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Aize Pellón Rodríguez

@aizepellon.bsky.social
1.3K followers 454 following 69 posts

#MSCA Postdoctoral Fellow at CIC bioGUNE (Bilbao, Spain) || Host-microbe interactions || Fungal Immunology || Innate immune memory || Trained immunity || Immunometabolism || Microbiota #SinCienciaNoHayFuturo #MycoSky linktr.ee/aizepellonrodriguez

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Reposted by Aize Pellón Rodríguez
Sociedad Española de Bioquímica y Biología Molecular (SEBBM) @sebbm.bsky.social · 18/09/2026
📸 #PinacotecaSeptiembre: "Pac-Man in vivo", de Marta Palomo-Irigoyen (U. de Medicina de Viena). El tejido gástrico de ratón se transforma en un laberinto que recuerda al Pac-Man, en un entorno con pH ~1.5 👇 sebbm.es/pinacoteca-de-la-ciencia
Microscopía de fluorescencia del estómago de ratón con superposición de Pac-Man
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Reposted by Aize Pellón Rodríguez
The MRC Centre for Medical Mycology @mrccmm.bsky.social · 11/09/2026
Fungal diseases start where life happens. Fungal Disease Awareness Week is September 14-18. #ThinkFungus26 and raise awareness to help protect people from the growing impact of fungal diseases. bit.ly/4dyCy6u
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Aize Pellón Rodríguez @aizepellon.bsky.social · 06/08/2026
Happy to have contributed to this new paper published in @natmicrobiol.nature.com describing the role of IL-1 family signalling in controlling mucosal candidiasis and fungal dissemination. Congratulations to all the authors for the great work! @kingsdentistry.bsky.social @cicbiogune.bsky.social
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Toni Gabaldón @tonigabaldon.bsky.social · 10/06/2026
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature. Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis. doi.org/10.1038/s415...
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Aize Pellón Rodríguez @aizepellon.bsky.social · 03/06/2026
Happy to see this published! A fantastic collaboration with Yolanda Sanz and her team highlighting the importance of the gut microbiota and immunometabolism in obesity. Check out the paper 👉 @iatacsic.bsky.social @cicbiogune.bsky.social @anguitalab.bsky.social www.tandfonline.com/doi/full/10....
tandfonline.com
Gut microbiota and immunometabolism in obesity
The gut microbiota plays a central role in modulating both immunity and metabolism. Obesity-associated microbiota configuration is a critical driver of persistent inflammatory activation and immune...
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Reposted by Aize Pellón Rodríguez
Nature Microbiology @natmicrobiol.nature.com · 25/05/2026
Out Now! Mitophagy steps into the spotlight of fungal virulence #MicroSky
go.nature.com
Mitophagy steps into the spotlight of fungal virulence
Nature Microbiology, Published online: 25 May 2026; doi:10.1038/s41564-026-02369-5Multi-omics analysis of the plant fungal pathogen Magnaporthe oryzae reveals the mitophagy pathway regulator Cox6 as a druggable target for antifungal treatment.
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CIC bioGUNE @cicbiogune.bsky.social · 19/05/2026
#WorldIBDDay | 🧬 Hoy, 19 de mayo, Día Mundial de la EII: Crohn y colitis ulcerosa, enfermedades crónicas que afectan a ~1% de la población En #CICbioGUNE @brtaeus.bsky.social impulsamos investigación en medicina de precisión y microbiota 👉 www.cicbiogune.es/news/en-dia-...
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Cell Press Events @cellpressevents.bsky.social · 10/05/2026
Walking and talking our way through Bruges before the meeting kicks off! #CSMicrobiome2026 @cp-immunity.bsky.social l @cp-cellhostmicrobe.bsky.social @cp-trendsmicrobiol.bsky.social
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Aize Pellón Rodríguez @aizepellon.bsky.social · 07/05/2026
Next week we’re at #CSMicrobiome2026 in Bruges (BE)! 4 posters from our group on microbiota–immune interactions👇 🕒 Poster Session 2 13:15–14:45 | 11 May 📍 The View & The Foyer Come say hi! 🙂 @cicbiogune.bsky.social @anguitalab.bsky.social @cellpressevents.bsky.social
Poster showing our group's presentations schedule at the Cell Press Symposium on Host-microbiome dynamics conference in Bruges (BE).

P2.017 Iratxe Seoane – inflammation models & phloroglucinol
👉 P2.065 Naiara Gutiez – CRC & dysbiosis reversion
👉 P2.084 Eneko Santos-Fernandez – microbiota & Lyme disease protection
👉 P2.093 Aize Pellón Rodríguez – E. coli, microbiome & BM immune signatures

🕒 Poster Session 2
13:15–14:45 | 11 May
📍 The View & The Foyer
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CIC bioGUNE @cicbiogune.bsky.social · 05/05/2026
#bioGUNE_News | 🔬 #CICbioGUNE Basque Research and Technology Alliance - BRTA held the 1st Postdoc Day, bringing together postdoctoral researchers to promote scientific exchange, collaboration & career development, together with #bioGUNE_Alumni 🔗 ow.ly/AUNf50YUxnk
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Cell Host & Microbe @cp-cellhostmicrobe.bsky.social · 08/04/2026
Featured Article: Metabolic flexibility allows neutrophils to fight Candida Upon C. albicans glucose consumption, neutrophils upregulate PYGL-mediated glycogenolysis through a dectin-1/PKA axis, thus sustaining antifungal function in glucose-low tissues www.cell.com/cell-host-mi...
cell.com
Glycogen phosphorylase L confers metabolic flexibility in neutrophils to fight fungal infections in nutrient-deprived tissues
Neutrophils depend on glucose for their antifungal activities. Candida albicans consumes glucose, thus posing metabolic challenges for neutrophils. Choi and colleagues show that neutrophils upregulate...
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Reposted by Aize Pellón Rodríguez
Marc Swidergall @swidergall-lab.bsky.social · 03/04/2026
Excited to share our latest publication @natcomms.nature.com Non-canonical IL‑22 receptor signaling remodels the oral mucosal barrier during #Candida albicans immunosurveillance www.nature.com/articles/s41...
nature.com
Non-canonical IL‑22 receptor signaling remodels the oral mucosal barrier during Candida albicans immunosurveillance - Nature Communications
Mucosal barriers play critical roles in the interaction with commensal and pathogenic microbes. Here the authors show non-canonical IL-22 signalling results in mucosal remodelling in a murine model du...
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Microbiology Society @microbiologysociety.org · 01/04/2026
It's Bowel Cancer Awareness Month. Find out the differences in gut microbiome composition between colorectal cancer patients and healthy individuals in JMM: doi.org/10.1099/jmm.0.002042 #BowelCancerAwarenessMonth #JMM
doi.org
Meta-analysis of gut microbiome reveals patterns of dysbiosis in colorectal cancer patients
Introduction. Colorectal cancer (CRC) is a malignant tumour in which dysbiosis of the gut microbiome is a contributing factor in the development of cancer. However, the species composition and species-specific changes in the gut microbiome related to CRC still require comprehensive investigation. Hypothesis. There is a significant difference in gut microbiome between CRC patients and healthy individuals. Aim. The microbiome-based association test methods are used for the association between the microbiome and host phenotypes, and linear discriminant analysis effect size (LEfSe) analysis is...
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Aize Pellón Rodríguez @aizepellon.bsky.social · 01/04/2026
Nuestra compañera Naiara Gutiez estudia el papel de la microbiota intestinal y la dieta en la progresión y severidad del cáncer colorrectal, uno de los tipos de tumor más prevalentes. #DíaMundialContraElCáncerDeColon @contracancerinv.bsky.social @anguitalab.bsky.social @cicbiogune.bsky.social
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Prof Danny Altmann @daltmann.bsky.social · 19/03/2026
Memory loss is fuelled by gut microbes in ageing mice www.nature.com/articles/d41...
nature.com
Memory loss is fuelled by gut microbes in ageing mice
If confirmed in people, the finding might lead to gut-targeted therapies that could reverse cognitive decline.
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LaBella Lab @lablabella.bsky.social · 18/03/2026
Oier Etxebeste takes us on a tour through the decades of research on the role of BrlA in Aspergillus conidiation #Fungal2026
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Cell Host & Microbe @cp-cellhostmicrobe.bsky.social · 18/03/2026
Metabolic flexibility allows neutrophils to fight Candida In response to C. albicans glucose consumption, neutrophils upregulate PYGL-mediated glycogenolysis through a dectin-1/PKA axis, thus sustaining antifungal function in glucose-deprived tissues www.cell.com/cell-host-mi...
cell.com
Glycogen phosphorylase L confers metabolic flexibility in neutrophils to fight fungal infections in nutrient-deprived tissues
Neutrophils depend on glucose for their antifungal activities. Candida albicans consumes glucose, thus posing metabolic challenges for neutrophils. Choi and colleagues show that neutrophils upregulate...
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Reposted by Aize Pellón Rodríguez
Cancer Cell @cp-cancercell.bsky.social · 27/02/2026
Online Now: Candida albicans synergizes with Fusobacterium nucleatum in colorectal cancer progression via the Flo9-RadD interaction
dlvr.it
Candida albicans synergizes with Fusobacterium nucleatum in colorectal cancer progression via the Flo9-RadD interaction
How does other types of microbe like fungi influence tumor-promoting role of Fusobacterium nucleatum? In this study, Li et al. establish that commensal fungi facilitate translocation of pro-tumor bacteria across mucus barrier to drive colorectal cancer (CRC) progression, revealing a cross-kingdom collaboration between fungi and bacteria.
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Robert Arkowitz @robertarkowitz.bsky.social · 06/02/2026
www.science.org/doi/full/10....
science.org
Fungal infection drives metabolic reprogramming in epithelial cells via aerobic glycolysis and an alternative TCA cycle shunt
Candida hijacks epithelial metabolism via glycolysis and GOT1-dependent TCA shunt, influencing antifungal defense.
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CIC bioGUNE @cicbiogune.bsky.social · 05/02/2026
#bioGUNE_Research | 🦠 An international team including #CICbioGUNE @brtaeus.bsky.social shows how oral cells reprogram their metabolism in response to Candida albicans Led by @aizepellon.bsky.social, the study reveals new metabolic pathways with therapeutic potential 🔗 ow.ly/hMwR50Y9eCq
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Aize Pellón Rodríguez @aizepellon.bsky.social · 05/02/2026
We just published a new paper in Science Advances, where we uncover how #Candida albicans reprograms the metabolism of oral epithelial cells during infection. As first and corresponding author, I’m excited to share what we found — and why it matters. #Skytorial #Immunometabolism #MedMycoSky
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Laura Cooper @transitionalform.bsky.social · 21/01/2026
Our paper on the mysterious Devonian organism Prototaxites has now finally been published! See the paper here (www.science.org/doi/10.1126/...) and our explainer thread below! Prototaxites reconstruction by Matt Humpage
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CIC bioGUNE @cicbiogune.bsky.social · 15/01/2026
#bioGUNE_Research |🧬 An international study led by @arkaitzcarracedo.bsky.social Lab #CICbioGUNE @brtaeus.bsky.social, published in @nature.com, shows how polyamines help cells make decisions and protect proteins @contracancerinv.bsky.social @ciberisciii.bsky.social 🔗 ow.ly/xkuY50XWKRV
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Fernando T. Maestre @ftmaestre.bsky.social · 12/01/2026
In our latest paper, just published in @natcomms.nature.com we show that soil conditions, landscape structure & land-use change shape global soil pathogenic fungal diversity. Landscape complexity and crops increase diversity, while grass and tree cover reduce it www.nature.com/articles/s41...
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CIC bioGUNE @cicbiogune.bsky.social · 22/12/2025
#bioGUNE_Outreach | 🎙️ Microbiota y sistema inmune ➡️ ¿Pueden nuestras defensas más básicas “recordar” infecciones y ayudarnos a combatir la resistencia a los antibióticos? Descúbrelo con @aizepellon.bsky.social #CICbioGUNE @brtaeus.bsky.social #BioEnredados 🔗 cicbiogune.es/outreach/pod...
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CIC bioGUNE @cicbiogune.bsky.social · 13/10/2025
#bioGUNE_EmpoweringWomen | 🚺 Meet Naiara Gutiez This #WomenInBiosciences episode features her research on how the gut microbiota influences colorectal cancer at @anguitalab.bsky.social 💡 Discover her work towards new cancer prevention strategies! 🎥 youtu.be/VPVGXQ-YuBU?...
youtu.be
Meet Naiara Gutiez - Exploring Microbiota’s Role in Colorectal Cancer Development
YouTube video by CIC bioGUNE
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Aize Pellón Rodríguez @aizepellon.bsky.social · 02/10/2025
🚨 New paper alert! Our team at CIC bioGUNE has just published a new study in "Immunology" exploring how adjuvants can induce innate immune memory and reshape hematopoiesis. Let’s dive in 👇 #InnateMemory #TrainedImmunity #Immunology @anguitalab.bsky.social @cicbiogune.bsky.social 🧵1/6
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Adam Braithwaite @braithwaiteat.bsky.social · 03/07/2025
Stimulating immune cells in vitro is a common experimental lab model. We profiled 150K blood immune cells treated with 11 different stimuli to compare the effects. The data are freely available for researchers. See the preprint for our findings and to access the data 🧪 doi.org/10.1101/2025...
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Rebecca Drummond 🍄 @therad-lab.bsky.social · 14/08/2025
Very excited to announce launch of brand new journal npj Fungal Science! As EIC I'm joined by a fantastic board of academic editors from across the mycology field. You can learn more about the journal scope and submit your work here: www.nature.com/npjfungalsci/
nature.com
npj Fungal Science
TBC
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 12/08/2025
Spain is on fire. Italy, Greece, Portugal — all burning. We have had summer fires before, but never like this. This is climate breakdown in real time. It is killing people, animals, and our future. DAMN the climate deniers. DAMN those who know and could do but do NOTHING www.bbc.com/news/article...
bbc.com
Wildfires rage across southern Europe as temperatures pass 40C
The heatwave has led to red alerts being issued in parts of Italy, France, Spain, Portugal and the Balkans.
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David Albesa @davidalbesa.bsky.social · 07/08/2025
📢 Job alert! The Structural Microbiology Laboratory (albesalab.org) has two new openings! We are looking for a PhD student and a Research Technician to join our team. Project: "Structure-function studies of Type VI secretion system toxins". www.biofisika.org/en/join-us Apply before 30th September
albesalab.org
Albesa Lab – Structural Microbiology Laboratory
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Neil Gow @neil-gow.bsky.social · 07/08/2025
New work from the Prasad lab showing that Candida auris can become amphotericin resistant either by multiple, sterol dependent and sterol independent mechanisms. dx.doi.org/10.1111/mmi..... @mrccmm.bsky.social @youngecmm.bsky.social @ishamycology.bsky.social @bsmm-meeting.bsky.social
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Magdalena Skipper @magdalenaskipper.bsky.social · 02/08/2025
This is fascinating - the brain fires up immune cells when sick people are nearby 🧪 www.nature.com/articles/d41...
nature.com
The brain fires up immune cells when sick people are nearby
When people viewed virtual avatars with coughs or rashes, their brains triggered an immune response.
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Institut Pasteur Education @pasteuredu.bsky.social · 01/08/2025
🖥️ The MOOC “Medical Mycology” is open for registration!    👉 bit.ly/medical-myco... 🍄 Welcome to the fascinating world of fungi, agents of major infectious diseases! Discover the taxonomy, ecology, identification of fungi, epidemiology of infectious diseases, drugs, link with HIV…Share this info!
bit.ly
Medical Mycology
Welcome to the fascinating world of fungi, agents of major infectious diseases!
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Kew Gardens @rbgkew.bsky.social · 25/07/2025
This #FungiFriday marks the opening of Kew’s new #CarbonGarden! With its big mushroom centrepiece, we thought we would dig into Fungi’s indispensable role in carbon storage; through nutrient cycling, soil formation, and as symbionts with plants 🍄🍄🟫
Carbon Garden at Kew. Featuring a structured shaped like a fungi
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David Sancho @sancholab.bsky.social · 16/07/2025
💥 A gut microbe metabolite that drives #atherosclerosis? Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol. 🧪 We show the pathway—and how to block it. nature.com/articles/s41... #OpenAccess at @Nature @CNIC_CARDIO #CVD #immunosky #cardiosky #microbiomesky
nature.com
Imidazole propionate is a driver and therapeutic target in atherosclerosis - Nature
Imidazole propionate produced by gut microbiota is associated with atherosclerosis in mouse models and in humans, and causes the development of atherosclerosis through activation of the imidazoline-1 ...
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CIC bioGUNE @cicbiogune.bsky.social · 03/07/2025
#bioGUNE_Jobs |🧬 #CICbioGUNE seeks postdocs for #MSCActions @ec.europa.eu PF 2025! Ready to boost your career in cutting-edge biomedical research? 📅 Deadline: September, 10th 📽️ Hear from our 2024 fellows in new videos youtube.com/shorts/YHGxz...
youtube.com
Historias Marie Curie - Aize Pellón Rodríguez
YouTube video by CIC bioGUNE
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Sophien Kamoun @kamounlab.bsky.social · 11/07/2025
I just published: Why I’m skipping the Congress this year (And why you should still publish your posters) Publishing your poster creates a citable record and protects you from bad actors. #ISMPMI2025 #OpenMPMI #AcademicChatter #PhDchat medium.com/p/why-im-ski...
medium.com
Why I’m skipping the Congress this year (And why you should still publish your posters)
Publishing your poster creates a verifiable and citable record of your work. It also protects you from bad actors — the evidence will be…
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CIC bioGUNE @cicbiogune.bsky.social · 22/05/2025
#bioGUNE_Outreach | #CICbioGUNE @brtaeus.bsky.social participó en @pintofscience.es #Bilbao los días 19, 20 y 21 de mayo @aizepellon.bsky.social y Edurne Berra acercaron su investigación sobre inmunidad, microbiota e hipoxia en un entorno cercano y divulgativo 🔗 ow.ly/WrUk50VWUhj
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Aize Pellón Rodríguez @aizepellon.bsky.social · 22/05/2025
El lunes tuve el placer de participar en @pintofscience.es, festival de ciencia internacional y su X edición en España, con mi charla "Amigos para recordar: memoria innata y microbiota". ¡Fue una gran experiencia! @cicbiogune.bsky.social @anguitalab.bsky.social #PINT25ES #PINT25BIO
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Mikel López Iturriaga @mikeliturriaga.bsky.social · 15/05/2025
Gentes de Bluesky, firmad esto que es importante: iniciativa ciudadana europea para prohibir las "terapias" de conversión de personas LGTBIQ+. NO es un change.org, puede suponer un cambio legal real. Y no lo dejéis para luego, que se acaba el sábado. eci.ec.europa.eu/043/public/#...
eci.ec.europa.eu
European Citizens' Initiative
Give your support !
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Aize Pellón Rodríguez @aizepellon.bsky.social · 14/05/2025
El próximo lunes 19 a las 7:00pm estaré en Hika Ateneo (Bilbo) charlando sobre la investigación realizada en nuestro laboratorio para entender la comunicación entre nuestro sistema inmunitario y la microbiota (microbios que habitan nuestro cuerpo) 👇 @pintofscience.es #PINT25BIO #PINT25ES
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Aize Pellón Rodríguez @aizepellon.bsky.social · 13/05/2025
Our review paper "Friends to remember: innate immune memory regulation by the microbiota" is now live in the May issue of Trends in Microbiology. See the link below! 👇 @anguitalab.bsky.social @cicbiogune.bsky.social @upvehu.bsky.social @cp-trendsmicrobiol.bsky.social
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Trends in Microbiology @cp-trendsmicrobiol.bsky.social · 13/05/2025
The May issue is live now! Cover image showing plasmid and phage transmission trade-offs. As part of our series on geographical inclusion, in this issue, we look at expanding microbiome sciences in the Caribbean and the need for Africa-focused microbiome initiatives. www.cell.com/issue/S0966-...
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Tom Gauld @tomgauld.bsky.social · 03/05/2025
A recent @newscientist.com cartoon #fungi
Panel One:
A scientist is giving a lecture. she stands at a lecturn. The current slide shows a list of the five kingdoms of living things: Animalia, Plantae, Fungi, Protista and Monera. She says "Most people assume that fungi are plants. Whereas in fact, they form a kingdom of their own."

Panbel Two:
Caption : After the lecture 
The scientist now appears to be in a subterranean cave, before her stand two very large mushrooms guarding a larger, beardedmushroom who sits in athrone wearing a crown. One of the mushrooms says "His majesty is very pleased with the work you are doing."
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Johan Duchêne @johanduchene.bsky.social · 30/04/2025
Antibodies don't work. NLRP3 is by far the most studied inflammasome — yet <30% of commercial antibodies were specific. Only 4 of 14 tested antibodies detected NLRP3 specifically. Antibodies must be validated before use. Full report by @ycharos.bsky.social : zenodo.org/records/1162...
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Microbial Pathogenicity Mechanisms @mpm-hki.bsky.social · 17/04/2025
Our newest review is published @nature.com Reviews Microbiology! 🥳 Together with Julian Naglik, we discuss the interplay of #Candida albicans, the host, and the microbiota during commensalism and pathogenicity. 🍄🦠 Check out the article here 👉 www.nature.com/articles/s41... @leibniz-hki.de
nature.com
Commensalism and pathogenesis of Candida albicans at the mucosal interface - Nature Reviews Microbiology
In this Review, Hube and colleagues overview the commensal and pathogenic lifestyles of Candida albicans, focusing on how the fungus transitions between these two states, the fungal and host factors i...
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Nature Reviews Microbiology @natrevmicro.nature.com · 17/04/2025
New online! Commensalism and pathogenesis of Candida albicans at the mucosal interface
nature.com
Commensalism and pathogenesis of Candida albicans at the mucosal interface
Nature Reviews Microbiology, Published online: 17 April 2025; doi:10.1038/s41579-025-01174-xIn this Review, Hube and colleagues overview the commensal and pathogenic lifestyles of Candida albicans, focusing on how the fungus transitions between these two states, the fungal and host factors involved, and the role of the mucosal microbiota on C. albicans commensalism.
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Nature @nature.com · 15/04/2025
To combat long-overlooked fungal pathogens, researchers and regulators must embrace innovative science and policy go.nature.com/4jbh96j
go.nature.com
High time to tackle drug-resistant fungal infections
To combat long-overlooked fungal pathogens, researchers and regulators must embrace innovative science and policy.
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AspGRPC @aspgrpc.bsky.social · 16/04/2025
Do you run a research lab working on Aspergillus? The Aspergillus Genomes Research Policy Committee is looking to host a list of Aspergillus labs on its webpage! Drop us a message with your lab website and a photo and we'll get it listed. Have a look here for inspiration aspgrpc.com/aspergillus-...
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