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Reposted by Melissa Klingeberg

PastelBio @pastelbio.bsky.social · 18/11/2025

Pho-Tip: one-pot dephosphorylation for rapid and sensitive analysis of DIA phosphoproteomics data www.biorxiv.org/cont... --- #proteomics #prot-preprint

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Reposted by Melissa Klingeberg

Coscia Lab @coscialab.bsky.social · 20/03/2025

Our lab's newest preprint is out on deep spatial proteomics of ovarian cancer precursor lesions! We demonstrate how ultrasensitive discovery proteomics can shed light onto early carcinogenesis, uncover cell-of-origin signatures, and prioritize novel drug targets. bit.ly/41M7fke

biorxiv.org

Deep spatial proteomics of ovarian cancer precursor lesions delineates early disease changes and cell-of-origin signatures

High-grade serous ovarian cancer (HGSOC) is a devastating disease that is frequently detected at an advanced and incurable stage. Advances in ultrasensitive mass spectrometry-based spatial proteomics ...

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Reposted by Melissa Klingeberg

Vadim Demichev @vadim-demichev.bsky.social · 03/03/2025

Our News & Views on the recent advances in high-coverage single-cell proteomics (on Orbitrap Astral) www.nature.com/articles/s41...

nature.com

Entering the era of deep single-cell proteomics - Nature Methods

Advances in single-cell proteomics allow quantification of half of the expressed proteome in an individual cell.

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