Lercher Lab — inflammatory signal integration and inflammatory memory at Heidelberg University.

Yu et al. discover that TRCR1, a tuberculosis resister-derived exosomal lncRNA, induces trained immunity via CLOCK-mediated epigenetic reprogramming. They show that mycobacterial protein MPT53 prompts...

The therapeutic potential of antigen-independent innate immune memory (IIM) is of particular relevance in the context of respiratory viruses with pandemic potential. Lercher et al. find that antiviral...

My name is Alexander Lercher, and I am currently a Postdoc in the lab of Charlie Rice at Rockefeller University in New York, and I am particularly excited about studying immune responses in the context...

My name is Alexander Lercher, and I am currently a Postdoc in the lab of Charlie Rice at Rockefeller University in New York, and I am particularly excited about studying immune responses in the context of real-world microbe exposure. Out from the lab, my biggest hobby for the past years has been to explore the

Innate immune cells that are epigenetically reprogrammed by infection can modify host responses to subsequent infections. Lercher et al. have identified epigenetic reprogramming of murine airway-resid...

This Week in Virology · Episode