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Coscia Lab

@coscialab.bsky.social
240 followers 79 following 11 posts

...we are passionate about spatial proteomics, mass spectrometry and single-cell technologies to study disease mechanisms @MDC_Berlin 🇩🇪🇨🇴🇨🇳🇰🇿🇵🇷🇵🇱🇲🇽

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Reposted by Coscia Lab
MS Proteomics @mspcf.bsky.social · 19/05/2026
(2/3) Highlights for today: 1️⃣ Welcome by Dra. Marta Vilaseca (@irbbarcelona.org). 2️⃣ Insights on scaling and democratizing spatial tissue proteomics with Dr. Fabian Coscia (@coscialab.bsky.social MDC Berlin, @mdc-berlin.bsky.social). 3️⃣ Pedro Cano (Bruker @brukerspatial.bsky.social).
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Coscia Lab @coscialab.bsky.social · 17/04/2026
Unique opportunity!! :-)
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Coscia Lab @coscialab.bsky.social · 13/04/2026
Excited to share our new @natcomms.nature.com study with the @garyrlewin.bsky.social lab and @amapruns.bsky.social. Using deep visual proteomics, we created the first neuronal subset-resolved proteomic map of sensory neurons with potential implications for pain treatment. go.nature.com/481nr4R
go.nature.com
Deep visual proteomics uncovers nociceptor diversity and pain targets - Nature Communications
Sensory neuron subtypes are defined by transcriptomics, but their proteomic identities remain unclear. Here, authors show distinct protein signatures of electrophysiologically defined nociceptors and ...
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Coscia Lab @coscialab.bsky.social · 22/09/2025
Check out our latest preprint in collaboration with the @garyrlewin.bsky.social lab! We obtained the first subset-specific proteomes of pain sensing neurons!
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Coscia Lab @coscialab.bsky.social · 17/07/2025
Excited to introduce openDVP — an open-source framework to bring deep visual proteomics to the broader research community! It includes: – A simplified fast-track pipeline for easy adoption – An AI-powered option for advanced image & spatial analysis 👉 BioRxiv: bit.ly/44SBuHu 👉 Github: bit.ly/4eR3IqK
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Coscia Lab @coscialab.bsky.social · 05/06/2025
Thrilled to share our latest preprint describing an optimized spatial tissue proteomics workflow for the preparation and analysis of >100 proteomes / day at high spatial resolution. Kudos to @melissaklingeberg.bsky.social 🥳 and big thanks to all our collaborators! bit.ly/3SCARw4
bit.ly
An ultrasensitive spatial tissue proteomics workflow exceeding 100 proteomes per day
Achieving high-resolution spatial tissue proteomes requires careful balancing and integration of optimized sample processing, chromatography, and MS acquisition. Here, we present an advanced cellenONE...
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Coscia Lab @coscialab.bsky.social · 20/03/2025
Our lab's newest preprint is out on deep spatial proteomics of ovarian cancer precursor lesions! We demonstrate how ultrasensitive discovery proteomics can shed light onto early carcinogenesis, uncover cell-of-origin signatures, and prioritize novel drug targets. bit.ly/41M7fke
biorxiv.org
Deep spatial proteomics of ovarian cancer precursor lesions delineates early disease changes and cell-of-origin signatures
High-grade serous ovarian cancer (HGSOC) is a devastating disease that is frequently detected at an advanced and incurable stage. Advances in ultrasensitive mass spectrometry-based spatial proteomics ...
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Reposted by Coscia Lab
Shabaz Lab @shabazlab.bsky.social · 07/03/2025
Shout out to the organisers @jesperolsenlab.bsky.social, (Tina Ludwig) @baybioms.bsky.social kathrynslilley.bsky.social, Caroline May and Britta Eggers and the speakers @bonalditiziana.bsky.social, @coscialab.bsky.social, @kusterlab.bsky.social, @anamdv.bsky.social, @jsandow.bsky.social
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Reposted by Coscia Lab
British Society for Proteome Research @ukbspr.bsky.social · 13/02/2025
Our selected speakers doe rhe different sessions are: Georg Kustacher - bioinformatics @coscialab.bsky.social single cell/spatial session Manuel Mayr - clinical proteomics Richard Seltema - structural Freddie Theodolou - non-human proteomics Jyoti Choudary - functional proteomics
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Reposted by Coscia Lab
Itai Yanai @itaiyanai.bsky.social · 27/02/2025
"Innovations in Single Cell Omics" Berlin 5.12-13. Keynote Speakers: @shalinhnaik.bsky.social Pulin Li, and me! Invited Speakers: @emmanuel-saliba.bsky.social @mratz.bsky.social Barbara Grünwald Maria Colomé-Tatché Mohammad Lotfollahi @coscialab.bsky.social Teresa Krieger www.isco-conference.eu
isco-conference.eu
ISCO - ISCO
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Coscia Lab @coscialab.bsky.social · 26/02/2025
Wonderful group dinner tonight, #proudPImoment ☺️🫶
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Coscia Lab @coscialab.bsky.social · 30/01/2025
Next up at the @fogenomics.bsky.social proteomics stage, @ajbrenes.com talking about single-cell proteomics applied to neutrophils. Cool stuff!
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Coscia Lab @coscialab.bsky.social · 08/12/2024
Extremely happy that our Deep Visual Proteomics pipeline is one of the highlighted @naturemethods.bsky.social Spatial Proteomics approaches! 🥳 Congrats to the growing DVP team(s)! Making it broadly accessible & advancing it to the multiomics space is a key mission in our lab @mdc-berlin.bsky.social
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