iiinova — where your digital self keeps evolving

Reposted by Al-Sady lab

Abby Buchwalter @abbybuch.bsky.social · 24/09/2026

It has been a pleasure to watch @jmella.bsky.social lead this project - a technical tour de force that brought saturation mutagenesis to cardiomyocytes for the first time, revealed CM-specific effects of LMNA mutations + new features of lamin structure and quality control.

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Mark Pownall @mpownall.bsky.social · 17/08/2026

First preprint from the lab 🚨 We asked when and how global chromatin organization emerges during early development 🐟

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Reposted by Al-Sady lab

Noam Ross @noamross.net · 21/08/2026

Three more days to comment on NSF's attempt to smuggle in OMB's already-rejected policies of terminating any grant without cause, gutting civil rights obligations and restricting international collaborations. Submit your comment today! Then call your representatives. 🧪

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Al-Sady lab @al-sadylab.bsky.social · 10/08/2026

So.. Odyssey… made a whole day out of it, spent the afternoon in Japantown, and saw it late in 70mm at the Kabuki. It was… very mid. Under expectation. Takes itself way too seriously.

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Al-Sady lab @al-sadylab.bsky.social · 23/07/2026

Genuinely - I don’t know what we can do anymore. I mean universities esp medical ones like mine have to completely rethink their model to keep science going, till some change down the line. Yes it’s “up to Congress” - but this will have a big impact. Evident already. www.nytimes.com/2026/07/22/u...

nytimes.com

Trump’s Plan for Science: More Money for A.I., Less for Universities

Michael Kratsios, President Trump’s science adviser, proposed overhauling how the government funds research. Democrats said Mr. Trump’s actions had weakened science.

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Al-Sady lab @al-sadylab.bsky.social · 21/07/2026

UEFAs dominance has become striking. Overall WC balance stands 10-13 CONMEBOL- UEFA, but UEFA got 70% of the last 10. CONMEBOLs teams really didn’t impress this year and much work needs to be done. Football isn’t football without South America.

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Al-Sady lab @al-sadylab.bsky.social · 20/07/2026

I get the whole CONMEBOL mentality, we fight for it, even with "dark arts" ok, but 100min without a shot from the Champions is sad, cynical, and reminds me of the 1990 Final- which I watched- same story. Maybe without an aged superstar savior, the team can rebuild into something more positive.

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Al-Sady lab @al-sadylab.bsky.social · 19/07/2026

Correct team wins. Finally in the last match, it works out.

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Al-Sady lab @al-sadylab.bsky.social · 19/07/2026

In Paris. Seeing only Argentina jerseys- what’s up! Where are all the Furia Roja supporters? Go Spain!!!🇪🇸

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Al-Sady lab @al-sadylab.bsky.social · 15/07/2026

Those were the Lex Luthor WC semis. Kryptonite won out on both sides.

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Al-Sady lab @al-sadylab.bsky.social · 15/07/2026

And… I was wrong. The spell of England being unable to beat any of the current World Cup holders since 66 (or runners up) will go past 60 years. Amazing. Admittedly Tuchels tactics were horrendous after scoring- you can’t just defend against Argentina for 45 min. And take off most of the attack.

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Al-Sady lab @al-sadylab.bsky.social · 14/07/2026

Seen teams after teams I support crash out off this WC and I am the stage of really not caring who wins for the first time, just mildly hoping Argentina doesn’t win. Sad.

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Al-Sady lab @al-sadylab.bsky.social · 13/07/2026

Prediction - England on 7/15 will do what they failed to do since ‘66: beat any World Cup trophy holder in a KO WC game. Argentina 🇦🇷 hasn’t been at all convincing against mid and low level sides, and should probably have lost to 🇪🇬. Real doubts they can stand up to 🏴󠁧󠁢󠁥󠁮󠁧󠁿 physicality esp on their right.

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Al-Sady lab @al-sadylab.bsky.social · 12/07/2026

FIFA ensures the most boring but very marketable semifinals

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Al-Sady lab @al-sadylab.bsky.social · 11/07/2026

Alright Haaland, 🇳🇴 . Let’s do this.

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Al-Sady lab @al-sadylab.bsky.social · 10/07/2026

World Cup is entering the boring phase. Come on Norway come on Belgium keep it interesting!

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Al-Sady lab @al-sadylab.bsky.social · 07/07/2026

All the countries I supported are crashing out! Hopes pinned to Morocco now.

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Al-Sady lab @al-sadylab.bsky.social · 07/07/2026

So Argentina conceded twice against Capo Verde and three times against Egypt. They won’t survive the Semi final. England or Norway will eat them. HUGE kudos to Mo Salah and Egypt. What an inspired performance and what a great World Cup for them. See you next time!!

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Al-Sady lab @al-sadylab.bsky.social · 07/07/2026

Completely unacceptable VAR decision against Egypt

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Al-Sady lab @al-sadylab.bsky.social · 05/07/2026

Not the way to go out coach Marsh. Just because Morocco 🇲🇦 underperformed, badly, one half, doesn’t make you the better team. You lost 0-3 without a controversial call. Do better Canada 🇨🇦 - sportsmanship.

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Al-Sady lab @al-sadylab.bsky.social · 05/07/2026

I am all for underdogs but anti football teams have to go. Paraguay- Ghana- not impressed. Underdogs for the heart- Cape Verde 🇨🇻, 🇪🇬 led but an amazing person in Mo Salah, DR Congo, amazing, even the USA so far much above prior level, etc etc.

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Al-Sady lab @al-sadylab.bsky.social · 04/07/2026

So here is 🏴󠁧󠁢󠁥󠁮󠁧󠁿 ‘s challenge: it’s not “bringing it home” or merely surviving the Azteca. I was researching this and it’s crazy: since ‘66 🏴󠁧󠁢󠁥󠁮󠁧󠁿 has NEVER beaten a current WC holder or even runner up in a KO game. That’s remarkable. That’s what they have to do get back in it. 60 years it has eluded them.

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Al-Sady lab @al-sadylab.bsky.social · 04/07/2026

Whatever happens next seeing this is crazy. The will be heroes to be remembered in their country forever.

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Al-Sady lab @al-sadylab.bsky.social · 01/07/2026

Congo !!!!!! Whatever happens leading England into the Half like that - amazing. Just amazing.

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Al-Sady lab @al-sadylab.bsky.social · 30/06/2026

How was that a 5-4 decision ???

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Al-Sady lab @al-sadylab.bsky.social · 30/06/2026

Knocked out at Round of 32 is the same really as same the old group stage exit. No improvement from Germany in 3 WC. Sad.

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Al-Sady lab @al-sadylab.bsky.social · 22/06/2026

Never liked Argentinean football. Its cynical and largely reliant on one Uber gifted talent. I swear. Has nothing to do with being German.

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Al-Sady lab @al-sadylab.bsky.social · 17/06/2026

Just LOVING Croatia’s 🇭🇷 comebacks

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Al-Sady lab @al-sadylab.bsky.social · 17/06/2026

Klose’s record sadly to fall shortly …

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Al-Sady lab @al-sadylab.bsky.social · 11/06/2026

The World Cup. Starts. Tomorrow.

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Al-Sady lab @al-sadylab.bsky.social · 09/06/2026

World Cup fever despite the depressing atmospherics. As a German 🇩🇪 wish the team the best- though I feel we won’t go too deep. Interesting 🏴󠁧󠁢󠁥󠁮󠁧󠁿 stat I just realized : 🏴󠁧󠁢󠁥󠁮󠁧󠁿 since 1966 has never beaten any of the current 8 🏆holders in a knockout game! Maybe with a German coach they can do it! Good luck 🏴󠁧󠁢󠁥󠁮󠁧󠁿.

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Al-Sady lab @al-sadylab.bsky.social · 12/05/2026

We keep having had fun with our workshops. PhD candidate Can Goksal gave a great introductory one to IDR biology- follow ups to come! Our workshops are all online here alsadylab.ucsf.edu/resources

alsadylab.ucsf.edu

Resources | Al-Sady Lab

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Al-Sady lab @al-sadylab.bsky.social · 07/04/2026

Plate orders @idtdna.bsky.social are massively delayed (over a week?)- should have ordered them in tubes … IDT do better. It’s just 24 primers.

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Reposted by Al-Sady lab

Michael Borg @borglab.bsky.social · 02/04/2026

Our work on chromatin evolution in brown algae is now published in @natecoevo.nature.com! We show that developmentally complex brown algae evolved without epigenetic silencing pathways long thought universal, underscoring why non-model lineages are important to study. www.nature.com/articles/s41...

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Al-Sady lab @al-sadylab.bsky.social · 06/03/2026

Bay Area Chromatin Club today at UCSF Mission Bay. Great mechanistic talks from UCSF, Berkeley, Stanford, UCSC, and Genentech. High attendance, awesome posters, many great questions and interactions. (Photo credit to Active Motif, who generously support this awesome series). See you at the next one!

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Reposted by Al-Sady lab

Mia Levine @levine-lab.bsky.social · 23/02/2026

Cara will continue her work on coevolution between DNA satellites and essential host proteins in her new lab in the Dept of Genetics at Rutgers! See: genetics.rutgers.edu/people/facul...

genetics.rutgers.edu

Cara Brand

Department of Genetics at Rutgers University

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Al-Sady lab @al-sadylab.bsky.social · 22/02/2026

Our full BACC lineup of speakers is up! Looks to be a fun program with talks from UCSC, Berkeley, Stanford, UCSF, and Genentech. Take a peek- still slots available to register and present a poster. March 5, 1-5pm www.eventbrite.com/e/bay-area-c...

eventbrite.com

Bay Area Chromatin Club - In Person Symposium: March 5, 2026

The Chromatin Club Bay Area was founded to foster a scientific community between academic and industry members in and around the Bay Area.

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Al-Sady lab @al-sadylab.bsky.social · 21/02/2026

Fun as ever at amazing w-qBIO! This year the kids that grew up in this meeting kicked it off and introduced some plenary speakers. A wonderful tradition and great science. Here organizers that got us going- @hanascientist.bsky.social and Wendell Lim. The work I presented was Entirely qBIO inspired.

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Al-Sady lab @al-sadylab.bsky.social · 16/02/2026

Register for the Bay Area Chromatin Club in 2026! It’s free. March 5, 1-5pm Genentech Hall. We have speakers from UCSF, Stanford, Cal, and more ! It’s a great event for trainees to discuss their work and get feedback- bring a poster ! Hang with old and new friends. urldefense.com/v3/__https:/...

urldefense.com

Bay Area Chromatin Club - In Person Symposium: March 5, 2026

The Chromatin Club Bay Area was founded to foster a scientific community between academic and industry members in and around the Bay Area.

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Al-Sady lab @al-sadylab.bsky.social · 15/02/2026

Happy Valentine’s Day! My 12 yr old son got this rose on Jan 22nd for doing a talk in his schools TedX youth event. The rose is still alive after! He says as long as it’s alive he’ll remember his talk. It was really a fun experience, starting August with research, Oct-Dec writing, and talk prep. 1/2

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