Sign in

acasadevall1.bsky.social

@acasadevall1.bsky.social
834 followers 37 following 23 posts
PostsRepliesMedia
acasadevall1.bsky.social @acasadevall1.bsky.social · 24/08/2026
'And plasma treatments proved effective, bringing the fatality rate from as high as 30 percent down to 1 percent for patients who received prompt care. Outbreaks dwindled'...a plug for convalescent plasma. www.nytimes.com/2026/08/21/w...
nytimes.com
Rare South American Diseases Offer Clues on the Next Pandemic
Ebola virus, hantavirus and the pathogen that causes Covid-19 likely jumped from animals to humans. So do these viruses — and scientists say climate change is speeding their spread.
030
acasadevall1.bsky.social @acasadevall1.bsky.social · 21/08/2026
www.techtimes.com/articles/323...
techtimes.com
Candida auris Hides in Hair Follicles by Rewiring Skin Immunity, Science Study Finds
Candida auris permanently colonizes patients by using chitin to trigger a skin immune response that suppresses antifungal defenses, allowing it to hide in hair follicles no current treatment can reach...
031
acasadevall1.bsky.social @acasadevall1.bsky.social · 11/08/2026
My fun and free ranging conversation with @sdesmon.bsky.social on fungal blooms in the cretaceous, mammalian evolution, climate change and fungal diseases podcast. podcast.publichealth.jhu.edu/are-humans-h...
052
Reposted by @acasadevall1.bsky.social
Public Health On Call Podcast @publichealthpod.bsky.social · 10/08/2026
Discovery of massive fungal blooms in the Cretaceous period suggest significant ecological upheaval before and after the asteroid wiped out the dinosaurs. @acasadevall1.bsky.social explains the significance of these findings. 🎧 podcast.publichealth.jhu.edu/are-humans-h...
Promo graphic for episode 1089 of Public Health On Call titled Are Humans Hot Enough to Survive a Fungal Apocalypse? Additional text reads: Fungi may have guided human evolution. How could it shape our future?
011
Reposted by @acasadevall1.bsky.social
Nichole Broderick, PhD @nabroderick.bsky.social · 06/08/2026
Final call for abstracts! 8th Conference on Model Hosts, Oct 3-8th Sissi Crete. Thanks to support from @microbiologysociety.org and @femsmicro.org we have funding for a number of trainee travel awards - submit your abstract and apply today! aegeanconferences.org/conferences/...
Image of an Aegean coastal town advertising a scientific conference on model hosts.
179
acasadevall1.bsky.social @acasadevall1.bsky.social · 03/08/2026
www.livescience.com/animals/dino...
livescience.com
Did fungi give mammals an evolutionary edge after the dinosaur-killing asteroid hit? New evidence revives a provocative hypothesis
A revived hypothesis argues that a fungus-filled world after the Chicxulub asteroid impact may have given mammals an evolutionary edge. The idea could reshape how scientists think about mass extinctio...
011
acasadevall1.bsky.social @acasadevall1.bsky.social · 17/06/2026
Fungi produce volatile compounds that attract insects. Benefit for fungi may be spore dispersal. Attraction signature suggests new opportunities for designing mosquito traps. publichealth.jhu.edu/2026/beyond-...
publichealth.jhu.edu
Beyond Bread and Beer: Alluring Yeast Species Could Yield New Mosquito Traps to Combat Malaria | Johns Hopkins Bloomberg School of Public Health
New study details common yeast’s surprising ability to attract mosquitoes with its fragrance and sticky quality.
021
acasadevall1.bsky.social @acasadevall1.bsky.social · 13/06/2026
What is missing in all these discussions is the fact that Ebola convalescent plasma is already potentially available and could provide a therapeutic bridge to the time when antivirals, vaccines, monoclonals are available. See this OpED thehill.com/opinion/heal...
thehill.com
Power of plasma: How to curb new viral outbreaks that lack vaccines
When people recover from viral diseases, they make antibodies that can then be transferred to other affected individuals. Enter convalescent plasma.
000
Reposted by @acasadevall1.bsky.social
Dept of Molecular Microbiology & Immunology at Johns Hopkins @johnshopkinsmmi.bsky.social · 01/06/2026
What fungi can tell you about a dying ecosystem A new study by @johnshopkinssph.bsky.social @jhu.edu @jhu-bdps.bsky.social @acasadevall1.bsky.social and Rosanna Baker in @pnas.org reports a finding that complicates the standard version of the dinosaur extinction. spacedaily.com/d-the-astero...
spacedaily.com
The asteroid that wiped out the dinosaurs may have struck a planet that was already in serious trouble — a new Johns Hopkins study has found evidence of a separate ecological crisis that began about 3...
A study published in May 2026 in the Proceedings of the National Academy of Sciences reports a finding that complicates the standard one-line version of the dinosaur extinction. Two researchers at the...
021
Reposted by @acasadevall1.bsky.social
Dept of Molecular Microbiology & Immunology at Johns Hopkins @johnshopkinsmmi.bsky.social · 09/06/2026
In this @thehill.com piece @johnshopkinssph.bsky.social @jhu.edu @jhu-bdps.bsky.social @acasadevall1.bsky.social explores convalescent plasma as a possible therapy for recent outbreaks hantavirus and Ebola, and for other public health threats. thehill.com/opinion/heal...
thehill.com
Power of plasma: How to curb new viral outbreaks that lack vaccines
When people recover from viral diseases, they make antibodies that can then be transferred to other affected individuals. Enter convalescent plasma.
075
acasadevall1.bsky.social @acasadevall1.bsky.social · 08/06/2026
As we face new viral outbreaks there is a potentially available therapy already available in the plasma of survivors. The experience with convalescent plasma during COVID-19 can inform dealing with outbreaks of Ebola, hantavirus and whatever else will come. thehill.com/opinion/heal...
thehill.com
Power of plasma: How to curb new viral outbreaks that lack vaccines
When people recover from viral diseases, they make antibodies that can then be transferred to other affected individuals. Enter convalescent plasma.
041
acasadevall1.bsky.social @acasadevall1.bsky.social · 28/05/2026
publichealth.jhu.edu/2026/fungal-...
publichealth.jhu.edu
Fungal Surges Marked Cretaceous Mass Extinction that Ended Age of Dinosaurs | Johns Hopkins Bloomberg School of Public Health
New findings highlight fungal microfossils as useful markers in paleontological research.
022
Reposted by @acasadevall1.bsky.social
Nichole Broderick, PhD @nabroderick.bsky.social · 20/03/2026
Excited to announce our new journal from @isme-microbes.bsky.social ISME Host Microbe is live and now accepting submissions. Look forward to receiving your papers! #Microsky 🧫 🦠
Image of the cover of the 1st volume of ISME Host Microbe a new official journal of the International Society for Microbial Ecology. Cover images shows a plant stomata with bacteria around and entering.
312587
acasadevall1.bsky.social @acasadevall1.bsky.social · 13/05/2026
Is SARS-CoV-2 teratogenic? In this editorial we argue that although risk in pregnancy is low, there are enough observations to raise cautious concerns. This question needs more study given that the virus is now endemic. pubmed.ncbi.nlm.nih.gov/42096206/
000
acasadevall1.bsky.social @acasadevall1.bsky.social · 13/05/2026
Visiting @symbionticism.bsky.social and was greeted with starburst candy thanks to @markowenmartin.bsky.social who told him about using these to collect fungi from Baltimore sidewalks. All credit goes to highly innovative Daniel Smith who thought of this - see pubmed.ncbi.nlm.nih.gov/41142051/
141
acasadevall1.bsky.social @acasadevall1.bsky.social · 12/09/2025
Research inspired by melanin studies with C. neoformans suggests new approach to mosquito control for malaria. publichealth.jhu.edu/malaria-rese...
publichealth.jhu.edu
The Goldilocks Dose: Modulating Mosquito Diet to Control Malaria | Johns Hopkins Malaria Research Institute
Feeding mosquitoes L-DOPA can either strengthen their defences against malaria or shorten their lifespan — showing that in vector control, the dose makes the difference
020
Reposted by @acasadevall1.bsky.social
CMI Communications @cmicomms.bsky.social · 13/07/2025
🎙️ Just published a new #Communicable episode: Communicab... Hosted by Angela Huttner @angelahuttner.bsky.social Josh Nosanchuk @josh-nosanchuk.bsky.social with invited guest: Arturo Casadevall @acasadevall1.bsky.social (Johns Hopkins University) Listen here: #IDSky #Clinmicro #MedSky
share.transistor.fm
Communicable E31: Climate change and fungal spread
The adaptability of fungi to warmer temperatures is an obvious...
2148
Reposted by @acasadevall1.bsky.social
CMI Communications @cmicomms.bsky.social · 10/07/2025
📣 Next #Communicable drops Mon 14 July! @angelahuttner.bsky.social & @josh-nosanchuk.bsky.social invite Arturo Casadevall @acasadevall1.bsky.social (Johns Hopkins) to discuss the spread of #fungi due to climate change, and what that means for fungal pathogenesis & infection #IDSky #clinmicro #MedSky
0188
acasadevall1.bsky.social @acasadevall1.bsky.social · 10/07/2025
Quoted here about the increasing problem of drug resistance in Aspergillus isolates. www.nbcnews.com/health/healt...
nbcnews.com
Fungal infections are getting harder to treat
The fungus Aspergillus fumigatus tops the World Health Organization's list of worrying fungal diseases. It's growing increasingly resistant to the first-line drug used to treat it.
095
Reposted by @acasadevall1.bsky.social
PLOS Biology @plosbiology.org · 16/05/2025
To what extent can we predict future pathogenic #microbes? @acasadevall1.bsky.social discusses why probabilistic predictions are difficult, but not impossible. 🧪 plos.io/3EXieQp
plos.io
Is pathogen prediction possible?
To what extent can we predict future pathogenic microbes? This Perspective discusses why complex requirements for virulence and dynamic host-microbe interactions make probabilistic predictions difficu...
01912
Reposted by @acasadevall1.bsky.social
Dept of Molecular Microbiology & Immunology at Johns Hopkins @johnshopkinsmmi.bsky.social · 28/05/2025
CAN WE STOP KILLER FUNGI? Fungal diseases are more common, more dangerous & more difficult to treat. This fascinating BBC podcast features 4 global #fungi experts including @johnshopkinssph.bsky.social @jhu.edu @acasadevall1.bsky.social - interview at 10:55 time marker www.bbc.co.uk/sounds/play/...
bbc.co.uk
The Inquiry - Can we stop killer fungi? - BBC Sounds
Why fungal diseases are becoming more dangerous to human health
021
Reposted by @acasadevall1.bsky.social
Carl Zimmer @carlzimmer.com · 28/05/2025
The Last of Us may be over for now, but fungus pandemic news endures. Here's my story on how white-nose disease, which has battered North American bats, may have more devastation in store. 🧪 Gift link: nyti.ms/4mGRyV8
nyti.ms
A Fungus Devastated North American Bats. A New Species Could Deliver a Killer Blow. (Gift Article)
Scientists have learned that another species of fungus found in Europe and Asia causes white-nose disease, which has ravaged bat populations in the United States and Canada.
14932
Reposted by @acasadevall1.bsky.social
Waggoner Lab @labwaggoner.bsky.social · 21/03/2025
Review @natrevimmunol.bsky.social @acasadevall1.bsky.social New insights into antibody structure with implications for specificity, variable region restriction and isotype choice www.nature.com/articles/s41...
nature.com
New insights into antibody structure with implications for specificity, variable region restriction and isotype choice - Nature Reviews Immunology
Immunoglobulins sample vast swathes of primary sequence and conformational space to generate and select B cell clones with exquisite selectivity and affinity for specific antigens. This Perspective ar...
0154
Reposted by @acasadevall1.bsky.social
Jason Stajich @hyphaltip.bsky.social · 10/05/2025
share.transistor.fm/s/ee922716 - nice interview with Joe Heitman on Fungi
share.transistor.fm
Cosmic Radio Interview with Dr. Joseph Heitman: Professor and Chair of Molecular Genetics and Professor in Medicine at Duke University and CIFAR's Co-Director for the Fungal Kingdom: Threats & Opportu...
Join me on Cosmic Radio as we speak with Dr. Joseph Heitman. Dr. Heitman is a professor and Chair of Molecular Biology and Professor in Medicine at Duke University and CIFAR's Co-Director for the "Fun...
0137
Reposted by @acasadevall1.bsky.social
Dept of Molecular Microbiology & Immunology at Johns Hopkins @johnshopkinsmmi.bsky.social · 01/05/2025
A tribute to @johnshopkinssph.bsky.social Professor Diane Griffin, MD, PhD, noted virologist, former @johnshopkinsmmi.bsky.social dept chair, written by @acasadevall1.bsky.social & J. Marie Hardwick, published in @pnas.org @jhu.edu @hopkinsmedicine.bsky.social www.pnas.org/doi/10.1073/...
pnas.org
Diane E. Griffin, physician–scientist extraordinaire | PNAS
In October 2024, the scientific world lost Diane E. Griffin, a highly accomplished physician–scientist who greatly heightened our understanding of ...
0123
Reposted by @acasadevall1.bsky.social
netec.bsky.social @netec.org · 11/04/2025
🧟‍♂️ #TheLastOfUs S2 drops April 13—brush up on the science behind the spores with this throwback. 🎧 In #NETEC’s #FungalPathogens podcast episode, Dr. Arturo Casadevall (@acasadevall1.bsky.social) breaks down the fungal fact vs. fiction behind the show. Listen now:
netec.org
Pathogens in Pop Culture: Fungal Pathogens and The Last of Us
Could a fungus cause the next pandemic? Separating myth from reality; examining the science behind fungal pathogens.
011
Reposted by @acasadevall1.bsky.social
Nature Reviews Immunology @natrevimmunol.nature.com · 20/03/2025
New Perspective article from Scott McConnell & @acasadevall1.bsky.social @johnshopkinssph.bsky.social highlights the importance of constant regions in influencing the specificity and functionality of #antibodies #immunology #immunosky
nature.com
New insights into antibody structure with implications for specificity, variable region restriction and isotype choice - Nature Reviews Immunology
Immunoglobulins sample vast swathes of primary sequence and conformational space to generate and select B cell clones with exquisite selectivity and affinity for specific antigens. This Perspective article examines the interplay between antibody diversification mechanisms and highlights the importance of constant regions in influencing the specificity and functionality of individual antibodies.
0194
acasadevall1.bsky.social @acasadevall1.bsky.social · 14/03/2025
I don't understand why articles like this one never mention that we have an option for preventing disease: measles gamma globulin has a 100% efficacy in preventing disease in exposed vulnerable children. See this reference: pubmed.ncbi.nlm.nih.gov/29028959/. www.nytimes.com/2025/03/14/w...
nytimes.com
Parents of Babies Who Are Too Young for Measles Vaccine Worry About Outbreaks
Infants are at higher risk of complications from the measles but can’t be vaccinated right away.
000
Reposted by @acasadevall1.bsky.social
Mark O. Martin @markowenmartin.bsky.social · 13/03/2025
It's Thursday: time for #MattersMicrobial Episode #82! Dr. Arturo Casadevall talks with the #QualityQuorum about how fungi can use melanin to collect energy from light (and radiation), and adaptation to high temperatures. Please spread the #GoodMicrobialWord! youtu.be/D7uzJzglC40?...
161
Reposted by @acasadevall1.bsky.social
STCmicrobeblog @stcmicrobeblog.bsky.social · 13/03/2025
check #MattersMicrobial #82 👇 ...and as "supplementary material" > schaechter.asmblog.org/schaechter/2... #FungiFriends
schaechter.asmblog.org
Kool & The Gang − Celebration
by Christoph — Other than the title Kool & The Gang − Cele­bra­tion sug­gests, this post is not about the R&B band of past glories and their big­gest hit, but in­stead ce­le­brates the true "cool kids...
071
Reposted by @acasadevall1.bsky.social
Mark O. Martin @markowenmartin.bsky.social · 06/03/2025
Today's podcast recording session for #MattersMicrobial was with the amazing Dr. Arturo Casadevall. He has such interesting ideas, and I cannot wait to share them with you.
082
acasadevall1.bsky.social @acasadevall1.bsky.social · 01/03/2025
The pandemic crisis may be over, but SARS-CoV-2 remains a major problem for the immunocompromised that do not make good antibody responses. European RCT confirms efficacy of COVID-19 convalescent plasma (CCP) in this population. CCP is FDA licensed in US
120
acasadevall1.bsky.social @acasadevall1.bsky.social · 01/03/2025
As physicians confront the widening measles outbreak it is important to keep in mind that we have a highly effective means of protecting those exposed - hyperimmune IgG. It showed 100% efficacy in the 2013 NYC outbreak.
030
Reposted by @acasadevall1.bsky.social
Waggoner Lab @labwaggoner.bsky.social · 27/02/2025
A call for the United States to continue investing in science journals.asm.org/doi/10.1128/... @acasadevall1.bsky.social @bladerlab.bsky.social @goodrumviruslab.bsky.social Highlights of U.S. government-funded advances in biomedical sciences/healthcare:
133
acasadevall1.bsky.social @acasadevall1.bsky.social · 22/02/2025
As we enter another week of crisis in the biomedical sciences, I thought I would make a list of the advances in field of infectious diseases THAT I HAVE WITNESSED since I became board certified in 1990. I am sure I missed a few advances, and this is only in the field of ID.
053
acasadevall1.bsky.social @acasadevall1.bsky.social · 22/02/2025
Five years after it became the first emergency therapy for COVID-19 convalescent plasma is FDA licensed, effective, safe and relatively inexpensive since it is a donated product and keeps up with the variants. hub.jhu.edu/2025/02/03/i...
hub.jhu.edu
Convalescent plasma offers a 'blueprint' for future pandemics
Hopkins researchers help secure full FDA approval to treat immunocompromised COVID-19 patients—paving the way to explore using convalescent plasma during future infectious disease outbreaks
000
Reposted by @acasadevall1.bsky.social
JHU Bloomberg Distinguished Professorships @jhu-bdps.bsky.social · 19/02/2025
JHU has established a planning committee for immunology. The committee will be co-chaired by two Bloomberg Distinguished Professors, @acasadevall1.bsky.social and Erika Pearce, and BDP Nicole Baumgarth will be a member of the committee. hub.jhu.edu/2025/02/11/n...
hub.jhu.edu
Committee imagines a new future for immunology research at Johns Hopkins
10-member committee aims to create a groundbreaking, interdivisional organizing structure for immunology at Hopkins
032
Reposted by @acasadevall1.bsky.social
Felipe H Santiago-Tirado @felipehst.bsky.social · 10/02/2025
Hey #fungal people - the applications for this years MOMY course are open! Wonderful course in a wonderful place with wonderful people. Check it out here: www.mbl.edu/education/ad...
066
acasadevall1.bsky.social @acasadevall1.bsky.social · 06/02/2025
Warmer climates could supercharge fungal diseases transmitted by insects. pubmed.ncbi.nlm.nih.gov/39907444/
063
Reposted by @acasadevall1.bsky.social
🇨🇷 Rolando Ulloa-Gutierrez @rolandoug.bsky.social · 01/02/2025
If you're a pediatrician you should read this nice recent paper by @acasadevall1.bsky.social et al about the discovery of #RSV, the history and scientists behind it, and go back to those years. We've reached recently amazing advances in prevention. #medsky #idsky #pedssky doi.org/10.1128/mbio...
doi.org
The Story behind the Science: On the discovery of respiratory syncytial virus | mBio
Today, respiratory syncytial virus (RSV) is the leading cause of infant hospitalizations (1) and a significant cause of morbidity and mortality among older individuals (2). On 3 May 2024, the Johns Ho...
152
Reposted by @acasadevall1.bsky.social
JHU Bloomberg Distinguished Professorships @jhu-bdps.bsky.social · 08/01/2025
Gain-of-function research could enable health officials to recognize H5N1 bird flu mutations and identify targets for antivirals and vaccines. BDP @acasadevall1.bsky.social offers insights on the value of such research. www.latimes.com/environment/...
latimes.com
Why scientists say we are fighting H5N1 bird flu with one hand tied behind our backs
When, where and how the H5N1 bird flu virus may evolve and its capacity to spark a pandemic is hard to predict — in part, some researchers say, because of federal restrictions on gain-of-function rese...
021
acasadevall1.bsky.social @acasadevall1.bsky.social · 16/01/2025
Not a great picture since the window was cloudy from de-icing fluid. I am always impressed by the beauty of a sunset from a plane. Scenes like this take me back to my PhD qualifying exam where the first two questions were: why is the sky blue and the sunset red. I passed.
030
acasadevall1.bsky.social @acasadevall1.bsky.social · 13/01/2025
As of today, high titer certified COVID-19 Convalescent Plasma is available in the USA from an @US_FDA licensed supplier. To physicians out there - here is the way to order it for your patients. www.oneblood.org/pages/high-t...
oneblood.org
COVID-19 Convalescent Plasma | Learn MoreMobile
High Titer COVID-19 Convalescent Plasma is now available to order through OneBlood.
011
acasadevall1.bsky.social @acasadevall1.bsky.social · 27/12/2024
If H5N1 outbreak occurs convalescent plasma will be used again. For most efficacy: 1) identify sites for outpatient infusion; effectiness = early use; 2) get IRB paperwork done; 3) Use high titer units. www.statnews.com/2024/12/26/h...
statnews.com
Prepare now to use convalescent plasma for the next pandemic
Whether the next pandemic is caused by H5N1 bird flu or something else, we must prepare now to use convalescent plasma to treat patients.
011
acasadevall1.bsky.social @acasadevall1.bsky.social · 23/11/2024
Monoclonal antibodies (mAb) for prevention of COVID-19 progression can affect subsequent infection/vaccination. Phenomenon was not seen with convalescent plasma and may reflect large IgG dose associated with mAb therapy. pubmed.ncbi.nlm.nih.gov/39504352/
000
acasadevall1.bsky.social @acasadevall1.bsky.social · 19/10/2024
I just joined blue sky where I will continue to write about science and medicine.
1163