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Yuki Murai

@yukimurai.bsky.social
21 followers 35 following 4 posts

Medical student at Kyoto University | Researching synaptic plasticity and memory consolidation

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Reposted by Yuki Murai
Science Magazine @science.org · 13/08/2026
Memories can survive even after the brain temporarily loses more than half of its synaptic connections, according to a new mouse study in Science, which challenges the long-held view that long-term memories depend on stable individual synapses. Learn more: scim.ag/4zhsCK2
scim.ag
Artificial hibernation reveals synaptic engram architecture associated with memory retention
Memories leave lasting physical changes at the synaptic level. Although stable, larger spines are thought to support memory, the high turnover of dendritic spines and the drifting of neuronal represen...
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Yuki Murai @yukimurai.bsky.social · 31/03/2026
After a great time in Toronto, I spent the last four months of my gap year at Tom(@tommchugh.bsky.social)’s lab at RIKEN CBS. Thanks to Tom and the kind lab members, I made much progress on my project and gained a lot of experience and insight. Thank you for this wonderful opportunity!
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Reposted by Yuki Murai
Tomoaki Okami @tcmckcm.bsky.social · 20/03/2026
[Cell cover] New issue of Cell out today, with my cover illustrating “Whole-organ and whole-body 3D atlases enable cellome-wide profiling.” Congratulations to Dr. Ueda, Yoshida-san and Matsumoto-san!!🎉
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Yuki Murai @yukimurai.bsky.social · 28/11/2025
Today was the final day of my three-month stay in Paul and Sheena’s lab. It was short, but filled with unforgettable moments. I love the lab, the people, and this city. I can’t put into words how grateful I am for everything. Thank you so much, @franklandlab.bsky.social and @sjo09.bsky.social
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Reposted by Yuki Murai
Paul Frankland @franklandlab.bsky.social · 22/10/2025
New paper from the lab 🚨 Led by Ali Golbabaei, this study explores the how the composition of prefrontal cortical engrams changes with memory age: authors.elsevier.com/a/1lzT-3BtfH...
authors.elsevier.com
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Reposted by Yuki Murai
Takeshi Sawada @tsawada.bsky.social · 13/11/2025
Excited to share our new preprint: Blockade of associative spine enlargement impairs awake cortical function biorxiv.org/content/10.1...
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Reposted by Yuki Murai
Paul Frankland @franklandlab.bsky.social · 01/10/2025
New paper from the lab led by Ali Golbabaei. If you’re interested in systems consolidation, generalization and hippocampal neurogenesis a short 🧵 follows: authors.elsevier.com/a/1lsO73QW8S...
authors.elsevier.com
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Yuki Murai @yukimurai.bsky.social · 02/09/2025
Arrived in Toronto!!
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Reposted by Yuki Murai
Paul Frankland @franklandlab.bsky.social · 14/05/2025
Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation. rdcu.be/el18q A short thread follows for those interested. 1/n
rdcu.be
Systems consolidation reorganizes hippocampal engram circuitry
Nature - A study shows that loss of memory precision associated with systems consolidation can be explained by neurogenesis-dependent reorganization of engram circuitry within the hippocampus over...
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Yuki Murai @yukimurai.bsky.social · 05/03/2025
I’m excited to share my first review! I explore diverse synaptic mechanisms underlying episodic memory, with a special focus on an optogenetic tool for canceling LTP induction, established by my wonderful mentors. I’d love to hear your thoughts and feedback! www.sciencedirect.com/science/arti...
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