.bsky.social · 20/05/2026
Welcoming @aruthak.bsky.social to #HCA2026Asia! Advancing #SpatialBiology and #PrecisionMedicine. See recent whole-transcriptome spatial profiling of lung cancer TMAs. tinyurl.com/4ekx5aep Join us in Fremantle: events.humancellatlas.org/2026asia Publications: tinyurl.com/4utxupn9
021
Alistair Forrest @alforrest.bsky.social · 17/05/2026
Welcoming @em6wong.bsky.social from @victorchanginst.bsky.social to #HCA2026Asia @snowmedical.bsky.social fellow #TranscriptionalRegulation #ComparativeGenomics #enhancers #Bioinformatics Join us in Fremantle: events.humancellatlas.org/2026asia #HumanCellAtlas Publications: tinyurl.com/3nyrj8cv
020
Alistair Forrest @alforrest.bsky.social · 14/05/2026
Welcoming Jian Yang from Westlake University to #HCA2026Asia Leader in #StatisticalGenetics now applying #spatial to mapping of cells for complex traits tinyurl.com/w3yvd2vw Join us in Fremantle: events.humancellatlas.org/2026asia #HumanCellAtlas Publications: tinyurl.com/bda3cdwx
040
Alistair Forrest @alforrest.bsky.social · 12/05/2026
Hop to it! 🦘 Early bird registration closes June 1 for #HCA2026Asia. 30 talks will be selected from submitted abstracts, including 15 spots for students and early career researchers. events.humancellatlas.org/2026asia/abs... #SingleCell #Genomics #HumanCellAtlas
000
Alistair Forrest @alforrest.bsky.social · 11/05/2026
Welcoming Ruby Huang from @ntu-taiwan.bsky.social to #HCA2026Asia! Advancing #Genomics, #SpatialBiology and #EMT in #Ovarian_cancer. Join us in Fremantle: events.humancellatlas.org/2026asia Publications: tinyurl.com/ywtc7kub
010
Alistair Forrest @alforrest.bsky.social · 08/05/2026
Welcoming Ryan Lister from @perkinsinstitute.bsky.social and UWA to #HCA2026Asia! A pioneer in #epigenetics, #genomics, #synthetic_biology Join us in Fremantle: events.humancellatlas.org/2026asia Publications: tinyurl.com/kbdjb5x5
030
Alistair Forrest @alforrest.bsky.social · 07/05/2026
This is a numbat. Western Australia’s striped marsupial. Also the namesake of the Kharchenko Lab's single-cell CNV tool “Numbat”. Peter Kharchenko is joining us for #HCA2026Asia in Fremantle this November. events.humancellatlas.org/2026asia REGISTER NOW!! #SingleCell #Genomics #HumanCellAtlas
010
Alistair Forrest @alforrest.bsky.social · 04/05/2026
Welcoming @seyhanyazar.bsky.social from @garvaninstitute.bsky.social to #HCA2026Asia! A leader in #SingleCell #eQTLs to uncover mechanisms of autoimmune disease. Join us in Fremantle: events.humancellatlas.org/2026asia Publications: tinyurl.com/t5cbv9d7
010
Alistair Forrest @alforrest.bsky.social · 01/05/2026
Be quick like a quokka. Early bird registration for #HCA2026Asia closes June 1. Don’t miss the discount → events.humancellatlas.org/2026asia Even the little ones know a good deal when they see one (Student & ECR discounts available!!) #quokka www.rottnestisland.com/see-do/wildl...
000
Alistair Forrest @alforrest.bsky.social · 01/05/2026
Welcoming Woong-Yang Park to #HCA2026Asia! Pioneering #SingleCell #Genomics #Spatialtranscriptomics to study the TME. Join us in Fremantle in November: events.humancellatlas.org/2026asia All publications: tinyurl.com/yc362aud
000
Alistair Forrest @alforrest.bsky.social · 27/04/2026
Be quick like a quokka. Early bird registration for #HCA2026Asia closes June 1. Don’t miss the discount → events.humancellatlas.org/2026asia #quokka www.rottnestisland.com/see-do/wildl...
031
Alistair Forrest @alforrest.bsky.social · 27/04/2026
Welcoming @thewulab to #HCA2026Asia! Angela Wu (HKUST) is advancing #SingleCell #genomics and #microfluidics to build innovative multi-omic platforms. Join us in Fremantle this November: events.humancellatlas.org/2026asia #HumanCellAtlas All publications: tinyurl.com/4x7khwbt
000
Reposted by Alistair Forrest
Vanja @halfacrocodile.bsky.social · 11/04/2026
1/10 Did you know that molecular phenotypes of human skeletal muscles are vastly different? Meet FANTOMUS, the skeletal muscles promoterome-proteome atlas: doi.org/10.64898/202... made with @andreybuyan.bsky.social @nikitagryzunov.bsky.social @alforrest.bsky.social @sevamakeev.bsky.social
165
Alistair Forrest @alforrest.bsky.social · 10/04/2026
Welcoming @KharchenkoLab to #HCA2026Asia! A leader in #SingleCell #Genomics. Checkout latest on segmentation doublets in #spatial data www.nature.com/articles/s41... Join us in Fremantle in November events.humancellatlas.org/2026asia #HumanCellAtlas All publications: tinyurl.com/22vk2uss
000
Alistair Forrest @alforrest.bsky.social · 07/04/2026
Welcoming Hae-Ock Lee to #HCA2026Asia! Applying #SingleCell #Genomics to lung cancer metastasis www.nature.com/articles/s41... and ICT elifesciences.org/articles/98366 Join us in Fremantle in Nov events.humancellatlas.org/2026asia #HumanCellAtlas All publications: tinyurl.com/mtj7xms9
000
Alistair Forrest @alforrest.bsky.social · 03/04/2026
Welcoming Fuchou Tang to #HCA2026Asia! A true pioneer in #SingleCell #Genomics. From first scRNA-seq www.nature.com/articles/nme... to scHiC www.nature.com/articles/s41... Join us in Fremantle in November events.humancellatlas.org/2026asia #HumanCellAtlas All publications: tinyurl.com/4jstyd3e
011
Alistair Forrest @alforrest.bsky.social · 11/03/2026
Excited to share currently confirmed speakers for HCA Asia 2026 (lnkd.in/gEQPj3Gk)! #SingleCell #Genomics #SpatialBiology #SpatialOmics #HumanCellAtlas #SingleCell #transcriptomics #multiomics #Spatial_transcriptomics @ozsinglecell.bsky.social @lornegenome.bsky.social
142
Alistair Forrest @alforrest.bsky.social · 10/02/2026
Registration is now open for HCA Asia in Fremantle. Come make friends with our nearby neighbours. Many talking slot for EMCRs! @ozsinglecell.bsky.social @lornegenome.bsky.social #SingleCell #transcriptomics #multiomics #Spatial_transcriptomics
010
Reposted by Alistair Forrest
Human Cell Atlas @humancellatlas.org · 28/01/2026
Registration for the HCA Asia Meeting on 2-4 November, 2026 is now open! The #HCA2026Asia meeting will be held in Perth, Australia, and online, and is hosted by @alforrest.bsky.social. Please register at buff.ly/gADDEnC 🖥️ 🧬 #Genomics #SingleCell #Spatial #HumanCellAtlas
133
Reposted by Alistair Forrest
Alistair Forrest @alforrest.bsky.social · 31/10/2025
connectomeDB2025: Quality matters! ✅3,579 ligand-receptor pairs supported by 2,803 papers ✅14 vertebrates ❌ >2,900 unsupported pairs from other DBs excluded connectomedb.org academic.oup.com/nar/advance-... @JARamilowski @sakura_maezono @rui_hou_ @weitao_lin @yen_yeow + team
A a figure showing comparison of connectomeDB2025 to other ligand-receptor pair databases.
193
Alistair Forrest @alforrest.bsky.social · 15/12/2025
First ride and ocean swim of the year in the big blue antidepressant. There's beauty out there, fish, seaweed and seagrass.. and so far no stingers!
030
Alistair Forrest @alforrest.bsky.social · 07/12/2025
Australia’s hyper-competitive grant system is harming the very researchers working to improve our nation’s health. Chronic stress, relationship breakdowns, depression, burnout, self-medication, and, tragically, suicide are part of our sector's reality. www.linkedin.com/posts/alforr...
linkedin.com
Australia's hyper competitive grant system, and the chronic job insecurity it creates, is harming the very researchers who are working to improve the nation's health. The people striving to fi...
Australia's hyper competitive grant system, and the chronic job insecurity it creates, is harming the very researchers who are working to improve the nation's health. The people striving to find cures...
020
Alistair Forrest @alforrest.bsky.social · 07/12/2025
Chances are you're about to lose. Science funding in Australia is now a gamble with terrible odds. #NHMRC Ideas success rates have hit 8.1% nationally, <4% in WA. Brilliant colleagues are leaving or quitting. We need change. www.linkedin.com/posts/alforr...
linkedin.com
For those outside of Australia this is an anti-gambling advert. I am posting this because funding for science in Australia is at a crisis and for many in the research sector we are gambling with our… ...
For those outside of Australia this is an anti-gambling advert. I am posting this because funding for science in Australia is at a crisis and for many in the research sector we are gambling with our f...
070
Reposted by Alistair Forrest
Jenny Sinclair @jsresearchpro.bsky.social · 27/11/2025
Australia: Low ARC success rates for early career researchers sparks anger (free to read): www.researchprofessionalnews.com/rr-news-aust...
researchprofessionalnews.com
Low success rate in early career grants ‘deeply disappointing’ - Research Professional News
“Decay continues” as Australian Research Council’s Decra scheme announces 13.1 per cent success rate
022
Reposted by Alistair Forrest
Jovana Maksimovic @jovmaksimovic.bsky.social · 26/11/2025
Chelsea Mayoh at #abacbs2025: "If you're not using RNA-seq in your precision medicine program you're probably missing stuff"! Great to see @aliciao.bsky.social lab tools MINTIE, ALLsorts and TALLsorts making an appearance 🎉
0125
Alistair Forrest @alforrest.bsky.social · 26/11/2025
It's time... theconversation.com/how-the-war-...
theconversation.com
How the war was won: the campaign to stop medical research cuts
One day in April, Walter and Eliza Hall Institute of Medical Research director Douglas Hilton called his communications manager, Penny Fannin, into his office. “He said he’d heard significant cuts wer...
031
Reposted by Alistair Forrest
Izzy Jayasinghe @ijayas.bsky.social · 26/11/2025
When I took this job as the Head of a department, I never thought my job would involve consoling & moving on some of my most talented researchers at the end of each year - just bc their ARC/NHMRC grant didn’t get up. Having worked in multiple countries, I have never seen this normalised like in Aus.
2122
Reposted by Alistair Forrest
Dr Shane Huntington OAM @drshanerrr.bsky.social · 26/11/2025
The success rate for NHMRC Ideas Grants announced yesterday was just over 8%. That means 11 of every 12 people who applied got rejected. This is a culture changing level of rejection and frankly a point of national shame. This is a crisis for research. I will not rest until we see this resolved.
38832
Alistair Forrest @alforrest.bsky.social · 26/11/2025
Be kind to each other.. bad news for most coming in under embargo. We need more funding in the system...
0143
Alistair Forrest @alforrest.bsky.social · 23/11/2025
Heading to Radelaide for #ABACBS2025 . Looking forward to catch up with old friends and nerd out on bioinformatics! Checkout PhD student Peiwen Liu's poster on connectomeDB2025 (Quality matters!) connectomeDB.org
connectomedb.org
– ConnectomeDB2025
0144
Alistair Forrest @alforrest.bsky.social · 31/10/2025
connectomeDB2025: Quality matters! ✅3,579 ligand-receptor pairs supported by 2,803 papers ✅14 vertebrates ❌ >2,900 unsupported pairs from other DBs excluded connectomedb.org academic.oup.com/nar/advance-... @JARamilowski @sakura_maezono @rui_hou_ @weitao_lin @yen_yeow + team
A a figure showing comparison of connectomeDB2025 to other ligand-receptor pair databases.
193
Reposted by Alistair Forrest
ARC Tracker @arc-tracker.bsky.social · 14/07/2025
The ARC has “announced” an update on the proposed changes to its grant schemes. Key changes, in response to “nearly 350” submissions” (!) on their proposal, are 👇 More here: www.arc.gov.au/news-publica...
Black text on white background. Screenshot from ARC webpage updating us on changes, in response to community feedback, to their proposed modification to their grants system. This screenshot shows the main changes, listed on that webpage.
23521
Reposted by Alistair Forrest
ARC Tracker @arc-tracker.bsky.social · 25/02/2025
The ARC Board has proposed a major shake-up of the National Competitive Grants Program ▶️ www.arc.gov.au/engage-us/co... I've only skimmed so far, but they propose reducing 13 grant schemes to 6, with intent & scope in the table👇 Submissions are being accepted in response until 13 April. Get to it!
Table from page 25 of the proposed restructure of ARC grants. Back text on white background, with the table delineated by a dark blue header row and alternating light and very light blue rows.
136852
Reposted by Alistair Forrest
Nikolai Slavov @slavov-n.bsky.social · 11/03/2025
Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide . www.nature.com/articles/s41...
nature.com
Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide - Nature
Computational drug discovery is used to identify a 12-mer peptide derived from BRINP2 with potent anti-obesity effects that are independent of leptin, glucagon-like peptide 1 receptor and melanocortin...
042
Reposted by Alistair Forrest
Rada-Iglesias Lab @radaiglesiaslab.bsky.social · 03/03/2025
Do you have an exciting story about #enhancers or #enhanceropathies?. Then submit your abstract to the @embo.org workshop on "Enhancer mechanics and Enhanceropathies" in Denmark before is too late: the deadline for abstract submissions is in two weeks (March 17th)! meetings.embo.org/event/25-enh...
01710
Alistair Forrest @alforrest.bsky.social · 12/02/2025
Heading to #lornegenome25 #LorneCancerConference ? Looking for a computational postdoc to work on spatial and single nuclei transcriptomics of poor prognosis cancers, please DM me or see me at Lorne. We will be advertising soon. @ozsinglecell.bsky.social #LorneCancer2025 #Lorne2025
bsky.app
11012
Reposted by Alistair Forrest
Shalin H. Naik @shalinhnaik.bsky.social · 30/01/2025
@ozsinglecell.bsky.social #OzSingleCell25 has a new website www.ozsinglecell.com See the current list of invited speakers and stay tuned for registration details. Sponsors reach out to ozsinglecells@gmail.com
01511
Reposted by Alistair Forrest
Andrew G. York @andrewgyork.bsky.social · 22/11/2024
MagLOV! MagLOV is a fluorescent protein you can "turn off" with a handheld magnet, engineered by @mariaingaramo.bsky.social. We think/hope we can use it to turn arbitrary proteins (including drugs!) on and off in opaque creatures (including humans!). bsky.app/profile/addg...
320372
Reposted by Alistair Forrest
Anthony Beckhouse @antobeck.bsky.social · 13/01/2025
A little video intro into Illumina Single Cell 3' RNA Prep protocols. It has begun!! #singlecell #transcriptomics #PIPSeq #illumina
153
Reposted by Alistair Forrest
Caleb Lareau @caleblareau.bsky.social · 08/01/2025
Out today in @naturegenet.bsky.social -- PERFF-seq! With @tsionabay.bsky.social , @ronanchaligne.bsky.social, Bob Stickels, Meril Takizawa, + Ansu Satpathy, we describe this new assay to study rare populations with programmable nucleic acid cytometry. 1/n www.nature.com/articles/s41...
nature.com
Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing - Nature Genetics
Programmable Enrichment via RNA FlowFISH by sequencing (PERFF-seq) isolates rare cells based on RNA marker transcripts for single-cell RNA sequencing profiling of complex tissues, with applicability t...
416545
Reposted by Alistair Forrest
Lisa Heinke @lisaheinke.bsky.social · 14/01/2025
@nature.com wants to hear from you on the battle of David vs Goliath - aka Twitter 🐥 vs Bluesky 🦋* And if you’re reading this post I already know your answer to one of the questions 🙂‍↕️ 👉🏼 www.nature.com/articles/d41... *I’ll let you decide who’s who at this point!
nature.com
Has Bluesky replaced X for scientists? Take Nature’s poll
The research community has flocked to the social-media platform Bluesky. Tell us about your experience.
0209
Alistair Forrest @alforrest.bsky.social · 10/01/2025
www.cell.com/cell/fulltex... Perturb-map - focused on receptor/ligands hypothesized to be involved in tumor-macrophage communication
cell.com
Ovarian cancer-derived IL-4 promotes immunotherapy resistance
Cancer-derived paracrine factors create distinct “neighborhoods” in the tumor microenvironment, promoting clonal selection and tumor heterogeneity. In ovarian cancer, IL-4 originating from a minority of cells within the tumor can promote immune suppression and tumor resistance to immune checkpoint blockade therapy.
060