The gut microbiota plays a central role in modulating both immunity and metabolism. Obesity-associated microbiota configuration is a critical driver of persistent inflammatory activation and immune...

Nature Microbiology, Published online: 25 May 2026; doi:10.1038/s41564-026-02369-5Multi-omics analysis of the plant fungal pathogen Magnaporthe oryzae reveals the mitophagy pathway regulator Cox6 as a druggable target for antifungal treatment.

Neutrophils depend on glucose for their antifungal activities. Candida albicans consumes glucose, thus posing metabolic challenges for neutrophils. Choi and colleagues show that neutrophils upregulate...

Mucosal barriers play critical roles in the interaction with commensal and pathogenic microbes. Here the authors show non-canonical IL-22 signalling results in mucosal remodelling in a murine model du...

Introduction. Colorectal cancer (CRC) is a malignant tumour in which dysbiosis of the gut microbiome is a contributing factor in the development of cancer. However, the species composition and species-specific changes in the gut microbiome related to CRC still require comprehensive investigation. Hypothesis. There is a significant difference in gut microbiome between CRC patients and healthy individuals. Aim. The microbiome-based association test methods are used for the association between the microbiome and host phenotypes, and linear discriminant analysis effect size (LEfSe) analysis is...

If confirmed in people, the finding might lead to gut-targeted therapies that could reverse cognitive decline.

Neutrophils depend on glucose for their antifungal activities. Candida albicans consumes glucose, thus posing metabolic challenges for neutrophils. Choi and colleagues show that neutrophils upregulate...

How does other types of microbe like fungi influence tumor-promoting role of Fusobacterium nucleatum? In this study, Li et al. establish that commensal fungi facilitate translocation of pro-tumor bacteria across mucus barrier to drive colorectal cancer (CRC) progression, revealing a cross-kingdom collaboration between fungi and bacteria.

Candida hijacks epithelial metabolism via glycolysis and GOT1-dependent TCA shunt, influencing antifungal defense.

Candida hijacks epithelial metabolism via glycolysis and GOT1-dependent TCA shunt, influencing antifungal defense.

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We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow-derived innate cells, e...

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The heatwave has led to red alerts being issued in parts of Italy, France, Spain, Portugal and the Balkans.