iiinova — where your digital self keeps evolving

Alex Swarbrick @alexswarbrick.bsky.social · 30/03/2026

Vale Mike Bishop, age 90. A humble, kind, deep thinker. I was blessed to undertake my postdoc with Mike, which transformed me as a scientist. I am so grateful for his support and encouragement, and the amazing colleagues and friends I made in that time. www.nytimes.com/2026/03/22/o...

nytimes.com

J. Michael Bishop, Nobel Prize Winner for Cancer Research, Dies at 90

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Thomas R. Cox @trcox.matrixandmetastasis.com · 04/06/2025

New review paper written by Jess Chitty in the team just out in Trends in Cancer (@cp-trendscancer.bsky.social) (OpenAccess) The extracellular matrix in cancer: from understanding to targeting | → www.sciencedirect.com/science/arti... ← |

sciencedirect.com

The extracellular matrix in cancer: from understanding to targeting

Significant advances in matrix biology research have enhanced our understanding of individual matrix components and extracellular matrix (ECM) signall…

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Alex Swarbrick @alexswarbrick.bsky.social · 26/03/2026

PROSTATE CANCER ATLAS out now: scRNA-Seq on paired malignant and benign biopsies from 24 patients plus Visium & Xenium. Detailed annotation = valuable reference for the field. Describe perinueral fibroblasts and a trajectory of epithelial perturbation. Data @EGA and Cellxgene doi.org/10.1158/0008...

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Alex Swarbrick @alexswarbrick.bsky.social · 10/08/2025

Felling inspired after my visit to The Broad Institute. Brilliant science in a collaborative energised environment. Thanks @azizalkhafaji.bsky.social and Gammy Al-Eryani for hosting

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Alex Swarbrick @alexswarbrick.bsky.social · 01/08/2025

I’m looking for a PhD student to work on an exciting new collaboration with @azizalkhafaji.bsky.social at the @broadinstitute.org. Together we are using single cell long-read sequencing to understand tumour evolution and microenvironments. Hybrid computational and molecular role. 🧬

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Alex Swarbrick @alexswarbrick.bsky.social · 01/08/2025

Thankyou for hosting us! We are so impressed by the quality of the science, collaboration and facilities at @pmresearch-uhn.bsky.social. Looking forward to developing exciting new projects together

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Alex Swarbrick @alexswarbrick.bsky.social · 13/06/2025

An exciting new paper on the application of federated deep learning to pan-cancer proteomic data. Congrats to the Procan team for this achievement! Very happy to have contributed our breast cancer dataset to this important work. doi.org/10.1158/2159... www.cmrijeansforgenes.org.au/research/res...

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Alex Swarbrick @alexswarbrick.bsky.social · 13/06/2025

Today is the last day in the lab for for Marion Motard, who joined the lab for her Masters then stayed on as a research assistant. She did brilliant work on GNNs to predict gene module enrichment in histology images. She is returning to Europe, quickly offer her a job in ML/computational !

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Alex Swarbrick @alexswarbrick.bsky.social · 09/06/2025

I had a great time at the #wehispatial25 meeting. So much excellent spatial ‘omics going on in Oz. But weware the @wehi rubber chicken

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Alex Swarbrick @alexswarbrick.bsky.social · 27/03/2025

I'm chairing session ED52 "Innovative Approaches in TME Biology: From Profiling to Function" at #AACR2025. I'll present data using cellular and functional genomics to identify small molecule mediators of stromal plasticity. Also the amazing Illaria Malanchi and Nick Navin. LMK if u will be there!

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Itai Yanai @itaiyanai.bsky.social · 02/01/2025

The four basic kinds of scientific papers: 1. Noise (no claim and no evidence) 2. Resource (no claim but lots of data) 3. Conjecture (makes a claim, but no evidence) 4. Scientific advance (both makes a claim and presents evidence)

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Sara Zanivan @zanivanlab.bsky.social · 18/12/2024

If you are interested in joining our growing Lab of CAFs enthusiasts @mdanderson.bsky.social and to understand how CAF metabolism can be harnessed to modulate the immune-TME, we are looking for talented postdocs! 👇🏻 jobs.mdanderson.org/search/jobde...

jobs.mdanderson.org

Postdoctoral Fellow - Experimental Therapeutics (Zanivan Lab) at MD Anderson

MD Anderson is Hiring! Search available jobs or submit your resume now by visiting this link. Please share with anyone you feel would be a great fit.

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Alex Swarbrick @alexswarbrick.bsky.social · 16/12/2024

Wanted- *Bioinformatics Research Assistant*. Projects include generation of an international, large-scale, multi-omic breast cancer atlas and understanding response to immunotherapy in breast cancer, prostate cancer and melanoma. Great training opportunities 🧬💻 More info ⤵️ tinyurl.com/33wxkswz

tinyurl.com

Research Assistant - Bioinformatics

The Garvan Institute of Medical Research brings together world leading researchers and clinicians, collaborating locally and globally, to improve human health. Our mission is to harness all the inform...

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Alex Swarbrick @alexswarbrick.bsky.social · 12/12/2024

Jobortunities: Shortly advertising for 2 positions, both working on the Breast Cancer Atlas, in Sydney. - Wet lab research assistant: mol bio +/- pathology desirable - Comp. Research Assistant: scRNA-Seq, spatial transcriptomics and ML Details to follow, DM or email if you are a great fit.

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Eric Topol @erictopol.bsky.social · 04/12/2024

One of the alluring and theoretical strategies for extending healthspan and longevity is to rejuvenate the thymus gland, promote an intact immune system. Now there's a way to do that in aged mice. www.science.org/doi/10.1126/...

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Alex Swarbrick @alexswarbrick.bsky.social · 05/12/2024

Thanks to @aruthak.bsky.social and colleagues for the invitation to this fantastic, unique meeting #multi-omics2024. Thnx for the shoutout to the awesome @martinalexsmith.bsky.social

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Jasmine Plummer @jasmineplummer.bsky.social · 01/12/2024

When you get to be your own caricature!! Grateful to be in #oz sharing science with #friends. For those missing out #multiomics2024 is where #singlecell #spatial #omics #immunology #oncology and #precisionmedicine is where it’s at🥳

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Martin Smith @martinalexsmith.bsky.social · 02/12/2024

Yesterday, I presented our latest results mining single molecule m6A data at #multiomics2024: We see changes in m6A levels following CRISPR-cas13 knock-down of oncogenic lncRNAs that are independent of mRNA expression levels, revealing new dimensions of highly pertinent biological information

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Garvan Institute Cancer Ecosystems Program @cancerecogarvan.bsky.social · 29/11/2024

A nice explanation of the space our Cancer Ecosystems Program researchers work in - its tricky! but they are applying spatial and single cell multiomics to clinical samples and taking big steps forward towards better outcomes for patients - check out our team at www.garvan.org.au/research/str...

garvan.org.au

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Matt Sikora @mjsikora.bsky.social · 25/11/2024

Public Service Announcement: Check colorblind-compatibility in Illustrator! Under 'View', 'Proof Setup' you can selected a colorblindness type to view your image in that spectra. Click 'Proof Colors' after to remove filter. We chose pink/green, yellow/blue here for accessibility (PMID 38112643).

Screen capture of an Adobe Illustrator window in standard viewing mode (that is, without colorblind filter applied).

Screen capture of an Adobe Illustrator window with 'View' menu pulled down, showing selection of a relevant colorblindness filter being applied.

Screen capture of an Adobe Illustrator window with the previous image in a protanopia-type colorblindness mode applied.

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Johanna Joyce @johannajoyce.bsky.social · 23/11/2024

Both #Cancer #Research starter packs are now completely full! ~300 researchers, oncologists, students, postdocs, patient advocates, and organizations supporting cancer research 🧪🔬⚕️ I hope you'll find these useful to build our community here Pack 1: go.bsky.app/FEoaJMc Pack 2: go.bsky.app/6EcjWNA

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danapeer.bsky.social @danapeer.bsky.social · 22/11/2024

Truly brilliant work. Calling it a foundation model is a stretch (a mistake many people in the field make). But, the only single-cell AI model in its class that I think is worth the GPU energy expended and one that I excited to utilize. My stamp of approval. www.nature.com/articles/s41...

nature.com

A cell atlas foundation model for scalable search of similar human cells - Nature

Nature - A cell atlas foundation model for scalable search of similar human cells

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Elana Fertig, PhD @fertiglab.bsky.social · 20/11/2024

People deserve a world in which they can live in peace as themselves. What steps are people taking to ensure that in their communities, particularly as the world is going dark?

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Shalin H. Naik @shalinhnaik.bsky.social · 19/11/2024

We are ramping up our attempts to get DC1 immunotherapy into the clinic for colorectal and lung cancer. Here me talk about why DC1s are the right choice, and how WEHI and PeterMacCC will get it to clinical trial within 2 yrs. Start ~13 min in. podcasts.apple.com/au/podcast/v...

podcasts.apple.com

VAXXED: Game on, with BASE and WEHI

Podcast Episode · Phase III · 19/11/2024 · 26m

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Thomas R. Cox @trcox.matrixandmetastasis.com · 20/11/2024

Today I had the opportunity to present our ongoing translation of pan-LOX inhibitors in pancreatic cancer at the Australasian Gastrointestinal Trials Group (AGITG) Annual Scientific Meeting. Read more about this work here| → www.nature.com/articles/s43... ← |

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Itai Yanai @itaiyanai.bsky.social · 17/11/2024

Too often we spend only two weeks choosing a problem and then many years trying solving it, but this limits our potential impact. A must read for PhD students: Problem choice and decision trees in science and engineering. pubmed.ncbi.nlm.nih.gov/38608651/

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Alex Swarbrick @alexswarbrick.bsky.social · 15/11/2024

We recently released a new preprint on human localised prostate cancer biology. We used scRNA-Seq and spatial transcriptomics to dig deep into epithelial plasticity and stromal biology Led by Eva Apostolov www.biorxiv.org/content/10.1...

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