Picornaviruses are one of the leading agents of animal and human infectious disease with at least 8 billion infections a year and cause a range of symptoms including respiratory failure and acute flac...

In this Journal Club, Yousuf A. Khan recounts a landmark study published in 1985 by Jacks and Varmus that documented programmed ribosomal frameshifting in retroviruses, which later inspired Yousu...

Samples returned from asteroid Bennu contain bio-essential sugars such as ribose and glucose that may have formed in the parent asteroid from brines containing formaldehyde, according to a geochemical...

This year’s awardees are researching cancer treatments, age-related disease, and much more.

Yousuf A. Khan (YAK) Lab - Studying RNA folding, interactions, and cellular effects using Molecular and Cellular Physiology, Structural Biology, and Machine Learning at Stanford University

Rao et al. identified thousands of previously unknown 2A peptides across both viruses and eukaryotes using an HMMER analysis. The authors further identified a unique class of 2A peptides, class B, who...

Google Colab offers free Colab Pro for students, interactive slideshows and AI controls in notebooks.

Nature Structural & Molecular Biology, Published online: 02 July 2025; doi:10.1038/s41594-025-01590-wKhan et al. show that Sec18 uses both D1 and D2 AAA+ rings cooperatively, opening them laterally for SNARE substrate loading and for subsequent release of SNAREs.

Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a mechanism th...