Reposted by AgnisrotaScaffidi Lab @scaffidilab.bsky.social · 17/06/2026Last two weeks to register 021
Reposted by AgnisrotaKaushik Ragunathan @kaushikr.bsky.social · 03/08/2026Our new study shows a CHD-family remodeler can nucleate and spread H3K9 methylation de novo, inverting the canonical hierarchy between writers and remodelers. www.biorxiv.org/content/10.6...biorxiv.orgNucleosome remodeling by a CHD enzyme promotes H3K9 methylation establishment and spreading via remodeler-writer feedbackIn Schizosaccharomyces pombe , the conserved CHD remodeler Mit1 function within the SHREC remodeler-deacetylase complex (a homolog of the metazoan Mi-2/NuRD complex), which is essential for H3K9 methy... 14719
Reposted by AgnisrotaAl-Sady lab @al-sadylab.bsky.social · 27/09/2025Very proud of this story and the amazing Agnisrota Mazumder @agnisrota.bsky.social. An exciting joint journey of exploration with @thebraunlab.bsky.social in subtelomeric heterochromatin. Many surprises but, one that stuck are the unique co-existing epigenetic states in the same domain. 131
Reposted by AgnisrotaThe Braun Lab @thebraunlab.bsky.social · 27/09/2025This one feels special: our latest work on subtelomeric heterochromatin is now on www.biorxiv.org/content/10.1.... This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.biorxiv.orgDiscrete Subdomains Establish Epigenetic Diversity in Subtelomeric HeterochromatinSubtelomeres are imperfect repeats adjacent to telomeres that are repressed by heterochromatin. Although essential for genome integrity, their repetitive nature has thwarted dissection of local hetero... 32510
Reposted by AgnisrotaGesellschaft für Genetik @gfgenetik.bsky.social · 25/09/2025Amazing 2. day at the GfG ‘Epigenetics & Chromatin’ symposium. Fantastic flash talks, a great first poster session and many memorable talks: among others @erhardtlab.bsky.social, @rodvilla.bsky.social, @thebraunlab.bsky.social, @flurylab.bsky.social, Ehrenhofer-Murray, Liefke, Heun, Imhof & Brehm. 0138
Reposted by AgnisrotaGesellschaft für Genetik @gfgenetik.bsky.social · 24/09/2025What a great first day at the GfG symposium on epigenetics & chromatin. Fantastic talks by @akispapantonis.bsky.social , @apombo1.bsky.social, @marcusbuschbeck.bsky.social and Philipp Korber. And Peter Becker giving the Max-Delbrueck lecture. A real treat for the audience! 0115
Reposted by AgnisrotaThe Braun Lab @thebraunlab.bsky.social · 16/08/2025Farewell to guest student Rosario Brockhausen (Constructor Univ. Bremen) 🎉 . In just 2 months she made big strides, key manuscript contributions & was a wonderful colleague. Hope to see her back soon! 👋 051
Reposted by AgnisrotaRobin Allshire 🇮🇪 🇪🇺✊🏿 ⬆️ Zak’s favourite nucleosome: K9me @allshire-lab.bsky.social · 25/02/2025Epigenetics Gordon Research Conference. Consider joining us for what will be an excellent, exciting meeting and will be held in Europe for the first time: 10-15 Aug25 Barcelona, Spain. Please repost and apply early - this meeting is popular! www.grc.org/epigenetics-...grc.org2025 Epigenetics Conference GRCThe 2025 Gordon Research Conference on Epigenetics will be held in Castelldefels, Barcelona Spain. Apply today to reserve your spot. 13619
Reposted by AgnisrotaThe Groth lab @grothlab.bsky.social · 06/03/2025𝐍𝐞𝐰 𝐦𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐭𝐢𝐜 𝐢𝐧𝐬𝐢𝐠𝐡𝐭𝐬 𝐢𝐧𝐭𝐨 𝐭𝐡𝐞 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐡𝐢𝐬𝐭𝐨𝐧𝐞 𝐬𝐮𝐩𝐩𝐥𝐲! Excited to share our latest collaboration led by tkjeong.bsky.social and ciaranfrater.bsky.social! Structural determination of the histone chaperone ASF1 and its regulator CODANIN-1 uncovers how CODANIN-1 counters ASF1 activity. 🧵👇rdcu.beCODANIN-1 sequesters ASF1 by using a histone H3 mimic helix to regulate the histone supplyNature Communications - CODANIN-1 negatively regulates the function of ASF1, the key chaperone for histone H3-H4 supply. Here the authors present the cryo-EM structure of the CODANIN-1_ASF1A... 15514
Reposted by AgnisrotaMarty Yang @martyyang.bsky.social · 15/11/2024Excited to share the first story from my post-doc, co-led with Megan Ostrowski! Many thanks to @vram142.bsky.social and all our wonderful co-authors and collaborators for making this project a huge success: www.cell.com/cell/fulltex...cell.comThe single-molecule accessibility landscape of newly replicated mammalian chromatinBy developing a long-read sequencing method to simultaneously map replication status and protein-DNA contacts in cells, Ostrowski, Yang, et al. show that newly replicated chromatin is enriched for unw... 1256
Reposted by AgnisrotaCRC 1064 Chromatin Dynamics @crc1064.bsky.social · 25/03/2025#ChromatinDays – Join Us! SFB 1064's final annual meeting! Talks, reunion & BBQ Bash 🍖 on May 26-27. Guest speakers: former SFB & IRTG members. Alumni, don’t miss the BBQ & IRTG Satellite Session! 📢 Register now! Scan the QR code or visit: www.sfb1064.med.uni-muenchen.de/chromatin-da... 🐝 there! 086