Organelle biogenesis in the rapidly growing malaria parasite requires extensive membrane genesis and remodeling. Here a mechanism to directly supply lipids from the ER to the inner membrane complex (I...

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Many antibiotics are ineffective against Gram-negative pathogens such as Pseudomonas aeruginosa because they cannot penetrate the bacterial outer membrane. Here, we show that protein antibiotics calle...

Nature Cell Biology - Wang et al. show the recruitment of the lipid channel protein VPS13C and formation of VPS13C-dependent contacts between endoplasmic reticulum and lysosomes after lysosomal...